• Fisheries and Aquatic Sciences
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• 제17권4호
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• pp.479-486
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• 2014

To evaluate their potential utility as an ornamental organism, novel transgenic marine medaka Oryzias dancena strains with a highly vivid fluorescent phenotype were established through transgenesis of a cyan fluorescent protein gene (cfp) driven by the endogenous fast skeletal myosin light chain 2 gene (mlc2f) promoter. The transgenic marine medaka strains possessed multiple copies of transgene integrants and passed their fluorescent transgenes successfully to subsequent generations. Transgenic expression in skeletal muscles at both the mRNA and phenotypic levels was, overall, dependent upon transgene copy numbers. In the external phenotype, an authentic fluorescent color was dominant in the skeletal muscles of the transgenic fish and clearly visible to the unaided eye. The phenotypic fluorescent color presented differentially in response to different light-irradiation sources; the transgenics displayed a yellow-green color under normal daylight or white room light conditions, a strong green-glowing fluorescence under ultraviolet light, and a cyan-like fluorescence under blue light from a light-emitting diode.

• 한국수산과학회지
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• 제53권4호
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• pp.563-565
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• 2020

Turbot Scophthalmus maximus can be cultured at a higher density and has a faster growth rate than olive flounder Paralichthys olivaceus, making it an attractive alternative for flounder farmers in Korea. As it is a relatively new species to Korean farming environments, there is no general farming protocol, which takes multiple generations to develop, for turbot in Korea. Nevertheless, we applied breeding technology to develop a stock, which we considered first-generation turbot. Then we compared its growth rate (an important economic trait) to different populations (the original stock of Korean turbot, French turbot, and Chinese turbot). The four different populations were grown in similar culture conditions. First-generation Korean turbots grew about 28% faster than all others. We will continue to select for important traits such as color, disease resistance, and heat tolerance in this turbot broodstock; we believe that with the appropriate selection process, Korean turbot should become competitive in the markets, and will become a major farming species in the Korean aquaculture industry.

• Asian-Australasian Journal of Animal Sciences
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• 제15권6호
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• pp.767-771
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• 2002

Breeding efficiencies were compared among three population schemes: a single population, a population with two subpopulations and a population with three sub-populations. A simulation experiment of selection was carried out for 10 generations with 20 replications each by comparing average breeding values and inbreeding coefficients among the three population schemes. Phenotypes of three traits were generated with a model comprising 36 loci, each with additive genetic effects and residuals distributed normally. Among the three population schemes, the single population scheme was definitely superior to the other two with regards to selection response and inbreeding. The multiple sub-population scheme was, however, considered to be an alternative population scheme when the difference in economic weights of the traits was small among the sub-populations, assuming moderate inbreeding depression for traits and crossbreeding. The scheme with two sub-populations had a higher genetic value than that with three subpopulations; however, the genetic values of the schemes were comparable when maternal heterosis was taken into account. The choice of population schemes may depend on the cost-sharing policy between the breeding population and the commercial population rather than just the breeding efficiency.

• 보건의료산업학회지
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• 제10권4호
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• pp.97-107
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• 2016

Objectives : This study aims to : (i) characterize and differentiate between two different periods of baby boomers, (ii) study the utilization of their health care services, and (iii) establish effective ways of providing better health service utilization and preventive policy strategies for upcoming and older generations. Methods : A multiple regression analysis using descriptive statistics, frequency analysis, and dummy variables was utilized to access the presence of correlations between socio-demographic factors and health care service utilization. Results : Medical insurance type, marital status, and chronic disease were factors that influenced health care service utilization. Furthermore, the factors that influenced individual medical expenses were cohabitation, inpatient days, and chronic disease. Conclusions : Primary findings and exploratory statistics revealed that there were strong correlations and interaction among some of the predictor variables. Because of the chronologically limited nature of the sample data set gathered in 2012, it would be helpful to continue to develop or research related constructs that may capture relationships more effectively among extended populations.

• 한국CDE학회논문집
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• 제22권1호
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• pp.10-17
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• 2017

The recent 3D printing industry has been focusing on developing 3D printers to fulfill the user's need to bring more colorful and realistic outcomes. Several 3D printers have deployed multiple extruders to print different colors. However, this method has a limit on its availability of colors. To solve this, recent research is focused on using mixing chambers to mix the possible colors to provide more color availability. In this paper, we discuss the environment and algorithm behind the development of G-code which allows a gradation effect of the mix of two filaments. The generation algorithm to make gradient G-code has been implemented in Cura using C ++ and Python.

• 한국태양에너지학회 논문집
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• 제33권5호
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• pp.34-40
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• 2013

Islanding phenomenon of photovoltaic system is undesirable because it leads to a safety hazard to utility service personnel and may cause damage to power generation and power supply facilities as a result of unsynchronized re-closure. Anti-islanding protection is an important technical requirement for grid-connected PV system. Until now, various anti-islanding methods for detecting and preventing islanding of photovoltaic and other distributed generations have been proposed. Most of them are focusing on the anti-islanding performance of single PV system according to the related international and domestic standard test procedures. There are few studies on the islanding phenomenon for multiple photovoltaic operation in parallel. This paper presents performance analysis of anti-islanding function for grid-connected PV inverter systems when several PV inverters are connected in parallel.

• 생명과학회지
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• 제30권9호
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• pp.798-803
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• 2020

1960년대 후반 인디카 품종과 자포니카 품종의 교잡에 의하여 새로운 통일형 벼 품종을 육성했고 그 재배기술을 확립했으며, 현재까지 이 재배기술을 이용하여 소비자들의 기호에 맞게 그리고 극한환경에 대응할 수 있는 다양한 품종들이 만들어졌다. 서로 다른 작물끼리 교배하여 얻은 F₁을 가지고 반복적인 세대 진전을 통하여 도입을 원하는 우량한 유전자원의 형질이 더 이상 분리되지 않을 때 교배시킨 형질이 고정되었다고 볼 수 있으며 비로소 신품종이 될 수 있다. 본 연구에서는 가뭄에 저항성을 띠는 HV23 계통을 모품종인 Ilmi와 교배한 집단과 벼멸구에 내성을 갖는 Drimi2ho와 교배한 집단의 F₄, F₅, 그리고 F₆의 농업형질을 조사하여 고정 여부를 확인했다. HV23와 Drimi2ho/HV23 계통의 F₅, F₆를 비교하였을 때 그리고 Ilmi/HV23 계통의 F₄, F₅를 비교하였을 때 모두 유의하지 않은 정도의 형질 변이가 나타났기 때문에 농업형질이 고정되었다고 판단할 수 있었다. 일반적인 계통 육종법은 품종개량에 10년 이상의 시간이 드는 반면 본 연구에서는 4-5년 만에 형질이 고정되었음을 확인하였다.

• 한국가금학회지
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• 제17권4호
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• pp.243-254
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• 1990

본 연구는 상업용 목적으로 선발, 유지되어 온 계군에서의 선발에 의한 유전모수 추정치의 변화양상을 살펴보고, 추정된 유전모수를 바탕으로 하여 차세대의 유전적 개량량을 예측한 후 이를 선발결과 나타난 관측치와 비교, 분석하기 위하여 수행되었다. 분석에 이용된 자료는 단관백색레그혼종 1계통(Line-W)과 갈색난용종 1계통(Line-B)에 대한 1980년부터 1986년까지의 5세대간 자료로써 표현형 능력변화와 선발형질들에 대한 유전력 및 유전상관계수를 추정하고, 이들을 바탕으로 하여 추적선발지수방법에 의해 유전적 개량량을 추정하였다. 추정된 각 형질의 유전적 재량량을 살펴 보면, 두 계통에서 초산일령의 경우 각각 세대당 1.67일과 1.14일씩 단축된 것으로 나타났고, 300일령 산란수는 각각 4.15개와 2.37개, 400일령 산란수는 각각 5.92개와 3.73개씩 증가된 것으로 분석되었으며, 30주령시 난중과 40주령시 난중은 거의 변화가 없었던 것으로 나타났다. 이상에서 얻어진 각 형질의 유전적 개량량의 수치는 300일령 산란수 한 형질만을 모가계 선발에 의해 선발한 경우의 유전적 개량량과 유사한 것으로 나타났으며, 추정된 유전적 개량량에 의해 차세대의 능력을 예측한 후 이를 관측치와 비교한 결과 선발 후기세 대(4세대와 5세대)에서 두 계군이 환경의 영향을 크게 받았던 것으로 판단되었다.

• Journal of Genetic Medicine
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• 제6권1호
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• pp.81-86
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• 2009

다발성 골단이형성증은 임상적 및 유전학적으로 이질적인 연골이형성증으로, 골화 중심의 발달 지연, 골단만을 침범하는 사지의 변형 및 경한 저신장을 보이는 질환이다. 원인으로는 COMP 유전자의 돌연변이가 가장 흔히 발견되고 있으며, 돌연변이의 대부분은 칼모듈린 유사 반복(calmodulin-like repeats)부분과 C-말단에 위치한다. 저자들은 4대에 걸쳐 12명의 가족구성원에서 다발성 골단이형성증을 보인 한 가계에서 COMP 유전자 분석으로 새로운 돌연변이를 발견하여 보고하는 바이다. 이 가계는 젊은 나이에 퇴행성 관절염이 발생하고, 추후 관절치환술이 요구되는 상염색체 우성 유전 방식을 보이는 질환을 가지고 있었다. 방사선학적 검사상 양측 무릎 관절의 내측 대퇴돌기에 골연골 결손을 보였으며, 양측 무릎과 엉덩이 관절은 다양한 정도의 퇴행성 변화가 관찰되었다. 계보발단자 및 5명의 다른 이환된 가족들에서 시행한 COMP 유전자 분석에서, 12번째 엑손에서 현재까지 보고되지 않은 새로운 돌연변이인 c.1280G>C (p.Gly427Ala)을 확인하였다. 이 돌연변이는 다른 3명의 이환되지 않은 가족들에서는 발견되지 않았다. 상염색체 우성 방식을 보이는 다발성 골단이형성증 환자들에서 COMP 유전자의 직접 염기서열 분석법은 질병의 원인이 되는 돌연변이를 찾는데 도움이 되며, 고위험 가족들에서 보인자를 찾아낼 수 있고, 질병의 합병증이 발생하기 이전에 조기 진단 및 중재를 가능케 하는 유전 상담의 기회를 제공해 줄 수 있다.

• Archives of Plastic Surgery
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• 제37권2호
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• pp.178-181
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• 2010

Purpose: Retronychia is the embedding of the nail into proximal nail fold. Retronychia starts with disruption of the longitudinal growth of the nail. With the growth of a new nail, the old one is pushed upwards and backwards. This leads to embedding of the top nail into the ventral aspect of the proximal nail fold and results with chronic paronychia. We present a case of retronychia that was rarely reported in the literature. Methods: A 46-year old female presented with a 3-month history of painful right first, 2nd, 3rd toenail changes. Although she was initially treated with broad spectrum antibiotics, she did not response to therapy. Later, she presented to our department because of progressively worsening pain that impaired her walking. Physical examination revealed with proximal nail fold erythema, painful swelling, yellowish nail discoloration, and distal onycholysis. Bacterial and fungus culture showed no organism. Treatment was surgical nail avulsion under local anesthesia. Results: The postoperative course was uneventful. 10 months later, the patient had a normal growing nail and was free of symptoms. Conclusion: We report a case of retronychia on toenail. Retronychia is a proximal nail plate ingrowth into the proximal nail fold which is associated with multiple generations of nail plate misaligned beneath the proximal nail. Management consisted of simple avulsion of superimposed nail. Retronychia is suspected with a persistent paronychia, particularly in the setting of trauma. Avulsion of the top nail confirms the diagnosis and may be curative if the underlying nail appears healthy.