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Steatocystoma multiplex: A case report of a rare entity

  • Shin, Nan-Young;Kang, Ju Hee;Kim, Jo-Eun;Symkhampa, Khantaly;Huh, Kyung-Hoe;Yi, Won-Jin;Heo, Min-Suk;Lee, Sam-Sun;Choi, Soon-Chul
    • Imaging Science in Dentistry
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    • v.49 no.4
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    • pp.317-321
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    • 2019
  • Steatocystoma multiplex is an uncommon benign skin disease, which typically manifests as numerous intradermal cysts that can be scattered anywhere on the body. Although usually asymptomatic, it can be significantly disfiguring. One type of steatocystoma multiplex is known to be associated with the autosomal dominant inheritance of a mutation in the gene coding for keratin 17 (KRT17). In such cases, it is often concurrent with other developmental abnormalities of the ectoderm-derived tissues, such as the nails, hair, and teeth. To the best of our knowledge, few cases have been reported of steatocystoma multiplex of the oral and maxillofacial region. This report describes a case of steatocystoma multiplex of both sides of the neck and multiple dental anomalies, with a focus on its clinical, radiological, and histopathological characteristics, as well as the possibility that the patient exhibited the familial type of this condition.

Design of No-human-in-the-Loop Battleship Warfare M&S System applied to the Korea Yellow Sea Warfare Case using Agent-based Modeling (에이전트 기반의 인간 미개입형 함정전투 M&S 시스템 설계 및 서해교전 사례연구)

  • Chi, Sung-Do;You, Yong-Jun;Jung, Chan-Ho;Lee, Jang-Se;Kim, Jae-Ick
    • Journal of the Korea Society for Simulation
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    • v.17 no.2
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    • pp.49-61
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    • 2008
  • Most battleship warfare M&S systems run relatively slow and the simulation results are often unfair since the system should interact with human operators(controller and/or gamer). To deal with these problems, we have proposed the agent-based battleship warfare M&S system which interact with multiple agent systems instead of human operators. Agent-based M&S system may be able to efficiently support the analysis of effectiveness and/or the operational tactics development of given warfare by providing autonomous reasoning capabilities without the intervention of human controller. To do this, the paper propose the design concept and methodology using the advanced modeling and simulation framework as well as autonomous agent design principle. Several simulation tests performed on the battleship warfare case study on Korea Yellow sea will illustrate our techniques.

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A Case of Recurrent Pulmonary Inflammatory Myofibroblastic Tumor with Aggressive Metastasis after Complete Resection

  • Moon, Chae Ho;Yoon, Jong Ho;Kang, Geon Wook;Lee, Seong Hyeon;Baek, Jeong Su;Kim, Seo Yun;Kim, Hye-Ryoun;Kim, Cheol Hyeon
    • Tuberculosis and Respiratory Diseases
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    • v.75 no.4
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    • pp.165-169
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    • 2013
  • An inflammatory myofibroblastic tumor (IMT) is a rare disease entity reported to arise in various organs. It is thought to be a neoplastic or reactive inflammatory condition, controversially. The treatment of choice for myofibroblastic tumor is surgery, and recurrence is known to be rare. The optimal treatment method is not well-known for patients ineligible for surgery. We report a 47-year-old patient with aggressive recurrent IMT of the lungs. The patient had been admitted for an evaluation of back-pain two years after a complete resection of pulmonary IMT. Radiation therapy was performed for multiple bone recurrences, and the symptoms were improved. However the patient presented again with aggravated back-pain six months later. High-dose steroid and non-steroidal anti-inflammatory drugs were administered, but the disease progressed aggressively, resulting in spinal cord compression and metastasis to intra-abdominal organs. This is a very rare case of aggressively recurrent pulmonary IMT with multi-organ metastasis.

Primary Thyroid Lymphoma: Multi-Slice Computed Tomography Findings

  • Li, Xu-Bin;Ye, Zhao-Xiang
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.1135-1138
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    • 2015
  • Background: The objective of this study was to investigate the MSCT characteristics of PTL in order to enhance the awareness of this uncommon entity among both clinicians and radiologists. Materials and Methods: The clinicopathological data and MSCT images of 27 patients with PTL were retrospectively reviewed. The MSCT appearances were classified into three types: type 1, solitary nodule surrounded by normal thyroid tissue; type 2, multiple nodules in the thyroid, and type 3, enlarged thyroid glands with a reduced attenuation with or without peripheral thin hyperattenuating thyroid tissue. Results: The patients were enrolled in the study with a mean age of 68 years (range, 51-86years) and compression symptoms or enlarged cervical lymph nodes at diagnosis. Hashimoto's thyroiditis was in 20 patients. All patients had non-Hodgkin lymphoma of B-cell in origin, including 22 cases of diffuse large B-cell lymphoma (DLBCL) and 5 of low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). For MSCT appearance, type 1 pattern was observed in 2 patients, type 2 in 8, and seventeen type 3 in 17. The lesions occurred in more than one lobe with a mean maximal transverse diameter of 6.9 cm and an ill-defined margin. Most tumors showed a homogeneous attenuation equal to that of surrounding muscles before contrast and obvious enhancement after contrast. Cervical lymph node involvement and invasion of the trahea and (or) esophagus were mainly observed in patients with DLBCL. Conclusions: PTL should be clinically considered in elder patients presenting with a history of Hashimoto's thyroiditis and cervical lymphadenopathy. The MSCT characteristics of PTL includes a mass diffusely affecting more than one thyroid lobe, isointense to muscle and obvious enhancement before and after contrast. DLBCL, the most common histological subtype of PTL, is associated with a higher invasive tendency.

Object Oriented Spatial Data Model using Geographic Relationship Role (지리 관계 역할을 이용한 객체 지향 공간 데이터 모델)

  • Lee, Hong-Ro
    • Journal of Internet Computing and Services
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    • v.1 no.1
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    • pp.47-62
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    • 2000
  • Geographic Information System(GIS) deal with data which can potentially be useful for a wida range of applications. However, the information needs of each application usually vary, specially in resolution, detail level, and representation style, as defined in the modeling phase of the geographic database design. To be able to deal with such diverse needs, the GIS must after features that allow multiple representations for each geographic entity of phenomenon. This paper addresses the problem of formal definition of the objects and their relationships on geographical information systems. The geographical data is divided in two main classes: geo-objects and geo-fields, which describe discrete and continuous representations of spatial reality. I will study the classes and the roles of relationships over geo-fields, geo-objects and nongeo-objects. Therefore, this paper will contribute the efficient design of geographical class hierarchy schema by means of formalizing attribute-domains of classes.

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Calcifying Aponeurotic Fibroma Occurring on the Chin: A Case Report (턱에 발생한 석회화건막섬유종 : 증례보고)

  • Jung, Yun Joo;Choi, Young Woong;Shin, Eun Ah
    • Archives of Plastic Surgery
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    • v.35 no.1
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    • pp.104-106
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    • 2008
  • Purpose: Fewer than 100 cases of calcifying aponeurotic fibroma have been reported in the literature since this entity was initially described by Keasbey in 1953 who called it calcifying juvenile aponeurotic fibroma. The tumor is a slowly growing, painless mass. In most cases the mass is poorly circumscribed and causes neither discomfort nor limitation of movement. Most lesions occur in children, with a peak incidence ages of 8-14 years. There is no evidence of any increased familial prevalence. Predilection sites are palm, finger, toe, but it also occurs in the wrist, forearm, elbow, upper arm, neck, abdominal wall, lumbar paravertebral area, leg and ankle. We herein describe a rare case of calcifying aponeurotic fibroma occurring on the chin with review of the literature. Methods: A 14-year-old male had painless, slowly growing mass(${\phi}2.5cm$) on a chin for a year. The tumor was excised elliptically under local anesthesia and the excisional site was repaired directly. Due pathological examination was processed. Results: Histological examination revealed an illdefined fibrous growth that extends with multiple processes into the surrounding tissue with centrally located foci of calcification. The tumor is composed of short spindled plump fibroblasts with round or ovoid nuclei separated by collagenous stroma, showing vaguely palisading pattern. Diagnosis of calcifying aponeurotic fibroma was conferred. Postoperatively, the patient did well, and the lesion had not recurred. Conclusion: Fewer than 100 cases of calcifying aponeurotic fibroma have been reported in the literature. The most common occurring sites are palm, finger & toe, but it has been reported in the wrist, forearm, elbow, upper arm, neck, abdominal wall, lumbar paravertebral area, leg and ankle. Two cases of calcifying aponeurotic fibroma occurring on the neck have been reported in the literature. To the authors knowledge, our case of calcifying aponeurotic fibroma occurring on the chin is the first to be reported.

Clinical Study of Subacute Necrotizing Lymphadenitis (아급성 괴사성 림프절염의 임상적 고찰)

  • Chu Ho-Suk;Jung Eun-Jae;Woo Jeong-Su;Hwang Soon-Jae;Lee Heung-Man
    • Korean Journal of Head & Neck Oncology
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    • v.19 no.2
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    • pp.133-136
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    • 2003
  • Background and Objectives: Kikuchi's disease or subacute necrotizing lymphadenitis is a cause of persistently enlarged lymph nodes unresponsive to antibiotic therapy. It affects predominantly young women under the age of 30, and it is seen primarily in the Asian population. Although this disease usually follows a benign course, all describing a clinical entity that has been mistaken for malignant lymphoma, lupus, and an assortment of infectious diseases. The purpose of this study is to report clinical characteristics and treatment outcome in order to contribute to the precise diagnosis and treatment. Materials and Methods: We reviewed 27 cases, who were diagnosed as subacute necrotizing lymphadenitis on excisional biopsy during the past 5 years from January 1998 to December 2002. Results: It occurred more often in females (20 cases ; 74%) than males (7cases ; 26%), and it was seen more frequently in the second and third decades (21 cases ; 78%). Cervical lymphadenopathy were usually multiple (24 cases, 89%) and measured less than 2cm (20 cases, 74%). The posterior cervical and deep jugular chains are the most common location(34 cases ; 81%). Leukopenia(18 cases, 67%) and elevated ESR(20 cases, 75%) were commonly noted in laboratory data. Conclusions: It is easy that Kikuchi's disease is mistaken for malignant lymphoma. So we should consider fine needle aspiration or open biosy of lymph node for histologic diagnosis in patients who have localized cervical lymphadenopathy unresponsive to antibiotic therapy.

A Clinical Consideration of Necrotizing Lymphadenitis (괴사성 림프절염에 대한 임상적 고찰)

  • 유명종;조우령;김학선;이재동;김명구
    • Korean Journal of Bronchoesophagology
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    • v.6 no.2
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    • pp.164-171
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    • 2000
  • Background and Objectives: Necrotizing lymphadenitis or Kikuchi's disease is characterized by cervical lymphadenopathy of unknown etiology with unique histologic findings in young female patients. The importance of this disease lies in the fact that it can be easily misdiagnosed as malignant lymphoma, hence, clinicians need to aware of this disease entity. The purpose of this study is to report the clinicopathologic findings, radiographic findings, and many laboratory tests in order to contribute to the diagnosis and treatment of necrotizing lymphadenitis. Materials and Methods: We evaluated 31 patients, who were diagnosed as necrotizing lymphadenitis by excisional biopsy or fine needle aspiration cytology or ultrasound guided 18G cutting needle biopsy, retrospectively. Result : The median age was 24.8 years (range 12 to 43 years) and the male to female ratio was 1 : 2.4(9:22), with 14 females (45.1%) under 30 years. The common chief complaints were neck mass, easy fatigue and fever. Lymph node enlargement was limited to the cervical area in most cases (28cases : 90.3%). The involved lymph nodes were usually multiple (20cases : 64.5%), unilateral (26cases 83.9%) and small sized. Leukopenia (19cases : 61.3%) and elevation of ESR (18cases : 58.1%) appeared most frequently in the abnormal laboratory data. These symptoms will be gone spontaneoulsy without any specific treatment in several weeks or months. Conclusion : We should consider open biopsy or fine needle aspiration cytology or ultrasound guided cutting needle biopsy with lymph node in patients who have cervical lymphadenopathy with easy fatigue and fever, especially young women to exclude other conditions such as malignant lymphoma and tuberculosis, etc.

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A Study on the Activation Method of ICT-Based Video Record Management and Utilization (ICT기술을 활용한 동영상 기록관리 및 이용의 활성화 방안 연구)

  • Lee, Sang hyuen;Byeon, Seon yeong;You, Hyeon jeong;Park, Choon won
    • Journal of Korean Society of Archives and Records Management
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    • v.18 no.2
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    • pp.215-242
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    • 2018
  • The record continuum theory is now being studied in Australia, wherein the segregated record management of current, semi-current, and past records based on the temporal flow of the life cycle theory are being critcized. In addition, it emerged as a new paradigm for electronic record management without time and spatial constraints. Moreover, it is recognized as a logical and conceptual entity rather than as a fixed physical object. It also makes it possible to record multiple records in consideration of the complex, multidimensional environment of records. Based on this record continuation theory, the current information and communications technology (ICT) is applied to the four axes and dimension of the record continuation diagram of theoretical researcher Frank Upward. The researchers aim to realize a video recording management method suitable for the electronic record age.

MULTILOCULAR UNICYSTIC AMELOBLASTOMA ASSOCIATED WITH DENTIGEROUS CYST (함치성 낭종과 연관된 다방성의 낭종성 법랑아세포종)

  • Lee, Jae-Hwy;Oh, Seong-Seob
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.14 no.1_2
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    • pp.160-168
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    • 1992
  • Ameloblastoma is an aggressive but benign epithelial neoplasm of odontogenic origin, and the occurrence of odontogenic epithelium in the wall of a dentigerous cyst is well-known entity. The presence of ameloblastic proliferation in the walls of odontogenic cysts has been reported for many years. Cahn in 1933 described a case in which he considered an ameloblastoma to have originated in a dentigerous cyst, and numerous other cases of ameloblastomatous proliferation have since been reported. In 1977, Robinson and Martinez described a distinct variant of ameloblastoma in which the response to curettage was found to be favorable with a recurrence rate of 25%. The gross and microscopic features indicated that this variant vas associated with a large cystic cavity with either luminal or mural proliferation of ameloblastic tumor cells, and they referred to this variant as unicystic ameloblastoma. Unicystic ameloblastoma occurs most commonly in the second and third decades of life, which is considerably younger than the average age of discovery for the classical ameloblastoma. For the accurate histopathological diagnosis of the unicystic ameloblastoma, the specimen obtained the excisional biopsy, complete enucleation or incisional biopsy from the multiple site of the lesion. This article provides histopathologic evidence of multilocular unicystic ameloblastoma in which ameloblastic tissue was associated with a dentigerous cyst that was found in a 31-year-old female, and complete radiographic, photographic, and microscopic documentation is presented.

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