MULTILOCULAR UNICYSTIC AMELOBLASTOMA ASSOCIATED WITH DENTIGEROUS CYST

함치성 낭종과 연관된 다방성의 낭종성 법랑아세포종

Ameloblastoma is an aggressive but benign epithelial neoplasm of odontogenic origin, and the occurrence of odontogenic epithelium in the wall of a dentigerous cyst is well-known entity. The presence of ameloblastic proliferation in the walls of odontogenic cysts has been reported for many years. Cahn in 1933 described a case in which he considered an ameloblastoma to have originated in a dentigerous cyst, and numerous other cases of ameloblastomatous proliferation have since been reported. In 1977, Robinson and Martinez described a distinct variant of ameloblastoma in which the response to curettage was found to be favorable with a recurrence rate of 25%. The gross and microscopic features indicated that this variant vas associated with a large cystic cavity with either luminal or mural proliferation of ameloblastic tumor cells, and they referred to this variant as unicystic ameloblastoma. Unicystic ameloblastoma occurs most commonly in the second and third decades of life, which is considerably younger than the average age of discovery for the classical ameloblastoma. For the accurate histopathological diagnosis of the unicystic ameloblastoma, the specimen obtained the excisional biopsy, complete enucleation or incisional biopsy from the multiple site of the lesion. This article provides histopathologic evidence of multilocular unicystic ameloblastoma in which ameloblastic tissue was associated with a dentigerous cyst that was found in a 31-year-old female, and complete radiographic, photographic, and microscopic documentation is presented.

저자는 31세 여자환자의 좌측하악부에서 매복된 제3대구치 주위의 함치성 낭종에서 기원한 Group 3a type의 다방성의 낭종성 법랑아세포종을 경험하여 병소에 포함된 치아 발거슬 및 enucleation/curettage로 현재까지 재발없이 치유되었기에 병리조직학적 소견을 중심으로 문헌고찰과 함께 보고하는 바이다.