• 한국의학물리학회지:의학물리
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• 제5권2호
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• pp.49-55
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• 1994

Conformal therapy를 위해 필수적이라 할 수 있는 Multileaf collimator(MLC)는 기존의 cerrobend에 의해 형성되는 선량 분포에 비해 leaf 폭의 제한 때문에 조사면의 경계 부분의 반그림자를 증가시키는 결과를 초래한다. 이러한 scallop penumbra의 변화를 알아보기 위해 본 연구에서는 MLC에 의해 형성되는 모양의 field를 cerrobend 블럭을 이용하여 제작, 다양한 형태의 field 모양에 따른 기존의 블럭과 MLC블럭에 의한 penumbra의 차이를 비교해 보고 이를 통해 임상적으로 사용 가능한 최적의 leaf 폭을 찾아내었다. MLC 제작시의 비용을 고려할 때 leaf 폭이 8 mm가 적당함을 알 수 있었다.

• 한국의학물리학회지:의학물리
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• 제5권2호
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• pp.45-48
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• 1994

방사선 치료분야에서 Conformal Therapy에 이용되는 Multileaf Collimator(MLC) leaf 폭 분포에 관한 연구를 하였다. 이미 방사선 치료를 받은 303명 환자의 1169 치료 조사면 차폐 블럭 사용빈도 유형을 조사하여 block 사용빈도가 잦은 곳은 leaf 폭을 좁게 배치하고, 사용빈도가 성긴 곳은 leaf 폭을 두껍게 배치하였다. 전체 leaf 폭 평균은 0.8 cm이되, 실제 차폐 블럭 사용빈도가 높은 부위(치료중심에서 3-6 cm)에서는 MLC leaf 폭이 0.5-0.6 cm의 치료 효과를 볼 수 있도록 불균일 leaf 폭 분포를 갖는 MLC를 고안하였다.

• 대한방사선기술학회지:방사선기술과학
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• 제21권1호
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• pp.24-28
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• 1998

A conventional treatment machine shapes x-ray fields by a set of dense metal collimators(jaws) built into the machine. These collimators are positioned by the therapist using hand controls in the treatment room, and usually remain stationary during treatment. The collimator jaws of treatment machines produce rectangular beams. Conventional beam shaping is accomplished through the use of a combination of these collimator jaws and secondary custom beam blocks attached to the accelerator beyond the collimator Jaws. The jaw positions for a particular field can be retrieved from a computer. One application of this increased capability is replacement of beam blocks for field-shaping with the MLC. There are three basic applications of the MLC. The first application is to replace conventional blocking. A second function of the MLC is related to conformal therapy, adjusting the field shape to match the beam's eye view projection of a planning target volume during treatment. The third application is the use of the MLC to achieve beam intensity modulation. The aim of this paper is to provide basic principle and to state fundamental concepts needed to implement the use of a multileaf collimator in the conventional clinical setting. The use of MLC field shaping is likely to save time and to incur a lower operating cost when compared to the use of beam blocks.

• 대한방사선치료학회지
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• 제10권1호
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• pp.88-93
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• 1998

Multileaf collimator is essential equipment in conformal radiation therapy, however the use is limitted by increase of penumbra width and undulating dose distribution at the field edge. The purpose of this study is to improve the penumbra and dose distribution in the multileaf collimator field edge. Measurement were performed with X-omat V film in solid water phantom using 6MV photon beam from Siemens linear accelerator. All the measurement were made along the central axis of $5{\times}5cm,\;10{\times}10cm$ circular field for constant SSD of 100 cm. To improve the penumbra and dose distribution collimator was rotated by 15 degrees from 0 to 90 degrees (collimator rotation method) and center was shifted to the longitudinal direction by fourth of lead width (center shift method). We compare the penumbra and dose distribution at the field edge to alloy block. Dose distribution and penumbra width at the feild edge of MLC showed undulated dose pattern and increased penumbra compared with alloy block. However, in the collimator rotation method and center shift method we abtained simular results with alloy block. Through the study we expected that clinical use of MLC will be increase.

• 한국의학물리학회지:의학물리
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• 제22권1호
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• pp.3-11
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• 2011

본 연구에서는 제작한 수직형 다엽 콜리메이터를 이용하여 방사선치료에 사용되는 Co-60 감마선 및 6 MV 엑스선의 조사면 크기와 모양을 결정하고 동일한 모양 및 크기의 조사면을 납차폐체로 결정하여 방사선 조사면 내 선량분포 특성을 상호 분석하여 수직형 다엽 콜리메이터의 방사선 조사면 크기 결정에 관한 유용성을 평가하였다. 이를 위해 이온전리함, 유리선량계, 방사선크로믹 필름을 사용하여 선량측정 실험을 수행하였다. Co-60 감마선과 6 MV 엑스선에 대하여 기준조사면의 이온전리함 측정결과 수직형 다엽 콜리메이터의 빔 중심축 선량값이 납차폐체의 선량값보다 각각 5.1%, 4.2% 높게 측정되었다. 그리고 Co-60 감마선에 대한 4개 조사면(기준 조사면, 원형, 삼각형, 십자형)의 유리선량계 측정 결과는 수직형 다엽 콜리메이터의 선량값이 납차폐체의 선량값보다 각각 2.2%, 7.8%, 7.2%, 4.0% 높게 측정되었고, 6 MV 엑스선에 대하여는 수직형 다엽 콜리메이터의 선량값이 납차폐체의 선량값보다 각각 6.7%, 6.2%, 3.8%, 6.2% 높게 측정되었다. 방사선크로믹 필름에서 차폐체의 선량분포곡선 중 최대선량의 80%에서 20%까지의 거리를 나타내는 반음영 크기는 모든 조사면에서 수직형 다엽 콜리메이터의 반음영 크기가 납차폐체보다 Co-60의 경우 2.0~3.5 mm, 6 MV 엑스선의 경우 0.5~1.0 mm 작게 나타났으며 이는 제작한 수직형 다엽 콜리메이터가 임상에 사용되었을 때 반음영의 크기를 납차폐체보다 줄일 수 있음으로써 치료 조사면적 결정시 차폐물의 반음영으로 생기는 방사선치료체적(Treatment Volume, TV)을 최소화시킬 수 있는 장점이 있으리라 판단된다. 아울러 2차원 및 3차원 방사선치료 시 본 다엽 콜리메이터를 이용하여 다양한 방사선치료 조사면을 간편하게 결정하여 사용할 수 있으리라 생각된다.

• 한국의학물리학회지:의학물리
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• 제26권4호
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• pp.223-228
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• 2015

이중으로 집중된 미세 다엽콜리메이터(Double-focused micro Multileaf Collimator: ${\mu}MLC$)는 보통의 다엽콜리메이터(Multileaf Collimator: MLC)에 비하여 조사면 가장자리 부분의 선량을 급격하게 줄여준다. 이러한 특성 때문에, 미세 다엽 콜리메이터는 정위적 방사선 수술과 치료(Stereotactic Radio-Surgery/RadioTtherapy, SRS/SRT)에 사용되어 왔다. 우리는 Elekta Synergy 선형가속기에 이중으로 집중된 동적 미세 다엽콜리메이터(Double-focused Dynamic micro-Multileaf Collimator: DMLC)를 부착하여 선량학적 특성을 평가하였다. 본 연구에서는, 필름(GafChromic EBT2 film), EDGE 다이오드 검출기, 3차원 물 팬텀을 이용하였다. 깊이선량백분율(Percent Depth Dose, PDD), 엽 투과도(leaf leakage), 반그림자(Penumbra)를 측정하였고, 모든 데이터들은 6MV 광자선으로 측정하였다. 그 결과, DMLC가 1% 이내의 투과도를 갖는것을 확인할 수 있었다. DMLC는 이중으로 집중 되는 구조를 가졌기 때문에 반 그림자가 조사야 크기에 대하여 독립적인 것을 확인하였다. 본 연구에서는 DMLC의 선량학적 특성을 바탕으로, Elekta Synergy에 부착된 DMLC의 적용 가능성을 증명하였다.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 춘계학술대회
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• pp.49-51
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• 1996

We have developed the prototype Multi-leaf Collimator(MLC) for Medical linear acclerator. In this study, we have examined the mechanical characteristics of newly developed multileaf collimator. The leaf movement in clinical situation and the modification of accessories is good. such as the block tray mount and the wedges, due to the new MLC installation are efficient. But it was that bolts and nuts for the leaf control should have better performance.

• 한국의학물리학회지:의학물리
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• 제15권1호
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• pp.17-22
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• 2004

Multileaf collimator (MLC) is now rapidly replacing the lead ahoy block to shape the radiation treatment field. In addition to its defect of rectangular field shaping and increased penumbra width, it has another possible problem, and that is of radiation transmission between leaves, which needs to be maintained at as low a level as is permissible. The authors measured and analyzed the inter-leaf and cross-leaf transmissions of MLC by Varian Associates Inc, before its clinical application. The inter-leaf and cross-leaf transmissions were calculated by comparing the measured point doses in the polystyrene phantom in the open field and in a total closure of MLC. The beam profile of the inter-leaf and cross-leaf transmissions were depicted by using a water phantom. A photon beam of 6 MV was used in the measurement. The inter-leaf transmission was 1.63∼1.67%, indicating that the shielding effect of MLC is excellent. However, the cross-leaf transmission in the central area was 18.4∼18.7% and this is well over the clinically acceptable limitation of 5%. The beam profile of cross-leaf transmission displayed 80∼90% transmission near the field edge, so that the cross-leaf transmission was 14∼17% in this area. The multileaf collimator has an excellent shi디ding effect and the inter-leaf transmission is negligible so that it can be used in clinic as a good replacement of the conventional lead alloy block. However, care must be taken to avoid the cross-leaf transmission in the radiation field.

• 대한방사선기술학회지:방사선기술과학
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• 제22권1호
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• pp.61-66
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• 1999

The use of multileaf collimator(MLC) to replace conventional field-shaping techniques is not in itself expected to improve the local control of malignancy. The purpose for using MLCs in conventional radiation oncology is to improve the efficiency of treatment delivery. For effective clinical application of MLCs to shaped radiation field, field outline must be translated into MLC leaf position tables. The intended leaf positions contained in these tables must then be communicated to the control computer that drives the MLC. There are currently at least three techniques utilized by manufacturers of MLCs and treatment planning systems for doing this. The Varian series use a workstation employing a manual digitizer and light box especially. It has a third level MLC configuration and also has the option of placing the wedges above or below the block tray. The C language are used for development of software and three leaf coverage have been used for positioning MLC loaves at the nominal field boundary. The fit of the leaf shape to treatment target volumes are optimized by the rotation of the direction in leaf travel. The clinical application of this software are investigated for Varian MLCs used in linear accelerator of Yonsei Cancer Center. The advantage of the results with using this software is to prescribe and calculate exposed and blocked area in MLCs field.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.74-82
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• 2002

In Intensity Modulated Radiotherapy (IMRT), radiation is delivered in a multiple of Multileaf Collimator (MLC) subfields. A subfield with a small leaf-to-leaf opening is highly sensitive to a leaf-positional error. We introduce a method of identifying and rejecting IMRT plans that are highly sensitive to a systematic MLC gap error (sensitivity to possible random leaf-positional errors is not addressed here). There are two sources of a systematic MLC gap error: Centerline Mechanical Offset (CMO) and, in the case of a rounded end MLC, Radiation Field Offset (RFO). In IMRT planning system, using an incorrect value of RFO introduces a systematic error ΔRFO that results in all leaf-to-leaf gaps that are either too large or too small by (2ㆍΔRFO), whereas assuming that CMO is zero introduces systematic error ΔCMO that results in all gaps that are too large by ΔCMO = CMO. We introduce a concept of the Average Leaf Pair Opening (ALPO) that can be calculated from a dynamic MLC delivery file. We derive an analytic formula for a fractional average fluence error resulting from a systematic gap error of Δ$\chi$ and show that it is inversely proportional to ALPO; explicitly it is equal to, (equation omitted) in which $\varepsilon$ is generally of the order of 1 mm and Δx=2ㆍΔRFO+CMO. This analytic relationship is verified with independent numerical calculations.