• Journal of Korean Society of Water and Wastewater
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• v.29 no.3
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• pp.293-303
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• 2015

Optimal design of the water supply pipe network aims to minimize construction cost while satisfying the required hydraulic constraints such as the minimum and maximum pressures, and velocity. Since considering one single design factor (i.e., cost) is very vulnerable for including future conditions and cannot satisfy operator's needs, various design factors should be considered. Hence, this study presents three kinds of design factors (i.e., minimizing construction cost, maximizing reliability, and surplus head) to perform multi-objective optimization design. Harmony Search (HS) Algorithm is used as an optimization technique. As well-known benchmark networks, Hanoi network and Gyeonggi-do P city real world network are used to verify the applicability of the proposed model. In addition, the proposed multi-objective model is also applied to a real water distribution networks and the optimization results were statistically analyzed. The results of the optimal design for the benchmark and real networks indicated much better performance compared to those of existing designs and the other approach (i.e., Genetic Algorithm) in terms of cost and reliability, cost, and surplus head. As a result, this study is expected to contribute for the efficient design of water distribution networks.

• Journal of Korea Water Resources Association
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• v.55 no.1
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• pp.59-70
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• 2022

Water distribution systems (WDSs) are a representative infrastructure injecting chlorine to disinfect the pathogenic microorganisms and supplying water from sources to consumers. Also, WDSs prescribe to maintain the usual standard (0.1-4.0 mg/L) of residual chlorine. However, the user's usage pattern, water age, network shape, and type affect the hydraulic features (i.e. nodal pressure, pipe velocity) and water quality features (i.e., the residual chlorine concentration). Therefore, this study developed an optimization approach for optimizing WDSs considering water quality-hydraulic factors using Multi-objective Harmony Search (MOHS). The design cost and the system resilience were applied as the design objective functions, and the nodal pressure and the concentration of residual chlorine are used as constraints. The derived optimal designs through this approach were analyzed according to network characteristics such as the network shapes and type. These optimal designs can meet the safety of economic and water quality aspects to increase user acceptance.

• Proceedings of the Korea Water Resources Association Conference
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• 2019.05a
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• pp.161-161
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• 2019

Water security issues, stimulated by increasing population and changing climate, are growing and pausing major challenges for water resources managers around the world. Proper utilization, management and distribution of all available water resources is key to sustainable development for achieving water security To alleviate the water shortage, most of the current research on multi-sources combined water supplies depends on an overall generalization of regional water supply systems, which are seldom broken down into the detail required to address specific research objectives. This paper proposes the concept of optimization framework on multi water sources selection. A multi-objective water allocation model with four objective functions is introduced in this paper. Harmony search algorithm is employed to solve the applied model. The objective functions addresses the economic, environmental, and social factors that must be considered for achieving a sustainable water allocation to solve the issue of water security.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.209-209
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• 2015

상수도 관망은 대표적인 사회기반시설로 수원으로부터 수용가에 이르기까지 안정적으로 유량을 공급하는 것을 목표로 한다. 상수도 관망의 최적설계는 요구되는 절점의 수압, 관로의 유속 등 수리학적 제약조건을 만족시키는 범위 안에서 비용을 최소화하는 설계안을 얻어내는 것을 목표로 시작하였다. 하지만 비용만을 고려한 과거의 상수도 관망 최적설계는 미래의 불확실한 조건에 매우 취약하고, 사용자의 다양한 요구를 충족시키지 못한다. 이 때문에 현대의 상수도 관망의 설계시 다양한 설계인자의 고려와 함께 효율적인 최적설계기법 적용의 필요성이 대두되고 있다. 따라서 본 연구에서는 상수도 관망 최적설계에 다양한 설계인자를 동시에 고려하기 위해 다목적 최적 설계기법인 Multi-objective Harmony Search 알고리즘을 적용하였다. 또한 다목적 최적설계의 효율성 증대를 위하여 매개변수 자동보정 기법 중 하나인 Parameter-Setting-Free (PSF) 기법(Geem and Sim, 2010)을 사용하였다. PSF 기법은 최적화 알고리즘의 매개변수 설정의 번거로움을 없애고, 반복수행을 통한 해 탐색이 진행됨에 따라 가장 효율적으로 작용하는 매개변수를 자동으로 설정하여 탐색효율을 강화하도록 고안된 기법이다. 본 연구에서는 제안된 기법을 실제 상수도관망의 최적설계에 적용하였고 그 결과를 분석하였다. 그 결과 제안된 기법을 통해 관망의 비용을 포함한 다양한 설계인자를 동시에 만족시키는 최적설계안을 효과적으로 도출 할 수 있었으며, 매개변수 자동보정 기법의 적용을 통해 해 탐색의 효율성과 편의성을 향상시킬 수 있었다.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.490-490
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• 2021

상수도 관망은 대표적인 사회기반시설로 수원으로부터 수용가에게 수질적으로 안전한 물을 안정하게 공급하는 것을 목표로 한다. 초기의 상수도 관망의 최적 설계는 비용만을 고려함으로써 미래의 불확실한 상황에 대한 대처가 매우 취약하고, 사용자의 다양한 요구를 충족시키지 못하였다. 또한, 유량과 안정적인 수질 공급을 고려하는 설계는 몇몇 비선형적 요소를 포함하고 있으며, 특히 사용자의 수요 패턴에 따른 잔류 염소 농도가 설계 기준에 부합하지 못하는 문제가 되는 경우 사용자의 심미적, 심리적 불편을 초래할 수 있다. 이는, 수질의 안전성과 직결되는 문제이다. 따라서 본 연구에서는 상수도 관망의 설계에 대하여 수질과 수리학적 특성을 고려한 상수도 관망 다목적 최적 설계를 수행하였다. 상수도 관망은 수질적인 측면을 고려하기 위해 수원에서 수용가까지 용수를 공급하는 과정에서 병원성 미생물을 소독하기 위하여 염소를 주입한다. 또한, 유리 잔류 염소의 평상시 기준을 (1.0-4.0mg/L) 유지하도록 규정하였다 (수도법 시행규칙 제22조의2). 하지만 사용자의 사용패턴, 체류 시간에 따라 잔류염소량이 달라진다. 따라서, 본 연구에서는 상수도 관망의 설계 비용과 염소 주입량을 동시에 설계 인자로서 고려하기 위해 Multi-objective Harmony Search를 적용하고, 그 결과를 분석하였다. 이러한 상수도 관망의 수질 인자와 설계 비용을 고려한 최적 설계안은 경제적 측면 뿐만 아니라 사용자의 수질 측면의 안전성을 충족하는 방안을 제시할 수 있다.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.425-425
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• 2023

상수도시스템의 지속가능한 운영을 위해서는 에너지를 효율적으로 활용하는 것이 필수적이다. 따라서, 본 연구에서는 상수도시스템에서 고압구간의 압력조절을 통해 에너지 측면의 최적 운영기법을 제안하였다. 제안된 최적 운영기법은 마이크로 터빈을 이용하여 에너지 회수를 통한 압력저하와 이로 인한 누수량 저감을 동시에 고려하였다. 본 연구에서 사용한 최적화기법으로는 Multi-objective harmony search 알고리즘을 사용하였으며, 상수도 시스템에서 마이크로 터빈을 모의하기 위해서 EPANET의 압력조절 밸브 (Pressure reduction valve)를 활용하여 압력강하에 따른 에너지 회수를 고려하였다. 제안된 최적운영 기법을 검증하기 위해 Benchmark networks (e.g., 5-nodes network, 25-nodes network)을 적용하였으며, 본 연구를 통해 마이크로 터빈의 최적 규모와 설치위치, 개수를 결정할 수 있으며, 이에 따른 에너지 회수와 누수감소 측면에서 상수도시스템의 지속가능한 운영에 효과적으로 이용될 수 있을 거라 기대된다.

• Steel and Composite Structures
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• v.51 no.6
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• pp.647-659
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• 2024

Given the increased interest in enhancing structural sustainability, the current study sought to apply multiobjective optimization to a footbridge with a steel-concrete composite I-girder structure. It was considered as objectives minimizing the cost for building the structure, the environmental impact assessed by CO2 emissions, and the vertical accelerations created by human-induced vibrations, with the goal of ensuring pedestrian comfort. Spans ranging from 15 to 25 meters were investigated. The resistance of the slab's concrete, the thickness of the slab, the dimensions of the welded steel I-profile, and the composite beam interaction degree were all evaluated as design variables. The optimization problem was handled using the Multiobjective Harmony Search (MOHS) metaheuristic algorithm. The optimization results were used to generate a Pareto front for each span, allowing us to assess the correlations between different objectives. By evaluating the values of design variables in relation to different levels of pedestrian comfort, it was identified optimal values that can be employed as a starting point in predimensioning of the type of structure analyzed. Based on the findings analysis, it is possible to highlight the relationship between the structure's cost and CO2 emission objectives, indicating that cost-effective solutions are also environmentally efficient. Pedestrian comfort improvement is especially feasible in smaller spans and from a medium to a maximum level of comfort, but it becomes expensive for larger spans or for increasing comfort from minimum to medium level.

• Journal of Acupuncture Research
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• v.21 no.4
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• pp.177-196
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• 2004

Objective : Rheumatoid arthritis is an autoimmune disease that pathogenesis is not fully understood and one of the most intractable musculoskeletal diseases. The concern in the immunopathogenesis of rheumatoid arthritis has been increased since 1980's and many immunotherapeutic agents including disease-modifying antirheumatic drugs (DMARDs) were developed and became the mainstay of treatment of rheumatoid arthritis. However, the cure of the disease has hardly been achieved. In oriental medicine, rheumatoid arthritis is related to Bi-Zheng(痺證), that presents pain, swelling, andlor loss of joint function as major clinical manifestations, and also known to be deeply involved in suppression of immune function related to weakness of Jung-Ki(正氣). The herbal medicine, empirically used, could be a potential resource of development of new immunotherapeutic agents for rheumatoid arthritis. Methods : We developed a search strategy using terms to include "rheumatoid arthritis and herbal medicine" combined with "Chinese medicine" and/or "Oriental medicine". The search was focused on experimental studies of herbal medicine (January 1999 to May 2004), which is known to have effects on immune function of patients with rheumatoid arthritis. Computerized search used Internet databases including KISS and RISS4U (Korea), CNKI (China), MOMJ (Main Oriental Medicine Journal, Japan), and PubMed. The articles were selected from journals of universities or major research institutes. Results : The literature search for experimental studies on effects of herbal medicine on immunity of rheumatoid arthritis retrieved a total of 21 articles (Korea; 8, China ; 12, Japan ; 1). Of 21 articles, 10 were related to single-drug formula, 2 to drug interaction, and 9 to multi-drug formula. Single-drug formula was mainly used for aqua-acupuncture and researches on active components. Studies of drug interaction emphasized harmony of Ki-Hyul(氣血) and balance of Han-Yeul(寒熱). Multi-drug regimen was mainly found among formulas for Bo-Ki-Hyul(補氣血) and Bo-Sin(補腎). Conclusion : Studies on rheumatoid arthritis were performed both in vitro and in vivo in vitro study, LPS-stimulated splenocytes and synoviocytes were treated with herbal medicine, resulting in proliferation and activation of immune cells and suppression of cytokine activities in vivo study CIA animal model demonstrated that herbal medicine decreased antibody production and improved function of immune cells. In cellular and molecular study herbal medicine showed profound effects on the level of mRNA expression of certain cytokines related to immune function. This study revealed that herbal medicine has significant immune modulatory action and could be used for recovery of immune dysfunction of rheumatoid arthritis patients.