• 제목/요약/키워드: Multi-Objective function

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발기부전 환자에서의 홍삼의 효능에 관한 연구 -동남아시아의 다국적 연구 (Effectiveness of Korea Red Ginseng in Erectile Dysfunction-Multi-National Approach)

  • 최형기;최영득
    • Journal of Ginseng Research
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    • 제23권4호
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    • pp.247-256
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    • 1999
  • Ginseng has been used in maintaining physical vitality throughout the far-eastern countries and recently its metabolism and actions on neurologic, cardiovascular, and endocrinologic systems are studied. Korean red ginseng (KRG) has been used in various ailments, and to prove its efficacy for erectile dysfunction an international study on Asians other than Korean was performed. Patients with borderline organic and psychogenic erectile dysfunction were included. KRG were given daily, and placebo were given as controls. Treatment lasted a total of 3 months. Surveys including libido, erection, ejaculation, sexual activity, and sexual satisfaction were given. Serum testosterone and erectile function study were taken. Among the 64 patients, 37 patients were followed with KRG. Five had diabetes, 5 hypertension, 5 hypercholesterolemia, 6 low testosterone, 6 psychogenic, and 11 idiopathic. The improvement after KRG administration was $70.2\%$ on objective questionnaire and $75.7\%$ on subjective analysis. When KRG were given, all parameters surveyed have shown improvements compared to the placebo. The effects of KRG in Chinese and Singapores were similar to the Koreans. Serum testosterone levels were nonnalized in 6 patients with KRG, who's serum testosterone levels were reduced from pre-study. Two patient reported constipation, and 2 gastric upsets in the KRG group. In conclusion, KRG has beneficiary action on male erectile capabilities with little side effects. KRG is effective in Koreans and also Asians. The exact action mechanism and the active ingredients in KRG need to be studied.

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Clincal Efficacy of Korean Red Ginseng for Erectile Dysfunction -Multi-national Approach

  • Choi, Hyung-Ki;Choi, Young-Deuk;Lee, Woong-Hee
    • 고려인삼학회:학술대회논문집
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    • 고려인삼학회 1998년도 Advances in Ginseng Research - Proceedings of the 7th International Symposium on Ginseng -
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    • pp.208-215
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    • 1998
  • Ginseng has been used in maintaining physical vitality all over the East Asian countries and recently its metabolism and actions on neurologic, cardiovascular and endocrinologic systems are being elucidated. Korean red ginseng (KRG) has been used in various aliments, and to prove its efficacy icy erectile dysfunction an international study on Asians other than Korean was performed. Patients with borderline organic and psychogenic erectile dysfunction were included. KRG were given daily, and placebos were given as controls. Treatment lasted a total of 3 months. Surveys including libido, erectile potency, the sexual satisfactions were given. Serum testosterone and erectile function study were taken. Among the 23 patients with KRG, 18 patients were followed. Four had diabetes, 2 hypertension, 3 hyperchole, iterolemia, 1 low testosterone,4 psychogenic, and 4 idiopathic. In 10 patients with placebo, 7 were followed for more than three months. The clinical efficacy of KRG was 66.7% on objective Questionnaire and 72.2% on subjective analysis. When KRG were given, all parameters surveyed have shown improvements compared to the controls. Serum testosterone Bevels were normalized in 2 patients with KRG, whose serum testosterone levels were reduced from prestudy. When the erectile functions after audiovisual stimuli evaluated using Rigiscan in 6 patients with KRG,4 showed rigidity move than 70oyc. One patient reported constipation, and 2 gastric up-sets in the KRG group. In conclusion, KRG has beneficiary action on male erectile capabilities with minimal side effects. Thus KRG has been proven effective in Koreans, and a result on other Asians is pending. The exact action mechanism and the active ingredients in KRC need to be itudied.

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PV 시스템의 최적 배치 문제를 위한 이산 PSO에서의 규칙 기반 하이브리드 이산화 (Rule-based Hybrid Discretization of Discrete Particle Swarm Optimization for Optimal PV System Allocation)

  • 송화창;고재환;최병욱
    • 한국지능시스템학회논문지
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    • 제21권6호
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    • pp.792-797
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    • 2011
  • 본 논문은 배전망에서의 PV (photovoltaic) 발전 시스템의 최적 배치 문제를 이산 입자 군집 최적화 (DPSO, discrete particle swarm optimization)를 이용하여 해를 구할 때 DPSO에 포함되어야 하는 이산화 단계를 위한 하이브리드 이산화 기법의 적용에 대하여 논한다. 이를 위해 PSO 반복단계에서 목적 함수 값과 최적화 속도를 입력 파라미터로 하는 규칙 기반 전문가 시스템을 제안하고 이산 변수를 포함하여 표현되는 PV 시스템 배치 문제의 최적해를 구하는데 적용하였다. 다수준 이산화를 위하여 간단한 라운딩과 sigmoid 함수를 이용한 3단계 및 5단계 이산화 기법을 하이브리드 형태로 적용하였다. 규칙 기반 전문가 시스템을 적용하여 각 PSO 과정에서 적절한 이산화 기법을 선택함으로써 기존의 DPSO보다 좋은 성능의 최적화가 가능하도록 하였다.

Optimal Location of FACTS Devices Using Adaptive Particle Swarm Optimization Hybrid with Simulated Annealing

  • Ajami, Ali;Aghajani, Gh.;Pourmahmood, M.
    • Journal of Electrical Engineering and Technology
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    • 제5권2호
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    • pp.179-190
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    • 2010
  • This paper describes a new stochastic heuristic algorithm in engineering problem optimization especially in power system applications. An improved particle swarm optimization (PSO) called adaptive particle swarm optimization (APSO), mixed with simulated annealing (SA), is introduced and referred to as APSO-SA. This algorithm uses a novel PSO algorithm (APSO) to increase the convergence rate and incorporate the ability of SA to avoid being trapped in a local optimum. The APSO-SA algorithm efficiency is verified using some benchmark functions. This paper presents the application of APSO-SA to find the optimal location, type and size of flexible AC transmission system devices. Two types of FACTS devices, the thyristor controlled series capacitor (TCSC) and the static VAR compensator (SVC), are considered. The main objectives of the presented method are increasing the voltage stability index and over load factor, decreasing the cost of investment and total real power losses in the power system. In this regard, two cases are considered: single-type devices (same type of FACTS devices) and multi-type devices (combination of TCSC, SVC). Using the proposed method, the locations, type and sizes of FACTS devices are obtained to reach the optimal objective function. The APSO-SA is used to solve the above non.linear programming optimization problem for better accuracy and fast convergence and its results are compared with results of conventional PSO. The presented method expands the search space, improves performance and accelerates to the speed convergence, in comparison with the conventional PSO algorithm. The optimization results are compared with the standard PSO method. This comparison confirms the efficiency and validity of the proposed method. The proposed approach is examined and tested on IEEE 14 bus systems by MATLAB software. Numerical results demonstrate that the APSO-SA is fast and has a much lower computational cost.

ModelCenter를 이용한 QTP-UAV 프롭로터 블레이드 형상 최적설계 (Design Optimization of QTP-UAV Prop-Rotor Blade Using ModelCenter)

  • 강희정
    • 항공우주시스템공학회지
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    • 제11권4호
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    • pp.36-43
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    • 2017
  • 쿼드틸트 무인기에 적용되는 프롭로터 블레이드 형상 최적설계를 수행하였다. 형상 최적설계 프로세스 통합은 ModelCenter(R) 프로그램을 이용하였으며, 최적설계 과정에서 성능해석은 CAMRAD-II를 사용하였다. 목적함수는 제자리비행 및 전진비행 모드에서 성능효율 최대화로 설정하였으며, 제한조건은 소요 동력 및 피치로드 하중 값이 기본 형상 값보다 작게 되도록 설정하였다. 설계변수로는 블레이드 루트 코드길이, 테이퍼비, 비틀림 각의 기울기 및 각도, 하반각, 끝단 형상 생성을 위한 파라볼릭 계수, 하반각과 끝단형상이 적용되는 블레이드 스팬위치, 블레이드 단면을 구성하는 익형의 위치로 구성하였다. 최적 설계 결과 기준 형상 대비 제자리비행 효율은 1.6%, 전진 비행 효율은 13.6% 향상된 프롭로터 블레이드 형상을 도출할 수 있었으며, 피치로드 하중은 약 30% 감소하였다.

Low pH stress responsive transcriptome of seedling roots in wheat (Triticum aestivum L.)

  • Hu, Haiyan;He, Jie;Zhao, Junjie;Ou, Xingqi;Li, Hongmin;Ru, Zhengang
    • Genes and Genomics
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    • 제40권11호
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    • pp.1199-1211
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    • 2018
  • Soil acidification is one of major problems limiting crop growth and especially becoming increasingly serious in China owing to excessive use of nitrogen fertilizer. Only the STOP1 of Arabidopsis was identified clearly sensitive to proton rhizotoxicity and the molecular mechanism for proton toxicity tolerance of plants is still poorly understood. The main objective of this study was to investigate the transcriptomic change in plants under the low pH stress. The low pH as a single factor was employed to induce the response of the wheat seedling roots. Wheat cDNA microarray was used to identify differentially expressed genes (DEGs). A total of 1057 DEGs were identified, of which 761 genes were up-regulated and 296 were down-regulated. The greater percentage of up-regulated genes involved in developmental processes, immune system processes, multi-organism processes, positive regulation of biological processes and metabolic processes of the biological processes. The more proportion of down-regulation genes belong to the molecular function category including transporter activity, antioxidant activity and molecular transducer activity and to the extracellular region of the cellular components category. Moreover, most genes among 41 genes involved in ion binding, 17 WAKY transcription factor genes and 17 genes related to transport activity were up-regulated. KEGG analysis showed that the jasmonate signal transduction and flavonoid biosynthesis might play important roles in response to the low pH stress in wheat seedling roots. Based on the data, it is can be deduced that WRKY transcription factors might play a critical role in the transcriptional regulation, and the alkalifying of the rhizosphere might be the earliest response process to low pH stress in wheat seedling roots. These results provide a basis to reveal the molecular mechanism of proton toxicity tolerance in plants.

산림시업이 일본잎갈나무 임분의 생장과 직경분포모형에 미치는 영향 (Influences of Forest Management Activity on Growth and Diameter Distribution Models for Larix kaempferi Carriere Stands in South Korea)

  • 이선주;이영진
    • 농업생명과학연구
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    • 제52권6호
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    • pp.37-47
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    • 2018
  • 본 연구의 목적은 전국에 분포하는 일본잎갈나무 임분에 대해 산림시업 수행이 직경분포변화에 미치는 영향에 대해 분석하였다. 본 연구에 사용한 자료는 국가산림자원조사 중 시업지 232plots, 비시업지 47plots의 고정표본점 자료를 활용하였다. 직경분포모델은 Weibull 누적분포함수를 사용하였으며, 분석 방법에는 백분위(Percentile)에 근거한 직경모형추정, 백분위(Percentile)에 대한 모수복구 방법을 사용하였다. 개발한 모델을 이용하여 산림시업의 수행여부에 따른 시나리오(임령, 지위지수, 임분밀도) 별임분생장량을 예측한 결과, 시업지 임분의 최대임목본수를 차지하는 평균 흉고직경의 이동이 비시업지 임분에 비해 이동량과 생장량이 더 높게 나타났으며, 대경목이 차지하는 비율 또한 시업지 임분이 높게 예측되었다. 본 연구의 결과는 직경급에 따른 목재생산량의 장기적인 예측과 동적인 임분구조 해석에 기초적인 정보를 제공할 수 있을 것으로 사료되어진다.

Robotic lower pelvic port placement for optimal upper paraaortic lymph node dissection

  • Paek, Jiheum;Kang, Elizabeth;Lim, Peter C.
    • Journal of Gynecologic Oncology
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    • 제29권6호
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    • pp.87.1-87.4
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    • 2018
  • Objective: Upper paraaortic lymph node dissection (UPALD) to the infrarenal level is one of the most challenging robotic procedures. Because robotic system has the limitation in robotic arm mobility. This surgical video introduces a novel robotic approach, lower pelvic port placement (LP3), to perform optimally and simultaneously both UPALD and pelvic procedures in gynecologic cancer patients using da Vinci Xi system. Methods: The patient presented with high-grade endometrial cancer. She underwent robotic surgical staging operation. For the setup of the LP3, a line was drown between both anterior superior iliac spines. At 3 cm below this line, another line was drown and four robotic ports were placed on this line. Results: After paraaortic lymph node dissection (PALD) was completed, the boom of robotic system was rotated $180^{\circ}$ to retarget for the pelvic lateral displacement. Robotic ports were placed and docked again. The operation was completed robotically without any complication. Conclusion: The LP3 was feasible for performing simultaneously optimal PALD as well as procedures in pelvic cavity in gynecologic cancer patients. The advantage of LP3 technique is the robotic port placement that affords for multi-quadrant surgery, abdominal and pelvic dissection. The LP3 is facilitated by utilizing advanced technology of Xi system, including the patient clearance function, the rotating boom, and 'port hopping' that allows using every ports for a camera. The LP3 will enable surgeons to extend the surgical indication of robotic surgical system in the gynecologic oncologic field.

경혈 교육을 위한 3D 및 증강현실 기술을 활용한 한의학 통합교육 테이블 개발 (A Development of an Acupoints Education Table using 3D Technology and Augmented Reality)

  • 양승정;류창주;김상철;김재석
    • Korean Journal of Acupuncture
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    • 제38권4호
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    • pp.267-274
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    • 2021
  • Objectives : Acupoints education is important in that it can determine the clinical competency of Korean Medicine Doctors (KMDs). Accordingly, we aimed to develop a practical simulator for acupoints education, acupoints training, acupoints practice, and acupoints evaluation. Methods : Korean Medicine (KM) SMART Table can be divided into hardware, server and components, and is organically linked. We develop KM SMART Table that combines the hardware of a human-sized table with a UHD display capable of multi-touch in two cases and software that can teach acupoints. We make Augmented Reality (AR) contents linked with KM SMART Table contents and develop applications that can use contents using mobile devices. By developing an AR image tracking module to react with KM SMART Table, it enables acupoint learning according to the mobile device platform and human anatomy. Results : The current system is a prototype where some 3D technology has been implemented, but the AR function will be produced later. New learning using 3D and AR will be required during acupoints education and acupoints practice. It will be used a lot in OSCE (Objective Structured Clinical Examination) practices for strengthening the competency of KMDs, and it will be of great help not only in KM education as a unique simulator of KM, but also in the practice of acupuncture and chuna for musculoskeletal diseases. Conclusions : The KM SMART Table is a technology that combines 3D and AR to learn acupoints, and to conduct acupoints OSCE practice, and we suggest that it can be usefully used for educational evaluation.

기계적 잠금장치의 적용여부에 따른 덕티드팬 클러치의 최적설계 및 분석 (Optimal Design and Analysis of Ducted Fan Clutch With or Without Mechanical Lock-up)

  • 김수철;김재승;문상곤;이근호
    • 항공우주시스템공학회지
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    • 제17권1호
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    • pp.10-15
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    • 2023
  • 덕티드팬의 동력절환장치인 클러치의 마찰판 사양을 최적설계하고 그 결과를 분석하였다. 클러치는 기계적 잠금장치의 적용 여부에 따라 2가지 방식으로 구분하고 각자의 설계 조건 하에 최적화 되었다. 클러치를 최적 설계하기 위한 인자로 전달토크 용량, 마찰재 면압, 마찰면의 온도 및 드래그 토크 등을 계산하였고, 클러치 분리판의 부피와 드래그 토크의 최소화를 최적설계의 목적함수로 활용하였다. 기계적 잠금장치가 포함되지 않은 Type 1의 경우 덕티드팬의 피치각에 상관없이 클러치의 작동이 가능하지만, 기계적 잠금장치가 포함된 Type 2에 비해 마찰면의 외경이 약 2배정도 증가하였고, 부피는 약 5~7배, 드래그 토크는 약 7~12배 정도 증가하였다.