• Title/Summary/Keyword: Multi-Cell Model

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A Multi-scale Simulation Model of Circulation Combining Cardiovascular Hemodynamics with Cardiac Cell Mechanism (심근세포-심혈관계 혈류역학이 결합된 복합적 순환계 모델에 관한 연구)

  • Ko Hyung Jong;Leem Chae Hun;Shim Eun Bo
    • Journal of Institute of Control, Robotics and Systems
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    • v.10 no.12
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    • pp.1164-1171
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    • 2004
  • A new multi-scale simulation model is proposed to analyze heart mechanics. Electrophysiology of a cardiac cell is numerically approximated using the previous model of human ventricular myocyte. The ion transports across cell membrane initiated by action potential induce an excitation-contraction mechanism in the cell via cross bridge dynamics. Negroni and Lascano model (NL model) is employed to calculate the tension of cross bridge which is closely related to the ion dynamics in cytoplasm. To convert the tension on cell level into contraction force of cardiac muscle, we introduce a simple geometric model of ventricle with a thin-walled hemispheric shape. It is assumed that cardiac tissue is composed of a set of cardiac myocytes and its orientation on the hemispheric surface of ventricle remains constant everywhere in the domain. Application of Laplace law to the ventricle model enables us to determine the ventricular pressure that induces blood circulation in a body. A lumped parameter model with 7 compartments is utilized to describe the systemic circulation interacting with the cardiac cell mechanism via NL model and Laplace law. Numerical simulation shows that the ion transports in cell level eventually generate blood hemodynamics on system level via cross bridge dynamics and Laplace law. Computational results using the present multi-scale model are well compared with the existing ones. Especially it is shown that the typical characteristics of heart mechanics, such as pressure volume relation, stroke volume and ejection fraction, can be generated by the present multi-scale cardiovascular model, covering from cardiac cells to circulation system.

A 3-cell CCI(Cell-to-Cell Interference) model and error correction algorithm for Multi-level cell NAND Flash Memories (다중셀 낸드 플래시 메모리의 3셀 CCI 모델과 이를 이용한 에러 정정 알고리듬)

  • Jung, Jin-Ho;Kim, Shi-Ho
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.48 no.10
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    • pp.25-32
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    • 2011
  • We have analyzed adjacent cell dependency of threshold voltage shift caused by the cell to cell interference, and we proposed a 3-adjacent-cell model to model the pattern dependency of the threshold voltage shift. The proposed algorithm is verified by using MATLAB simulation and measurement results. In the experimental results, we found that accuracy of the proposed simple 3-adjacient-cell model is comparable to the widely used conventional 8-adjacient-cell model. The Bit Error Rate (BER) of LSB and of MSB is improved by 28.9% and 19.8%, respectively, by applying the proposed algorithm based on 3-adjacent-cell model to 20nm-class 2-bit MLC NAND flash memories.

A 3D FEA Model with Plastic Shots for Evaluation of Peening Residual Stress due to Multi-Impacts (다중충돌 피닝잔류응력 평가를 위한 소성숏이 포함된 3차원 유한요소해석 모델)

  • Kim, Tae-Hyung;Lee, Hyungy-Il
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.32 no.8
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    • pp.642-653
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    • 2008
  • In this paper, we propose a 3-D finite element (FE) analysis model with combined physical behavior and kinematical impact factors for evaluation of residual stress in multi-impact shot peening. The FE model considers both physical behavior of material and characteristics of kinematical impact. The physical parameters include elastic-plastic FE modeling of shot ball, material damping coefficient, dynamic friction coefficient. The kinematical parameters include impact velocity and diameter of shot ball. Multi-impact FE model consists of 3-D symmetry-cell. We can describe a certain repeated area of peened specimen under equibiaxial residual stress by the cell. With the cell model, we investigate the FE peening coverage, dependency on the impact sequence, effect of repeated cycle. The proposed FE model provides converged and unique solution of surface stress, maximum compressive residual stress and deformation depth at four impact positions. Further, in contrast to the rigid and elastic shots, plastically deformable shot produces residual stresses closer to experimental solutions by X-ray diffraction. Consequently, it is confirmed that the FE model with peening factors and plastic shot is valid for multi-shot peening analyses.

Nonlinear viscous material model

  • Ivica Kozar;Ivana Ban;Ivan Zambon
    • Coupled systems mechanics
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    • v.12 no.5
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    • pp.419-428
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    • 2023
  • We have developed a model for estimating the parameters of viscous materials from indirect tensile tests for asphalt. This is a simple Burger nonlinear rheological two-cell model or standard model. At the same time, we begin to develop a more versatile and complex multi-cell model. The simple model is validated using experimental load-displacement results from laboratory tests: The recorded displacements are used as input values and the measured force data are simulated with the model. The optimal model parameters are estimated using the Levenberg-Marquardt method and a very good agreement between the experimental results and the model calculations is shown. However, not all parts of the model are active in the loading phase of the experiment, so we extended the validation of the model to the simulation of the relaxation behaviour. In this stage, the other model parameters are activated and the simulation results are consistent with the literature. At this stage, we have estimated the parameters only for the two-cell uniaxial model, but further work will include results for the multi-cell model.

Dynamic Characteristics of Composite Thin-Walled Beams with a Chord-Wise Asymmetric Cross-Section: II. Multi-Cell (시위 방향 비대칭 단면의 복합재료 박벽보의 동특성 연구: II. 다중-셀)

  • Kim, Keun-Taek
    • Journal of Aerospace System Engineering
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    • v.13 no.2
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    • pp.51-59
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    • 2019
  • Subsequently, Part I [1], which was about the single-cell model, a composite thin-walled beam with a multi-cell of chord-wise asymmetric cross-section, was selected in this study. Moreover, the theoretical dynamic characteristics of the model were analyzed. For this analysis, mathematical modeling was performed by considering the warping restraint effects, transverse shear effects, taper ratio and cross-section ratio. Similar to part I, the mass, stiffness coefficients and Eigen frequencies of the multi-cell section considered were investigated. In particular, the comparison between the multi-cell and single-cell sections and the effects of the cross-section ratio and taper ratio of the model on the Eigen frequencies were analyzed. However, the results compared when the asymmetry of the section was considered and warping function were not corrected.

Simulation Model of Membrane Gas Separator Using Aspen Custom Modeler (ACM을 이용한 가스 투과막 특성 해석 모델)

  • Song, Dong-keun;Shin, Gahui;Yun, Jinwon;Yu, Sangseok
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.40 no.12
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    • pp.761-768
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    • 2016
  • Membranes are used to separate pure gas from gas mixtures. In this study, three different types of mass transport through a membrane were developed in order to investigate the gas separation capabilities of a membrane. The three different models typically used are a lumped model, a multi-cell model, and a discretization model. Despite the multi-cell model producing similar results to a discretization model, the discretization model was selected for this investigation, due to the cell number dependence of a multi-cell model. The mass transport model was then used to investigate the effects of pressure difference, flow rate, total exposed area, and permeability. The results showed that the pressure difference increased with the stage cut, but the selectivity was a trade-off for the increasing pressure difference. Additionally, even though permeability is an important parameter, the selectivity and stage cut of the membrane converged as permeability increased.

Computational analysis of heart mechanics using a cell-autonomic nerve control-hemodynamic system coupled model (세포-신경계-혈류역학 시스템 통합모델에 의한 심장역학 분석)

  • Jun, Hyung-Min;Shim, Eun-Bo
    • Proceedings of the KSME Conference
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    • 2007.05b
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    • pp.2941-2946
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    • 2007
  • A model of the cardiovascular system coupling cell, hemodynamics and autonomic nervecontrol function is proposed for analyzing heart mechanics. We developed a comprehensive cardiovascular model with multi-physics and multi-scale characteristics that simulates the physiological events from membrane excitation of a cardiac cell to contraction of the human heart and systemic blood circulation and ultimately to autonomic nerve control. Using this model, we delineatedthe cellular mechanism of heart contractility mediated by nerve control function. To verify the integrated method, we simulated a 10% hemorrhage, which involves cardiac cell mechanics, circulatory hemodynamics, and nerve control function. The computed and experimental results were compared. Using this methodology, the state of cardiac contractility, influenced by diverse properties such as the afterload and nerve control systems, is easily assessed in an integrated manner.

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Operation-sequence-based Approach for Designing a U-shaped Independent-Cell System with Machine Requirement Incorporated (설비능력과 작업순서를 고려한 U-라인상에서의 셀 시스템 설계)

  • 박연기;성창섭;정병호
    • Journal of the Korean Operations Research and Management Science Society
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    • v.26 no.1
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    • pp.71-85
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    • 2001
  • This paper considers a cost model for a U-shaped manufacturing cell formation which incorporates a required number of machines and various material flows together under multi-part multi-cell environment. The model is required to satisfy both the specified operation sequence of each part and the total part demand volume, which are considered to derive material handling cost in U-shaped flow line cells. In the model several cost-incurring factors including set-up for batch change-over, processing time for operations of each part, and machine failures are also considered in association with processing load and capacity of each cell. Moreover, a heuristic for a good machine layout in each cell is newly proposed based on the material handling cost of each alternative sequence layout. These all are put together to present an efficient heuristic for the U-shaped independent-cell formation problem, numerical problems are solved to illustrate the algorithm.

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Torsion strength of single-box multi-cell concrete box girder subjected to combined action of shear and torsion

  • Wang, Qian;Qiu, Wenliang;Zhang, Zhe
    • Structural Engineering and Mechanics
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    • v.55 no.5
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    • pp.953-964
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    • 2015
  • A model has been proposed that can predict the ultimate torsional strength of single-box multi-cell reinforced concrete box girder under combined loading of bending, shear and torsion. Compared with the single-cell box girder, this model takes the influence of inner webs on the distribution of shear flow into account. According to the softening truss theory and thin walled tube theory, a failure criterion is presented and a ultimate torsional strength calculating procedure is established for single-box multi-cell reinforced concrete box girder under combined actions, which considers the effect of tensile stress among the concrete cracks, Mohr stress compatibility and the softened constitutive law of concrete. In this paper the computer program is also compiled to speed up the calculation. The model has been validated by comparing the predicted and experimental members loaded under torsion combined with different ratios of bending and shear. The theoretical torsional strength was in good agreement with the experimental results.

Multi-physics Unit Model of Fuel cell for Railway Vehicle Propulsion Systems

  • Abbas, Mazhar;Cho, Inho;Kim, Jonghoon
    • Proceedings of the KIPE Conference
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    • 2018.07a
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    • pp.356-357
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    • 2018
  • Fuel-cell powered Railway Vehicle Propulsion Systems (RVPSs) are highly desirable due to environment friendly characteristics, and high efficiency of fuel cell (FC). Among various types, the faster start-up and optimality to frequent starts and stops of Polymer electrolyte membrane fuel cell (PEMFC) makes it well suited for propulsion systems. A comprehensive model of PEMFC with reflection of multi-physics behavior required to identify and validate its performance in real RVPSs. Thus this paper will model and simulate the PEMFC unit cell model: a detailed reflection of governing laws and account of dynamic conditions.

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