• Title/Summary/Keyword: Multi strategies

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Gene Expression Profiling in Hepatic Tissue of two Pig Breeds

  • Jang, Gul-Won;Lee, Kyung-Tai;Park, Jong Eun;Kim, Heebal;Kim, Tae-Hun;Choi, Bong-Hwan;Kim, Myung Jick;Lim, Dajeong
    • Journal of Animal Science and Technology
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    • v.54 no.6
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    • pp.383-394
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    • 2012
  • Microarray analyses provide information that can be used to enhance the efficiency of livestock production. For example, microarray profiling can potentially identify the biological processes responsible for the phenotypic characteristics of porcine liver. We performed transcriptome profiling to identify differentially expressed genes (DEGs) in liver of pigs from two breeds, the Korean native pigs (KNP) and Yorkshire pigs. We correctly identified expected DEGs using factor analysis for robust microarray summarization (FARMS) and robust multi-array average (RMA) strategies. We identified 366 DEGs in liver (p<0.05, fold-change>2). We also performed functional analyses, including gene ontology and molecular network analyses. In addition, we identified the regulatory relationship between DEGs and their transcription factors using in silico and qRT-PCR analysis. Our findings suggest that DEGs and their transcription factors may have a potential role in adipogenesis and/or lipid deposition in liver tissues of two pig breeds.

Environmental Impact Assessments along with Construction of Residential and Commercial Complex (주거단지 건설이 하천에 미치는 생태영향평가)

  • An, Kwang-Guk;Han, Jeong-Ho;Lee, Jae Hoon
    • Journal of Environmental Impact Assessment
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    • v.21 no.5
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    • pp.631-648
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    • 2012
  • The integrative ecological approaches of chemical assessments, physical habitat modelling, and multi-metric biological health modelling were applied to Gwanpyeong Stream within Gap-Stream watersheds to evaluate environmental impacts on the constructions of residential and commercial complex. For the analysis, the surveys conducted from 45 sites of reference streams within the Gap-Stream watershed and 3 regular sites during 2009 - 2010. Physical habitat health, based on the habitat model of Qualitative Habitat Evaluation Index(QHEI) declined from the headwaters(good - fair condition) to the downstream(poor condition). Chemical water quality, based turbidity and electric conductivity(EC), was degraded toward to the downstream, and especially showed abrupt increases, compared to the values of control streams(CS). Also, concentrations of chlorophyll-a in the downstreams were greater compared to the control stream(CS), indicating an eutrophication. Biological health conditions, based on the Index of Biological Integrity(IBI) using fish assemblages, averaged 19.3 which is judged as a fair condition by the biological criteria of the Ministry of Environment, Korea. The comparisons of model metric values in sensitive species and riffle-benthic species on the Maximum Species Richness Line(MSRL) of 45 reference streams indicated a massive disturbances in all sampling locations. Also, tolerance guild and trophic guild analyses suggest that dominances of tolerant species and omnivores were evident, indicating a biological degradation by habitat disturbances and organic matter pollutions. There was no distinct longitudinal variations of IBI model values from the headwater to the downstream in spite of slight chemical and habitat health gradients among the sampling sites. Overall, integrative ecological health(IEH) scores, based on the chemical, physical, and biological parameters, were low compared to the 45 reference streams due to physical and chemical disturbances of massive constructions of the residential and commercial complex. This stream, thus showed a tendency of typical urban streams which are disturbed in the chemical water quality, habitat structures, and biological integrity. Effective stream management plans and restoration strategies are required in this urban stream for improving integrative stream health.

A Study on Gamers Segmentation based upon Uses and Gratifications of Mobile games (모바일게임 이용 충족이론을 기반으로 한 모바일 게이머 유형 분석에 관한 연구)

  • Han, Kwang-Hyun;Kim, Tae-Ung
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2005.10a
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    • pp.133-164
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    • 2005
  • Mobile games have emerged as the most innovative entertainment technology, adding new revenue streams, taking advantage of the potential of wireless applications and service offerings. Mobile games, like any other types of computer game, offer a unique value for users in providing an exciting digital experience in virtual worlds. Players can become empowered through the development of new characters and strategies within games to achieve rewarding successes against the computers and other players. The overall trend for mobile games is towards bigger, more colorful, more involving and exciting contents, which will build upon the developing capabilities of mobile phones and networks in order to bring new styles, concepts and experiences of game play to the users. In this paper, we attempt to investigate the demographic factors which play critical roles in determining the level of playing times; classify mobile gamers based on their motives for playing games; and empirically test differences in their demographic factors and mobile game usage. Statistical results show that significant differences in playing times exist, depending upon their age, gender, mobile device, mobile phone usage, mobile game experiences, and preferred games genres. Applying Factor analysis, we have identified Escape, Social interaction, Challenge and Competition, Fantasy, Diversion and Relaxation, Ease of Accessibility as key motivators for playing mobile games. Additional cluster analysis shows that the categorization of gamers, according to their usage habits and the key motivators for playing, can be made as follows: M-gamers, Multi-gamers and Communication-focused gamers. Further correlation of these grouping with socio-economic data shows the significant differences in gaming habits and patterns of mobile phone use.

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Nonlinear stochastic optimal control strategy of hysteretic structures

  • Li, Jie;Peng, Yong-Bo;Chen, Jian-Bing
    • Structural Engineering and Mechanics
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    • v.38 no.1
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    • pp.39-63
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    • 2011
  • Referring to the formulation of physical stochastic optimal control of structures and the scheme of optimal polynomial control, a nonlinear stochastic optimal control strategy is developed for a class of structural systems with hysteretic behaviors in the present paper. This control strategy provides an amenable approach to the classical stochastic optimal control strategies, bypasses the dilemma involved in It$\hat{o}$-type stochastic differential equations and is applicable to the dynamical systems driven by practical non-stationary and non-white random excitations, such as earthquake ground motions, strong winds and sea waves. The newly developed generalized optimal control policy is integrated in the nonlinear stochastic optimal control scheme so as to logically distribute the controllers and design their parameters associated with control gains. For illustrative purposes, the stochastic optimal controls of two base-excited multi-degree-of-freedom structural systems with hysteretic behavior in Clough bilinear model and Bouc-Wen differential model, respectively, are investigated. Numerical results reveal that a linear control with the 1st-order controller suffices even for the hysteretic structural systems when a control criterion in exceedance probability performance function for designing the weighting matrices is employed. This is practically meaningful due to the nonlinear controllers which may be associated with dynamical instabilities being saved. It is also noted that using the generalized optimal control policy, the maximum control effectiveness with the few number of control devices can be achieved, allowing for a desirable structural performance. It is remarked, meanwhile, that the response process and energy-dissipation behavior of the hysteretic structures are controlled to a certain extent.

Quality of Life among Breast Cancer Patients Undergoing Treatment in National Cancer Centers in Nepal

  • Manandhar, Sajani;Shrestha, Deepak Sundar;Taechaboonsermsk, Pimsurang;Siri, Sukhontha;Suparp, Jarueyporn
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9753-9757
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    • 2014
  • Purpose: To study the quality of life and to identify associated factors among breast cancer patients undergoing treatment in national cancer centers in Nepal. Materials and Methods: One hundred breast cancer patients were selected and interviewed using a structured questionnaire. European Organization of Research and Treatment of Cancer EORTC-QLQ-C30 and EORTC-QLQ-BR23 were used to assess quality of life and modified Medical Outcome Study -Social Support survey(mMOS-SS) was used to assess social support. Only multi-item scales of EORTC C30 and BR23 were analyzed for relationships. Independent sample T-tests and ANOVA were applied to analyze differences in mean scores. Results: The score of global health status/quality of life (GHS/GQoL) was marginally above average (mean=52.8). The worst performed scales in C-30 were emotional and social function while best performed scales were physical and role function. In BR-23, most of the patients fell into the problematic group regarding sexual function and enjoyment. Almost 90% had financial difficulties. Symptom scales did not demonstrate many problems. Older individuals, patients with stage I breast cancer and thosewith good social support were found to have good GHS/GQoL. Of all the influencing factors, social support was established to have strong statistical associations with most of the functional scales: GHS/GQoL (0.003), emotional function (<0.001), cognitive function (0.020), social function (<0.001) and body image function (0.011). Body image was significantly associated with most of the influencing factors: monthly family income (0.003), type of treatment (<0.001), type of surgery (<0.001), stage of cancer (0.017) and social support (0.011). Conclusions: Strategies to improve social support of the patients undergoing treatment should be given priority and financial difficulties faced by breast cancer patients should be well addressed from a policy making level by initiating health financing system.

A Exploratory Study on the Efficient Strategies for Cross-Cultural in the Hospitality Industry (환대산업의 다문화주의 교류에 따른 효율적인 경영전략에 관한 탐색적 연구)

  • Lee Sang-Mi
    • The Journal of the Korea Contents Association
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    • v.5 no.3
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    • pp.151-157
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    • 2005
  • There are successful multinationals like McDonald's, and International hotel chain. The reason is efficiency managing diversity workforces. Therefore, purpose of this study suggests practical guidelines to handling global workforce for creative ideas, diversity for network, and pool for superiority workforces. 1. The company or university we provided by training program for cross-culture seminar, and education program for global culture & manner. 2 The employees express their perceptions and feelings in their own language, the discussions were videotaped, and used for decreasing misfactors such as misperceptions, misevaluations, and mistrust. 3. It builds up various program for understanding cultural difference like seminar, world business manner, and costume & food culture for each country. 4. Top manager should keep in mind that cross-culture has diversity and consistency at the same time.

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Packet Scheduling Scheme and Receiver-Based Recovery Scheme for MPTCP in Heterogeneous Networks (이종망에서 MPTCP를 위한 패킷 스케줄링 방법과 수신단 기반의 손실 복구 방법)

  • Oh, Bong-Hwan;Kim, Hanah;Lee, Jaiyong
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37B no.11
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    • pp.975-983
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    • 2012
  • Multi network interface has become common phenomenon for mobile devices such as smart phone which has 3G, LTE-advanced, WiFi. Consequently, there are researches for a transmission strategies using multiple paths below on end-to-end connection. MPTCP which is proposed and being standardized by the IETF as a new transport protocol can perform concurrent multipath transfer using multiple network interfaces. However, current MPTCP has performance degradation when it use heterogeneous networks which have quite different network characteristics. Therefore, this paper proposes the packet scheduling scheme and receiver-based recovery scheme to reduce the performance degradation due to reordering problem. Also, simulation results show that the proposed scheme can improve throughput and retransmission performance.

Factors Impacting the Physical Function of Older Adults in Korean Long-Term Care Hospitals

  • Lee, Ji-Yun;Kim, Eun-Young;Cho, Eun-Hee
    • Journal of Korean Academy of Nursing
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    • v.41 no.6
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    • pp.780-787
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    • 2011
  • Purpose: This study was conducted to examine activities of daily living (ADL) of older adults admitted to Korean long-term care hospitals (LTCHs), and to explore the patient and organizational factors that have an impact on the ADL of this population. Methods: A secondary analysis of the Korean minimum data set (K-MDS) of patients (N=14,369) and of the profiles of LTCHs (N=358) from the Health Insurance Review and Assessment Service was done between January and July 2008. The outcome variable was ADL score 6 months after baseline assessment. Multi-level linear regression was employed to explore the patient and organizational factors that affected ADL scores. Results: Of the patients, 45.4% had a baseline ADL score of between 31 and 40, with a score of 40 indicating that the patient was entirely dependent for all items. None of the organizational characteristics were significantly associated with effects on the ADLs of older adults who had been in a LTHC for at least 6 months. However, patient characteristics, such as age, baseline ADL, frequency of physical therapy, urinary incontinence, fecal incontinence, pressure ulcers, and having a tube or catheter, were significantly associated with ADL 6 months after baseline. Conclusion: In order to maintain and improve the ADL of older adults in LTCHs, we should develop strategies to prevent urinary and fecal incontinence, pressure ulcers, unnecessary tubes or catheters, providing adequate physical therapy. Additional studies should include more detailed information regarding nursing staff, including RN hours for direct care, education level and turnover.

The Effect of Bundle Framing on Purchase Intention (묶음제품 프레이밍이 구매의사 결정에 미치는 영향)

  • Lee, So-Young;Kim, Hyang-Mi
    • Journal of Digital Convergence
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    • v.12 no.12
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    • pp.233-241
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    • 2014
  • This study explore how framing affects the consumer's attitude toward the bundle products. On the basis of the framing theory, response compatibility hypothesis and regulatory focus theory, this study examine the impact of framing on the consumer's choice in multi-alternative set and analyzes the manner in which he/she selects or rejects an alternative. The data obtained from experiment shows that : 1. Consumers focus on the positive attributes of in selection task, however, in rejection task he/she will focus on negative attributes. 2. Consumers are not influenced by prevention framing when he/she selects an alternative however, he/she is not influenced by promotion framing when reject an alternative. Understanding the underlying cognitive process of choosing abd rejecting in multiple alernatives can help marketers to create effective framing strategies for the bundle product.

Effects of Omni-channel Service Characteristics on Utilitarian/Hedonic Shopping Value and Reuse Intention (옴니채널 서비스 특성이 실용적·쾌락적 쇼핑가치 지각과 재이용의도에 미치는 영향)

  • Shin, Jong-Kuk;Oh, Mi-Ok
    • Journal of Digital Convergence
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    • v.15 no.10
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    • pp.183-191
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    • 2017
  • This study tries to explain the relationships among omni-channel service characteristics, utilitarian/hedonic shopping value, and reuse intention. We derive instant connectivity, localization, consistency, integration, privacy risk as omni-channel service characteristics from previous studies and collect data from 190 omni-channel service users. The major findings are as follows. First, localization, consistency, and privacy risk have a significant effect on utilitarian shopping value but no significant effect on hedonic shopping value. Second, instant connectivity and integration have a positive effect on both utilitarian and hedonic value. Third, utilitarian and hedonic shopping value have a positive effect on reuse intention. This study extends the scope of omni-channel consumer behaviors by focusing on multi-dimensionality of shopping value. The results of this research can provide useful implications for practitioners to build successful strategies on omni-channel service.