• Title/Summary/Keyword: Mu-Wi

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Improvement of Ergone Production from Mycelial Culture of Polyporus umbellatus

  • Lee, Wi-Young;Park, Young-Ki;Ahn, Jin-Kwon
    • Mycobiology
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    • v.35 no.2
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    • pp.82-86
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    • 2007
  • Ergone, a fungal metabolite derived from ergosterol, was previously isolated and identified from Polyporus umbellatus. Ergone is a major component of P. umbellatus known to have anti-aldosteronic diuretic effect and also displays cytotoxic activities. Most of mushroom's fruit bodies used for test contained less than 10 ${\mu}g/g$ of ergone. But P. umbellatus have larger amount of ergone than any other mushrooms. In order to improve the ergone production from the submerged culture of P. umbellatus, several factors including medium composition, culture conditions (temperature and pH) and different combinations of co-cultivation with various mycelia were studied. Among various carbon sources examined, starch proved to be most effective for the production of mycelia. The optimum pH and temperature for a flask culture of P. umbellatus mycelia were found to be 4.5 and $25^{\circ}C$, respectively. Under the optimized culture conditions, both the ergone production (86.9 ${\mu}g/g$) and mycelial growth (3.5 g/l) increased when P. umbellatus was cultured with Armillariella mellea. When the optimized conditions were applied, both mycelium and ergone production were significantly enhanced.

Fabrication of Biaxially Textured Ni Tapes from Ni Powder Compact Rods (분말 성형체로부터 양축정렬 집합조직을 갖는 니켈 테이프의 제조)

  • 이동욱;지봉기;주진호;김찬중
    • Journal of Powder Materials
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    • v.10 no.4
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    • pp.241-248
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    • 2003
  • Biaxially textured Ni tapes were fabricated by a cold working and recrystallization heat treatment processes from powder compact rods. The processing parameters associated with the cube texture formation in Ni tapes were systematically investigated by using X-ray diffraction and pole-figure analysis. The Ni powder used in this study was 5 $\mu$m in size and 99.99% in purity. To find the optimum sintering temperature, tensile tests were performed for Ni rods sintered at various temperatures. The Ni rods sintered at 100$0^{\circ}C$ showed poor elongation and low fracture strength, while the Wi rods sintered above 100$0^{\circ}C$ revealed good mechanical properties. The higher elongation and fracture strength of the Ni rods sintered at higher temperatures than 100$0^{\circ}C$ are attributed to the full densification of the sintered rods. The sintered Ni rods were cold-rolled with 5% reduction to the final thickness of 100 $\mu$m and then annealed for development of rube texture in rolled Ni tapes. The annealed Ni tapes depicted strong cube texture with FWHM(full-width at half-maximum) of in-plane and out-of-plane in the range of 8$^{\circ}$ to 10$^{\circ}$. The NiO deposited on the Ni tapes by MOCVD process showed good epitaxy with FWHM=10$^{\circ}$, which indicates that the Ni tapes can be used as a substrate for YBCO coated conductors.

A Measurement of the Exposure Rates by Terrestrial y-rays in Taegu Area (대구지역(大邱地域) 지각(地殼) ${\gamma}$-선(線)의 조사선량율(照射線量率) 측정(測定))

  • Chang, Si-Ho;Jeong, Chun-Gyun;Kang, Hee-Dong;Lee, Mo-Sung;Choi, Mun-Kyu;Kim, Wi-Soo
    • Journal of Radiation Protection and Research
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    • v.19 no.2
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    • pp.121-132
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    • 1994
  • This study concerns about the measurement and the investigation of environmental radiation characteristics which the components and the distribution of exposure rates by terrestrial y-rays in Taegu area. $4^{'}{\phi}{\times}4^{'}$ NaI(T1) scintillation detector with a multichannel analyzer was used in the measurement of y-rays as a part of in-situ spectrometry at twenty eight different locations in this area. The conversion into the exposure rate from the measured ${\gamma}-ray$ spectrum has been carried out leading to a net exposure rate and component ones by $^{40}K,\;^{238}U$ series and $^{232}Th$ series products which are known by the major parts in the terrestrial ${\gamma}-rays$ generally. As a result, the average exposure rate by the terrestrial ${\gamma}-rays$ in Taegu area is $9.4{\mu}R/h$ and the distribution of individual exposure rates shows more or less differences between these locations even after the consideration of diurnal and yearly variations which are always involved in these measurements. The component parts of exposure rates are distributed $^{40}K\;2.9{\sim}4.6{\mu}R/h,\;^{238}U$ series $1.2{\sim}3,\;1{\mu}R/h,\;^{232}Th$ series $2.5{\sim}5.0{\mu}R/h$ over the measured locations.

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Effects of Jasmonic Acid on Root Growth and Eleutheroside Accumulation in Adventitious Root Culture of Eleutherococcus koreanum (섬오갈피나무 부정근(不定根) 배양(培養)에서 부정근(不定根)의 생장(生長)과 Eleutheroside 류(類)의 생산(生産)에 미치는 Jasmonic acid 처리(處理)의 영향)

  • An, Jin-Kwon;Park, So-Young;Lee, Wi-Young;Park, Yeongki
    • Journal of Korean Society of Forest Science
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    • v.95 no.1
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    • pp.32-37
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    • 2006
  • The influence of different doses of jasmonic acid on both biomass of adventitious roots and accumulation of secondary metabolite in bioreactor cultures of Eleutherococcus koreanum was studied. The maximum growth (2.9 g Dry Weight/L) of adventitious roots was observed in the absence of jasmonic acid. The biomass of adventitious roots decreased with the increase in jasmonic acid dosage. High level of jasmonic acid efficiently stimulated the production of both eleutheroside B and E. The highest eleutheroside B ($49.0{\mu}g/g\;DW$) was observed at 0.4 mg/L jasmonic acid. Jasmonic acid at 0.2 mg/L led to the maximum accumulation of eleutheroside E ($64.7{\mu}g/g\;DW$). Whereas eleutheroside $E_1$ was maximally $19.0{\mu}g/g\;DW$ accumulated in the absence of jasmonic acid, the total eleutheroside ($259.9{\mu}g/L$) was the highest when 0.01 mg/L jasmonic acid was treated. In this study, the level of eleutheroside B decreased whereas the maximum levels of eleutheroside E and eleutheroside $E_1$ were observed at 10th and 4th day after jasmonic acid treatment.

Vertical Distribution of Heavy Metal Concentrations in Sediment Cores and Sedimentation Rate Using $^{210}Pb$ Dating Technique in the Juam Reservoir (주암댐 호저 퇴적물에서의 수직적 중금속 분산과 $^{210}Pb$를 이용한 퇴적속도산정)

  • Lee Pyeong-Koo;Youm Seung-Jun;Yeon Gyu Hun;Chi Se-Jung;Kim Ji-Wook;Oh Chang-Whan;Kim Sun-Ok
    • Journal of Soil and Groundwater Environment
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    • v.10 no.1
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    • pp.43-57
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    • 2005
  • Twelve bottom sediments and three cores were collected in Juam reservoir for a study on transportation, which was controlled by particle grain size (2mm-200{\mu}m,\;200-100{\mu}m,\;100-50{\mu}m,\;50-20{\mu}m,\;<20{\mu}m), and vertical distribution of heavy metals. Sediment cores were sliced into 2 to 5 cm intervals to measure heavy metal concentrations in interstitial water and sediments with depth. Pb isotopic compositions of core samples were determined to calculate sedimentation rate. Regardless of sampling sites, levels of heavy metals and trace elements in bottom sediments are nearly constant with mean values of $14.9\;{\mu}g/g\;for\;As,\;0.81{\mu}g/g\;for\;Cd,\;30.7{\mu}g/g\;for\;Cu,\;34.7{\mu}g/g\;for\;Ni,\;63.3{\mu}g/g\;for\;Pb\;and\;87.9{\mu}g/g\;for\;Zn$. In general, Cu, Pb, Zn, Wi, and Cr in fraction of $<20{\mu}m$ exhibit the highest concentration, but content of As is the highest in grain size of $2\;mm-200\;{\mu}m$ and $200-100\;{\mu}m$. Fe and Mn occur as the dissolved compositions of the highest concentrations in interstitial waters and increase in their concentrations toward lower part of cores. On the contrary, concentrations of Zn and Cu show the highest value in the uppermost part in cores, suggesting these elements are released from reductive dissolution of hydroxides and oxidation of organic matters under different redox conditions. The highest accumulations of Cu, Ni, Pb, and Zn contents in the sediment cores are observed at 0-4 cm layers, and concentrations of Cu and Pb are especially high, implying these heavy metals are originated from anthropogenic sources. The apparent sedimentation rate estimated using unsupported $^{210}Pb$ is 0.91 cm $year^{-1}$, corresponding about 10 cm sedimentation in total depth since construction of Juam dam. These results will provide available information for management of bottom sediment in Juam reservoir.

Speed Control Characteristics of BLDCM by CR-PWM VSI of Constant Switching Frequency (일정 스위칭 주파수의 CR-PWM VSI에 의한 BLDCM의 속도제어 특성)

  • Kim, Jang-Mok;Kim, Kwang-Heon;Won, Jong-Soo
    • Proceedings of the KIEE Conference
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    • 1990.11a
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    • pp.53-57
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    • 1990
  • This paper propose Constant Frequency CR-PWM VSI. In which ON/OFF output of Hystersis comparator, which compares the amplitude of reference current with that of actual current, control the switching elements with a constant sampling period of $\mu$-processor. Speed control system of BLDCM driven by controller wi th CF CR - PWM VSI was built.

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Integrated Methods For Successful Product Design (성공적 신제품 개발을 위한 통합적 접근 방법 -디자인 컨셉트(Design Concept)의 평가방법에 비중을 두고서)

  • 우홍룡
    • Archives of design research
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    • v.6 no.1
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    • pp.1-10
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    • 1993
  • This paper described design as a purposeful human activity for solving its problems. This means, problem solving is finding a way to get from some initial situation to a desired goal.In order to do this, like a voyage, there should be a compass, and a route map to guide the designer through the design process. Evaluation gives information about the way a design is proceeding and suggests the direction in which change should be made in order that the complex of design concepts should be fulfilled in a satisfactory manner.I think Pugh's total design model discussing in this paper takes a layered approach through a series of sequential actions, part of which is to find the product status. Each layer has the $$\mu$ti-dimensional elements, Product Design Specification (PDS) around the design core. I made a comparative study of several evaluation tools wi th Pugh's model and examined the criteria for evaluation and the rating / weighing methods.It needs, however, more study in order that PDSs may have its values and be fixed from the dynamic design concepts.

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Time Resolced Molecular Beam Characteristic in a Pulsed Supersonic Jet

  • Gang, Wi Gyeong;Kim, Eun Jeong;Choe, Chang Ju;Jeong, Gwang U;Jeong, Gyeong Hun
    • Bulletin of the Korean Chemical Society
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    • v.16 no.3
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    • pp.238-243
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    • 1995
  • A pulsed molecular beam source having short pulse duration (typically 70 ${\mu}s)$ and narrow velocity distribution (${\Delta}$v/v=8% for helium) has been costructed utilizing a commercial fuel injector. Beam characteristics of helium and ammonia seeded in helium expansions are accomplished by the use of an electron impact time-or-flight mass spectrometer. The comparisons between experimental data and theoretical calculations show that the proper beam speed is important to predict the evolution of stream temperature and valve shutter function. The decreasing tendency of pulse duration with increasing cluster size leads to the conclusion that the cluster beam property is described as a function of cluster mass and disinct cluster temperature.

Cadmium induces apoptosis in human lung fibroblast by inducing oxidative stress: A role of Bax and Bcl-2

  • Oh, Seon-Hee;Lee, Guang-Yong;Lee, Mi-Ock;Moon, Chang-Kiu;Lee, Byung-Hoon
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.106.1-106.1
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    • 2003
  • Cadmium (Cd) is an inorganic toxicant of great environmental and occupational concern which was classified as a human carcinogen in 1993. Occupational cadmium exposure is associated with lung cancer in human. In the present study, we established the mechanistic basis of apoptotic cell death induced by Cd in WI38 human lung fibroblast. Cd at 20-80 ${\mu}$M decreased viablility of cells in a concentration-dependent manner. PI staining, TUNEL staining and DNA fragmentation analysis demonstrated the apoptotic cell death by Cd. (omitted)

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Sasang Constitutional Medicine and Incurable Disease (사상의학(四象醫學)과 난치성질환(難治性疾患))

  • Park, Gae-Su;Song, Il-Byung
    • Journal of Sasang Constitutional Medicine
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    • v.14 no.3
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    • pp.1-6
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    • 2002
  • 1.Objects of Research This research is purposed to find methods of treatment on serious diseases, through summarizing etiology, classification and treatment on serious diseases proposed in Sasang constitutional medicine 2.Methods of Research It was researched as bibliologically with Dong-mu's chief medical writings such as ${\ulcorner}$Dongyi Soose Bowon(東醫壽世保元)${\lrcorner}$, ${\ulcorner}$Dongyi Soose Bowon Sasang Chobongyun(東醫壽世保元四象草本卷)${\lrcorner}$ 3.Results and Conclusions 1. The principle of treatment in the previous medicine is to treat each disease by 'Assisting-Good Qi' and 'Removig-Bad Qi'. but The principle of treatment in Sasang Constitutional medicine is to manage incurable disease by helping 'Essential Qi of each constitution(體質正氣)' 2. Incurable disease is classified into a chronic disease by 'Nature(性氣)' and a acute disease by 'Emotion(情慾)'. Both diseases became serious through 'Noi-Ok(牢獄)' and 'Wi-Gyoung(危傾)'. A chronic disease is much in the middle years of life and become senile disease. A acute disease is much in the young years of life and make patients die young. 3. prognoses of incurable disease are different from degree of Inherent vitality(命脈實數) and term of disease. The case in which Inherent vitality is exhausted is thought that is unable to treat. 4. The prevention of incurable disease Is more important the treatment of one in Sasang Constitutional Medicine. but if incurable disease is caught, Medicine(醫藥) and management(調養) must be used together for treatment of incurable disease. Medicine is more important in the level of 'Noi-Ok(牢獄)' and management is more important in the level of 'Wi-Gyoung(危傾)'. 5. Therefore, incurable disease should be treated by method that 'Essential Qi of each constitution(體質正氣)' is recovered and declination is removed through 'controlling mind(治心) and correcting Qi(正氣), so then the state of 'Golden mean(中庸)' is reached.

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