• Journal of Microbiology and Biotechnology
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• v.23 no.6
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• pp.771-778
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• 2013

Essential oils are increasingly of interest for use as novel drugs acting as antimicrobial and antiviral agents. In the present study, we report the in vitro antiviral activities of 29 essential oils, extracted from Chinese indigenous aromatic plants, against the tobacco mosaic virus (TMV). Of these essential oils, those oils from ginger, lemon, tea tree, tangerine peel, artemisia, and lemongrass effected a more than 50% inhibition of TMV at 100 ${\mu}g/ml$. In addition, the mode of antiviral action of the active essential oils was also determined. Essential oils isolated from artemisia and lemongrass possessed potent inactivation and curative effects in vivo and had a directly passivating effect on TMV infection in a dose-dependent manner. However, all other active essential oils exhibited a moderate protective effect in vivo. The chemical constitutions of the essential oils from ginger, lemon, tea tree, tangerine peel, artemisia, and lemongrass were identified by gas chromatography and gas chromatography-mass spectrometry. The major components of these essential oils were ${\alpha}$-zingiberene (35.21%), limonene (76.25%), terpinen-4-ol (41.20%), limonene (80.95%), 1,8-cineole (27.45%), and terpinolene (10.67%). The curative effects of 10 individual compounds from the active essential oils on TMV infection were also examined in vivo. The compounds from citronellal, limonene, 1,8-cineole, and ${\alpha}$-zingiberene effected a more than 40% inhibition rate for TMV infection, and the other compounds demonstrated moderate activities at 320 ${\mu}g/ml$ in vivo. There results indicate that the essential oils isolated from artemisia and lemongrass, and the individual compound citronellal, have the potential to be used as an effective alternative for the treatment of tobacco plants infected with TMV under greenhouse conditions.

• Korean Journal of Veterinary Research
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• v.36 no.3
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• pp.599-605
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• 1996

This study was designed to examine the mechanism of penile erection in adult bull by analyzing the responses of bovine proximal retractor penile muscle strips(BRP) to electtical field stimulation(EFS), exogenous nitric oxide(NO), NO synthesis precursor(L-arginine), NO synthase inhibitors(L-NAME, L-NMMA), guanylate cyclase inhibitor(methylene blue) and nonspecific potassium channel blocker(tetraethylammonium, TEA) treatments. Isometric tension of BRP was measured using physiograph. Results were summarized as follows: 1. EFS of nonadrenergic noncholinrgic(NANC) nerve in BRP produced frequency-dependent inhibitory responses to the contraction induced by co-treatment of epinephrine, guanethidine and atropine. The inhibitory responses to EFS were blocked by tetrodotoxin(TTX, $1{\mu}M$). 2. Treatment of L-NAME ($10,\;20{\mu}M$) inhibited the relaxation to EFS whereas L-NMMA ($100{\mu}M$) had no effect. 3. Treatment of NO($20,\;40{\mu}M$; as an acidified solution of $NaNO_2$) induced concentration-dependent relaxation whereas preincubation of TTX($1{\mu}M$) and L-NAME($20{\mu}M$) had no effect on the relaxation response. 4. L-arginine treatment(10mM) blocked the inhibitory effect of L-NAME($20{\mu}M$). 5. Pretreatment of methylene blue($40{\mu}M$) reduced the NANC-induced relaxation of BRP. 6. Tetraethylammonium(TEA, 80mM) reduced NANC relaxation. These results suggest that NO may act as a NANC neurotransmitter in BRP and the effects might be mediated by cGMP and potassium channel.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.24 no.1
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• pp.70-78
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• 1991

Both long period of summer drought and unusual high water temperature in 1988 caused the harmfull effect to the aquacultural organisms in south coast of Korea. One of those was the mass mortality of arkshell seedlings in Jinhae Bay. The purpose of this study was to verify the effects of environmental factors on arkshell seedlings by investigating not only water quality and food organisms in culturing grounds, but also meteorological conditions. Water temperature in November was higher at $2.0^{\circ}C$ than mean water temperature and the concentration of total inorganic nitrogen and N/P ratio were $0.38{\mu}g-at/l,$ 0.98, respectively which indicated the exhaustion of nutrients, especially nitrogen in the study area. In analysis of phytoplankton population structure, species diversity index(H) , equitability-index(e), species richness $index(d_1)$ were low, but dominance $index({\delta}_2)$ was high at the value of 98.4 and dominant species was Nitzschia pungens. In conclusion, it seems that mass .mortality of arkshell seedlings in November was resulted from the metabolism disorder with poor food organism under the unstable marine environment.

• Journal of KIEE
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• v.11 no.1
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• pp.27-32
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• 2001

In this study, the luminance, luminous efficiency and address time of an PDP as a parameter of the phosphor thickness and the size of discharge space are investigated. The maximum luminance and luminous efficiency are obtained at the phosphor thickness of 30 ${\mu}{\textrm}{m}$ for the rib height of 110 ${\mu}{\textrm}{m}$. For the rib height of 120~160 ${\mu}{\textrm}{m}$, the maximum values are obtained at the thickness of 50 ${\mu}{\textrm}{m}$ regardless of the kind of R, G and B phosphor. These results do not affected by the variation of discharge space. The average decrease rate of the total charge to the phosphor thickness is about 3.35pc/cell/10 ${\mu}{\textrm}{m}$ and the average increase rate of the addressing time is about 0.027 $mutextrm{s}$/10 ${\mu}{\textrm}{m}$.

• Korean Journal of Veterinary Research
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• v.35 no.2
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• pp.279-285
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• 1995

To characterize non-adrenergic non-cholinergic(NANC) nerve mediated contractile responses in circular smooth muscle of bovine reticular groove, we investigated NANC relaxation and contraction induced by electric field stimulation to enteric nerves. In the presence of atropine($1{\mu}M$) and guanethidine($50{\mu}M$), electric field stimulation at frequency of 1 to 16Hz(square pulses, 0.5ms duration, 70V) evoked clear-cut relaxations through stimulations. Transient 'rebound contraction' was occured when the stimulus was switched off. All of the responses (relaxation and rebound contraction) were dose-dependently blocked by Nw-nitro-$_{\small{L}}$-arginine methyl ester(L-NAME), an inhibitor of nitric oxide synthesis, and methylene blue, and inhibitor of soluble guanylate cyclase. Tetraethyl ammonium(TEA), a potassium channel blocker, did not block the NANC relaxations.

• Journal of Aquaculture
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• v.6 no.2
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• pp.63-69
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• 1993

Various scales of red tides have frequently occurred in the southern coastal waters of the Korean Penninsula since the late 1970's. Because most shellfish and finfish farms in Korea are located in the southern coastal waters, the impacts of red tides on the aquaculture have been increasing significantly. The Puksin Bay is one of the places where red tides have occurred almost every year since the early 1980's. During $1990\~1991$, mass mortalities of aquacultural species by the red tides were recorded. The causative organisms in this period were Leplocylindrus danicu(November '90 and June '91), Skeletonema costatum(December '90 and August '91), Nitzschia seriata(August '91), and Gymnodinium splendens(July '91). The maximum chlorophyll-a content was $265.7{\mu}g/l$ in the tides. Frequent red tides are associated with the eutropication of the bay. Some relationships between red tides' occurrence and europhication are herein discussed.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2007.11a
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• pp.138-139
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• 2007

The microstructure and micro-hardness of high velocity oxygen fuel-sprayed (HVOF) WC-CoCr coatings are comparatively studied for both before and after laser heat-treatment (LT) of the coatings. The results indicate that compared to HVOF WC-CoCro coating, the laser treatment has eliminated the pores almost entirely providing a more homogeneous and densified microstructure. And the compact interface of the coating with substrate is achieved by laser treatment. The thickness of the coating has decreased from 300 ${\mu}m$ to 225 ${\mu}m$ As a result, the average porosity is five times higher in HVOF coating than in the coating by laser treatment. The laser treatment has produced a considerable increment in the hardness of the coating near surface whose average value increases from Hv0.2=1262.4 in the HVOF-sprayed coating to Hv0.2=1818.7 in the coatings treated with laser.

• Journal of Korean Vacuum Science & Technology
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• v.6 no.2
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• pp.62-66
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• 2002

Hydraulic pumps are used to control the landing wheels of aircrafts, and their proper operation is vital to plane safety It is well hewn that adhesive wear failure is a major cause of pump failure. A dual nitrogen plasma immersion ion implantation process calling for the implantation of nitrogen at two different energies and doses has been developed to enhance the surface properties of the disks in the pumps. The procedures meet the strict temperature requirement of <200$^{\circ}C$, and after the treatment, the working lifetime of the pumps increases by more than a factor of two. This experimental protocol has been adopted by the hydraulic pump factory as a standard manufacturing procedure.

• IE interfaces
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• v.10 no.1
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• pp.95-107
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• 1997

본 논문은 실험계획법을 반도체 공정 및 소자 시뮬레이터에 적용하여, 시뮬레이션 회수를 최소화하고, 동시에 현장과 유사하게 시뮬레이터 내부 파라미터가 튜닝 될 수 있도록 하는 교정 문제에도 활용된 반도체 공정 최적화 사례를 소개한다. 또한, 일반적 시뮬레이터가 실제 현장과의 차이점으로 갖는 문제인 동일한 입력 값에 대해 항상 같은 출력 값이 산출되는 점을 공정의 규격을 고려해 시뮬레이션 함으로써 현장에서의 재현성을 높이고자 하였다. 이는 $0.8{\mu}m$급 BIMOS 공정의 기본 소자 중 하나의 NPN 트랜지스터의 전류이득(Current Gain : hFE) 특성을 최적화하기 위한 주요 공정조건 결정과 연관된 것이며, 기존 방법에 비해 시뮬레이션 횟수를 줄이는 동시에 현장에 직접 투입되는 검증 로트를 최소화시켜 비용과 시간을 절감할 수 있었다. 또한, 얻어진 추전 조건에서 실제 생산된 검증 로트를 통해 시뮬레이션으로부터 얻어진 결과들이 재현됨으로써 제시된 방법의 유용성을 확인하였다.

• Geomechanics and Engineering
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• v.20 no.4
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• pp.275-285
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• 2020

Excavation usually induces considerable ground settlement in soft ground, which may result in damage of adjacent buildings. Generally, the settlement is predicted through elastic-plastic finite element method and empirical method with defects. In this paper, an analytical solution for predicting ground settlement induced by excavation is developed based on the definition of three basic modes of wall displacement: T mode, R mode and P model. A separation variable method is employed to solve the problem based on elastic theory. The solution is validated by comparing the results from the analytical method with the results from finite element method(FEM) and existing measured data. Good agreement is obtained. The results show that T mode and R mode will result in a downward-sloping ground settlement profile. The P mode will result in a concave-type ground settlement profile.