• Child Health Nursing Research
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• v.20 no.1
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• pp.30-38
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• 2014

Purpose: The purpose of this study was to explore maternal physical activity support for preschool children. Methods: Survey methodology using a self-administered questionnaire was employed. Mothers with preschool children from a daycare center in Daejeon participated in the study. One hundred and fifty-six questionnaires were analyzed. Results: Mothers with preschool children showed a moderate level of physical activity support for their children. Significant factors affecting physical activity support of mothers were monthly household income (${\beta}$=.417, p=.002), maternal self-efficacy for physical activity support (${\beta}$=.231, p=.003), information for physical activity support (${\beta}$=.173, p=.022), and experience of education about physical activity support (${\beta}$=.237, p=.002). These variables explained 26.4% of the variance in physical activity support (F=7.628, p<.001). Conclusion: To improve maternal support for increasing physical activity of preschool children, maternal education and appropriate information should be provided to improve self-efficacy for physical activity support.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.11
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• pp.7934-7940
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• 2015

The raise of the acceleration can be one of possible methods to increase the scheduled speed of the metropolitan railway system. It is possible to raise the acceleration to the some point by increasing the traction power of the motor. However, there is a limit of the acceleration because the traction power over some level related to the adhesion causes a slip, which prevents from accomplishing the target acceleration. The running resistance is also an important factor to consider. Both the adhesion and the running resistance as well as the traction power vary according to the velocity. Therefore, the standardization of the acceleration needs the analysis of these factors as a function of velocity. In this study, we focus on the advanced urban transit unit(AUTS) for the standardization. We derive a novel equation of the adhesion suitable for the AUTS by investigation of the traction and adhesion equation as well as the experiment data. And finally we propose the standard of the acceleration based on this analysis.

• The Korean Journal of Pain
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• v.18 no.1
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• pp.39-42
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• 2005

Background: Besides its general anesthetic effect, ketamine interacts with sodium channels in a local anesthetic-like fashion, including the sharing of binding sites with those commonly used by clinical local anesthetics. This study evaluated the dose related effects of ketamine during epidural anesthesia with 0.5% ropivacaine. Methods: Sixty ASA physical status I II patients, scheduled for minor elective surgery under epidural anesthesia using 0.5% ropivacaine, were randomly divided into three groups (n = 20 each). The patients initially received either 0.5% ropivacaine (group 1), ketamine (0.1 mg/kg) in addition to the epidural 0.5% ropivacaine (group 2) or ketamine (0.2 mg/kg) in addition to the epidural 0.5% ropivacaine (group 3). The regression of sensory block was assessed by transcutaneous electric stimulation (TES), equivalent to a surgical incision. Motor block was assessed using the Modified Bromage's scale. Episodes of bradycardia, hypotension and sedation were also recorded. Results: There were no significant differences among the three groups in the maximal levels of sensory block or the times taken for these levels to be reached. The mean times for the block to regress to two and four segments below the maximal level were significantly prolonged by epidural ketamine. Conclusions: Epidural ketamine prolongs the duration of ropivacaine epidural anesthesia. These results suggest that ketamine has local anesthetic-like actions.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.19 no.1
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• pp.17-24
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• 1983

The authors carried out an experiment to find the optomotor response of killifish, Orizias latipes(TEMMINCK et SCHLEGEL) and Yellowtail, Seriola quinqueradiata (TEMMINCK et SCHLEGEL) according to the colors of the netting pattern on the visual screen and the revolving velocities of the visual screen. The experimental water tank was made of 0.5 cm thick transparent acryl in the cylindrical shape (100R$\times$42H cm). The water level in the tank was maintained 30cm high from the bottom. The colors of the netting pattern (mesh size: 19.1cm, width of netting twine: 1.5cm, hanging ratio: 84%) on the three visual screens were black, red and green respectively. The revolving velocities of the visual screen were controlled by pulley, bevel gear and variable speed motor in three steps; slow (15.0cm/sec), middle (37.4cm/sec) and high (62.9cm/sec). The fish was put into the water tank before each experiment and released in it for 30 minutes in order to acclimatize itself to the tank. The visual screen was revolved for 4 minutes per each experiment, at first the fish was released for 1 minute, and then the behavior of the fish was observed for 3 minutes. In the course of clockwise and counter clockwise experiments, 10 minutes-pause was given for the rest. The behavior of the fish was observed by video system, and rounding number and swimming speed of the fish were analysed. The results obtained are as follows: (1) Optomotor response rate of Killifish and yellowtail were 95% and 94% respectively. (2) Response of the fish according to the colors of the netting pattern on the three visual screens was best in black, and second in red and third in green. (3) Response of the fish according to the revolving velocities of the visual screen was best in high speed, and second in middle speed and third in slow speed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.493-501
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• 2016

In this study, core technologies of a traction system on a mountain tram operating on the track of mountain road full of sharp curves and steep gradients were developed. In domestic mountain resort areas, sometimes the transportation service is not provided in winter because of ice and heavy snow on roads, so a mountain railway service independent of the climate and geographic conditions is needed. A traction system was designed taking into account of the power of a traction motor to climb the gradient of 120 ‰, which is common in domestic mountainous areas. and power transmission system was designed to consider the installation space for the traction system. In addition, a reduction gear and a propeller shaft were developed. An elastic pinion was developed and applied to the rack & pinion bogie system for steep gradient so that noise and vibration generated by contact between the steel gears could be reduced. Impact comparison tests showed that the vibration level of the elastic pinion is one-third lower than that of previous steel pinion. Independent rotating wheels and axles were developed for the bogie system to operate on the sharp curve of a 10 meter radius. In addition, the band braking system was developed to enhance the braking force during running on the steep gradient. A test for the braking force showed it exerts the required braking force. The performance of the developed core components were verified by the tests and finally they were applied to the bogie system running on the track of steep gradient and sharp curve.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.34 no.1
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• pp.37-44
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• 2023

Objectives: Tic disorders are highly heritable; however, growing evidence suggests that environmental factors play a significant role in their pathogenesis. Studies on these factors have been inconsistent, with conflicting results. Therefore, this study aimed to examine the associations of pre- and perinatal exposure to Tourette syndrome (TS) or chronic tic disorders (CTD) in Korean school-aged children. Methods: This case-control study used data from a large prospective cohort study. The primary outcome was TS/CTD diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) criteria and Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean Version. Demographic, pre-, and perinatal information was obtained from the maternal questionnaires. Data between the TS/CTD and control groups were compared using the chi-squared or Student's t-test, as appropriate. Two-step logistic regression analyses were used to test the association between TS/CTD and pre- and perinatal risk factors. Results: We included of 223 children (78 with TS/CTD and 145 controls). Significant differences in the demographic data between the two groups were observed. The male sex ratio, mean parental age, parental final education level, and family history of tics were included as confounders. In the final adjusted multivariable model, TS/CTD was significantly associated with antiemetic exposure during pregnancy (odds ratio [OR]=16.61, 95% confidence interval [CI] 1.49-185.22, p=0.02) and medically assisted reproduction (OR=7.89, 95% CI 2.28-27.28, p=0.01). Conclusion: Antiemetic exposure and medically assisted reproduction are significantly associated with the risk of TS/CTD. These results should be replicated in future prospective and gene-by-environment studies.

• Physical Therapy Korea
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• v.30 no.2
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• pp.128-135
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• 2023

Background: Despite the fact that aquatic exercise is one of the most popular alternative treatment methods for children with cerebral palsy (CP), there are few research regarding its effectiveness. Objects: The purpose of this study was to examine the effects of aquatic exercise on upper extremity function and postural control during reaching in children with CP. Methods: Ten participants (eight males and two females; 4-10 years; Gross Motor Function Classification System levels II-IV) with spastic diplegia were recruited to this study. The aquatic exercise program consisted of four modified movements that were selected from the Halliwick 10-point program to enhance upper extremity and trunk movements. The participants attended treatment two times a week for 6 weeks, averaging 35 minutes each session. The Box and Block Test (BBT), transferring pennies in the Bruininks-Oseretsky Test (BOT), and pediatric reaching test (PRT) scores were used as clinical measures. Three-dimensional motion analysis system was used to collect and analyze kinematic data. Differences in BBT and BOT values among pre-treatment, post-treatment, and retention (after 3 weeks) were analyzed using a Friedman test. In addition, the PRT scores and variables (movement time, hand velocity, straightness ratio, and number of movement units) from the three-dimensional motion analysis were tested using a Wilcoxon signed-rank test. The significance level was established at p < 0.05. When the results appeared to be statistically significant, a post-hoc test for multiple comparisons was performed with the Wilcoxon signed-rank test. Results: All clinical measures, which included BBT, transferring pennies of BOT, and PRT, were significantly increased between pre-intervention and post-intervention scores and between pre-intervention and retention scores after treatment (p = 0.001). Three-dimensional motion analysis mostly were significantly improved after treatment (p = 0.001). Conclusion: Aquatic exercise may help to improve body function, activity, and participation in children with varying types of physical disabilities.

• Molecules and Cells
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• v.45 no.3
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• pp.134-147
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• 2022

The anti-oxidant enzyme heme oxygenase-1 (HO-1) is known to exert anti-inflammatory effects. From a library of pyrazolo[3,4-d]pyrimidines, we identified a novel compound KKC080096 that upregulated HO-1 at the mRNA and protein levels in microglial BV-2 cells. KKC080096 exhibited anti-inflammatory effects via suppressing nitric oxide, interleukin1β (IL-1β), and iNOS production in lipopolysaccharide (LPS)-challenged cells. It inhibited the phosphorylation of IKK and MAP kinases (p38, JNK, ERK), which trigger inflammatory signaling, and whose activities are inhibited by HO-1. Further, KKC080096 upregulated anti-inflammatory marker (Arg1, YM1, CD206, IL-10, transforming growth factor-β [TGF-β]) expression. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridinetreated mice, KKC080096 lowered microglial activation, protected the nigral dopaminergic neurons, and nigral damage-associated motor deficits. Next, we elucidated the mechanisms by which KKC080096 upregulated HO-1. KKC080096 induced the phosphorylation of AMPK and its known upstream kinases LKB1 and CaMKKbeta, and pharmacological inhibition of AMPK activity reduced the effects of KKC080096 on HO-1 expression and LPS-induced NO generation, suggesting that KKC080096-induced HO-1 upregulation involves LKB1/AMPK and CaMKKbeta/AMPK pathway activation. Further, KKC080096 caused an increase in cellular Nrf2 level, bound to Keap1 (Nrf2 inhibitor protein) with high affinity, and blocked Keap1-Nrf2 interaction. This Nrf2 activation resulted in concurrent induction of HO-1 and other Nrf2-targeted antioxidant enzymes in BV-2 and in dopaminergic CATH.a cells. These results indicate that KKC080096 is a potential therapeutic for oxidative stress-and inflammation-related neurodegenerative disorders such as Parkinson's disease.

• 한국노년학
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• v.30 no.3
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• pp.843-853
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• 2010

The purpose of this study is to find out the characteristics of elderly pedestrian accidents and to suggest policy implications to enhance the level of elderly pedestrian safety. Although much efforts has made to enhance traffic safety environment, pedestrian traffic accidents among elderly population are not significantly decreased. This is mainly because current traffic safety measures do not much consider the characteristics of elderly pedestrians in the aspects of physical and psychological conditions. Main findings from vehicle-pedestrian traffic accident data and survey are as follows. First elderly pedestrians have high probability of traffic accident near crosswalks or cross streets rather than on crosswalk or cross streets. Second they need more green light time for crossing the streets. Third, they feel motor cycles running on the side walk and parked vehicles on the side walk are the most dangerous factors. Forth, general drivers do not have reasonable understanding for the walking behaviors of elderly pedestrians. Fifth, elderly pedestrians frequently need to rest while walking. Sixth, elderly people do not see clearly or understand traffic signs. Finally, many elderly pedestrians experience accidents or inconvenience while walking on the sidewalk.

• The Journal of the Convergence on Culture Technology
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• v.10 no.3
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• pp.769-782
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• 2024

The purpose of this study analyzes by confirming the structural relationship between the four variables of Chinese college students' health beliefs, planned behavior, behavioral control, and exercise persistence, this study can establish measures to enhance and improve college students' health beliefs and planned behavior and improve behavioral control. The purpose is to provide basic data to improve the level of continued exercise among college students. The EBI study verified reliability and validity through a preliminary survey targeting 380 people. This survey distributed questionnaires to college students at 52 universities from May 12 to July 21, 2023, and a total of 5,109 copies were finally selected and analyzed, excluding invalid questionnaires. As a result of the study, first, the structural relationship between variables showed that health beliefs had a positive effect on planning behavior, behavioral control, and exercise persistence. Second, planning behavior was found to have a positive effect on behavioral control and motor persistence. Third, behavioral control was found to have a positive effect on exercise persistence. Fourth, planning behavior and behavioral control were found to play a positive mediating role in the relationship between health beliefs and exercise persistence. Therefore, to improve college students' health beliefs, schools should open a health psychology curriculum. Furthermore, there is a need to strengthen college students' beliefs about their health by developing and distributing customized health education programs for college students.