• 생물환경조절학회지
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• 제9권4호
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• pp.237-243
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• 2000

현재 온실에서 농작업을 작업기는 사람이 운전하고 있다. 온실 안은 무척이나 무덥고 열악한 작업조건이다. 그렇기 때문에 앞으로 무더운 온실내의 작업기 개발은 사람이 직접 운전하지 않고, 자동화에 의한 무인화 될 것으로 전망된다. 온실에서 자동화 및 무인화의 작업을 돕기 위하여 온실내의 경로(길)에 따라 자동적으로 이동할 수 있는 시스템을 개발하게 되었다. 이 시스템은 작업기의 자동화와 무인화를 위한 것이며, 이를 위하여 온실의 천장에 가이드를 연결한 후 이를 따라 시스템이 자동으로 이동할 수 있는 경로 자동변환 시스템이다. 이 시스템은 연마봉으로 만들어진 경로를 따라 선회 및 직선운동이 가능하며, 이 시스템은 경로 변경을 위한 리미트 스위치와 소프트웨어로 구성되어 있다. 이 시스템의 작동여부를 실험하기 위하여 시테핑모터를 가진 마이크로 마우스를 이용하였다. 견고한 실험실의 평면 위에서의 작동실험은 시스템 작동이 100% 성공률을 나타내었지만 모래위나 다른 조건에서는 성공률이 80% 이하로 낮게 나타났다. 실제 온실에서도 충분한 강도를 가진 연마봉을 이용하여 처짐에 대한 부분을 고려하여 사용한다면 경로를 따라 주행하는 이 시스템은 잘 작동할 수 있을 것으로 기대된다.

• Journal of Korean Neurosurgical Society
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• 제29권10호
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• pp.1296-1302
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• 2000

Objective : Traumatic brain injury including diffuse axonal injury has been shown to result in a decrease in brainfree magnesium concentration, an endogenous inhibitor of calcium entry into neuron, that is associated with the development of neurological motor deficits. The goal of this study is to establish the therapeutic window during which the therapy with $MgSO_4$ and/or hypothermia improve damaged neurons by TUNEL stain. Method : Moderate brain injury was induced in 64 adult Sprague-Dawley rats, weighing 350 to 450gm each, by using a simple weight-drop device(Marmarou model). The animals were randomly assigned to four groups(sixteen rats each, a control group, a group treated with $MgSO_4$, a group treated with hypothermia, and a group treated with $MgSO_4$ and hypothermia) and the rats in each group were sacrificed and studied after 12 hrs, 24 hrs, 1 wk, and 2 wks after insult. In hypothermic group, these rats were subjected to hypothermia after injury, with their rectal temperatures maintained at $32^{\circ}C$ for 1 hour. After 1-hour period of hypothermia, rewarming to normothermic level was accomplished over 30-minute period. In the groups treated $MgSO_4$, hypothermia and $MgSO_4$ were subsequently treated with $MgSO_4$($750{\mu}moles/kg$) infused intra-muscularly at 30 minutes after trauma. Result : In all treated groups, a significant reduction in TUNEL positive cells was found in comparison with the control group each time(p<0.001). Between treatment groups, No differnce was seen 12hrs, 24hrs, and 1wk. However, hypothermic group treated with or without $MgSO_4$ showed more significant reduction in apoptotic cells than group treated with $MgSO_4$ 2 weeks after trauma(p<0.05). However, hypothermic group treated with $MgSO_4$ showed no significant reduction in apoptotic cells compared with hypothermic group(p>0.05). Conclusion : These findings suggest that both hypothermia and $MgSO_4$ significantly improve pathological changes. Otherwise simultaneously $MgSO_4$ and hypothermia treatment groups is failed to provide additional neuroprotection. These results may be relevant to the design of future clinical trials of therapeutic hypothermia and $MgSO_4$ for traumatic brain injury.

• 한국산학기술학회논문지
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• 제19권4호
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• pp.117-122
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• 2018

대용량 3상 시스템 에어컨은 최근 들어 소비 전력 저감을 위해 인버터 회로를 포함하고 있다. 인버터 회로는 교류를 다이오드를 통해 정류하고 DC-link 전원부 콘덴서에 의해 평활된 직류를 사용한다. 이 때 평활에 사용되는 DC-link 전원부 콘덴서는 전압 리플, 전류 리플 조건을 만족하기 위해 전해 콘덴서가 일반적으로 사용된다. 콘덴서의 용량을 줄이게 되면 회로부의 크기 및 무게, 비용을 줄일 수 있게 된다. 본 논문에서는 최소점 추정 PPL(Phase Locked Loop) 위상 제어와 평균 전압 d축 전류제어 기법을 조합하여 입력 리플 전류를 약 90% 저감하는 알고리즘을 제안한다. 입력 리플 전류의 감소로 인해 DC-link 콘덴서의 전류 리플도 감소하므로 콘덴서의 용량을 줄일 수 있지만 전해 콘덴서의 경우 등가 직렬 저항(ESR : Equivalent Series Resistance)이 크기 때문에 발열로 인한 수명이 한계를 가진다. 본 논문에서는 전해 콘덴서 대신 DC-link 단에 전류 리플을 고려한 필름 콘덴서를 선정하는 방법을 제안한다. 필름 콘데서의 정전 용량 선정, 내압 선정, RMS(Root Mean Square) 전류 용량, RMS 전류 주파수 해석을 고려해 콘덴서의 용량을 선정할 경우 1680uF의 전해 콘덴서를 20uF로 용량을 낮추어 설계함으로써 전원부 콘덴서의 크기 및 무게, 비용을 줄였으며 전동기 구동을 통해 동작을 확인하였다.

• Molecules and Cells
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• 제43권4호
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• pp.360-372
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• 2020

The basal ganglia network has been implicated in the control of adaptive behavior, possibly by integrating motor learning and motivational processes. Both positive and negative reinforcement appear to shape our behavioral adaptation by modulating the function of the basal ganglia. Here, we examined a transgenic mouse line (G2CT) in which synaptic transmissions onto the medium spiny neurons (MSNs) of the basal ganglia are depressed. We found that the level of collaterals from direct pathway MSNs in the external segment of the globus pallidus (GPe) ('bridging collaterals') was decreased in these mice, and this was accompanied by behavioral inhibition under stress. Furthermore, additional manipulations that could further decrease or restore the level of the bridging collaterals resulted in an increase in behavioral inhibition or active behavior in the G2CT mice, respectively. Collectively, our data indicate that the striatum of the basal ganglia network integrates negative emotions and controls appropriate coping responses in which the bridging collateral connections in the GPe play a critical regulatory role.

• 디지털콘텐츠학회 논문지
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• 제19권8호
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• pp.1585-1592
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• 2018

휠체어에 대한 균형을 맞추지 못하는 체중 배분으로 인해 기존의 휠체어 시스템은 휠체어가 언덕으로 올라갈 때 뒤집히거나 떨어질 위험에 직면합니다. 이 논문에서는 휠체어를 타는 동안보다 안전하기 위해 통합 된 자이로 센서와 틸트 센서를 사용하여 균형을 제어하는 실시간 새 솔루션을 제안했습니다. 휠체어의 전형적인 특성은 발을 움직이는 데 어려움을 겪는 특수 사용자를위한 것이기 때문에 휠체어 시스템의 균형을 유지하는 것이 중요하고 도움이되었습니다. 우리의 방법에서는 경사 센서의 정보를 이용하여 시트 각을 계산한다. 그러나 휠체어가 움직이는 관성의 법칙으로 인해 틸트 센서의 출력 값에 편차가 있습니다. 따라서 자이로 센서의 출력 인 가속도를 이용하여 각도 값을 최적화해야합니다. Gyro 센서와 Tilt 센서의 조합을 사용하여 이점을 얻었습니다. 또한 전체 시스템의 소비 문제도 해결했습니다. ZigBee 센서 모듈을 사용하여 다양한 실험을 통해 밸런싱 시스템의 전력 소비가 크게 줄어 들었습니다.

• 대한소아치과학회지
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• 제35권2호
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• pp.351-356
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• 2008

뇌성마비(cerebral palsy)는 비진행성의 정신, 운동 장애를 총칭하는 용어로, 소아 장애의 흔한 원인이 된다. 자해 행위란(self-injurious behavior) 자살 의도없이 자신의 신체 일부를 고의적으로 손상시키는 것으로, 종종 반복적인 행동으로 나타난다. 소아에서의 이러한 자해 습관은 정상적인 어린이에서는 드물며, 증후군, 유전질환, 정신지체 어린이 등에서 그 발생률이 높게 보고된다. 구강 내 자해 행위의 가장 흔한 유형은 혀나 입술 혹은 구강 점막을 물어뜯는 것이다. 이러한 자해 행위를 조절하기 위하여 행동 수정법, 약물 치료, 신체 속박술, 치과적 장치의 적용, 외과적 수술 또는 치아 발치술 등의 다양한 방법들이 제시되었다. 이 중 마우스가드 등의 치과적 장치를 이용한 방법은 구강 내 자해 행위의 감소와 조직의 보호를 위해 가장 보존적이며 적합한 방법이라고 사료된다. 본 증례에서는 자해 습관에 의해 하순과 협점막에 궤양성 병소를 가진 뇌성마비 환아에 있어서, 변형된 마우스가드를 이용하여 자해에 의한 손상을 방지하고 만족할 만한 치유 양상을 보였기에 이를 보고하는 바이다.

• 대한한의학회지
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• 제24권2호
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• pp.66-80
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• 2003

Objectives : Recently, herbal acupuncture has been developed in the Korea since the earlier 1960' applied to various diseases including the cerebrovascular accident. The main characteristics of herbal acupuncture are a combination the merit of acupuncture and herbal medicine. It was not well known the therapeutic effect and the mechanism of herbal acupuncture on transient forebrain ischemic injury, although it has been used frequently in clinics. Ramulus Uncariae Cum Uncis (釣鉤藤) has been claimed to possess sedative, anti-spasmodic actions, and treat childhood epilepsy in oriental medical preparation. Also, it has been stated that Ramulus Uncariae Cum Uncis was antioxidatvie effect and neuroprotection against glutamateinduced neuronal death. Methods : In this study, effects of Ramulus Uncariae Cum Uncis' herbal acupuncture on the $GV_{20}{\;}or{\;}LR_3$, named Baek-hue or Tae-chung, on neuroprotection after the transient forebrain ischemia were investigated in Sprague-Dawely rats. Expressions of cFos, FosB and BDNF protein in the hippocampus and cortex were observed at 2 hrs and 48 hrs after transient forebrain ischemia by immunohistochemistry and ELISA technique. Results : Expression of cFos protein was increased slightly in the hippocampus and cortex at 2 hrs after transient forebrain ischemia, but FosB protein was increased highly comparing to cFos protein. However, pretreatment with Ramulus Uncariae Cum Uncis' herbal acupuncture on $GV_{20}{\;}or{\;}LR_3$ significantly increased expression of cFos protein and significantly decreased expression of FosB protein compared to control group, respectively. These features were observed in the motor cortex and retrosplenial granular cortex as well as the hippocampus. Especially, cFos expression was more increased at the herbal acupuncture on $GV_{20}{\;}than{\;}LR_3$, but FosB expression was more decreased in $LR_3$ group than $GV_{20}$ group. Also, pretreatment with Ramulus Uncariae Cum Uncis' herbal acupuncture on $GV_{20}{\;}or{\;}LR_3$ significantly increased the expression of BDNF protein in the hippocampus ($254.88{\pm}12{\;}pg/ml{\;}in{\;}GV_{20}$ group, $245.93{\pm}44.4{\;}pg/ml{\;}in{\;}LR_3$ group) and the cortex ($85.81{\pm}3.45{\;}pg/ml{\;}in{\;}GV_{20}$ group, $111.51{\pm}15.79{\;}pg/ml{\;}in{\;}LR_3$, group) compared to the hippocampus ($134.07{\pm}2.96{\;}pg/ml$) and the cortex ($61.16{\pm}4.11{\;}pg/ml$) in control group at 48 hrs after transient forebrain ischemia. Conclusion : These results suggest that pretreatment with Ramulus Uncariae Cum Uncis' herbal acupuncture on $GV_{20}{\;}or{\;}LR_3$ has neuroprotective effect on transient forebrain ischemia and the herbal acupunture on $GV_{20}{\;}or{\;}LR_3$ may be related to antioxidative effect and calcium channel block of Ramulus Uncariae Cum Uncis. Also, it could be mentioned there is specificity of acupoints treating ischemic injury through the difference between the herbal acupuncture of $GV_{20}{\;}and{\;}LR_3$.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 2000년도 THE THIRD INTERNATIONAL CONFERENCE ON AGRICULTURAL MACHINERY ENGINEERING. V.II
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• pp.472-479
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• 2000

A persimmon harvesting vehicle that can be operated in hilly orchards as well as a manipulator that can be used to harvest persimmons located in remote positions in the trees were designed and developed. The vehicle could be operated with keeping balanced position in an inclined field and its working platform could be moved up and down easy to approach fruits in a remote region with the aids of a hydraulic and a electrical and electronics systems. The weight of the vehicle was 927 kg and the center of gravity was located at 427 mm to the inner side from the center of a right driving caterpillar, 607 mm to a rear axle from the center of a front axle, and 562 mm to upward from ground. The automatic level control sensor for leveling the working platform was activated within 14.5 ∼ 16.5 degrees of slope variation. The total length of the manipulator was 1.39 m and weight is 975 g. It was powered by a 12 V geared motor to detach persimmon fruits with a rotational force. The gripper was made of plastic and rubber to increase a frictional force. In a performance evaluation test, static tipping angle, dynamic tipping angle toward front side when the vehicle was moving downward, climbing angle, driving speed of the vehicle were measured or calculated. In persimmon harvesting tests 24.9% of yield was increased by hand picking with the aid of the vehicle and additional 7% of yield were increased when the manipulator was used. Therefore, 99010 of total possible yield was achievable when both of the vehicle and the manipulator were used for the manual persimmon harvesting. Increase in 22.5% of total yield was achieved with the manipulator only.

• 한국산업보건학회지
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• 제29권4호
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• pp.464-476
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• 2019

Objectives: This study aimed to assess the exposure levels of tollbooth workers to diesel particulate matter using black carbon (BC) and to find the correlations among variables associated with BC using the motor vehicle management act regulated by the Ministry of Land, Infrastructure and Transport. Methods: This study was performed over 14 days at a university in Seoul. BC levels were monitored using an aethalometer and were conducted around the breathing zones of the workers. There were three sampling locations: inside the tollbooth (front gate and rear gate) and an office as a control group. T-test, correlation, and multiple linear regression analysis were performed using SPSS. Results: The geometric mean (GM) of BC_30min concentrations in the exposure group was 2.44 ㎍/㎥, approximately 1.4 times higher than the control group (1.75 ㎍/㎥). The GM of BC_30min concentrations was 2.75 ㎍/㎥ during the heavy traffic time (9-10 am) and 2.30 ㎍/㎥ during non-heavy traffic times (p<0.001). The multiple linear regression analysis shows that the number of all types of vehicles and PM_2.5 concentrations in the atmosphere were factors increasing the GM of BC(ln(BC_30min)) concentrations (adjusted R²=0.42, p<0.001). The workers were constantly exposed to low concentrations (GM of BC_30min=2.44 ㎍/㎥), but they were exposed to peak concentrations instantly (BC_10sec=3545.04 ㎍/㎥). When the GM of BC_30min concentrations was momentarily represented as high, it was identified that a vehicle mainly using diesel fuel or an aging vehicle had passed. Conclusions: A ventilation system should be installed in the closed tollbooth or aging vehicles should be controlled so as not to pass tollbooths.

• Korean Journal of Acupuncture
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• 제20권3호
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• pp.61-80
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• 2003

Objectives : Acupuncture and herbal medicine have been used to prevent and treat the cerebrovascular accident, such as a stroke, and many studies of acupuncture and moxibustion concerning to the stroke have been undertaken in the human and various animals. Recently, the new therapeutic tool, that is herbal acupuncture, has been developed since the 1950' and applied to various diseases including the cerebrovascular accident. The main characteristics of herbal acupuncture are a combination of acupuncture and herbal medicine. It was not well known the therapeutic effect and the mechanism of herbal acupuncture on transient forebrain ischemic injury, although it has been used frequently in clinics. Methods : In this study, effects of folium Artemisiae Argyi and moxa tar' herbal acupuncture on the $GV_{20}$, named Baek-Hue, on neuroprotection after the transient forebrain ischemia were investigated in Sprague-Dawely rats. Expressions of cFos, FosB and BDNF protein in the hippocampus and cortex were observed at 2 hrs and 48 hrs after transient forebrain ischemia by immunohis- tochemistry and ELISA technique. Results : Expression of cFos protein was increased slightly in the hippocampus and cortex at 2 hrs after transient forebrain ischemia, but FosB protein was increased highly comparing to cFos protein. However, pretreatment with folium Artemisiae Argyi or moxa tar' herbal acupuncture on $GV_{20}$ significantly increased expression of cFos protein and significantly decreased expression of FosB protein compared to control group, respectively. These features were observed in the motor cortex and retrosplenial granular cortex as well as the hippocampus. Also, pretreatment with folium Artemisiae Argyi and moxa tar' herbal acupuncture on$GV_{20}$ significantly increased the expression of BDNF protein in the hippocampus and the cortex compared to control group at 48 hrs after transient forebrain ischemia, respectively. Conclusions : These results suggest that pretreatment with folium Artemisiae Argyi or moxa tar' herbal acupuncture on $GV_{20}$ has neuroprotective effect on transient forebrain ischemia and theherbal acupuncture on $GV_{20}$ may be related to antioxidative function.