• 한국임상수의학회지
• /
• 제15권1호
• /
• pp.151-155
• /
• 1998

Abomasal motility was observed by needling to acupoints for 20 min. The acupoints used were guan yuan yurt da chang yurt dei yup pi yurt and hou hoi. The acupoint which showed the increase of the largest wave type was pi yu and the increase of wave type was observed 20 minutes after needling in hou hoi and dei yu acupoint. But there was no effect on abomasal motility after needling to guan yuan yu and da chang yu. On the other hands change in amplitude of the abomasal contraction after needling to these acupoints was not abserved. These results indicate that stimulation to pi yu acupoint would be the most useful to increase the abomasal motility.

• 대한약학회:학술대회논문집
• /
• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
• /
• pp.325.1-325.1
• /
• 2002

Cell motility plays important physiological roles in embryogenesis. immune defense. wound healing. and metastasis of tumor cells. Cell motility of normal cells is tightly regulated. while tumor cell motility is aberrantly regulated or autoregulated. Autotaxin (ATX) is a 125-kDa glycoprotein. originally isolated from the conditioned medium of human melanoma A2058 cells. ATX stimulates random (chemokinetic) and directed (chemotactic) motility of human tumor cells at high picomolar to low nanomolar concentrations. (omitted)

• 한국양식학회지
• /
• 제13권3호
• /
• pp.187-191
• /
• 2000

삼투질농도가 감성돔(Acanthopagrus schlegeli) 정자의 운동성에 미치는 영향을 연구하였다. 감성돔 정자는 정장과 등장인 삼투질농도에서 운동성이 억제되었으나, 전해질(NaCl, KCl, $CaCl_2$, $MgCl_2$) 및 비전해질(mannitol, glucose, fructose, sucrose) 희석액의 삼투질농도가 증가할 때, 운동성을 획득하였다. 희석액의 삼투질농도에 의한 정자운동지수(SMI)의 변화는 포물선을 그렸다 모든 희석액에서 SMI는 해수의 삼투질농도와 유사한 약 1,000 mOsm/kg에서 가장 높았고 그 이상에서는 다시 낮아졌다. 비록 정자의 운동성이 희석액의 삼투질농도에 의해 유발되고 해수와 비슷한 농도의 고장인 희석 액에서 SMI가 가장 높았지만, 고장이나 저장의 희석액에 정자를 노출시키는 것은 정자의 운동성 감소를 유발하였고 생존에 유해하였다.

• 대한의생명과학회지
• /
• 제23권4호
• /
• pp.406-410
• /
• 2017

Curcumin is known as a natural antioxidant, decreasing oxidative stress in animal cells. Generally, oxidative stress induces reactive oxygen species in sperm and leads to decreased sperm characteristics in pigs. Therefore, this study investigated the influence of curcumin on sperm motility, viability, mitochondrial activity and plasma membrane integrity in pigs. Curcumin (0, 5 and $10{\mu}M$) was treated in boar semen, which were incubated for 9 hours in $37^{\circ}C$. Then, motility, viability, mitochondrial activity, plasma membrane integrity of sperm was analyzed every 3 hours. In the results, sperm motility was significantly increased by $5{\mu}M$ curcumin after 3 and 9 hours after incubation, and viability was significantly higher in $5{\mu}M$ curcumin treatment at 3 hours (P<0.05). Similarly, sperm mitochondrial activity and plasma membrane integrity were significantly increased by $5{\mu}M$ curcumin at 3, 6 and 9 hours after incubation (P<0.05). There results suggest that curcumin improve sperm characteristics such as motility, viability, mitochondrial activity, and plasma membrane integrity, and may exert a positive effect on sperm fertility in pigs.

• Journal of Pharmaceutical Investigation
• /
• 제12권3호
• /
• pp.93-99
• /
• 1982

The effects of erythrosine on motility of frog heart, rabbit duodenum and uterus isolated, and on mice intestinal motility and voluntary activity were investigated. The effect of erythrosine $2.3{\times}10^{-5}M$ on isolated frog heart showed a slight decrease of the amplitude of motility, and the heart motility stopped in $3.5{\times}10^{-4}M$. With the administration of erythrosine $3.4{\times}10^{-4}M$, the isolated rabbit duodenum showed a remarkable contraction and this effect was inhibited by atropine $1.4{\times}10^{-7}M$. The administration of erythrosine $2.3{\times}10^{-3}M$, produced a contractile effect on the isolated rabbit uterus, and the motility of $6.9{\times}10^{-3}M$ started to increase in contractions at first and finally stopped, keeping in continuous contractions. The effects of erythrosine 0.5, 1.0, 10, and 20mg/kg on mice intestinal motility were not significantly different from this of the normal control. With 20 and 40mg/kg of erythrosine, the effects on voluntary activity showed the decrease of 21 and 58% respectively, and voluntary activity of the mice pretreated with erythrosine 20 and 40mg/kg, induced by C. N. B. 30mg/kg showed the decrease of 57 and 78% respectively in contrast with the normal control group.

• Environmental Analysis Health and Toxicology
• /
• 제19권2호
• /
• pp.177-182
• /
• 2004

Alcohol consumption and exposure to endocrine disruptors and industrial solvents have been implicated in impaired spermatogenesis, increase in the incidence of malformed sperm and decrease in the percentage of moving sperm. The aim of this study was to determine and compare the direct effects of some organic solvents(bisphenol A; BPA, dibutyl phthalate; DBP, formaldehyde; HCHO, dimethylsulphoxide; DMSO, ethanol) on mucus penetration distance, motility and survival rate of human sperm in vitro. Semen samples from 3 health subjects were prepared using swim-up method and 0.0005-0.5% organic solvents were added to the test medium. BPA, DBP, HCHO and DMSO produced significant decreases in the motility and survival rate with a different potency. The most potent inhibition of mucus penetration distance, motility and survival rate was observed after exposure to HCHO. A concentration of 0.0005% HCHO significantly inhibited sperm motility. When ethanol m.: added directly to sperm, at concentrations equivalent to that in serum after heavy drinking, these damaging effects were lowest compared with other solvents. Present study shows that each compound has different toxic potency to human sperm and we need special caution for the use of HCHO.

• 대한한방내과학회지
• /
• 제39권2호
• /
• pp.201-208
• /
• 2018

Objectives: This is a case report about the effect of Korean medicine on blepharoptosis and ocular motility disorders that occur with thalamus, midbrain, and cerebellum infarctions. Methods: The patient was treated using Korean medicine such as acupuncture, moxibustion, and herbal medicine (Boyanghwano-tang-gamibang). The change of blepharoptosis was evaluated by measurement of palpebral fissure width (PFW), marginal reflex distance-1 (MRD1), and marginal reflex distance-2 (MRD2). The change inocular motility disorders was evaluated by comparison using photographs of the extraocular movements of the patient. We used the Numeric Rating Scale-11 (NRS-11) of diplopia and dizziness to evaluate the effectiveness of treatment. Results: After treatment, blepharoptosis and ocular motility disorders were improved. The NRS-11 score of dizziness decreased from 10 to 7, and diplopia disappeared after Korean medicine treatment. Conclusions: According to this study, Korean medicine can be effective for treating blepharoptosis and ocular motility disorders in thalamus, midbrain, and cerebellum infarctions.

• 한국소음진동공학회:학술대회논문집
• /
• 한국소음진동공학회 2006년도 춘계학술대회논문집
• /
• pp.759-763
• /
• 2006

The World Health Organization(WHO) has recommended population of sleep disturbance as one of the environmental health indicators. But the percentage of respondents who felt highly sleep disturbed, that is, %HSD can???thave application to sleep disturbance from instantaneous noise. Therefore, this study has been carried out to present the technique for assessing sleep disturbance on instantaneous noise quantitatively. The study of sleep disturbance on night time instantaneous railway noise has been undertaken. Noise monitor has been in operation from 22 hours to 7 hours during 6 nights at 12 locations. To assess instantaneous noise induced sleep disturbance, it was decided to measure body movement by actiwatch. %motility was used as indicators of sleep disturbance. %motility is the expected value of probability of motility value during 7 epochs (105s) of any noise event. The measures of instantaneous motility have been related to measures of instantaneous railway noise events. The relationship shows that %motility is a good predictor for assessing sleep disturbance and Korean is more sensitive to noise than European although the railway noise have been considered in this study. This study can be extended to assessing long-term sleep disturbance and give a guideline far policy decision.

• 한국임상수의학회지
• /
• 제19권4호
• /
• pp.397-400
• /
• 2002

본 연구는 침술이 개의 위 운동성에 미치는 효과에 관하여 알아보기 위하여 실시하였다. 건강한 잡종견 6두의 유문부 근층에 전극을 장착한 후 위근전도를 (electrogastromyograms, EGMG) 기록하여 위 운동성을 평가하였다. 침술은 ST-36, ST-40, ST-41, ST-42, ST-45, BL-21 및 CV-12 혈 위에 실시하였다. ST-36 및 BL-21 혈 위에 침술을 실시한 결과 위 운동성이 증가되었으며, CV-12 혈 위에서는 위 운동성이 감소되었다. 그러나 ST-40, ST-41, ST-42 및 ST-45 혈위의 침술은 위 운동성에 영향을 미치지 않았다

• Clinical and Experimental Reproductive Medicine
• /
• 제26권1호
• /
• pp.97-101
• /
• 1999

Male genital tract inflammatory conditions may be associated with unexplained infertility. The presence of cytokine such as tumor necrosis factor-alpha (TNF-${\alpha}$) was reported in the semen of infertile men. However, the effect of these cytokines on human sperm function is still unclear. The purpose of this study was to investigate the in-vitro effects of TNF-alpha on human sperm motility with computer assisted sperm analysis. Washed sperm from 16 normal men were incubated without and with TNF-${\alpha}$ (0.1, 10, 1000 ng/ml). The changes of parameters of sperm motility were recorded at different time intervals (0, 5, 24 hour). There was no significant change of parameters of sperm motility in the incubation with TNF-${\alpha}$. It is suggested that TNF-${\alpha}$ alone does not interfere with the sperm motility and more studies are needed.