• Title/Summary/Keyword: Morpholoy

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THE EFFECT OF SUPEROXIDE DISMUTASE ON EXPERIMENTAL GINGIVITIS AND ACTIVITY OF 3T3 FIBROBLAST (Superoxide Dismutase가 백서의 실험적 치은염과 3T3 섬유모 세포의 활성에 미치는 영향)

  • Kim, Yoon-Seong;Yoo, Hyung-Keun;Kang, Hyun-Ku;Shin, Hyung-Shik
    • Journal of Periodontal and Implant Science
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    • v.25 no.2
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    • pp.222-238
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    • 1995
  • Inflammatory cells may produce active species of oxygen in antimicrobial defense. While such species can directly damage surrounding tissue, their major secondary role may be to mediate important components of the inflammatory response. Superoxide dismutase, antioxidant, have significant anti-inflammatory properties in rheumatoid arthritis, ischemic tissue injury and gastrointestinal disease. Increased oxidative product formation diseases. And superoxide dismutase produced by Porphyromonas Gingivalis is resistant to killing by polymorphonuclear leukocyte. The purpose of this study was to investigate on the effects of superoxide dismutase in 3T3 fibroblast and in experimental gingivitis in the rats. The effect of superoxide dismutase(SOD) to cell morphology and cell activity was measured in cultured mouse 3T3 fibroblast. After experimental gingivitis were induced by lipopolysaccharide(LPb) and bovine serum albumin(BSA), injection of SOD were done. WBC count and histologic findings were observed at 1, 2, 3, and 7 days. The results were as follows; 1. There was a little difference between LPS treated groups and SOD treated groups in 3T3 fibroblast morpholoy. 2. There was no difference between only SOD treated groups (except SOD 150U at 3days) and control in 3T3 fibroblast activity. 3. LPS $0.5{\mu}g/ml$ and SOD treated groups (except 150U) had decreased 3T3 fibroblast activity and no significant difference at 3 days. 4. LPS $5.0{\mu}g/ml$ and SOD treated groups were significantly increased cell activity of 3T3 fibroblast than control group at 1 day(P<0.05). 5. In LPS induced gingivitis, the number of leukocytes in SOD treated was significantly decreased than in saline treated at 1 day(P<0.05). 6. In histopathologic findings of LPS or BSA induced gingivitis, inflammatorycell infiltration in SOD treated groups were less than in saline treated group at 1, 2 and 3 days.

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The Study on the Biomechanical Body Segment Parameters of Korean Adults with References to Sasang Constitutional Medicine (한국인 신체분절에 관한 사상의학적 연구)

  • Lee, Eui-ju;Lee, Jae-koo;Kim, Jeong-yun;Song, Jeong-mo
    • Journal of Sasang Constitutional Medicine
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    • v.10 no.1
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    • pp.143-160
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    • 1998
  • PURPOSE This studied the biomechanical body segment parameters of Korean adults with reference to Sasang Constitutional Medicine(SCM). We anlyzed the characteristics of Sasang constitution through Body Measurement, Immersion Method, and Reaction Board Method. SUBJECT Subjects were 72 persons. There were made 49 and Female 23. Mean age was . And There were Taeumin 30, Soyangin 17, and Soeumin 25. METHOD The items of Body Measurement were 51. Limbs were measured right side. Volume was gained with Immersion Method and Weight was calculated with the density equation for limbs from Drills and Contini. Center of Mass was gained with Reaction Board Method. RESULT 1. In Body Measurement there were the significant differences with each constitution of man's circumference. 2. In Volume there were the significant differences between Taeumin and Soeumin in mand. And the volume rate of head and neck, hand, and foot was the lowest in Taeumin, but the highest in Soeumin. 3. In center of mass Soyangin was higher than others.

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Hydrophilic Modification of Porous Polyvinylidene Fluoride Membrane by Pre-irradiating Electron Beam (전자빔 전조사를 이용한 Polyvinylidene Fluoride 다공막의 친수화 개질)

  • Choi, Yong-Jin;Lee, Sung-Won;Seo, Bong-Kuk;Kim, Min
    • Membrane Journal
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    • v.21 no.2
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    • pp.118-126
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    • 2011
  • A method of light pre-irradiation, one of methods modifying hydrophobic surface to hydrophilic surface in a membrane, was proposed to overcome the drawback of previous methods such as blending, chemical treatment and post-irradiation, Process of membrane preparation in the study was comprised of 4 parts as follows: firstly process of precursor preparation to introduce hydrophilic nature under atmosphere and aqueous vapor by irradiating electron beam (EB), secondly process of dope solution preparation to cast on non-woven fabrics, thirdly process of casting to prepare membrane and finally process of coagulation in non-solvent to form porous structure. The merit of this method might show simple process as well as homogenous modification compared to previous methods. To carry it out, precursor was prepared by irradiating EB to powder PVDF at 75~125 K Gray dose. Precursor prepared was analyzed by FTIR, EDS and DSC to confirm the introduction of hydrophilic function and its mechanism. From their results, it was inferred I conformed that hydrophilic function was hydroxy1 and it was introduced by dehydrozenation. Hydrophilicity of membranes prepared was evaluated by contact angle (pristine PVDF : $62^{\circ}$, 125 K Gray-PVDF$13^{\circ}$). Porosity was evaluated by mercury intrusion method, simultaneously morpholoy and surface pore size were observed by SEM phothographs. The result showed the trend that more dose of EB led to smaller pore size and to lower porosity (pristine PVDF : 82%, 125 K Gray-PVDF : 63%). Trend of water permeability was similar to result above (pristine PVDF : 892 LMH, 125 K Gray-PVDF : 355 LMH).