• 제목/요약/키워드: Morphological variables

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Formation and Characterization of Casein Phosphopeptide/Chitosan Oligosaccharide NanoComplex (케이신 포스포펩티드/키토올리고당 나노 복합체 형성과 특성 연구)

  • Baek, Yun-Seo;Ha, Ho-Kyung;Lee, Ji-Hong;Lee, Mee-Ryung;Lee, Won-Jae
    • Journal of Dairy Science and Biotechnology
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    • v.36 no.3
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    • pp.164-170
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    • 2018
  • The objectives of this study were to manufacture casein phosphopeptide (CPP)/chitosan oligosaccharide (CSO) nanocomplexes and to investigate the impacts of manufacturing variables, such as CPP concentration and pH, on their morphological and physicochemical characteristics. Transmission electron microscopy (TEM) and particle size analysis were used to assess the morphological and physicochemical properties of the CPP/CSO nano-complexes, respectively. Based on the images obtained by TEM, the spherical shapes of the CPP/CSO nanocomplexes ranged from 50 to 150 nm. As the concentration of CPP was increased and the pH was decreased, the average particle size of the nanocomplexes significantly (p<0.05) increased. The CPP/CSO nanocomplexes had a highly uniform distribution with a polydispersity index value of less than 0.3. In addition, they had a negative surface charge with a zeta-potential value between -17 and -26 mV. The CPP/CSO nanocomplexes showed good stability during the freeze-drying process. In conclusion, CPP/CSO nanocomplexes were successfully manufactured, and the CPP concentration and pH were found to be key factors that affected their morphological and physicochemical properties.

Morphological and Hemodynamic Parameters for Middle Cerebral Artery Bifurcation Aneurysm Rupture Risk Assessment

  • Qin, Hao;Yang, Qixia;Zhuang, Qiang;Long, Jianwu;Yang, Fan;Zhang, Hongqi
    • Journal of Korean Neurosurgical Society
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    • v.60 no.5
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    • pp.504-510
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    • 2017
  • Objective : To investigate the morphological and hemodynamic parameters associated with middle cerebral artery (MCA) bifurcation aneurysm rupture. Methods : A retrospective study of 67 consecutive patients was carried out based on 3D digital subtraction angiography data. Morphological and hemodynamic parameters including aneurysm size parameters (dome width, height, and perpendicular height), longest dimension from the aneurysm neck to the dome tip, neck width, aneurysm area, aspect ratio, Longest dimension from the aneurysm neck to the dome tip (Dmax) to dome width, and height-width, Bottleneck factor, as well as wall shear stress (WSS), low WSS area (LSA), percentage of LSA (LSA%) and energy loss (EL) were estimated. Parameters between ruptured and un-ruptured groups were analyzed. Receiver operating characteristics were generated to check prediction performance of all significant variables. Results : Sixty-seven patients with MCA bifurcation aneurysm were included (31 unruptured, 36 ruptured). Dmax (p=0.008) was greater in ruptured group than that in un-ruptured group. D/W (p<0.001) and the percentage of the low WSS area ($0.09{\pm}0.13$ vs. $0.01{\pm}0.03$, p<0.001) were also greater in the ruptured group. Moreover, the EL in ruptured group was higher than that in unruptured group ($6.39{\pm}5.04$ vs. $1.53{\pm}0.86$, p<0.001). Multivariate regression analysis suggested D/W and EL were significant predictors of rupture of MCA bifurcation aneurysms. Correlation analyses revealed the D/W value was positively associated with the EL (R=0.442, p<0.01). Conclusion : D/W and EL might be the most two favorable factors to predict rupture risk of MCA bifurcation aneurysms.

Measurements of $T_1$-and $T_2$-relaxation Time Changes According to the Morphological Characteristics of Gold Nanoparticles (GNPs) (금 나노 입자의 형태적 특성에 따른 $T_1$, $T_2$ 이완 시간의 변화 측정)

  • Jang, M.Y.;Han, Y.H.;Mun, C.W.
    • Investigative Magnetic Resonance Imaging
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    • v.15 no.1
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    • pp.48-56
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    • 2011
  • Purpose : The aim of this study is to measure the typical MR variables such as $T_1$- and $T_2$-relaxation times according to morphological characteristics of gold nanopartides as a preliminary study to perform theragnosis using local heating by gold nanopartides. Materials and Methods : Two types of gold nanoparticles were used. Spheres were synthesized by various methods and stirring speed. Rods were synthesized by adding various concentrations of sphere nanopartides. Gold nanopartides were mixed with 2% agarose gel at 1:1 ratio and then signals were acquired using a 1.5T MRI. For the measurements of $T_1$-and $T_2$-relaxation times, TR and TE were varied, respectively. The results were acquired through $T_1$ and $T_2$ curves based on the intensities of MR image using self-developed software. And Statistical analysis was performed. Results : $T_1$ times were measured 1.86 sec and 2.08 sec for sphere and rod, respectively. On the other hands, $T_2$ times were measured 57 ms and 35.45 ms for sphere and rod. Conclusion : The changes of the MR variables according to the morphological characteristics of the gold nanopartides were confirmed. Optimal MR imaging conditions can be obtained by choosing proper TR and TE according to the type of nanoparticles.

Use of the Quantitatively Transformed Field Soil Structure Description of the US National Pedon Characterization Database to Improve Soil Pedotransfer Function

  • Yoon, Sung-Won;Gimenez, Daniel;Nemes, Attila;Chun, Hyen-Chung;Zhang, Yong-Seon;Sonn, Yeon-Kyu;Kang, Seong-Soo;Kim, Myung-Sook;Kim, Yoo-Hak;Ha, Sang-Keun
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.5
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    • pp.944-958
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    • 2011
  • Soil hydraulic properties such as hydraulic conductivity or water retention which are costly to measure can be indirectly generated by soil pedotransfer function (PTF) using easily obtainable soil data. The field soil structure description which is routinely recorded could also be used in PTF as an input to reduce the uncertainty. The purposes of this study were to use qualitative morphological soil structure descriptions and soil structural index into PTF and to evaluate their contribution in the prediction of soil hydraulic properties. We transformed categorical morphological descriptions of soil structure into quantitative values using categorical principal component analysis (CATPCA). This approach was tested with a large data set from the US National Pedon Characterization database with the aid of a categorical regression tree analysis. Six different PTFs were used to predict the saturated hydraulic conductivity and those results were averaged to quantify the uncertainty. Quantified morphological description was successively used in multiple linear regression approach to predict the averaged ensemble saturated conductivity. The selected stepwise regression model with only the transformed morphological variables and structural index as predictors predicted the $K_{sat}$ with $r^2$ = 0.48 (p = 0.018), indicating the feasibility of CATPCA approach. In a regression tree analysis, soil structure index and soil texture turned out to be important factors in the prediction of the hydraulic properties. Among structural descriptions size class turned out to be an important grouping parameter in the regression tree. Bulk density, clay content, W33 and structural index explained clusters selected by a two step clustering technique, implying the morphologically described soil structural features are closely related to soil physical as well as hydraulic properties. Although this study provided relatively new method which related soil structure description to soil structure index, the same approach should be tested using a datasets containing the actual measurement of hydraulic properties. More insight on the predictive power of soil structure index to estimate hydraulic properties would be achieved by considering measured the saturated hydraulic conductivity and the soil water retention.

A Study on Somatotype Classification of Muscular Men's Lower Body (근육형 남성의 하반신 체형분류에 관한 연구)

  • Jeong, Hye-Jin;Kim, So-Ra
    • Journal of the Ergonomics Society of Korea
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    • v.28 no.1
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    • pp.21-27
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    • 2009
  • The purpose of this research is to understand the physiological characteristics of muscular men between the ages of 20 and 34 years who are distinct from the general population due to their muscular development, and to categorize them according to upper body somatotypes. This research was conducted in order to provide basic data necessary for developing clothing products for muscular men. The research method and results were as follows: 1. The study carried out factor analysis with the body measuring value of 168 muscular men according to the body classification method of Sheldon and Heath-Carter. The study materialized muscular men's lower body types statistically by carrying out cluster analysis, regarding scores of each factor extracted from the factor analysis as an independent variable. The study also carried out discriminant analysis with the results of cluster analysis classified so that morphological characters of each type were remarkably distinguished. 2. As the results of factor analysis, the study set up number of factors as three. Factor 1 occupied 38.149% of the total variables as a size factor of the lower body. Factor 2 occupied 20.417% of the total variables as a height and length factor of the lower body. Factor 3 occupied 8.466% of the total variables as a length factor of the hip. 3. The study classified the lower body type into three types and the characteristics by each type were as follows. Type 1 was a group with the best developed muscle in the lower of the body, considering that a size of their lower bodies was the largest. Type 2 was well-balanced muscular males though a size of the lower body was smaller than other types. This type didn't have fatness of the abdomen and large hips. Type 3 was a body type that the length from the waist to the hip was long. 4. As the results of carrying out discriminant analysis to distinguish muscular men's lower body types, the discriminant accuracy was 86.3% over all in the lower bodies.

Research for fabricating micro-size PMMA beads using Electro-hydrodynamic process (Electro-hydrodynamic 프로세스를 이용한 PMMA 마이크로 비드 제조방법에 대한 연구)

  • Park, Jong-Ha;Lee, Jun-Hee;Kim, Wan-Doo
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.1509-1514
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    • 2008
  • To fabricate microsized poly(methyl methacrylate)(PMMA) beads of uniform size and density on poly(ethylene terephthalate) (PET) fis, we introduce an electro spraying technique that uses a target electrode applied with an ac electric fid. Using the apparatus and various material properties, we could obtain uniform size PMMA beads which were deposited on the thin PET film. The optical properties, transmittance and light diffusivity of the fis electro sprayed with the PMMA were characterized. The results show that the sprayed beads appear to act as a good optical diffuser, like microlenses. To understand the effect of process variables, applied field conditions and rheological properties, the morphological pictures of the deposited particles were investigated through the optical and scanning electron microscope.

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An Electronic System in Automatic Refracto-Keratometer (자동 시각 굴절력 곡률계의 전자 부문 시스템)

  • Seong, Won;Ryu, Gang-Min;Park, Jong-Won
    • Journal of KIISE:Computing Practices and Letters
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    • v.8 no.6
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    • pp.669-678
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    • 2002
  • Currently, the domestic interests on the development of eyesight related measuring instruments are being increased. So we are developing such an electronic system of Refracto-keratometer, which contains a software and a hardware both. If this system could inform the examiner of the precise eyesight measuring result from the treatment of the image of optical system, then potentially the number of missed measuring results could be reduced. Our electronic system has been developed from the two areas divided into a software and a hardware. The software area was focused on the more exact eyesight measuring results, using morphological filtering methods and gray-leveled signal enhancing techniques. The hardware area is performing the same functions as the existing other systems. Besides, it provides the embedded software with free variables which could reduce the developing duration sharply as well as enlarge many kinds of application-extensions. Therefore, this electronic system has made effective eyesight measurement possible as the result of reducing the differences applied to sophisticated eyesight measurement.

Evaluation of Stage of Liver Fibrosis by Ultrasonography : Based on Pathologic Results of Biopsy (초음파검사를 통한 간 섬유화 병기단계 평가 : 조직검사결과 기준으로)

  • An, Hyun;Lee, Hyo-Yeong;Im, In Chul
    • Journal of the Korean Society of Radiology
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    • v.13 no.4
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    • pp.547-555
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    • 2019
  • The purpose of this study was to evaluate the usefulness of routine liver ultrasonography on the basis of the scoring system according to the morphological parameters of liver ultrasound images and the histopathological results of liver biopsy. The morphological parameters of the liver through ultrasonography were divided into liver surface, liver edge and liver parenchyma. Pathologic results of liver biopsy were classified as mild fibrosis(F1), significant fibrosis(F2), severe fibrosis(F3), and cirrhosis(F4). In conclusion, routine ultrasound examination showed a sensitive predictive factor for fibrosis with mild fibrosis (F1) to severe fibrosis (F3) were liver edge>liver parenchyma>liver surface. However, the predictive factors for detecting cirrhosis (F4) were liver parenchyma>liver surface>liver edge. The use of three variable combinations rather than individual variables in routine ultrasonography may be useful in evaluating the degree and progress of liver fibrosis.

Korean Standard Classification of Functioning, Disability and Health (KCF) Code Linking on Natural Language with Extract Algorithm (자연어 알고리즘을 활용한 한국표준건강분류(KCF) 코드 검색)

  • Nyeon-Sik Choi;Ju-Min Song
    • Journal of the Korean Society of Physical Medicine
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    • v.18 no.1
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    • pp.77-86
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    • 2023
  • PURPOSE: This study developed an experimental algorithm, which is similar or identical to semantic linking for KCF codes, even if it converted existing semantic code linking methods to morphological code extraction methods. The purpose of this study was to verify the applicability of the system. METHODS: An experimental algorithm was developed as a morphological extraction method using code-specific words in the KCF code descriptions. The algorithm was designed in five stages that extracted KCF code using natural language paragraphs. For verification, 80 clinical natural language experimental cases were defined. Data acquisition for the study was conducted with the deliberation and approval of the bioethics committee of the relevant institution. Each case was linked by experts and was extracted through the System. The linking accuracy index model was used to compare the KCF code linking by experts with those extracted from the system. RESULTS: The accuracy was checked using the linking accuracy index model for each case. The analysis was divided into five sections using the accuracy range. The section with less than 25% was compared; the first experimental accuracy was 61.24%. In the second, the accuracy was 42.50%. The accuracy was improved to 30.59% in the section by only a weight adjustment. The accuracy can be improved by adjusting several independent variables applied to the system. CONCLUSION: This paper suggested and verified a way to easily extract and utilize KCF codes even if they are not experts. KCF requires the system for utilization, and additional study will be needed.

Three-dimensional evaluation of the mandibular condyle in adults with various skeletal patterns

  • Ahmed Maher Mohsen;Junjie Ye;Akram Al-Nasri;Catherine Chu;Wei-Bing Zhang;Lin-Wang
    • The korean journal of orthodontics
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    • v.53 no.2
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    • pp.67-76
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    • 2023
  • Objective: Morphometric and morphological evaluation of the mandibular condyle in adults and to identify its correlation with skeletal malocclusion patterns. Methods: Cone-beam computed tomography scans of 135 adult patients were used in this study and classified into groups according to four criteria: (1) sex (male and female); (2) sagittal skeletal discrepancy (Class I, Class II, and Class III); (3) vertical skeletal discrepancy (hyperdivergent, normodivergent, and hypodivergent); and age (group 1 ≤ 20 years, 21 ≤ group 2 < 30, and group 3 ≥ 30 years). The morphometrical variables were mandibular condyle height and width, and the morphological variable was the mandibular condyle shape in coronal and sagittal sections. Three-dimensional standard tessellation language files were created using itk-snap (open-source software), and measurements were performed using Meshmixer (open-source software). Results: The mandibular condyle height was significantly greater (p < 0.05) in patients with class III malocclusion than in those with class I or II malocclusion; the mandibular condyle width was not significantly different among different sexes, age groups, and sagittal and vertical malocclusions. There were no statistical associations between various mandibular condyle shapes and the sexes, age groups, and skeletal malocclusions. Conclusions: The condylar height was greatest in patients with class III malocclusion. The condylar height and width were greater among males than in females. The mandibular condyle shapes observed in sagittal and coronal sections did not affect the skeletal malocclusion patterns.