• 제목/요약/키워드: Morphological Change

검색결과 872건 처리시간 0.029초

Morphological remodeling in mouse vagina due to hormonal hypersecretion

  • Oh, Min-Gee;Kim, Sang-Hwan
    • 한국동물생명공학회지
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    • 제37권1호
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    • pp.42-47
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    • 2022
  • This study aimed to determine whether hormonal hypersecretion could cause morphological problems in the mouse vagina and affect the ovaries and nearby extra uterine organs. All mice were synchronized to estrus before the experiment. Then human chorionic gonadotropin (hCG), progesterone, and testosterone were continuously administered for about 6 days to maintain hormone hypersecretion, and then morphological changes were analyzed, and Matrix metalloproteinases (MMPs) activity and Casp-3 expression were evaluated. As a result of the analysis, in the case of hCG, the morphological change did not show a significant difference from the vagina of normal estrus. In the case of progesterone, changes were observed in the mucosa zone and basal membrane, and it was confirmed that the activity of MMPs was increased in squamous epithelium cells. On the other hand, in the case of testosterone, overall changes in vaginal tissues were observed, and MMPs activity was increased to a very high level in all sections. The expression of Casp-3 was also the highest compared to other groups. Therefore, as a result of this study, it is thought that hormone hypersecretion affects the morphological changes of the vagina other than the ovaries and uterus and induces the activity of MMPs to cause morphological degeneration of tissues.

Inhibitory effects of honokiol on LPS and PMA-induced cellular responses of macrophages and monocytes

  • Lee, Sang-Yeol;Cho, Jae-Youl
    • BMB Reports
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    • 제42권9호
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    • pp.574-579
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    • 2009
  • The regulatory effects of honokiol on the cellular responses of macrophages and monocytes were evaluated. Specifically, we investigated the effects of honokiol with respect to lipopolysaccharide (LPS)-induced cytotoxicity, LPS- or phorbol-12-myristate-13-acetate (PMA)-mediated morphological changes, and relevant events (FITC-dextran-induced phagocytic uptake). Honokiol blocked the LPS-induced cytotoxicity of RAW264.7 cells in a dose-dependent manner. In addition, honokiol appeared to block the production of cytotoxic cytokines such as interleukin (IL)-$1{\beta}$ and tumor necrosis factor (TNF)-$\alpha$, nitric oxide (NO), and reactive oxygen species (ROS). Moreover, honokiol strongly prevented the morphological changes in RAW 264.7 and U937 cells that were induced by LPS and PMA. The surface levels of marker proteins, which are up-regulated under the morphological changes of RAW264.7 and U937 cells, were also diminished. The data presented here strongly suggest that the honokiol modulates various cellular responses managed by macrophages and monocytes.

Codium fragile subsp. fragile (Suringar) Hariot in Tunisia: morphological data and status of knowledge

  • Cherif, Wafa;Ktari, Leila;Bour, Monia El;Boudabous, Abdellatif;Grignon-Dubois, Micheline
    • ALGAE
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    • 제31권2호
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    • pp.129-136
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    • 2016
  • The Mediterranean Sea is currently facing dramatic changes and threats, including change in native species and accidental introductions. The introduced green alga Codium fragile subsp. fragile (Suringar) Hariot influences diversity and community structure in some parts of the world. This paper documents the distribution of this species in Tunisia and provides a morphological description of C. fragile subsp. fragile in Northern Tunisia. Results confirm the identity of Tunisian specimens as the invasive subspecies C. fragile subsp. fragile. This is the first morphological characterization of this subspecies in Tunisia.

NB 모델을 이용한 형태소 복원 (Morpheme Recovery Based on Naïve Bayes Model)

  • 김재훈;전길호
    • 정보처리학회논문지B
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    • 제19B권3호
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    • pp.195-200
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    • 2012
  • 한국어는 교착어이어서 형태소 분석 없이 품사 부착이 어려울 뿐 아니라 형태소를 분석할 때 다양한 어형 변화가 복원되어야 한다. 이것은 한국어 형태소 분석의 고질적인 문제 중 하나이며, 주로 규칙을 이용해서 해결한다. 규칙을 이용할 경우 주어진 문맥에 가장 적합한 복원을 어려워 여러 형태의 모호성을 생성하며, 이는 품사 부착에 의해서 해결된다. 본 논문에서는 이 문제를 기계학습 방법(Na$\ddot{i}$ve Bayes 모델)을 이용하여 해결한다. 기계학습 모델의 입력 자질은 어형 변화가 발생하는 주변 음절이며 출력 범주는 복원된 음절이다. ETRI 구문 말뭉치를 이용한 실험에서 제안된 형태소 복원 모델을 사용한 형태소 단위의 품사 부착 성능은 97.5%의 $F_1$점수를 보였으며 이 모델이 형태소 복원에 매우 유용함을 알 수 있었다.

홍수에 의한 하도변형을 고려한 물리서식처 모의 (Physical Habitat Simulation Considering Stream Morphology Change due to Flood)

  • 이성진;김승기;최성욱
    • 대한토목학회논문집
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    • 제34권3호
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    • pp.805-812
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    • 2014
  • 본 연구에서는 하상변동의 고려가 물리서식처 모의에 미치는 영향을 검토하였다. 이를 위해 수리 및 이동상 계산은 CCHE2D 모형을 이용하였으며 서식처 적합도 곡선을 사용하여 서식처 평가를 실시하였다. 적용구간은 달천 유역 괴산댐 하류 수전교에서 대수보까지 약 2.5km 구간이며, 2006년 7월 홍수기 시 실측된 유량 및 수위자료를 이용하여 이동상 모의를 수행하였다. 수치모형의 검증은 실측된 수위와의 비교를 통해 수행되었으며 하상변동의 검증은 실시 하지 않았다. 물리서식처 분석은 우점종인 성어기 피라미를 대상으로 실시하였다. 고정상과 이동상 조건에서 각각 갈수량, 저수량, 평수량, 풍수량의 유랑조건에 대한 복합서식처 적합도 지수 분포를 모의하고 가중가용면적을 산정하였다. 모의 결과, 이동상 조건에서 모의구간의 상류 및 만곡부에서 복합 서식처 적합도지수가 상승하는 결과를 확인하였다. 또한 가중가용면적은 이동상 고려 시 5.4~11.3%정도 증가하는 것을 확인하였다.

A Study on the Wave Type and the Damage of Hair according to Water content when Heat permanent is treated - Focus on Damaged Hair -

  • Lee, Soon-Hee;Choi, Jung-Myung
    • 패션비즈니스
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    • 제12권6호
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    • pp.11-22
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    • 2008
  • The goal of this study is to provide beauticians with the fundamental material to use effectively heat permanent wave in beauty industry as well as their customer's satisfaction. It carried out an experiment with damaged hair of a woman in her late twenties to investigate the change of physical and morphological characteristics by its water content when performing heat permanent wave. After spreading 0g, 1g, 2g, 3g, and 4g of water on damaged hair respectively, heat permanent wave was treated and the change of hair was observed. The change of physical characteristic was compared through permanent wave form of hair, tensile strength and elongation. The change of morphological characteristic was observed through Scanning Electron Microscope(SEM) and Transmission Electron Microscope(TEM). The result of experiment on the physical specificity revealed that permanent wave form was the most ideal when the water content was 2g, also 3g. Though the materials with much moisture content formed the results were not satisfied. The material with 0g of water content didn't make the wave. In terms of tensile strength and elongation, tensile strength was generally reduced as per the damaged degree of hair. On the contrary, elongation was increased. It observed the changes of morphological characteristic that the damage on hair cuticle was deepen, as its moisture content was decreased, and cuticle's surface was worn away. The observation of fine structure on hair section by transmission electronic microscope also certainly showed the result that damaged hair having experience with chemical treatment had got much damaged to hair cuticle as well as hair cortex. Generally chemical treatment makes hair damaged. Under consideration of this aspect, the ultimate goal of this thesis is to minimize the damage of hair caused by chemical treatment and get the satisfaction on the hair style. According to the result of experiment, the damaged hair whose moisture content was 3g showed the best permanent wave form.

탈색단계별 과산화수소 농도에 따른 모발의 물리.형태적 손상정도 비교 (The Comparison of Physical & Morphological Damage of Hair According to the Bleaching Methods by the $H_2O_2$ Concentration)

  • 이은경;황중덕;김혜정
    • 한국패션뷰티학회지
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    • 제5권1호
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    • pp.71-77
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    • 2007
  • This study attempted to comparative analysis about the physical and morphological damage degrees of hair according to the bleaching methods by $H_2O_2$ concentration. As a result of the changes in the physical characteristics of the hair according to the deceleration operation methods by 3-6-9% and 9% $H_2O_2$ concentration, the intensity of tension considerably decreased but the elongation was increased. And the more the damage of hair, the larger the degree of change. Regarding the method of deceleration operation, the 3-6-9% deceleration operation method was more damaging than the 9% single deceleration operation method. In the change of the characteristics of the form of the hair, the control group of the 5-level deceleration hair generally showed a smooth external appearance and regular and closely overlapped epidermis and undamaged cuticle were observed. But in the 3-6-9% deceleration operation method and 9% single deceleration operation method, damages such as the irregular form of the edge of the epidermis and the unclear boundary between the epidermis occurred.

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Morphological Change of Crosslinked ${\beta}$-Cyclodextrin after Recycling

  • Han, Eun-Mi;Kim, Song-Hee;Kim, Ki-Woo;Kwak, Hae-Soo
    • Journal of Dairy Science and Biotechnology
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    • 제25권1호
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    • pp.9-13
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    • 2007
  • The present study was carried out to examine the effect of crosslinked ${\beta}$-cyclodextrin(${\beta}$-CD) made by adipic acid on cholesterol removal rate and find the structural change after recycling on SEM observation. The size reduction and morphological changes were found during the recycling process and the profound changes were observed at 8th time reuse. After cholesterol removal in milk, the used crosslinked ${\beta}$-CD was washed for cholesterol dissociation and reused. In recycling study, the cholesterol removal rate at first trial was 92.5% in milk, which was mostly same as that using new crosslinked ${\beta}$-CD(92.4%). With repeated 10th reuse of crosslinked ${\beta}$-CD resulted in 81.4% of cholesterol removal in milk. Similar trend was found in cream and cholesterol removal was 91.5% at 1st trial and 83.4% at 10th trial. In both milk and cream samples, the removal rate at 1st reuse was not significantly different from that at 6th reuse(p>0.05). The present study indicated that crosslinked ${\beta}$-CD made by adipic acid resulted in the effective recycling efficiency, especially up to 6th reuse and morphological modifications were not distinguishable up to 8th reuse.

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대두 발아중 오존수 처리가 acid phoshatase 및 배유세포의 형태학적인 변화 (Ozone-water Treatment on the Morphological Changes of Endosperm cell and the activity of Acid Phosphatase during Soybean(Glycine max) Germination)

  • 박홍덕
    • 생명과학회지
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    • 제11권5호
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    • pp.489-495
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    • 2001
  • 대두 발아종 오존수 처리에 의한 배유세포와 산성 인산호효소의 변화에 관해서 전자현미경으로 조사한 결과는 다음과 같다. 산성 인산화효소의 활성은 발달하고 있는 종자 배유의 여러 소기관에 나타났는데, 효소의 활성은 0.5 ppm 오존수를 처리한 후 12시간 배양중에 나타났다. 오존수를 처리한 후 배유가 분화함에 따라 산성 인산화효소의 반응산물은 액포내에 축적되는 것으로 나타나는데, 이것은 산성 인산화효소가 세포간 저장물질의 분해와 이동에 관여하는 것으로 여겨진다.

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올린 도서관 현상설계에서 나타난 근대건축의 공간적 특성에 관한 연구 - 장소적 질서와 형태적 상징을 중심으로 - (A Study on the Spatial Characteristics of Modern Architecture found from the Olin Library Competition - Focused on the Local Order and Morphological symbols -)

  • 임종엽;김윤겸
    • 교육시설 논문지
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    • 제22권4호
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    • pp.15-25
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    • 2015
  • The Olin Library in St. Louis was an important design competition for the United States in the 1950's, the rear of America's modern architecture. The participants of this competition were a variety of representative architects and groups of its time. With the library's functional rationality, the Olin Library competition was legible of the aspects of modern architectural flow. The competition required two demands. The first demand was absolute importance in character definition of place, which was to satisfy the site conditions approached from campus design. Secondly was related to interpretation of morphological symbolism in an architectural matter. The experiments of American modern architecture started to change its ideal goal gradually ; accommodating the altering public's code, at the same time, maintaining the original modern value was the reason to changing the ideal goal. As a turning point, the Olin Library should be understood as an important work, which divulged the value change of architectural interpretation.