• Bulletin of the Korean Chemical Society
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• v.35 no.7
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• pp.2151-2154
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• 2014

• Journal of Korean Society for Atmospheric Environment
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• v.20 no.2
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• pp.175-183
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• 2004

In order to investigate the composition ratio and the emission rate of monoterpenes emitted from coniferous trees during summer, the enclosure chamber experiments were carried out for two tree species (Pinus densiflora and Pinus rigida). The major monoterpenes from the pine trees were $\alpha$-pinene, $\beta$-pinene, myrcene and $\beta$-phellandrene. There was no difference of the composition ratio between two sites for P. densiflora, but the difference was observed for P. rigida. Clearly, the ratio of $\beta$-pinene (26.1 %) for P. rigida was higher than that of $\beta$-phellandrene (12%) at the Gumsung mountain site, but the ratio of $\beta$-phellandrene (22.2%) was higher than that of $\beta$-pinene (9.9%) at the Chiri mountain site. Particularly, the composition ratio of $\beta$-phellandrene was higher than that of $\beta$-pinene for P. densiflora, and the opposite trend was found for P. rigida at the Gumsung mountain site. The characteristics of the composition ratio between two species were similar at the Chiri mountain site. As a result of the emission rate measurements, it was observed that both sites did not show any significant $\beta$ value (slope between emission rate and temperature) and ERs (Standard Emission rate at 3$0^{\circ}C$) difference. However, the $\beta$ value and ERs at the Chiri mountain site were slightly greater than those of Gumsung mountain site for both pine species. P. densiflora (1.703 and 1.971 $\mu\textrm{g}$C/gdw/hr) showed the higher monoterpene ERs than those of P. rigida (0.572 and 0.698 $\mu\textrm{g}$C/gdw/hr) at both sites.

• Journal of the Korean Applied Science and Technology
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• v.29 no.4
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• pp.610-617
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• 2012

Trifoliate orange components consist of several kinds, such as monoterpenes, limonoids, flavonoids, and coumarins. Coumarin derivatives were shown to possess valuable pharmacological properties such as anti-inflammatory and dietary effect. Among them, 7-geranyloxycoumarin 6 is a promising chemopreventive agent againist skin, tongue, oesophaqus and colon carcinogenesis in rodents. Seven new coumarin derivatives structurally related to 7-geranyloxycoumarin were synthesised in good yields by $Cs_2CO_3$/acetonitrile condition. We investigated the effect of anti-inflammatory activity on interleukin-6 for synthesised geranyloxycoumarin derivatives. 6-Geranyoxycoumarin 9 (68.9% / $1{\mu}M$ ; 72.6% / $10{\mu}M$) of the anti-inflammatory activity is far higher than 7-Geranyloxycoumarin 5 (40.1% / $1{\mu}M$ ; 61.1% / $10{\mu}M$) and their other derivatives.

• Biomolecules & Therapeutics
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• v.23 no.5
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• pp.471-478
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• 2015

Colon cancer is considered as the precarious forms of cancer in many developed countries, with few to no symptoms; the tumor is often diagnosed in the later stages of cancer. Monoterpenes are a major part of plant essential oils found largely in fruits, vegetables and herbs. The cellular and molecular activities show therapeutic progression that may reduce the risk of developing cancer by modulating the factors responsible for colon carcinogenesis. Colon cancer was induced with DMH with a dose of (20 mg/Kg/body weight) for 15 weeks by subcutaneous injection once in a week. Myrtenal treatment was started with (230 mg/Kg/body weight) by intragastric administration, one week prior to DMH induction and continued till the experimental period of 30 weeks. The Invivo results exhibit the elevated antioxidant and lipid peroxidation levels in DMH treated animals. The Histopathological analysis of colon tissues well supported the biochemical alterations and inevitably proves the protective role of Myrtenal. Treatment with myrtenal to cancer bearing animals resulted in a remarkable increase in the inherent antioxidants and excellent modulation in the morphological and physiological nature of the colon tissue. It is thus concluded that myrtenal exhibits excellent free radical scavenging activity and anticancer activity through the suppression of colon carcinoma in Wistar albino rats.

• Applied Biological Chemistry
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• v.20 no.1
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• pp.81-87
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• 1977

Resistant and susceptible pine (Pinus thunbergii, Parl) trees to pine gall midge (Thecodiplosis japonensis, Uchida et Inouye) were selected and monoterpene composition in one year old branches, shoots and needles of both groups have been analysed by GLC. The results are summarized as follows; 1. Monoterpene composition in either one year old branches or shoots were not affected by their directions (North or South). 2. Major monoterpenes in one year old branches were ${\alpha}-pinene,\;{\beta}-pinene$, myrcene, limonene, ${\beta}-phellandrene$ and terpinolene. 3. In addition to ${\alpha}-pinene$, camphene, ${\beta}-pinene$, myrcene, ${\Delta}^3-carene$, limonene, ${\beta}-phellandrene$ and terpinolene, several less volatile components which appear to be monoterpenes were also present in shoots and needles. 4. Compared with the susceptible pine, the resistant tree was found richer in limonene composition. 5. ${\beta}-Pinene$ composition in the resistant pine was less than that in the susceptible pine. 6. The difference in the composition of limonene or ${\beta}-pinene$ between two groups of pine trees was discussed in relation to the resistance to pine gall midge.

• KSBB Journal
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• v.28 no.2
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• pp.115-122
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• 2013

Volatile flavor compounds of Chamaecyparis obtuse essential oil were extracted by simultaneous steam distillation extraction (SDE) and supercritical fluid extraction (SFE) and analyzed by GC-MS. A total of 48 and 50 components were identified in essential oil by SDE and SFE, respectively. Monoterpenes, oxygenated monoterpenes, sesquiterpenes, oxygenated sesquiterpenes, and diterpenes in essential oil by SDE were 37.24, 10.9, 9.61, 0.22, and 0.22%, respectively. In the case of SFE, they were 19.1, 23.3, 22.66, 1.31, and 10.57%, respectively. Antioxidant activities were increased with the increase of essential oil up to $80{\mu}L/mL$, irrespective of extraction method. Especially, when the essential oil concentration extracted by SDE was increased from 20 to $80{\mu}L/mL$, the antioxidant activity was increased from 10.5 to 55.1%. However, over $80{\mu}L/mL$ of essential oil, an equilibrium state was maintained. In the case of essential oil extracted by SFE, it was decreased compared to that of SDE. For the improvement of atopic dermatitis, various cosmetics such as an ato-cide soap, ato-cide spray, and ato-cide lotion containing essential oil extracted by SFE were tested. About over 90% was useful for the improvement of atopic dermatitis after 4 weeks of clinical trial targeting 40 female adults. These results demonstrate that ato-cide soap, ato-cide spray, and ato-cide lotion containing essential oil extracted by SFE could be used in functional cosmetics.

• Food Science and Biotechnology
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• v.17 no.3
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• pp.669-674
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• 2008

Zanthoxylum schinifolium and Zanthoxylum piperitum A.P. DC. belong to the Rutaceae family and are perennial, aromatic, and medicinal herbaceous plants. In this study, their aroma compounds were isolated by steam distillation extraction using a Clevenger-type apparatus, and then further analyzed by gas chromatography (GC) and gas chromatograph/mass spectrometry (GC/MS). The yields of the essential oils from Z. schinifolium and Z. piperitum AP. DC. were 2.5 and 2.0%(w/w), respectively, and the color of their oils was quite similar, a pale yellow. From the distilled oil of Z. schinifolium, 60 volatile compounds which make up 87.24% of the total composition were tentatively identified, with monoterpenes predominating. $\beta$-Phellandrene (22.54%), citronellal (16.48%), and geranyl acetate (11.39%) were the predominantly abundant components of Z. schinifolium. In the essential oil of Z. piperitum AP. DC., 60 volatile flavor components constituted 94.78% of the total peak area were tentatively characterized. Limonene (18.04%), geranyl acetate (15.33%), and cryptone (8.52%) were the major volatile flavor compounds of Z. piperitum A.P. DC.

• Journal of Microbiology and Biotechnology
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• v.19 no.10
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• pp.1150-1152
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• 2009

Geraniol (1) is the biogenetic precursor of a number of monoterpenes. We tested various marine-derived microorganisms to determine their ability to biotransform 1. Only Hypocrea sp. was capable of transforming 1 into its oxidized derivative, 1,7-dihydroxy-3,7-dimethyl-(E)-oct-2-ene (2). The structure of the metabolite obtained was assigned on the basis of detailed spectroscopic data analyses.

• Food Science and Biotechnology
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• v.18 no.4
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• pp.833-841
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• 2009

Monoterpenes, in special limonene and its derivatives, are well studied in the literature due to their several properties. They are well recognized as major components of essential oils; some of them, are important industry residues, and others present some important biological activities. In this review, the biotransformation of the inexpensive limonene into flavor compounds was briefly reviewed and the main pathways for limonene biotransformation are presented. Furthermore, some important biological properties of these compounds were also considered, like bactericidal activity, induction of immune response, and role in disease prevention, with a little emphasis on some possibilities related to the mechanisms of anticancer action.

• Natural Product Sciences
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• v.19 no.4
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• pp.355-359
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• 2013

A new monoterpene, crocusatin M (1), was isolated from the flower buds of Buddleja officinalis, together with four known monoterpenes, (6R)-hydroxy-1,1,5-trimethylcyclohex-4-enone (2), (+)-dehydrovomifoliol (3), 7-epiloliolide (4), and crocusatin D (5). Their structures were determined by an extensive analysis of 1D, 2D NMR, HRESI-MS, and CD data as well as by comparison of their spectroscopic data with those of literatures. All isolates were evaluated for inhibitory activities on LPS-induced nitric oxide production in RAW 264.7 cells. Among them, compounds 2 and 3 showed moderate inhibitory effects with $IC_{50}$ values of 63.8 and 24.4 ${\mu}g/ml$, respectively.