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http://dx.doi.org/10.4014/jmb.0904.04013

Microbial Transformation of a Monoterpene, Geraniol, by the Marine-derived Fungus Hypocrea sp.  

Leutou, Alain S. (Department of Chemistry, Pukyong National University)
Yang, Guohua (Department of Chemistry, Pukyong National University)
Nenkep, Viviane N. (Department of Chemistry, Pukyong National University)
Siwe, Xavier N. (Department of Chemistry, Pukyong National University)
Feng, Zhile (Department of Chemistry, Pukyong National University)
Khong, Thang T. (Department of Chemistry, Pukyong National University)
Choi, Hong-Dae (Department of Chemistry, Dongeui University)
Kang, Jung-Sook (College of Dentistry, Pusan National University)
Son, Byeng-Wha (Department of Chemistry, Pukyong National University)
Publication Information
Journal of Microbiology and Biotechnology / v.19, no.10, 2009 , pp. 1150-1152 More about this Journal
Abstract
Geraniol (1) is the biogenetic precursor of a number of monoterpenes. We tested various marine-derived microorganisms to determine their ability to biotransform 1. Only Hypocrea sp. was capable of transforming 1 into its oxidized derivative, 1,7-dihydroxy-3,7-dimethyl-(E)-oct-2-ene (2). The structure of the metabolite obtained was assigned on the basis of detailed spectroscopic data analyses.
Keywords
Biotransformation; geraniol; monoterpene; 1,7-dihydroxy-3,7-dimethyl-(E)-oct-2-ene;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
Times Cited By Web Of Science : 2  (Related Records In Web of Science)
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1 Lee, Y. J., B.-G. Kim, Y. Park, Y. Lim, H.-G. Hur, and J.-H. Ahn. 2006. Biotransformation of flavonoids with Omethyltransferase from Bacillus cereus. J. Microbiol. Biotechnol. 16: 1090-1096   ScienceOn
2 Rasor, J. P. and E. Voss. 2001. Enzyme-catalyzed processes in pharmaceutical industry. Appl. Catal. A Gen. 221: 145-158   DOI   ScienceOn
3 Skouroumounis, G. K. and M. A. Sefton. 2000. Acid-catalyzed hydrolysis of alcohols and their $\beta$-D-glucopyranosides. J. Agric. Food Chem. 48: 2033-2039   DOI   ScienceOn
4 Tang, W. and G. Eisenbrand (Eds.). 1992. Chinese Drugs of Plant Origin, pp. 87-93. Springer-Verlag, Berlin
5 Takabe, K., T. Katagiri, and J. Tanaka. 1975. A new route to 3,7-dimethyl-2,6-octadien-1-ol and 3,7-dimethyl-2-octene-1,7-diol from isoprene. Chem. Lett. 1031-1032
6 Mateo, J. J., N. Gentilini, T. Huerta, M. Jimenez, and R. Di Stefano. 1997. Fractionation of glycoside precursors of aroma in grapes and wine. J. Chromatogr. A 778: 219-224   DOI   PUBMED   ScienceOn
7 Park, M.-K., K.-H. Liu, Y. Lim, Y.-H. Lee, H.-G. Hur, and J.-H. Kim. 2003. Biotransformation of a fungicide ethaboxam by soil fungus Cunninghamella elegans. J. Microbiol. Biotechnol. 13:43-49   ScienceOn
8 Li, X., Y. H. Kim, J. H. Jung, J. S. Kang, D.-K. Kim, H. D. Choi, and B. W. Son. 2007. Microbial transformation of the bioactive sesquiterpene, cyclonerodiol, by the ascomycete Penicillium sp. and the actinomycete Streptomyces sp. Enz. Microbial Technol. 40: 1188-1192   DOI   ScienceOn
9 Kitagawa, I. 1982. Natural products from mevalonic acid pathway, pp. 320-338. In S. Shibata, H. Itokawa, U. Sankawa, J. Shoji, and M. Takido (eds.). Natural Products for Medicinal Use. Nanzando Company, Tokyo
10 Li, X., S. M. Lee, H. D. Choi, J. S. Kang, and B. W. Son. 2003. Microbial transformation of terreusinone, an ultraviolet-A (UVA) protecting dipyrroloquinone, by Streptomyces sp. Chem. Pharm. Bull. 51: 1458-1459   DOI   ScienceOn
11 Li, X., S.-K. Kim, J. H. Jung, J. S. Kang, H. D. Choi, and B. W. Son. 2005. Biological synthesis of polyketides from 6-npentyl-$\alpha$-pyrone by Streptomyces sp. Bull. Korean Chem. Soc. 26: 1889-1890   DOI   ScienceOn
12 Smith, R. V. and J. P. Rosazza. 1975. Microbial models of mammalian metabolism. J. Pharm. Sci. 64: 1737-1759   DOI   PUBMED