• Title/Summary/Keyword: Molecular evolution

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The evolution of radiation-induced point defects near symmetrical tilt Σ5 (310) <001> grain boundary in pure δ-plutonium: A molecular dynamics study

  • Wang, Yangzhong;Liu, Wenbo;Zhang, Jiahui;Yun, Di;Chen, Piheng
    • Nuclear Engineering and Technology
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    • v.53 no.5
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    • pp.1587-1592
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    • 2021
  • The effects of the symmetrical tilt Σ5 (310) <001> grain boundary (GB) on the evolution of radiation-induced point defects in pure δ-plutonium (Pu) were studied by Molecular dynamics (MD) simulations. The evolution of radiation-induced point defects was obtained when primary knock-on atom (PKA) was respectively set as -15 Å and 15 Å far from the GB and the number of residual defects was obtained as the distance from PKA to GB was changed. According to the results, compared with vacancies, interstitial atoms were more easily absorbed by GB. In addition, the formation energy of point defects was also calculated. The results showed that there was almost no difference for the formation energy of vacancies in the all matrix. However, the formation energy of interstitial atoms close to the GB was lower than that in the other bulk regions.

Selection and Directed Evolution of New Microbial Biocatalysts and Their Application to Organic Synthesis

  • Asano, Yasuhisa
    • Journal of Applied Biological Chemistry
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    • v.43 no.4
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    • pp.207-210
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    • 2000
  • As a typical example of the screening for a microbial biocatalyst from nature, isolation of nitrilesynthesizing microorganisms, characterization of a new enzyme aldoxime dehydratase, and its function in the aldoxime-nitrile pathway are introduced. Catalytic properties of some of our enzymes were improved through a direct evolutionary approach.

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AKARI, SCUBA2 AND HERSCHEL DATA OF PRE-STELLAR CORES

  • Ward-Thompson, D.;Pattle, K.;Kirk, J.M.;Andre, P.;Di Francesco, J.
    • Publications of The Korean Astronomical Society
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    • v.32 no.1
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    • pp.117-121
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    • 2017
  • We show Akari data, Herschel data and data from the SCUBA2 camera on JCMT, of molecular clouds. We focus on pre-stellar cores within the clouds. We present Akari data of the L1147-1157 ring in Cepheus and show how the data indicate that the cores are being externally heated. We present SCUBA2 and Herschel data of the Ophiuchus region and show how the environment is also affecting core evolution in this region. We discuss the effects of the magnetic field in the Lupus I region, and how this lends support to a model for the formation and evolution of cores in filamentary molecular clouds.

Core Formation in a Turbulent Molecular Cloud

  • Kim, Jong-Soo
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.2
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    • pp.106.2-106.2
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    • 2011
  • The two competing theories of star formation are based on turbulence and ambipoar diffusion. I will first briefly explain the two theories. There have been analytical (or semi-analytic) models, which estimate star formation rates in a turbulent cloud. Most of them are based on the log-normal density PDF (probability density function) of the turbulent cloud without self-gravity. I will first show that the core (star) formation rate can be increased significantly once self-gravity of a turbulence cloud is taken into account. I will then present the evolution of molecular line profiles of HCO+ and C18O toward a dense core that is forming inside a magnetized turbulent molecular cloud. Features of the profiles can be affected more significantly by coupled velocity and abundance structures in the outer region than those in the inner dense part of the core. During the evolution of the core, the asymmetry of line profiles easily changes from blue to red, and vice versa. Finally, I will introduce a method for incorporating ambipolar diffusion in the strong coupling approximation into a multidimensional magnetohydrodynamic code.

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Evolutionary and Functional Analysis of Korean Native Pig Using Single Nucleotide Polymorphisms

  • Lee, Jongin;Park, Nayoung;Lee, Daehwan;Kim, Jaebum
    • Molecules and Cells
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    • v.43 no.8
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    • pp.728-738
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    • 2020
  • Time and cost-effective production of next-generation sequencing data has enabled the performance of population-scale comparative and evolutionary studies for various species, which are essential for obtaining the comprehensive insight into molecular mechanisms underlying species- or breed-specific traits. In this study, the evolutionary and functional analysis of Korean native pig (KNP) was performed using single nucleotide polymorphism (SNP) data by comparative and population genomic approaches with six different mammalian species and five pig breeds. We examined the evolutionary history of KNP SNPs, and the specific genes of KNP based on the uniqueness of non-synonymous SNPs among the used species and pig breeds. We discovered the evolutionary trajectory of KNP SNPs within the used mammalian species as well as pig breeds. We also found olfaction-associated functions that have been characterized and diversified during evolution, and quantitative trait loci associated with the unique traits of KNP. Our study provides new insight into the evolution of KNP and serves as a good example for a better understanding of domestic animals in terms of evolution and domestication using the combined approaches of comparative and population genomics.

Extensive Reorganization of the Chloroplast Genome of Corydalis platycarpa: A Comparative Analysis of their Organization and Evolution with other Corydalis plastomes

  • Grusamy Raman;SeonJoo Park
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2023.04a
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    • pp.15-15
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    • 2023
  • The chloroplast (cp) is an autonomous plant organelle with an individual genome that codes for essential cellular functions. The architecture and gene content of the cp genome is highly conserved in angiosperms. The plastome of Corydalis belongs to the Papaveraceae family, and the genome is comprised of unusual rearrangements and gene content. Thus far, no extensive comparative studies have been carried out to understand the evolution of Corydalis chloroplast genomes. Therefore, the Corydalis platycarpa cp genome was sequenced, and wide-scale comparative studies were conducted using publicly available twenty Corydalis plastomes. Comparative analyses showed that an extensive genome rearrangement and IR expansion occurred, and these events evolved independently in the Corydalis species. In addition, the protein-coding genes accD and the ndh gene loss events occurred in the common ancestor of the Corydalis and sub-clade of the Corydalis lineage, respectively. The gene ndh lost in the Corydalis-sub clade species is distributed predominantly in the Qinghai-Tibetan plateau (QTP) region. The molecular clock analysis suggests that the divergence time of all the ndh gene lost Corydalis sub-clade species occurred in the 44.31 - 15.71 mya. These results coincide very well with the uplift of the Qinghai-Tibet Plateau in the Oligocene and Miocene periods, and maybe during this period, it probably triggered the radiation of the Corydalis species. To the best of the authors' knowledge, this is the first large-scale comparative study of Corydalis plastomes and their evolution. The present study may provide insights into the plastome architecture and the molecular evolution of Corydalis species.

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The ISM properties under ICM pressure in the cluster environment: NGC4330, NGC4402, NGC4522, NGC4569

  • Lee, Bumhyun;Chung, Aeree
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.1
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    • pp.33.1-33.1
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    • 2013
  • Galaxies undergo various processes in the cluster environment, which could affect their evolution. In particular, ram pressure due to intracluster medium (ICM) can effectively remove HI gas, which is a relatively diffuse form of interstellar medium (ISM). On the other hand, molecular gas is not expected to get easily stripped as atomic gas since it is denser and sitting well within the stellar disk in a deeper potential well. However, cluster galaxies are found to be redder and more passive in star formation activity compared to their field counterpart. This implies that molecular gas may also get affected somehow in dense environments. In this work, we investigate molecular gas properties of a sample of galaxies undergoing HI stripping due to the ICM. We present the 12/13 CO (2-1) data of four spiral galaxies in the Virgo cluster at different ram pressure stripping stages, obtained using the Sub Millimeter Array (SMA). CO morphology of the sample appears to be highly asymmetric and disturbed. Using the ratio of different lines, we probe the molecular gas temperature in different regions. We find higher gas temperature than the range normally found among field galaxies. We discuss how these distinct molecular gas properties may affect star formation and hence the evolution of the cluster galaxy population.

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Deep Impact: Molecular Gas Properties under Strong Ram Pressure Probed by High-Resolution Radio Interferometric Observations

  • Lee, Bumhyun;Chun, Aeree
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.2
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    • pp.39.3-39.3
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    • 2019
  • Ram pressure stripping due to the intracluster medium (ICM) is an important environmental process, which causes star formation quenching by effectively removing cold interstellar gas from galaxies in dense environments. The evidence of diffuse atomic gas stripping has been reported in several HI imaging studies. However, it is still under debate whether molecular gas (i.e., a more direct ingredient for star formation) can be also affected and/or stripped by ram pressure. The goal of this thesis is to understand the impact of ram pressure on the molecular gas content of cluster galaxies and hence star formation activity. To achieve this, we conducted a series of detailed studies on the molecular gas properties of three Virgo spiral galaxies with clear signs of active HI gas stripping (NGC 4330, NGC 4402, and NGC 4522) based on high-resolution CO data obtained from the Submillimeter Array (SMA) and Atacama Large Millimeter/submillimeter Array (ALMA). As a result, we find the evidence that the molecular gas disk also gets affected by ram pressure in similar ways as HI even well inside of the stellar disk. In addition, we detected extraplanar 13CO clumps in one of the sample, which is the first case ever reported in ram pressure stripped galaxies. By analyzing multi-wavelength data (e.g., Hα, UV, HI, and CO), we discuss detailed processes of how ram pressure affects star formation activities and hence evolution of cluster galaxies. We also discuss the origin of extraplanar 13CO, and how ram pressure can potentially contribute to the chemical evolution of the ICM.

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Crystal structure and functional analysis of the surE protein identify a novel phosphatase family

  • Lee, Jae-Young;Kwak, Jae-Eun;Suh, Se-Won
    • Proceedings of the Korean Biophysical Society Conference
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    • 2001.06a
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    • pp.19-19
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    • 2001
  • The genome sequencing has revealed a large number of proteins of unknown or little characterized functions that have been well conserved during evolution. It remains a great challenge to decipher the molecular and physiological functions of these proteins. One example of the evolutionarily conserved protein family with little understood function is the surE family.(omitted)

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