• Design & Manufacturing
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• v.17 no.1
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• pp.20-26
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• 2023

Lab-on-a-disc is a circular disc shape of cartridge that can be used for blood-based liquid biopsy to diagnose an early stage of cancer. Currently, liquid biopsies are regarded as a time-consuming process, and require sophisticated skills to precisely separate cell-free DNA (cfDNA) and circulating tumor cells (CTCs) floating in the bloodstream for accurate diagnosis. However, by applying the lab-on-a-disc to liquid biopsy, the entire process can be operated automatically. To do so, the lab-on-a-disc should be designed to prevent blood leakage during the centrifugation, transport, and dilution of blood inside the lab-on-a-disc in the process of liquid biopsy. In this study, the main components of lab-on-a-disc for liquid biopsy are fabricated by injection molding for mass production, and ultrasonic welding is employed to ensure the bonding strength between the components. To guarantee accurate ultrasonic welding, the flatness of the components is optimized numerically by using the response surface methodology with four main injection molding processing parameters, including the mold & resin temperatures, the injection speed, and the packing pressure. The 27 times finite element analyses using Moldflow® reveal that the injection time and the packing pressure are the critical factors affecting the flatness of the components with an optimal set of values for all four processing parameters. To further improve the flatness of the lab-on-a-disc components for stable mass production, a quarter-disc shape of lab-on-a-disc with a radius of 75 mm is used instead of a full circular shape of the disc, and this significantly decreases the standard deviation of flatness to 30% due to the reduced overall length of the injection molded components by one-half. Moreover, it is also beneficial to use a quarter disc shape to manage the deviation of flatness under 3 sigma limits.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.4
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• pp.50-57
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• 2017

In the injection molding process, a core that builds a space for a product is installed at the internal place in the mold and fabricated as the frame of the mold. In this make up, the fabricating partial form of the mold at a pin is a core pin. The core pin is finer because an injection mold produces miniaturization and integration. On the other hand, when the core is manufactured using the existing centerless grinder, it generates vibrations because of the lack of a fixed zig for a micro size workpiece. For this reason, an existing centerless grinder without a micron size fixed zig, makes a defective product due to vibration and deformation. In this study, a compact grinding system that can be installed using an existing centerless grinder was fabricated to make a micro size core pin. Using the compact grinding system, grinding experiment for core pin was carried out. The performance of the system was confirmed by measuring the surface roughness, roundness, and cylindricity.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1991.11a
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• pp.228-234
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• 1991

오늘날, 플라스틱 사출성형용 금형(Injection Molding)산업은 플라스틱의 수요가 급증함과 아울러 매년 20∼30％의 성장율로 급속히 발전하고 있지만, 이의 생산은 대부분 중소기업에 집중되어 아직도 수동적인 설계 및 생산에서 벗어나지 못하고 있고, 대기업에서는 우리표준에 맞지 않는 값비싼 외국의 “금형설계용 CAD 시스템(Computer Aided Design System)”을 도입하여 금형을 설계, 제작하고있는 설정이다.(중략)

• Proceedings of the KAIS Fall Conference
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• 2002.11a
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• pp.266-268
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• 2002

본 연구에서는 사출 성형품의 품질에 영향을 주는 인자중 금형의 온도에 따라 성형품의 웰드라인의 표면 및 단면의 미시구조에 미치는 영향에 대해 알아보았다. 또한, MmSH process 가 사출성형품에 미치는 영향 또한 알아보았다. 금형온도가 증가함에 따라 유동수지 선단간의 결합이 원활해져 웰드라인의 폭과 길이 모두 저하되는 것을 볼 수 있었으며, MnSH Process는 외관상 일반적인 사출조건에 비해 웰드라인, V-notch가 나타나지 않음을 알 수 있었다.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.05a
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• pp.1225-1226
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• 2010

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1997.10a
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• pp.188-192
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• 1997

A study was conducted to improve validity in new BOM structure through using the similitude of existing BOM in the PDM. The system is developed in Web-Based PDM environments using servlets and database. The system provides the correlation information between parts to inflect the reusability of existing BOM. User-defined correlation is used to inform the relations between design precedence and co-relations of parameters. Realistic application in injection mold production is constructed using this structure.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2009.06a
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• pp.9-10
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• 2009

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.5 no.2
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• pp.59-62
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• 1999

After reported that Styrene dimer and Styrene trimer was Endocrine Disrupter, if it was a fact or not, the sales of PSP noodle cup was rapidly decreased and social responsibilities of the substitution materials development was raised. Therefore we had studied many materials like paper, pulp mold, PP injection molding, PP lamination, etc as substitution materials and selected paper cup which was safe in many sides and easy to recycle. Mainly we had checked the shape, safety, stability and recycling possibility of paper cup and secured many data which could prove them.

• Proceedings of the KAIS Fall Conference
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• 2001.05a
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• pp.257-260
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• 2001

본 논문은 사출금형설계 관련 지식과 경험을 전산정보화 하고 유동해석프로그램과 기계적 성능예측 프로그램을 결합시켜 전문가시스템을 구축하였다. 전문가시스템은 주어진 설계에 대해 유동해석프로그램을 구동시켜 열기계적 데이터베이스를 얻고, 필요에 따라 기계적 성능예측 프로그램을 수행시켜 설계의 최종적인 진단을 수행하게 된다. 이러한 과정으로 설계에 대한 평가를 수행하며, 만일 설계가 잘못된 것으로 판정이 되면 그에 해당하는 대안을 제시토록 하여 합리적인 설계가 가능하도록 하였다.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2015.05a
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• pp.94-94
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• 2015

사출금형의 표면은 제작되는 제품의 표면에 노출되기 때문에 표면조도 및 품질이 제품의 품질을 결정하는 데에 매우 중요하게 작용한다. 본 연구에서는 대면적 전자빔을 이용한 사출금형의 표면개질을 수행하였다. 대면적 전자빔 표면처리를 통하여 사출금형의 표면조도를 크게 줄일 수 있었으며, 표면 경도를 증가시켜 금형의 수명을 크게 향상시킬 수 있을 것으로 기대되었다.