• Journal of the Institute of Electronics Engineers of Korea SC
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• v.44 no.3
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• pp.45-50
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• 2007

We present a auto compensating quantum key distribution system based on optical fiber at 1550nm. In the quantum key transmission system, main control board and phase modulation driving board are fabricated for auto controlling quantum key distribution(QKD). We tested the single photon counts per dark counts for a single photon detector, quantum key distribution rate($R_{sift}$) and the quantum bit error rate (QBER). Quantum bit error rate of 3.5% in 25km QKD is obtained. This system is commercially available.

• The Journal of the Korean bone and joint tumor society
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• v.3 no.2
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• pp.69-79
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• 1997

Objective : The objective of this study was to compare expression of various proto-oncogenes and rates of apoptosis in osteosarcoma patients. Modulation of apoptosis may influence resistance to chemotherapy and therefore affect the outcome of cancer treatment. Osteosarcoma is one of the most fatal malignancies in young adolescents and investigation of the role of apoptotic cell death is warranted in relation to chemotherapy and tumor outcome. Design : The terminal deoxynucleotidyl transferase to exposed 3'-hydroxyl termini of DNA (TUNEL method) staining method has been applied for the in situ detection of DNA double strand breaks. Patients : Thirty-three osteosarcomas in various stages of differentiation from twenty-nine patients were investigated immunohistochemically for p53, Bcl-2 and TUNEL method for apoptosis. Results and conclusion; We have found that higher level of wild type p53 were correlated with enhanced expression of apoptosis. Increased apoptosis rates were found in cases of negative Bcl-2 expression. In the present study, we have concluded that a significant proportion of osteosarcoma, a tumor in which resistance to chemotherapy often occurs, express high levels of p53 and low levels of Bcl-2. Our data provide further evidence for cross-talk between Bcl-2 and p53 and suggests that these genes are important determinants of drug-induced apoptosis.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.43 no.12 s.354
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• pp.9-15
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• 2006

In this paper, signal processing techniques for noncoherent impulse-radio-based UWB (IR-UWB) communication system are proposed to provide system implementation of low power consumption and low complexity. The proposed system adopts a simple modulation technique of OOK (on-oft-keying) and noncoherent signal detection based on signal amplitude. In particular, a technique of a novel high speed digital sampler using a stable, lower reference clock is developed to detect nano-second pulses and recover digital signals from the pulses. Also, a 32 bits Turyn code for data frame synchronization and a convolution code as FEC are applied, respectively. To verify the proposed signal processing techniques for low power, low complexity noncoherent IR-UWB system, the proposed signal processing technique is implemented in FPGA and then a short-range communication system for wireless transmission of high quality MP3 data is designed and tested.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.37 no.3
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• pp.9-17
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• 2000

In this paper we implement computer simulation system of 4FSK signal MODEM using Quadrature detector and analyze overall tranceiver system. We follow the FLEX wireless paging system standards and construct premodulation filter and data frame. We propose an efficient open loop symbol timing recovery algorithm which takes advantage of 128 bit length preamble pattern and also propose a 32 bit UW pattern which Is based on the optimal UW detection method, and excellent aperiodic autocorrelation characteristic. The BER simulation in the fading channel as well as AWGN is performed with BCH coding and Interleaving to the Quadrature detector system and it is shown that a high coding fain occurs in the fading channel rather than AWGN channel.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.10 s.89
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• pp.952-960
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• 2004

PSK(Phase Shift Keying) is useful because of the power and spectral efficient modulation. In this paper, no additional hardware will be needed to support various transmit mode in the suggested DSP scheme. We design and implement the synchronization algorithm for M-ary PSK(M=2, 4) demodulator based on DSP scheme, instead of complex analog PSK demodulator. TMS320C6203 is used as DSP. We check the all kinds of waveforms via the graph view window after software programming the emulation on the DSP tool. The result of implementation proves that demodulator using the suggested algorithm has equal performance with demodulator using analog circuits.

• Journal of the Korean Ceramic Society
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• v.40 no.11
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• pp.1073-1077
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• 2003

The Sn $O_2$-based gas sensors can detect inflammable and toxic gases of low concentration by the modulation of surface resistance, but they lack in selectivity on the whole. To give selectivity to the Sn $O_2$-based gas sensors, studies on the sensing mechanism, selective gas sensing materials and signal processing techniques are demanded. Ethanol (C$_2$ $H_{5}$OH) and acetonitrile ($CH_3$CN) were confirmed to undergo catalytic oxidation on Sn $O_2$ by gas chromatography. PdCl$_2$-doped Sn $O_2$ showed excellent sensitivity to ethanol and acetonitrile, while La$_2$ $O_3$-doped Sn $O_2$ showed excellent sensitivity to ethanol, but poor sensitivity to acetonitrile. Using these two sensors and pattern recognition, the selectivity to acetonitrile is greatly enhanced. The minimum detection level of acetonitrile was 15 ppm in air and 20 to 100 ppm when exposed to interfering gases together with acetonitrile.

• IMMUNE NETWORK
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• v.11 no.6
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• pp.383-389
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• 2011

Background: EY-6 is one of the newly synthesized indoledione derivatives to induce tumor cell-specific cell death. In this study, we investigated the mechanism of immunological death induced by EY-6 at mouse colon cancer cell as well as at the normal immune cell represented by dendritic cell. Methods: C57BL/6 mouse syngeneic colon cancer cell MC38 was treated with EY-6, and analyzed by MTT for viability test, flow cytometry for confirming surface expressing molecules and ELISA for detection of cytokine secretion. Normal myeloid-dendritic cell (DC) was ex vivo cultured from bone marrow hematopoietic stem cells of C57BL/6 mice with GM-CSF and IL-4 to analyze the DC uptake of dead tumor cells and to observe the effect of EY-6 on the normal DC. Results: EY-6 killed the MC38 tumor cells in a dose dependent manner (25, 50 and $100{\mu}M$) with carleticulin induction. And EY-6 induced the secretion of IFN-${\gamma}$ but not of TNF-${\alpha}$ from the MC38 tumor cells. EY-6 did not kill the ex-vivo cultured DCs at the dose killing tumor cells and did slightly but not significantly induced the DC maturation. The OVA-specific cross-presentation ability of DC was not induced by chemical treatment (both MHC II and MHC I-restricted antigen presentation). Conclusion: Data indicate that the EY-6 induced tumor cell specific and immunological cell death by modulation of tumor cell phenotype and cytokine secretion favoring induction of specific immunity eliminating tumor cells.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.11
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• pp.7582-7588
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• 2015

Noncoherent receivers are favored for block-code-modulated ultrawideband impulse radio (UWB-IR) systems because of their low implementation complexity compared with coherent rake receivers. However, existing noncoherent schemes, such as transmitted reference (TR) systems and averaged differential receivers (ADR), suffer from performance degradation and energy efficiency loss. Codeword matching and signal aggregation (CMSA) is a low complexity noncoherent receiver for UWB-IR. As the frame/symbol duration is shortened to boost data rate, interframe interference (IFI) or intersymbol interference (ISI) occurs and degrades the detection performance of CMSA. In this paper, block coded correlator which consists of the delay components and the reference signal is proposed to improve the performance of the receiver. Simulation results show that the proposed system leads to the better performance compared to the conventional CMSA receiver.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.13 no.10
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• pp.2197-2204
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• 2009

In this paper, we analyze the performance of the sphere decoding algorithm at MIMO system. The BER performance of this algorithm is the same as that of ML receiver, but computational complexity of SD algorithm is much less than that of ML receiver. The independent signals from each transmit antennas are modulated by using the QPSK and 16QAM modulation in the richly scattered Rayleigh flat-fading channel. The received signals from each receivers is independently detected by the receiver using Fincke & Pohst SD algorithm, and the BER output of the algorithm is compared with those of ZF, MMSE, SIC, and ML receivers. We also investigate the Viterbo & Boutros SD algorithm which is the modified SD algorithm, and the BER performance and the floting point operations of the algorithms are comparatively studied.

• Journal of Nutrition and Health
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• v.53 no.6
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• pp.563-569
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• 2020

Purpose: The vascular smooth muscle cells (VSMCs) in mature animals have implicated to play a major role in the progression of cardiovascular diseases such as atherosclerosis. This study aimed at optimizing the protocol in culturing primary VSMCs (pVSMCs) from rat thoracic aorta and investigating the effect of cellular zinc (Zn) deficiency on cell proliferation of the isolated pVSMCs. Methods: The thoracic aorta from 7-month-old Sprague Dawley rats was isolated, minced and digested by the enzymatic process of collagenase I and elastase, and then inoculated with the culture Dulbecco Modified Eagle Medium (DMEM) at 37℃ in an incubator. The primary cell culture morphology was observed using phase-contrast microscopy and cellular Zn was depleted using Chelex-100 resin (extracellular zinc depletion only) or 3 µM N,N,N',N'-tetrakis(2-pyridinylmethyl)-1,2-ethanediamine (TPEN) (extracellular and intracellular zinc depletion). Western blot analysis was used for the detection of SM22α and calponin as smooth muscle cell marker proteins and von Willebrand factor as endothelial cell marker protein to detect the culture purity. Cell proliferation by Zn depletion (1 day) was measured by MTT assay. Results: A primary culture protocol for pVSMCs from rat thoracic aorta was developed and optimized. Isolated cultures exhibited hill and valley morphology as the major characteristics of pVSMCs and expressed the smooth muscle cell protein markers, SM22α and calponin, while the endothelial marker von Willebrand factor was hardly detected. Zn deprivation for 1 day culture decreased rat primary vascular smooth muscle cell proliferation and this pattern was more prominent under severe Zn depletion (3 µM TPEN), while less prominent under mild Zn depletion (Chelexing). Conclusion: Our results suggest that cellular Zn deprivation decreased pVSMC proliferation and this may be involved in phenotypic modulation of pVSMC in the aorta.