• 한국콘텐츠학회논문지
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• 제15권10호
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• pp.616-625
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• 2015

최근 한의학에 대한 과학적 접근이 진행되면서 한약재 성분의 효능을 검증하고자 하는 다양한 분자 생물학 분야의 연구가 진행되고 있다. 하지만 관련 한약재의 주요 성분과 관련된 생화학적 기작을 손쉽게 검색할 수 있는 시스템이 갖추어져 있지 못한 실정이다. 본 연구는 국내 한약재에 대한 약효 성분과 생물학적 기작에 대한 정보를 수집 및 텍스트마이닝을 수행하여 한약재 정보 데이터베이스를 구축하고자 하였다. 연구자가 손쉽게 분석된 한약재의 화합물, 유전자 그리고 생물학적 상호작용 정보를 검색할 수 있는 웹사이트 원형을 개발하였다. 문헌 분석결과 한의학분야 주요 화합물 및 유전자/단백질 정보를 추출할 수 있었고 현대 한의학 연구 현황의 특징을 보여주었다. 분석된 결과는 웹을 통해 한약재별 PubMed 문헌 정보와 관련된 한약재의 약재 정보 및 생물학적 상호작용 정보를 가시화하여 볼 수 있도록 개발하였다.

• 한국의사학회지
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• 제24권2호
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• pp.69-76
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• 2011

This study focuses on the origin and the literature of eyelid-acupuncture, nunchim therapy in Korea and its present clinical usage in modern Korea. The therapy is called nunchim at local area of Korea and has been transmitted as folk remedy because its real practice has been fallen into oblivion in the regular medical institution in modern Korea. On the contrast, some old women called nunchim-halmae, still know its practice and give medical therapy in a certain irregular way. While many kinds of eye clinics are prevalent in Korea, some patients with chronic eye diseases still go to get the nunchim therapy from nunchim-halmae. Moreover some oriental medical doctors have learned the therapy from nunchim-halmae and performed that medical service in their clinics in spite of absence of medical insurance coverage. Nunchim has unique historic origin and transmission linage in Korea, which was shed light on by this research. We present concise structure of the essence of nunchim therapy and 80 year old woman case of dramatic eye curing with the therapy.

• 동의생리병리학회지
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• 제32권1호
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• pp.1-12
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• 2018

This article is for understanding characteristics of febrile disease through analysing usage of representative prescriptions in "Wenbingtiaobian", composition of their related prescriptions and their coverage of modern diseases. Analysis of prescriptions was based on "Translation of Wenbingtiaobian", "Modern Shanhanlun" and "Herbal Formula Science" and clinical papers were searched in China Academic Journals(CAJ) of China National Knowledge Infrastructure(CNKI). Conclusions are as follows. First, principles of modifying or formulating prescriptions for febrile diseases are clearing heat, nourishing yin or dispelling dampness. Second, Zengyechengqitang, Xinjiahuanglongtang and Huweichengqitang are applied to pattern of bowel excess such as constipation or ileus. Third, Jiajianfumaitang is applied to heart diseases, Sanjiafumaitang to liver and heart, Dadingfengzhu to liver diseases. Fourth, Jiajianzhengqisan related prescriptions are applied to spleen diseases like conspitation, diarrhea or gastritis. Fifth, Baihujiarenshentang is applied to diabetes or fever and Baihujiaguizhitang to gout or arthritis. Sixth, Xuanbaichengqitang is applied to lung diseases and Taorenchengqitang to gynecology diseases. Seventh, Sanrentang is applied lung diseases like cough or pneumonia, spleen diseases like diarrhea or enteritis and kidney diseases like edema, arthritis or leucorrhea. Eighth, Yinqiaosan and Sangjuyin tend to be applied to exogenous diseases and diseases of five organs of sense, Jiajianfumaitang and Sanjiafumaitang to heart diseases, Angongniuhuangwan to encephalopathy, Qingyingtang and Huabantang to skin diseases, Zengyetang to gastrointestinal disorders, Shashenmaidongtang to lung or spleen diseases.

• 한국의사학회지
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• 제28권1호
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• pp.111-119
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• 2015

Objectives : The Dongui Bogam in My Hand', which is an output of computerizing Donguibogam (Principles and Practice of Eastern Medicine), is an interim outcome of the research project led by the Korea Institute of Oriental Medicine. This study examined the process in which Donguibogam, a record in Chinese and a classic of Oriental medicine, expanded into a modern content. Methods : This study will classify the modernization of Donguibogam into three 'contents' that form Donguibogam, 'container' that will hold the contents, and 'community' that is the consumer of Donguibogam. Towards the end, this study will sketch out the status of computerizing Chinese records in Korea, and point out the reality faced by computerization of ancient documents on Oriental medicine as well as the direction for the future. Results : 'The Dongui Bogam in My Hand' has been downloaded more than 10,000 times for 4 months since it releases in August 2014, and is used for at least 6,000 times on average every month. This achievement can be due to the two following reasons. First, the application contains high-quality contents such as the original text of Donguibogam as well as Korean and English translations. Second, it satisfied the needs of Donguibogam users with (1) the Browse function that well displays the table of contents, (2) the Search function that separates the title from the main text, and (3) the Personalization function designed to link and share relevant knowledge. Conclusions : Computerization of Chinese records was triggered by the request of the academia, but it was accelerated after being selected as a public laboring project to overcome the IMF crisis. However, computerization of ancient documents is not a simple task but a field of study to modernize classical knowledge. The success or failure of computerization of Chinese records is determined by whether high-quality modern 'contents' are secured, whether the 'container' design adequately implements the search, browse and link functions, and how well it fulfills the needs of the consumer 'community'.

• 대한본초학회지
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• 제35권2호
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• pp.15-29
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• 2020

Objectives : This study aimed to review the change in the origin of Sokdan(續斷) by diachronically analyzing literature data from Korea and China. Methods : Literature records describing the origin(synonyms, location of production, description) of Sokdan were collected, records were divided into periods. The main contents were included in the results, and original texts were edited and summarized in the table. Results : Sokdan, whose leaves resemble Jeoma(苧麻)(SJ), was first recorded in 《Xinxiubencao(新修本草)》, and described in detail in 《Bencaotujing(本草圖經)》 during the Tang and Song dynasties in China. In modern times, SJ was assumed to be genus Phlomoides or Lamium; however, records of the plant have decreased. Finally, SJ was not included in the 《Pharmacopoeia of the People's Republic of China》 as Sokdan. However, 《Diannanbencao(滇南本草)》, 《Diannanbencaotushuo(滇南本草圖說)》, 《Zhiwumingshitukao(植物名實圖考)》 described Sokdan of dian(滇). It was assumed genus Dipsacus. From the 1950s onwards, Sokdan is described in the literature as a member of the genus Dipsacus. In korea, SJ was recorded in 《Hyangyakjipseongbang(鄕藥集成方)》 and 《Dongeuibogam(東醫寶鑑)》 during the Joseon dynasty. In modern times, the genera Phlomoides and Lamium were mostly recorded as the origin of Sokdan. Conclusions : Several species have been described as Sokdan over the years in China, but since the 1950s, the genus Dipsacus was noted as the origin of Sokdan. In Korea, SJ was used in the past, thus Sokdan was recorded as P. umbrosa in 《The Korean Herbal Pharmacopoeia(KHP)·1985》. However, 《KHP·1998》 referred to P. umbrosa as Hansokdan and D. asperoides as Sokdan.

• Environmental Analysis Health and Toxicology
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• 제31권
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• pp.8.1-8.2
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• 2016

A simple linear model to test the hypothesis based on one-on-one relationship has been used to find the causative factors of diseases. However, we now know that not just one, but many factors from different systems such as chemical exposure, genes, epigenetic changes, and proteins are involved in the pathogenesis of chronic diseases such as diabetes mellitus. So, with availability of modern technologies to understand the intricate nature of relations among complex systems, we need to move forward to the future by taking complex systems model.

• 수면정신생리
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• 제10권1호
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• pp.12-19
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• 2003

Sleepiness, or hypersomnia, is a relatively common complaint and one of the main problems of modern society. Accurate evaluation and diagnosis of sleepiness are important. The methods used for evaluating sleepiness are subjective measures or self-evaluations, performance decrease measures, sleep propensity measures, and arousal decrease measures. A clear and detailed history is important in differential diagnosis of sleepiness because symptoms of sleepiness may be expressed in terms of 'tiredness' or 'fatigue' that do not directly denote sleepiness. Comprehensive diagnostic evaluation is also invaluable because these symptoms may result from a variety of causes ranging from medical disorders to insufficient nocturnal sleep.

• Archives of Plastic Surgery
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• 제39권4호
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• pp.281-283
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• 2012

The mandibular condyle is a region that plays a key role in the opening and closing of the mouth, and because fracture causes functional and aesthetic problems such as facial asymmetry, it is very important to perform accurate reduction. Traditionally, there has been disagreement on how to manage fracture of the mandibular condyle. This review explores the misunderstanding of mandibular condyle fracture treatment and modern-day treatment strategies.

• Journal of Yeungnam Medical Science
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• 제41권1호
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• pp.4-12
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• 2024

Biomaterials have been used to supplement and restore function and structure by replacing or restoring parts of damaged tissues and organs. In ancient times, the medical use of biomaterials was limited owing to infection during surgery and poor surgical techniques. However, in modern times, the medical applications of biomaterials are diversifying owing to great developments in material science and medical technology. In this paper, we introduce biomaterials, focusing on calcium phosphate ceramics, including octacalcium phosphate, which has recently attracted attention as a bone graft material.

• 정신신체의학
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• 제30권2호
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• pp.99-111
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• 2022

번식은 진화의 핵심 요인이면서, 동시에 의학의 중요한 관심사다. 특히 생물학적 적합도 최대화에 반하는 현대 산업 사회의 낮은 출산율에 대해 진화학자들이 다양한 이론과 가설을 제안했다. 출산은 번식 적합도에 미치는 가장 중요한 요인이기 때문에 출산 행동 및 의도와 관련된 다양한 심리적 모듈이 진화했을 것으로 추정된다. 성적 욕구, 사회적 지위 욕구, 양육 욕구, 출산 욕구(또는 아기 갈망)등이 번식과 관련된 진화 심리적 모듈로 제안되었다. 과거 진화적 적응 환경과 현대 산업 사회 환경의 불일치로 인해 과거에는 적응적이었던 심리적 모듈이 지금은 부적응적으로 발현될 수도 있다. 현대 사회에서 출산 의사에 영향을 미치는 진화생태학적 요인은 크게 개인의 성격적 요인, 유년기 생애사적 경험, 가임기 사회생태적 경험이 있다. 본 연구는 출산 의사 결정에 영향을 미치는 진화정신의학적 요인에 관한 가설과 모델을 고찰하고, 현대 산업 사회의 저출산 현상과 관련된 심리적 요인을 진화의학적 관점에서, 정신적, 사회적, 생태적 요인을 중심으로 개괄한다.