Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
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Time to change from a simple linear model to a complex systems model

  • Hong, Yun-Chul (Institute of Environmental Medicine, Seoul National University College of Medicine)
  • Received : 2016.04.15
  • Accepted : 2016.04.20
  • Published : 2016.01.01
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Abstract

A simple linear model to test the hypothesis based on one-on-one relationship has been used to find the causative factors of diseases. However, we now know that not just one, but many factors from different systems such as chemical exposure, genes, epigenetic changes, and proteins are involved in the pathogenesis of chronic diseases such as diabetes mellitus. So, with availability of modern technologies to understand the intricate nature of relations among complex systems, we need to move forward to the future by taking complex systems model.

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References

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  2. Northrop RB. Introduction to complexity and complex systems. Boca Raton: CRC Press; 2010, p.1-21.