• Journal of Korean Neurosurgical Society
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• 제45권5호
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• pp.300-302
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• 2009

The authors present a rare case of severe vasospasm following the rupture of arteriovenous fistula. On initial CT scan, hematoma in the corpus callosum and left inferior frontal region with surrounding cerebromalacia and all ventricles without apparent subarachnoid hemorrhage were seen. Angiograms showed arterivenous fistula but did not show cerebral vasospasm. Thirteen days after admission the neurological state of patient suddenly deteriorated and bilateral motor weaknesses developed. Following angiograms revealed severe narrowing on the supraclinoid portion of bilateral internal carotid arteries, bilateral anterior cerebral arteries and bilateral middle cerebral arteries. Transluminal angioplasty and intra-arterial papaverine infusion were performed. The patient remained stable with moderate neurologic deficits.

• Biomolecules & Therapeutics
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• 제16권4호
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• pp.416-424
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• 2008

A series of N,N'-substituted iminodiacetamide derivatives was synthesized and evaluated their inhibitory effects on the histamine-induced smooth muscle contraction in guinea-pig ileum and on the histamine release from IgE-sensitized RBL-2H3 cells (rat basophilic leukemia cell line). Compounds A3, A4 and A5 which have 1-(4-chlorobenzhydryl) piperazine moiety, showed both moderate antihistamine activity and histamine release inhibitory activity.

• Earthquakes and Structures
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• 제26권4호
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• pp.269-283
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• 2024

When a reinforced concrete (RC) structure is exposed to a corrosive environment for an extended period of time, the material qualities deteriorate, resulting in a loss in seismic performance. Engineered Cementitious Composites (ECC) have been used to reinforce the corroded RC structure, which can achieve reinforcement effectiveness for a small change in cross-section size. In this work, finite element models of unjacketed RC pier and ECC jacketed pier were established and verified by experimental tests, with the buckling effect of longitudinal reinforcement considered. Compared with the unjacketed pier, the displacement of the pier top of the ECC jacketed pier was reduced by about 9.52% under earthquake action. In the case of moderate and major earthquakes, the probability of exceedance of ECC jacketed pier is significantly reduced. For the case of rare earthquake loading, with the ECC jacket, the e of the pier experiencing serious damage and complete damage states is reduced by 10.29% and 29.78%, respectively.

• The Journal of Korean Physical Therapy
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• 제28권5호
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• pp.328-333
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• 2016

Purpose: This study was to investigate the correlation between pain, disability and quality of life among adolescents and office workers with neck and shoulder pain. Methods: Twenty-four subjects (mean age=24.92 years, SD=3.94, range=20-37) with neck and shoulder pain participated in this study. The outcome measures of the study were visual analogue scale (VAS), neck disability index (NDI), shoulder pain and disability index (SPADI), short form-36 (SF-36) for neck and shoulder pain and disability, quality of life. Pearson's correlation and Speaman's rank correlation were used to measure the association between VAS and NDI, SPADI, SF-36. Results: The VAS showed a positive correlation between weak to moderate with the NDI and SPADI, but no significantly correlated (${\rho}=0.34$, ${\rho}=0.25$). The moderate positive correlation and significant correlation were observed between NDI and SPADI (${\rho}=0.43$, p<0.05). The PCS of SF-36 was significantly negative correlated with the VAS (${\rho}=-0.24$), NDI and SPADI (${\rho}=-0.63$, ${\rho}=-0.59$, p<0.05). Conclusion: The pain and disability of neck and shoulder has closely relevance. And, the pain and disability of neck and shoulder has a negative impact on the quality of life.

• 디지털융복합연구
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• 제16권4호
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• pp.69-77
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• 2018

최근 조직은 팀을 중심으로 하는 기업 구조의 변화를 겪고 있다. 따라서 본 연구에서는 팀 리더십의 중심인 공유리더십과 구성원의 혁신행동과의 관계를 살펴보고, 이들의 관계에서 신뢰가 어떠한 조절 역할을 수행하는지를 파악하고자 한다. 이를 위해, 문헌조사를 통해 공유리더십이 혁신행동에 영향을 미칠 것 이라는 연구모형 및 가설을 설정하였다. 또한, 이들의 관계에서 신뢰의 조절효과를 파악하였다. 실증분석을 위해, 대구 경북 지역의 대기업에 종사하는 조직 구성원을 대상으로 설문조사를 진행하였고, 다중회귀분석 및 계층적 회귀분석을 실시하여 가설검증을 실시하였다. 분석결과, 공유리더십은 혁신행동에 유의미한 영향을 미치는 것으로 나타났다. 특히, 구성원간의 신뢰는 공유리더십과 혁신행동의 관계를 조절하는 것으로 나타났다. 이러한 연구 결과는 인적자원의 중요성이 증대되는 현 시점에서의 기업 조직의 주요한 전략적 인적자원활용 방안으로 활용 될 것이다.

• 대한간호학회지
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• 제41권2호
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• pp.256-268
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• 2011

Purpose: The purpose of this study was to use meta-analysis to examine recent domestic articles related to attention deficit hyperactivity disorder (ADHD) in school-age children. Methods: After reviewing 213 articles published between 1990 and 2009 from and cited in RISS, KISS, and DBpia, the researchers identified 24 studies with 440 research variables that had appropriate data for methodological study. SPSS 17.0 program was used. The outcome variables were divided into five types: Inattention, hyperactive impulsive, intrinsic, extrinsic, and academic ability variables. Results: Effects size of overall core symptoms was 0.47 which is moderate level in terms of Cohen criteria and effects size of overall negative variables related ADHD was 0.27 which is small level. The most dominant variable related to ADHD was obtained from hyperactive-impulsive (0.70). Also academic ability (0.45), inattention (0.37), and intrinsic variables (0.29) had a small effect whereas extrinsic variables (0.13) had little effect on descriptive ADHD study. Conclusion: The results reveal that ADHD core symptoms have moderate effect size and peripheral negative variables related ADHD have small effect size. To improve the reliability of the meta-analysis results by minimizing publication bias, more intervention studies using appropriate study designs should be done.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7843-7846
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• 2015

Background: Some matrix metalloproteinases (MMPs) are involved in invasion and metastasis of head and neck squamous cell carcinoma (HNSCC). However, there are few studies on association between stromelysin-2 (ST-2) and invasive behavior of HNSCC. The purpose of this study was to investigate Stromelysin-2 expression by immunohistochemistry. Materials and Methods: This study was conducted on 81 specimens, including 61 HNSCC and 20 non neoplastic epithelium. Sections with 5 micron thickness were prepared and stained with immunohistochemistry technique. Then expression of ST-2 was evaluated according to percentage of stained cells and intensity of staining. Data were analyzed by SPSS (V.21) using Kruskal-Wallis and Tukey tests (P<0.05). Results: The 61 HNSCC specimens were grades I 36.1%, II 34.4% and III 29.5%. The level of ST-2 expressions were moderate (++) and intensive (+++) in 21.3% and 78.7% of tumors, respectively. The ST-2 expression level was only significant between the tumors with grade I and grade III (P=0.016). Tumors presented ST-2 expression with staining intensity of mild 6.6%, moderate 26.2% and strong 67.2%. Staining intensity of ST-2 in grade I tumors was significantly lower than grade II and grade III (P<0.05), and there was no significant difference between grades II and III (P=0.99). Conclusions: According to this study, the expression of ST-2 is associated with histopathological grade and tumor differentiation in HNSCCs.

• 보건교육건강증진학회지
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• 제33권1호
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• pp.49-60
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• 2016

Objectives: This study aims to assess the relationships between individual, social and physical environmental correlates and physical activity (PA) and sedentary behavior (SB) in Korean children. Methods: A total of 1,134 elementary school students (512 boys, $5^{th}$ and $6^{th}$ graders) in Seoul participated in the survey including self-reported moderate and vigorous intensity PA and SB as well as demographic and psychological correlates. These data were matched them with school- and community-level environmental data from the government sources. The relationships of the multilevel correlates with PA and SE were analyzed using gender-specific hierarchical regression analysis. Results: Boys were more active than girls, but there was no gender difference in SB. Students with higher levels of self-efficacy were more likely to participate in moderate and vigorous PA. There were gender-specific associations between social and physical environments correlates and PA. Boys with higher levels of self-esteem and self-efficacy were less likely to involve in SB. Girls in the $6^{th}$ grade were more likely to involve in SB. Conclusions: In order to encourage PA and discourage SB in children, school- and community-level environmental support should be considered along with programs to improve self-efficacy and self-esteem.

• Clinical and Experimental Pediatrics
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• 제59권9호
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• pp.362-367
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• 2016

Purpose: This study aimed to investigate the clinical significance of serum alanine aminotransferase (ALT) levels in children with nonalcoholic fatty liver disease (NAFLD) and the effect of lifestyle intervention on NAFLD. Methods: The clinical data of 86 children diagnosed with NAFLD were reviewed retrospectively. Forty-six patients belonged to the elevated ALT group and 40 to the normal ALT group. The clinical parameters of patients with NAFLD were also compared based on the status of ALT levels after lifestyle intervention. Results: Patients with elevated ALT had significantly higher body mass index (BMI) scores than those with normal ALT (P<0.05). Of all the patients with elevated ALT, 89% exhibited moderate or severe degree of fatty change in the liver on ultrasonographic examination, whereas most patients with normal ALT exhibited mild or moderate degree changes. Liver biopsy was performed in 15 children with elevated ALT and all showed mild histological changes. Of all patients with elevated ALT, 49% achieved normal ALT levels after lifestyle intervention. Those with more severe histological changes tended to have continuously increasing ALT levels. There was no correlation between the normalization of posttreatment ALT level and BMI, as well as ultrasonographic findings at diagnosis. Conclusion: ALT elevation in NAFLD is highly associated with higher BMI scores and more severe degree of fatty changes on ultrasonographic examination. Lifestyle intervention can significantly improve ALT in children with NAFLD. The degree of histologic changes appears to be a predictor of the treatment response to NAFLD.

• Journal of Dental Anesthesia and Pain Medicine
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• 제18권1호
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• pp.27-33
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• 2018

Background: Temporomandibular disorder (TMD) represents a subgroup of painful orofacial disorders involving pain in the temporomandibular joint (TMJ) region, fatigue of the cranio-cervico-facial muscles (especially masticatory muscles), limitation of mandible movement, and the presence of a clicking sound in the TMJ. TMD is associated with multiple factors and systemic diseases. This study aimed to assess the prevalence of TMD in Nepalese subjects for the first time. Methods: A total of 500 medical and dental students (127 men and 373 women) participated in this study from May 2016 to September 2016. The Fonseca questionnaire was used as a tool to evaluate the prevalence of TMD, and Fonseca's Anamnestic Index (FAI) was used to classify the severity of TMD. Results: The majority of the participants with TMD had a history of head trauma, psychological stress, and dental treatment or dental problems. The prevalence of TMD in Nepalese students was mild to moderate. Conclusions: The prevalence of TMD in Nepalese subjects was mild to moderate. The majority of the study subjects had eyesight problems, history of head trauma, psychological stress, and drinking alcohol and had received dental treatments.