• Title/Summary/Keyword: Model based

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Effects of Positive Psychological Capital, Job Crafting and Nursing Work Environment on Job Satisfaction of Clinical Nurses (임상간호사의 긍정심리자본, 잡 크래프팅과 간호근무환경이 직무만족에 미치는 영향)

  • Kyung Ae Park;Ja-Sook Kim
    • Journal of Industrial Convergence
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    • v.22 no.3
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    • pp.67-78
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    • 2024
  • The purpose of this study is to identify the factors affecting job satisfaction by examining the positive psychological capital, job crafting, and nursing work environment of clinical nurses, and to provide foundational data necessary to devise strategies for enhancing job satisfaction. Data were collected online from 208 clinical nurses working in three comprehensive hospitals located in J city from March 15 to March 30, 2023. Data were analyzed using the SPSS/WIN 26.0 program. The influencing factors on subjects' job satisfaction were marital status, education level, salary satisfaction, workload, clinical experience, positive psychological capital, job crafting, and nursing work environment. A hierarchical regression analysis following the order of general characteristics, positive psychological capital, nursing work environment, and job crafting identified nursing work environment (𝛽=.37, p<.001), job crafting (𝛽=.35, p<.001), positive psychological capital (𝛽=.33, p<.001), education level (𝛽=.09, p=.014) and salary satisfaction (𝛽=.09, p=.015) as the influencing factors of job satisfaction, in which the explanatory power for the final model was 78%. Based on the results of this study, it is suggested to develop and verify the effectiveness of programs to improve the positive psychological capital and job crafting of clinical nurses.

Development of Inquiry Activity Materials for Visualizing Typhoon Track using GK-2A Satellite Images (천리안 위성 2A호 영상을 활용한 태풍 경로 시각화 탐구활동 수업자료 개발)

  • Chae-Young Lim;Kyung-Ae Park
    • Journal of the Korean earth science society
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    • v.45 no.1
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    • pp.48-71
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    • 2024
  • Typhoons are representative oceanic and atmospheric phenomena that cause interactions within the Earth's system with diverse influences. In recent decades, the typhoons have tended to strengthen due to rapidly changing climate. The 2022 revised science curriculum emphasizes the importance of teaching-learning activities using advanced science and technology to cultivate digital literacy as a citizen of the future society. Therefore, it is necessary to solve the temporal and spatial limitations of textbook illustrations and to develop effective instructional materials using global-scale big data covered in the field of earth science. In this study, according to the procedure of the PDIE (Preparation, Development, Implementation, Evaluation) model, the inquiry activity data was developed to visualize the track of the typhoon using the image data of GK-2A. In the preparatory stage, the 2015 and 2022 revised curriculum and the contents of the inquiry activities of the current textbooks were analyzed. In the development stage, inquiry activities were organized into a series of processes that can collect, process, visualize, and analyze observational data, and a GUI (Graphic User Interface)-based visualization program that can derive results with a simple operation was created. In the implementation and evaluation stage, classes were conducted with students, and classes using code and GUI programs were conducted respectively to compare the characteristics of each activity and confirm its applicability in the school field. The class materials presented in this study enable exploratory activities using actual observation data without professional programming knowledge which is expected to contribute to students' understanding and digital literacy in the field of earth science.

Anti-inflammatory effects of biorenovated Torreya nucifera extract in RAW264.7 cells induced by Cutibacterium acnes (여드름균에 의해 유도된 RAW264.7 세포에서 생물 전환된 비자나무 추출물의 항염증 효과)

  • Hyehyun Hong;Tae-Jin Park;Yu-Jung Lee;Byeong Min Choi;Seung-Young Kim
    • Journal of Applied Biological Chemistry
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    • v.66
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    • pp.213-220
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    • 2023
  • The most common skin disease, acne, often occurs in adolescence, but it is also detected/observed in adults due to air pollution and drug abuse. One of the causative agents of acne, Cutibacterium acnes (C. acnes) plays a role in the development of skin acne by inducing inflammatory mediators. Torreya nucifera (TN) is an evergreen tree of the family Taxaceae, having well reported antioxidant, anti-proliferative, liver protection, and nerve protection properties. Improvement of these bioactive properties of natural products is one of the purposes of natural product chemistry and pharmaceuticals. We believe biorenovation could be one improvement strategy that utilizes microbial metabolism to produce unique derivatives having enhanced bioactivity. Therefore, in this study, the C. acnes-induced RAW264.7 inflammation model was used to evaluate the anti-inflammatory activity of the biorenovated Torreya nucifera product (TNB). The results showed improved viability of TNB-treated cells compared to TN-treated cells in the concentration range of 50, 100, and 200 ㎍/mL. At non-toxic concentrations, TNB inhibited the production of nitric oxide and prostaglandin E2 by suppression of inducible nitric oxide synthase and cyclooxygenase-2 protein expression. TNB also attenuated the expression of interleukin-1β, interleukin-6, interleukin-8, and tumor necrosis factor-α induced by C. acnes. Furthermore, TNB inhibited the nuclear factor-κB signaling pathway, a transcription factor known to regulate inflammatory mediators. Based on these results, this study suggests the potential of using TNB as natural material for the treatment of acnes and thus, supporting our postulation of biorenovation as an bioactivity improvement strategy.

LC/MS-based metabolomics approach for selection of chemical markers by domestic production region of Schisandra chinensis (오미자(Schisandra chinensis)의 국내 산지별 화학적마커 선정을 위한 LC/MS 기반의 대사체학 접근법)

  • In Seon Kim;Seon Min Oh;Ha Eun Song;Doo-Young Kim;Dahye Yoon;Dae Young Lee;Hyung Won Ryu
    • Journal of Applied Biological Chemistry
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    • v.66
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    • pp.467-476
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    • 2023
  • Schisandra chinensis (S. chinensis) is a deciduous broad-leaved cave plant belonging to the Schisandraceae family and is widely distributed in East Asia including Korea, Japan, China, and Taiwan. It has been reported that the main components contained in S. chinensis include lignan compounds and triterpenoid compounds. To distinguish the characteristics of S. chinensis by production region of Korea, a discriminant was established by performing metabolite profiling and principal component analysis, a multivariate statistical analysis technique. As a result, 16 types of triterpenoids, 9 types of lignan, and 1 type each of flavonoid, phenylpropanoid, and fatty acid were identified. In addition, through multivariate statistical analysis, it was confirmed that the four groups in Danyang, Moongyeong, Geochang, and Pyeongchang were divided, by applying the s-plot model of orthogonal partial least squares discriminant analysis. Biomarkers were identified: lanostane, cycloartane, schiartane triterpenoid, and dibenzocyclo-octadiene lignan were identified as chemical markers, respectively.

Three-dimensional thermal-hydraulics/neutronics coupling analysis on the full-scale module of helium-cooled tritium-breeding blanket

  • Qiang Lian;Simiao Tang;Longxiang Zhu;Luteng Zhang;Wan Sun;Shanshan Bu;Liangming Pan;Wenxi Tian;Suizheng Qiu;G.H. Su;Xinghua Wu;Xiaoyu Wang
    • Nuclear Engineering and Technology
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    • v.55 no.11
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    • pp.4274-4281
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    • 2023
  • Blanket is of vital importance for engineering application of the fusion reactor. Nuclear heat deposition in materials is the main heat source in blanket structure. In this paper, the three-dimensional method for thermal-hydraulics/neutronics coupling analysis is developed and applied for the full-scale module of the helium-cooled ceramic breeder tritium breeding blanket (HCCB TBB) designed for China Fusion Engineering Test Reactor (CFETR). The explicit coupling scheme is used to support data transfer for coupling analysis based on cell-to-cell mapping method. The coupling algorithm is realized by the user-defined function compiled in Fluent. The three-dimensional model is established, and then the coupling analysis is performed using the paralleled Coupling Analysis of Thermal-hydraulics and Neutronics Interface Code (CATNIC). The results reveal the relatively small influence of the coupling analysis compared to the traditional method using the radial fitting function of internal heat source. However, the coupling analysis method is quite important considering the nonuniform distribution of the neutron wall loading (NWL) along the poloidal direction. Finally, the structure optimization of the blanket is carried out using the coupling method to satisfy the thermal requirement of all materials. The nonlinear effect between thermal-hydraulics and neutronics is found during the blanket structure optimization, and the tritium production performance is slightly reduced after optimization. Such an adverse effect should be thoroughly evaluated in the future work.

A Study on the Quality of Healthcare Services for Four Critical Illnesses and the Maintenance of Right to Protection and Dignity in a Senior General Hospital (상급종합병원의 4대 중증질환 의료 서비스 품질과 보호받을 권리 및 존엄성 유지에 관한 연구)

  • Woojin Lee;Minsuk Shin
    • Journal of Korean Society for Quality Management
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    • v.51 no.4
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    • pp.531-550
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    • 2023
  • Purpose: The unique nature of life-and-death healthcare services sets them apart from other service industries. While many studies exist on the relationship between healthcare services and customer satisfaction, most of them focus on mildly ill patients, ignoring the differences between critically ill and non-seriously ill patients. This study discusses the actual quality of healthcare services for patients who are facing life-threatening illnesses and are on life support, as well as their right to protection and dignity. Methods: The survey conducted to 149 patients with the four major illnesses: cancer, heart disease, brain disease and rare and incurable disease, those who have experiences with senior general hospitals. Results: The basic statistics of this study are adequate to represent the four major critical illnesses, and the reliability and validity of this study's hypotheses, which were measured by multiple items, were analyzed, and the internal consistency was judged to be high. In addition, it was found that the convergent validity was good and the discriminant validity was also secured. When examining the goodness of fit of the hypotheses, the SRMR, which is the standardized root mean square of residuals that measures the difference between the covariance matrix of the data variables and the theoretical covariance matrix structure of the model, met the optimal criteria. Conclusion: The academic implications of this study are differentiated from other studies by moving away from evaluating the quality of healthcare services for mildly ill patients and focusing on the rights and dignity of patients with life-threatening illnesses in four senior general hospitals. In terms of academic implications, this study enriches the depth of related studies by demonstrating the right to protection and dignity as a factor of patient-centeredness based on physical environment quality, interaction quality, and outcome quality, which are presented as sub-factors of healthcare quality. We found that the three quality factors classified by Brady and Cronin (2001) are optimized for healthcare quality assessment and management, and that the results of patients' interaction quality assessment can be used to provide a comprehensive quality rating for hospitals. Health and human rights are inextricably linked, so assessing the degree to which rights and dignity are protected can be a superior and more comprehensive measurement tool than traditional health level measures for healthcare organizations. Practical implications: Improving the quality of the physical environment and the quality of outcomes is an important challenge for hospital managers who attract patients with life and death conditions, but given the scale and economics of time, money, and human inputs, improving the quality of interactions and defining them as performance indicators in hospital quality management is an efficient way to create maximum value in the short term.

Amelioration of colitis progression by ginseng-derived exosome-like nanoparticles through suppression of inflammatory cytokines

  • Jisu Kim;Shuya Zhang ;Ying Zhu;Ruirui Wang;Jianxin Wang
    • Journal of Ginseng Research
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    • v.47 no.5
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    • pp.627-637
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    • 2023
  • Background: Damage to the healthy intestinal epithelial layer and regulation of the intestinal immune system, closely interrelated, are considered pivotal parts of the curative treatment for inflammatory bowel disease (IBD). Plant-based diets and phytochemicals can support the immune microenvironment in the intestinal epithelial barrier for a balanced immune system by improving the intestinal microecological balance and may have therapeutic potential in colitis. However, there have been only a few reports on the therapeutic potential of plant-derived exosome-like nanoparticles (PENs) and the underlying mechanism in colitis. This study aimed to assess the therapeutic effect of PENs from Panax ginseng, ginseng-derived exosome-like nanoparticles (GENs), in a mouse model of IBD, with a focus on the intestinal immune microenvironment. Method: To evaluate the anti-inflammatory effect of GENs on acute colitis, we treated GENs in Caco2 and lipopolysaccharide (LPS) -induced RAW 264.7 macrophages and analyzed the gene expression of proinflammatory cytokines and anti-inflammatory cytokines such as TNF-α, IL-6, and IL-10 by real-time PCR (RT-PCR). Furthermore, we further examined bacterial DNA from feces and determined the alteration of gut microbiota composition in DSS-induced colitis mice after administration of GENs through 16S rRNA gene sequencing analysis. Result: GENs with low toxicity showed a long-lasting intestinal retention effect for 48 h, which could lead to effective suppression of pro-inflammatory cytokines such as TNF-α and IL-6 production through inhibition of NF-κB in DSS-induced colitis. As a result, it showed longer colon length and suppressed thickening of the colon wall in the mice treated with GENs. Due to the amelioration of the progression of DSS-induced colitis with GENs treatment, the prolonged survival rate was observed for 17 days compared to 9 days in the PBS-treated group. In the gut microbiota analysis, the ratio of Firmicutes/Bacteroidota was decreased, which means GENs have therapeutic effectiveness against IBD. Ingesting GENs would be expected to slow colitis progression, strengthen the gut microbiota, and maintain gut homeostasis by preventing bacterial dysbiosis. Conclusion: GENs have a therapeutic effect on colitis through modulation of the intestinal microbiota and immune microenvironment. GENs not only ameliorate the inflammation in the damaged intestine by downregulating pro-inflammatory cytokines but also help balance the microbiota on the intestinal barrier and thereby improve the digestive system.

A Study on Metadata Design for Managing Person and Organization Names in the National Debt Redemption Movement Digital Archive (국채보상운동 디지털 아카이브의 개인/단체명 관리를 위한 메타데이터 설계에 관한 연구)

  • Sangeun Han;Seulki Do
    • Journal of the Korean Society for information Management
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    • v.41 no.1
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    • pp.509-536
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    • 2024
  • The purpose of this study is to develop a metadata AP for managing the person and organization name authority data in the National Debt Redemption Movement Digital Archive, a small-scale digital archive. The design principles and core metadata elements were derived by analyzing person/organization(group or corporateBody) metadata standards, implementation practices, and guidelines of libraries and archives, and mapped to the National Debt Redemption Movement person/organization name thesaurus data and the Wikidata Linked Metadata Model, resulting in 10 elements in the identification area, 14 elements in the content area, 8 elements in the relationship area, and 4 elements in the control area. A simple structure schema was applied so that it can be applied even in small organizations, and for interoperability, the schema was proposed with reference to DublinCore and SKOS schemes, and the applicability was confirmed based on actual data. The results of this study can be utilized as a basis for institutions that recognize the importance of data management but have difficulty in applying it in practice, when they want to prepare a system for managing their own authority data.

What Concerns Does ChatGPT Raise for Us?: An Analysis Centered on CTM (Correlated Topic Modeling) of YouTube Video News Comments (ChatGPT는 우리에게 어떤 우려를 초래하는가?: 유튜브 영상 뉴스 댓글의 CTM(Correlated Topic Modeling) 분석을 중심으로)

  • Song, Minho;Lee, Soobum
    • Informatization Policy
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    • v.31 no.1
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    • pp.3-31
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    • 2024
  • This study aimed to examine public concerns in South Korea considering the country's unique context, triggered by the advent of generative artificial intelligence such as ChatGPT. To achieve this, comments from 102 YouTube video news related to ethical issues were collected using a Python scraper, and morphological analysis and preprocessing were carried out using Textom on 15,735 comments. These comments were then analyzed using a Correlated Topic Model (CTM). The analysis identified six primary topics within the comments: "Legal and Ethical Considerations"; "Intellectual Property and Technology"; "Technological Advancement and the Future of Humanity"; "Potential of AI in Information Processing"; "Emotional Intelligence and Ethical Regulations in AI"; and "Human Imitation."Structuring these topics based on a correlation coefficient value of over 10% revealed 3 main categories: "Legal and Ethical Considerations"; "Issues Related to Data Generation by ChatGPT (Intellectual Property and Technology, Potential of AI in Information Processing, and Human Imitation)"; and "Fear for the Future of Humanity (Technological Advancement and the Future of Humanity, Emotional Intelligence, and Ethical Regulations in AI)."The study confirmed the coexistence of various concerns along with the growing interest in generative AI like ChatGPT, including worries specific to the historical and social context of South Korea. These findings suggest the need for national-level efforts to ensure data fairness.

Development of a Prediction Model for Personal Thermal Sensation on Logistic Regression Considering Urban Spatial Factors (도시공간적 요인을 고려한 로지스틱 회귀분석 기반 체감더위 예측 모형 개발)

  • Uk-Je SUNG;Hyeong-Min PARK;Jae-Yeon LIM;Yu-Jin SEO;Jeong-Min SON;Jin-Kyu MIN;Jeong-Hee EUM
    • Journal of the Korean Association of Geographic Information Studies
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    • v.27 no.1
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    • pp.81-98
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    • 2024
  • This study analyzed the impact of urban spatial factors on the thermal environment. The personal thermal sensation was set as the unit of thermal environment to analyze its correlation with environmental factors. To collect data on personal thermal sensation, Living Lab was applied, allowing citizens to record their thermal sensation and measure the temperature. Based on the input points of the collected personal thermal sensation, nearby urban spatial elements were collected to build a dataset for statistical analysis. Logistic regression analysis was conducted to analyze the impact of each factor on personal thermal sensation. The analysis results indicate that the temperature is influenced by the surrounding spatial environment, showing a negative correlation with building height, greenery rate, and road rate, and a positive correlation with sky view factor. Furthermore, the road rate, sky view factor, and greenery rate, in that order, had a strong impact on perceived heat. The results of this study are expected to be utilized as basic data for assessing the thermal environment to prepare local thermal environment measures in response to climate change.