• The korean journal of orthodontics
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• v.54 no.1
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• pp.48-58
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• 2024

Objective: To quantify the effects of midline-related landmark identification on midline deviation measurements in posteroanterior (PA) cephalograms using a cascaded convolutional neural network (CNN). Methods: A total of 2,903 PA cephalogram images obtained from 9 university hospitals were divided into training, internal validation, and test sets (n = 2,150, 376, and 377). As the gold standard, 2 orthodontic professors marked the bilateral landmarks, including the frontozygomatic suture point and latero-orbitale (LO), and the midline landmarks, including the crista galli, anterior nasal spine (ANS), upper dental midpoint (UDM), lower dental midpoint (LDM), and menton (Me). For the test, Examiner-1 and Examiner-2 (3-year and 1-year orthodontic residents) and the Cascaded-CNN models marked the landmarks. After point-to-point errors of landmark identification, the successful detection rate (SDR) and distance and direction of the midline landmark deviation from the midsagittal line (ANS-mid, UDM-mid, LDM-mid, and Me-mid) were measured, and statistical analysis was performed. Results: The cascaded-CNN algorithm showed a clinically acceptable level of point-to-point error (1.26 mm vs. 1.57 mm in Examiner-1 and 1.75 mm in Examiner-2). The average SDR within the 2 mm range was 83.2%, with high accuracy at the LO (right, 96.9%; left, 97.1%), and UDM (96.9%). The absolute measurement errors were less than 1 mm for ANS-mid, UDM-mid, and LDM-mid compared with the gold standard. Conclusions: The cascaded-CNN model may be considered an effective tool for the auto-identification of midline landmarks and quantification of midline deviation in PA cephalograms of adult patients, regardless of variations in the image acquisition method.

• Journal of Physiology & Pathology in Korean Medicine
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• v.37 no.6
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• pp.172-177
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• 2023

In order to deduce the pathogenic factor(PF) diagnosis logic of underlying in pattern identification of Korean medicine, 2,072 cases of DSOM(Diagnosis System of Oriental Medicine) data from May 2005 to April 2022 were collected and analyzed by means of decision tree model(DTM). The entire data were divided into training data and validation data at a ratio of 7:3. The CHAID algorithm was used for analysis of DTM, and then validity was tested by applying the validation data. The decision rules of items and pathways determined from the diagnosis data of Qi Deficiency, Blood Deficiency, Yin Deficiency and Yang Deficiency Pathogenic Factor of DSOM were as follows. Qi Deficiency PF had 7 decision rules and used 5 questions: Q124, Q116a, Q119, Q119a, Q55. The primary indicators(PI) were 'lack of energy' and 'weary of talking'. Blood deficiency PF had 7 decision rules and used 6 questions: Q113, Q84, Q85, Q114, Q129, Q130. The PI were 'numbness in the limbs', 'dizziness when standing up', and 'frequent cramps'. Yin deficiency PF had 3 decision rules and used 2 questions: Q144 and Q56. The PI were 'subjective heat sensation from the afternoon to night' and 'heat sensation in the limbs'. Yang deficiency PF had 3 decision rules and used 3 questions: Q55, Q10, and Q102. The PI were 'sweating even with small movements' and 'lack of energy'. Conclusively, these rules and symptom information to decide the Qi·Blood·Yin·Yang Deficiency PF would be helpful for Korean medicine diagnostics.

• Convergence Security Journal
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• v.24 no.1
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• pp.59-68
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• 2024

With advancements in artificial intelligence technology, intelligent CCTV systems are being deployed across various environments, such as river bridges and construction sites. However, a conflict arises regarding the opening and closing of rooftop access points due to concerns over potential accidents and crime incidents and their role as emergency evacuation spaces. While the relevant law typically mandates the constant opening of designated rooftop access points, closures are often tacitly permitted in practice for security reasons, with a lack of appropriate legal measures. In this context, this study proposes a detection system utilizing intelligent CCTV to respond to emergencies that may occur on rooftops. We develop a system based on the YOLOv5 object detection model to detect assault and suicide attempts by jumping, introducing a new metric to assess them. Experimental results demonstrate that the proposed system rapidly detects assault and suicide attempts with high accuracy. Additionally, through a legal analysis of rooftop access point management, deficiencies in the legal framework regarding rooftop access and CCTV installation are identified, and improvement measures are proposed. With technological and legal improvements, we believe that crime and accident incidents in rooftop environments will decrease.

• BMB Reports
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• v.57 no.6
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• pp.281-286
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• 2024

Adult hippocampal neurogenesis plays a pivotal role in maintaining cognitive brain function. However, this process diminishes with age, particularly in patients with neurodegenerative disorders. While small, non-coding microRNAs (miRNAs) are crucial for hippocampal neural stem (HCN) cell maintenance, their involvement in neurodegenerative disorders remains unclear. This study aimed to elucidate the mechanisms through which miRNAs regulate HCN cell death and their potential involvement in neurodegenerative disorders. We performed a comprehensive microarray-based analysis to investigate changes in miRNA expression in insulin-deprived HCN cells as an in vitro model for cognitive impairment. miR-150-3p, miR-323-5p, and miR-370-3p, which increased significantly over time following insulin withdrawal, induced pronounced mitochondrial fission and dysfunction, ultimately leading to HCN cell death. These miRNAs collectively targeted the mitochondrial fusion protein OPA1, with miR-150-3p also targeting MFN2. Data-driven analyses of the hippocampi and brains of human subjects revealed significant reductions in OPA1 and MFN2 in patients with Alzheimer's disease (AD). Our results indicate that miR-150-3p, miR-323-5p, and miR-370-3p contribute to deficits in hippocampal neurogenesis by modulating mitochondrial dynamics. Our findings provide novel insight into the intricate connections between miRNA and mitochondrial dynamics, shedding light on their potential involvement in conditions characterized by deficits in hippocampal neurogenesis, such as AD.

• Journal of Korean society of Dental Hygiene
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• v.24 no.3
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• pp.219-227
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• 2024

Objectives: The pulp is the center of the tooth containing nerves and blood vessels. The condition in which the pulp becomes inflamed due to caries or periodontitis is called pulpitis. Pulpitis is a difficult-to-treat disease and causes peripheral nerve tissue changes and severe pain; however, the relationship between neuronal activity and voltage-gated sodium channel 1.7 (Nav1.7) expression in the trigeminal ganglion (TG) during pulpitis has not been well studied. In this study, we found that experimentally induced pulpitis activates Nav1.7 expression in the periphery, leading to neuronal overexpression in the TG. Thus, we sought to identify ways to regulate this process. Methods: Acute pulpitis was induced in rat maxillary molars by treating the pulp with allyl isothiocyanate (AITC). Three days later, in vivo optical imaging was used to record and compare neural activities in the TG. Western blotting was used to identify molecular changes in terms of the expression of extracellular signal-regulated kinase (ERK), c-Fos, transient receptor potential ankyrin 1 (TRPA1), and collapsin response mediator protein-2 (CRMP2) in the brain stem. Results: The results confirmed the neurological changes in the TGs of the pulpitis model, and histological and molecular biological evidence confirmed that increased Nav1.7 expression induced by pulpitis leads to pain. Furthermore, selective inhibition of Nav1.7 resulted in changes in neural activity, suggesting that pulpitis induces increased Nav1.7 expression, and that effective control of Nav1.7 could potentially reduce pain. Conclusions: The inhibition of overexpressed Nav1.7 channels may modulate nociceptive signal processing in the brain and effectively control pain associated with pulpitis.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.24 no.1
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• pp.125-132
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• 2024

The purpose of this study is to discover a drone utilization model tailored to local characteristics, propose directions for building a drone demonstration city based on demand surveys for drone activation, and suggest ways to utilize and support a drone application system. First, according to the survey results, there was a high understanding of and necessity for drone demonstration projects, particularly in addressing urban issues, which were deemed to have a significant impact. Second, based on the analysis of priorities and short- and long-term approaches, disaster-related tasks were evaluated as a priority, requiring an approach through medium- to long-term strategies. Third, it was noted that budgetary considerations emerged as the most critical issue during project implementation. Practitioners and experts expressed willingness to actively introduce drone-based technologies into their work when budget and technology were ready. Budgetary constraints were identified as the most significant obstacle to proper implementation, emphasizing the need for resolution. Fourth, the necessity of demand surveys during project development was identified in certain areas. Demand surveys were deemed essential for drone-based demonstration city construction, and a survey indicated that public leadership in this regard was also necessary. Fifth, concerning approaches in specific areas, the field of safety and disaster management was highlighted as the most crucial for application.

• Journal of Korean Library and Information Science Society
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• v.54 no.4
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• pp.415-436
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• 2023

In this study, we aimed to examine the level of implementation of the second comprehensive plan for promoting academic libraries (2019-2023) by analyzing key statistics of academic libraries and gathering perceptions from library staff. We analyzed the changes in major statistical indicators of libraries over the past five years. Additionally, we surveyed library staff to understand their overall perceptions of the plan and their attitudes towards the 17 sub-tasks outlined in it. The analysis of 369 survey responses revealed several key findings. Firstly, most respondents comprehended the plan well and frequently utilized it for developing their libraries' development and implementation plans. Secondly, the IPA results indicated that regardless of the type of university, there should be a continuous focus on facility improvement, teaching-learning support, and expanding access to academic resources. Efforts to develop library policies and strengthen human and financial resources were identified as crucial. Thirdly, four-year universities particularly emphasized the importance of expanding access to international academic resources compared to junior colleges. Conversely, junior colleges perceived foundational skill-building programs and inclusive services as more significant than four-year universities. The application of the IPA diagonal model revealed that the performance levels of all sub-tasks were lower than their perceived importance levels, suggesting the need for strategies to enhance effectiveness in future comprehensive plan formulation.

• Applied Chemistry for Engineering
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• v.35 no.1
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• pp.8-15
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• 2024

In this study, nitrogen plasma treatment was performed in 5, 10, and 15 minutes to improve the tetracycline adsorption performance of activated carbon. All nitrogen plasma-treated activated carbons showed improved tetracycline adsorption compared to untreated activated carbons. The nitrogen functional groups in activated carbon lead to chemisorption with tetracycline via π-π interactions and hydrogen bonding. In particular, in the nitrogen plasma treatment at 80 W and 50 kHz, the activated carbon treated for 10 minutes had the best adsorption performance. At this time, the nitrogen content on the surface of the activated carbon was 2.03% and the specific surface area increased to 1,483 m²/g. As a result, nitrogen plasma treatment of activated carbon improved its physical and chemical adsorption capabilities. In addition, since the adsorption experimental results were in good agreement with the Langmuir isotherm and pseudo-second order model, it was determined that the adsorption of tetracycline on the nitrogen plasma-treated activated carbon was dominated by chemical adsorption through a monolayer. As a result, nitrogen plasma-treated activated carbon can be used as an adsorbent to efficiently remove tetracycline from water due to the synergistic effect of physical adsorption and proactive chemical adsorption.

• Journal of the Korea institute for structural maintenance and inspection
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• v.28 no.1
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• pp.70-81
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• 2024

In this study, Tridimensional Hybrid Isolation System(THIS) was proposed as a vibration isolator for traffic loads, combining vertical and horizontal isolation systems. Its efficacy in improving serviceability for vertical vibration was analytically evaluated. Firstly, for the analysis, the major vibration modes of the existing apartment were identified through eigenvalue analysis for the system and pulse response analysis for the bedroom slab using commercial structural analysis software. Subsequently, a 16-story model with horizontal, vertical and rotational degrees of freedom for each slab was numerically organized to represent the achieved modes. The dynamic analysis for the measured acceleration from an adjacent ground to high-speed railway was performed by state-space equations with the stiffness and damping ratio of THIS as variables. The result indicated that as the vertical period ratio increased, the threshold period ratio where the slab response started to be suppressed varied. Specifically, when the period ratio is greater than or equal to 5, the acceleration levels of all slabs decreased to approximately 70% or less compared to the non-isolated condition. On the other hand, it was ascertained that the influence of damping ratios on the response control of THIS is inconsequential in the analysis. Finally, the improvement in vertical vibration performance of THIS was evaluated according to design guidelines for floor vibration of AIJ, SCI and AISC. It was confirmed that, after the application of THIS, the residential performance criteria were met, whereas the non-isolated structure failed to satisfy them.

• Industry Promotion Research
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• v.9 no.1
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• pp.89-101
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• 2024

The purpose of this study is to examine the relationship between parental/parental attachment and career indecision among college students, and to examine the goodness of fit and influence of variables in a model that assumes that socially imposed perfectionism has an influence on the relationship between parental/parental attachment and career indecision. It's about verification. For this purpose, an online survey was conducted by randomly sampling 250 college students attending 4-year institutions across the country, and data analysis was conducted using a three-stage regression method using SPSS Win 25.0. The analysis results are as follows. First, psychological attachment to parents appears to have a negative effect on career indecision, confirming that the more a stable attachment relationship with parents is formed, the less difficulties in career decision-making. Second, the mediating effect of socially imposed perfectionism was confirmed in the relationship between psychological attachment to parents and career indecision. This shows that the more stable the psychological attachment to the father and mother is formed, the lower the level of socially imposed perfectionism and career indecision. Based on these research results, implications for career counseling practice and follow-up research were discussed.