• Title/Summary/Keyword: Model Course

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A Method of Assigning Weight Values for Qualitative Attributes in CBR Cost Model (사례기반추론 코스트 모델의 정성변수 속성가중치 산정방법)

  • Lee, Hyun-Soo;Kim, Soo-Young;Park, Moon-Seo;Ji, Sae-Hyun;Seong, Ki-Hoon;Pyeon, Jae-Ho
    • Korean Journal of Construction Engineering and Management
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    • v.12 no.1
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    • pp.53-61
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    • 2011
  • For construction projects, the importance of early cost estimates is highly recognized by the project team and sponsoring organization because early cost estimates are frequently a foundation of business decisions as well as a basis for identifying any changes as the project progresses from design to construction. However, it is difficult to accurately estimate construction cost in the early stage of a project due to various uncertainties in construction. To deal with these uncertainties, cost estimates should be made several times over the course of the project. In particular, early cost estimates are essential process for successful project management. For accurate construction cost estimates, it is necessary to compare cost estimates with actual costs based on historical project data. In this context, case-based reasoning (CBR), which is the process of solving new problems based on the solutions of similar past problems, can be considered as an effective method for cost estimating. To obtain this, it is also required to define the attribute similarities and the attribute weights. However, no existing method is capable of determining attribute weights of qualitative variables. Consequently, it has been a well-known barrier of accurate early cost estimates. Using Genetic Algorithms (GA), this research suggests the method of determining the attribute weight of qualitative variables. Based on building project case studies, the proposed methodology was validated.

Studies on the Cellular Immune Response in Animal Model of Arthritis after the Induction of Oral Tolerance (콜라겐으로 경구 관용을 유도한 관절염 동물 모델의 세포 특이적 면역 반응 조사)

  • Min, So-Youn;Hwang, Sue-Yun;Lee, Jae-sun;Kim, Ju-Young;Lee, Kang-Eun;Kim, Kyung-Wun;Kim, Young-Hun;Do, Ju-Ho;Kim, Ho-Youn
    • IMMUNE NETWORK
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    • v.3 no.2
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    • pp.136-144
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    • 2003
  • Oral administration of antigen has long been considered as a promising alternative for the treatment of chronic autoimmune diseases including rheumatoid arthritis (RA), and oral application of type II collagen (CII) has been proven to improve pathogenic symptoms in RA patients without problematic side effects. To further current understandings about the immune suppression mechanisms mediated by orally administered antigens, we examined the changes in IgG subtypes, T-cell proliferative response, and proportion of interleukin (IL)-10 producing Th subsets in a time course study of collagen induced arthritis (CIA) animal models. We found that joint inflammation in CIA mouse peaked at 5 weeks after first immunization with CII, which was significantly subdued in mice pre-treated by repeated oral administration of CII. Orally tolerized mice also showed increase in their serum level of IgG1, while the level of IgG2a was decreased. T-cell proliferation upon CII stimulation was also suppressed in lymph nodes of mice given oral administration of CII compared to non-tolerized controls. When cultured in vitro in the presence of CII, T-cells isolated from orally tolerized mice presented higher proportion of $CD4^+IL-10^+$ subsets compared to non-tolerized controls. Interestingly, such increase in IL-10 producing cells were obvious first in Peyer's patch, then by 5 weeks after immunization, in mesenteric lymph node and spleen instead. This result indicates that a particular subset of T-cells with immune suppressive functions might have migrated from the original contact site with CII to inflamed joints via peripheral blood after 5 weeks post immunization.

Regional Background Levels of Carbon Monoxide Observed in East Asia during 1991~2004 (1991~2004년 동아시아에서 관측한 일산화탄소의 지역적 배경 농도)

  • Kim, Hak-Sung;Chung, Yong-Seung
    • Journal of the Korean earth science society
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    • v.27 no.6
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    • pp.643-652
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    • 2006
  • Data of the carbon monoxide concentration observed in Mt. Waliguan in China (WLG), Ulaan Uul in Mongolia (UUM), Tae-ahn Peninsula in Korea (TAP), and Ryori in Japan (RYO) were analyzed for a long period between 1991 and 2004. The annual average concentration of carbon monoxide was the highest at TAP $(233{\pm}41ppb)$ followed by $RYO(171{\pm}36ppb),\;UUM(155{\pm}26ppb),\;and\;WLG(135{\pm}22ppb)$. The seasonal variations being high in spring and low in summer were observed in other areas of Eastern Asia except WLG. TAP was high in carbon monoxide concentration in all seasons compared to WLG, UUM and RYO and shows wide distribution of concentration in the histogram, which is caused by the influence of large-scale air pollution due to its downwind location close to the East Asian continent, China in particular. Also, our data was compared with data measured at Mauna Loa (MLO) in Hawaii. According to the origin of the isentropic backward trajectory and its transport passage, carbon monoxide concentration observed in TAP was analyzed as follows: continental background airflows (CBG) were $216{\pm}47ppb$; regionally polluted continental airflows (RPC) were $316{\pm}56ppb$; Oceanic background airflows (OBG) were $108{\pm}41ppb$; and Partly perturbed oceanic airflows (PPO) were $161{\pm}6ppb$. The high concentration of carbon monoxide in TAP is due to the airflow from East Asian continent origin rather than that from the North Pacific origin. Especially, RPC which passes through the eastern China appeared to be the highest in concentration in spring, fall, and winter. However, OBG was affected by the North Pacific air mass with a low carbon monoxide concentration in summer. The NOAA satellite images and GEOS-CHEM model simulation confirmed a large-scale air pollution event that was in the course of expansion from southeastern China bound to the Korean Peninsula and the Korea East Sea by way of the Yellow Sea.

A study on the transitional process of clothes in modern Korean women (한국현대여성복식제도(韓國現代女性服飾制度)의 변천과정연구(變遷過程硏究))

  • Nam, Yun-Suk
    • Journal of the Korean Society of Costume
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    • v.14
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    • pp.99-117
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    • 1990
  • The purpose of this study was to investigate the change of clothes in modem Korean women in terms of a socioeconomical background, the introduction to western clothes, and the improvement of clothes between the opening period of ports in the early 1900's and 1960's. In addition, the study investigated how western clothes became popular in a Korean society along with the traditional' Korean clothes, Hanbok. The radical social change since the opening of ports motivated the change in the way of Korean women's thinking, and consequenty the improvement of Hanbok which developed into the clothes-improvement-movement. It was not until 1905 that the improvement of clothes was hotly debated particularly in the matter of abolishing Jangeui and the extreme length of Jeogori and Chima. The Tongchima-Jeogori style which lengthened Jeogori and shortened Chima was widely accepted as everyday wear until the western clothes substituted them after the Independence from Japanese Conquest. As the length of Chima shortened, there occurred a change in Boson and Jipsin as well. There appeared shoes and Gomoosin in place of Jipsin, socks in stead of Boson and were popularized until after the Liberation in 1945. The popularity of Gomoosin diminished markedly with the diversification of shoes styles, due to the improvement of the standard of living with economic development in the 1960's. The traditional Hanbok was gradually differentiated according to the social status, for instance student, teachers, ordinary women, girls and Kisaeng. Especially since the white clothes caused much trouble in washing and sewing, there came into being the movement of wearing colorful clothes. The Movement of abolishing white clothes and promoting of wearing colorful clothes was enforced during the period of Japaness conquest from the 1920's to the Liberation, which consequently stimulated an interest for colors of clothes. The period under the war between 1937 and 1945 was especially noted for the extreme regulation over the clothes. The Japanese government forced each group of women, e.g., girl students, a young women's association, school teachers, and ordinary women and girls, to wear their own uniforms. Also, It recommended the use of Tongchima in stead of long skirts, and buttons in place of Coreum so as to conserve textile encouraging the use of other substitutes to save resources. The western clothes, a model of clothe's improvement was deemed as a symbol of modernization and enjoyed general popularity. The supply of relief clothes after the Korean war accelerated the expansion of western clothes even further and the trend of westernization along with economic progress in the 1960's resulted in wearing of western clothes as everyday dress. The expansion of western clothes as casual wear rapidly diminished wearing of Hanbok which in turn took the position of ceremonial dress worn in special cases only. Hence the Korean women's clothes were dualized into traditional Hanbok and western clothes and the western clothes that stems on its convenience was settled as everyday wear where as the Hanbok appeared as ceremonial dress stressing on ornamental features. As mentioned aboved, we are able to discovered an orientation in the course of transitional process of modern Korean women's clothes admist diversified changes, which is a consistent pursuit of convenience and practicality based upon progmatism. The trend such as this carne into a finale' as women's dress became dualistic in forms of Hanbok and western clothes, and the change since then is supposed to proceed in two forms of dress featuring its own style.

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Study of the Validity Test on the Self-monitoring Scale for Primi-Gravida (초임부를 대상으로 한 자가검색도 척도의 타당도 비교)

  • Lee, Seon-Ah
    • Women's Health Nursing
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    • v.4 no.2
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    • pp.173-186
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    • 1998
  • In this study, both the literary survey as well as empirical research has been executed to test the validity of the scales that measure the construct of self-monitoring scale could not be classified into five factors as Snyder suggested. Many other scholars (Briggs, Cheek and Buss, 1980) suggested 3 different classifications which was accepted by Snyder and Gangestad (1986). John, Cheek and Klohnen (1996) claimed a two-factor classification. As has been discussed, factor analysis is used to prove convergent validity within the factor and discriminant validity between the factors. However, depending on the researchers, many variations in classification of the factors were found and a lack of content and discriminant validity was found in the previous research findings. It is also important to note that Snyder's self-monitoring scale, did not factor-load at over 30 for all 25 items, regardless of how many factors could be classified. According to findings of this study, the self-monitoring scale neither classified as five, three or two factors nor factor loaded as hypothesized. It is also clear that Snyder's self-monitoring scale lack convergent validity as the sub-factors of the scale fail to prove its uni-dimensionality. The A self-monitoring scale not only fail to overcome the problems of Snyder's self-monitoring scale but even lost the attractiveness of the self-monitoring scale. In this study, it was also found that the A self-monitoring scale was not classified as hypothesized in either in a two or three-factor classification. It is, of course, not desirable to use any scale that lacks convergent and discriminant validity even though it has been widely used but also has held a great deal of influence on the field of social psychology. To overcome the shortcomings of Snyder's self-monitoring scale, Lennox and Wolfe(1984) suggested 13 items. This study 1. was dedicated to test the validity and reliability of the scale, in which we found that the data presented in validity as the two factors were classified and loaded as expected. Reliability was also proven by checking Cronbach's alpha for each factor and for the total items. In addition, a confirmatory factor analysis was executed for the 13 items using LISREL 8.12 program to confirm convergent validity in a two-factor classification. The model was fitting and sound ; however, the self-monitoring scale was unfitted and not validated. Thus, it is recommended to use not the original or the abbreviated self-monitoring scale but the 13 items in future studies. It should also be noted that items 7 and 13 should be removed to obtain better uni-dimensionality for the 13 items. These items loaded at over .30, too high for the two factors in the test results of factor analysis. In addition, it is necessary to double-check the cause of two-hold loading at over .30 for the two factors. It could be a problem caused by data or by the scale itself. Therefore, additional studies should follow to better clarify this matter.

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말기암환자 가족에 대한 호스피스 케어의 정보적 지지 제공 효과

  • Kim, Hyeon-Suk
    • Korean Journal of Hospice Care
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    • v.2 no.1
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    • pp.21-40
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    • 2002
  • Cancer is the second leading cause of the death in Korea. Family caregivers of dying patients manifest many psychological and physical symptoms of stress, and they often seek for informational support from health care providers. Unfortunately, however, few systematic studies identify the actual effect of such support on family caregivers. This study, thus, intends to evaluate the effect of informational support for hospice care. One group pretest-posttest design was used, employing the stress-coping model by Cohen and Wills as a conceptual framework. This research was conducted from July 1 to November 15, 1998, initially with 32 subjects sampled from hemato-oncology department of two general hospitals in Seoul, but reduced to 18 at the end due to the untimely death of patients or caregiver's refusal during the course of study. Informational supports were programmed to provide the family caregivers with 8 times of education and counseling as well as 24-hour hot-line for 4 weeks. A booklet that explains the various problems of hospice care was also prepared and distributed to all subjects. Data were collected by using self-report questionnaires and reviewing medical records. The tools used in this study were based on the Weinert's PRQ-II(scale of perceived social support), Spielberger's state anxiety inventory, and CES-D. Also included in the data collection were the general characteristics of family caregivers and patients, and the pain intensity and the performance status of patients. The data were analyzed with descriptive statistics, Wilcoxon sign rank test and paired t-test using SPSSWIN program. The results of the study were as follows: 1.The perceived social support of family caregivers was not significantly increased with informational support for hospice care(t=1.64, one tailed p=.060). 2.The anxiety of family caregivers was significantly reduced following informational support for hospice care(t=3.48, one tailed p=.002). 3.The depression of family caregivers was significantly reduced following informational support for hospice care(t=-2.18, one tailed=.022). 4.The pain intensity of patients with terminal cancer was significantly reduced following informational support for hospice care(t=-2.41, two tailed p=.027). The results suggest that the informational support provided to family caregivers of patients with terminal cancer reduced not only their anxiety and depression but also the pain intensity of patients. Further study is necessary to consolidate the conceptual framework of this study with expanded number of subjects. Nevertheless, it was certain that the informational support program for hospice care was very helpful to both caregivers and patients. Thus, the informational support program is strongly recommended for the hospitals which have no hospice unit yet.

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A Study of School program in the Case of Library and Information Science in Korea (한국문헌정보학의 학부제 도입에 관한 연구)

  • Koo Bon-young
    • Journal of the Korean Society for Library and Information Science
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    • v.30 no.2
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    • pp.3-50
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    • 1996
  • At present, Korean universities and colleges are confronted with a strong challenge, within and without, demanding a drastic change or innovation of university education. Discussion on the propulsion of the School Program is now under way as one of the means to reform the university education With such a background in mind, we have considered what should be the desirable course of Library and Information Science in Korea. We have considered the characteristic features and roles of library and information professionals to cope with the now approaching information society and the changing conditons of educational environment We have collected the pros and cons among professors of tile School Program, and investigated the curricula of the three universities which are at present practicing the School Program. Of the 139 professors to whom we have sent the questionnaries, $92(66\%)$ responded, of which the pros were 42 and the cons were 45. The model plan for the School Program is 'departmental school program' $(44\%)$, which purports to adopt 'departmental school program', with the curricula and material resources being utilized in common, or to adopt joint-appointment system with the common utilization of teaching materials and the introduction of a limited dual major system. The argument against introduction the School Program was that because of the peculiar nature of the discipline itself, Library and Information Science can not be merged with any other discipline.

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Cytokine expression and localization during the development of glomerulosclerosis in FGS mice

  • Park, Sang-Joon;Lee, Sae-Bom;Lee, Young-Ho;Ryu, Si-Yun;Jeong, Kyu-Shik;Lee, Cha-Soo
    • Korean Journal of Veterinary Pathology
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    • v.3 no.1
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    • pp.15-25
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    • 1999
  • To elucidate the mechanism of age-related development in FGS/NgaKIST mice with spontaneous glomerulosclerotic lesion, we examined expression and localization of various cytokine mRNA in the kidney in the progression of diseases. This mouse model is the first to develop spontanously occuring glomerosclerotic lesion in the kidney. In this study, we detected the up-regulation of local cytokine genes such as IL-1$\beta$, IL-2, IL-6, IL-10, TNF-$\alpha$, TGF-$\beta$, and IFN- $\gamma$ in the kidneys. In RT-PCR and Southern blot analysis, we detected gradual expressions of cytokine mRNA of IL-1$\beta$, IL-2, IL-6, IFN- $\gamma$, and TNF $\alpha$ mRNA during the course of disease. Other cytokines including IL -10 and TGF -$\beta$ were found to be appeared the slightly expressed level at 3 to 12 weeks before onset of inflammatory lesion but they are highly expressed at the end-stage of the disease accompaning high proteinurea and wasting. In situ RT-PCR, each cytokine mRNA were specifically localized in a variety of cells including mesangial, endothelial, parietal epithelial, tubular epithelial, arterial muscle cell, and infiltrated inflammatory cells. In addition, TNF - $\alpha$was detected moderately in the visceral and parietal epithelial cell, but weakly in endothelial and mesangial cells, whereas IL-1 $\beta$ and IL -6 were strong in mesangial regions. IL-6 and TNF- $\alpha$ was highly localized in the damaged proximal and collecting tubules. Especially, TGF -$\beta$ mRNA was highly found in mesangial cells within glomerulus and interstitium during the end-stage of this disease.. These results indicate that pro inflammatory cytokines such as IL-1 $\beta$, IL-2, IL-6, and TNF- $\alpha$ were gradually expressed from the early stage of this disease to the end-stage, and that IL-10 and TGF-$\beta$ may be important in the accumulation of extracellular matrix(ECM) within glomerulus and periglomerular fibrosis in the progression of this disease as well as tissue destruction in end-stage of this disease.

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Effects of Replacing Lucerne (Medicago sativa L.) Hay with Fresh Citrus Pulp on Ruminal Fermentation and Ewe Performance

  • Sparkes, J.L.;Chaves, A.V.;Fung, Y.T.E.;van Ekris, I.;Bush, R.D.
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.2
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    • pp.197-204
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    • 2010
  • Two studies were conducted to determine the effects of replacing 30% (% in diet DM) of lucerne (Medicago sativa L.) hay with citrus pulp in Merino ewe diets: i) an in vitro study which measured ruminal fermentation; and ii) an in vivo study in which twelve Merino ewes pre- and post-lambing were fed experimental diets in a cross-over design over 120 days to evaluate effects on ewe performance (i.e. DM intake, average daily gain (ADG) and wool growth). In both the in vitro and in vivo studies, the control treatment consisted of lucerne (91.3% in diet DM), lupins (8.3% in diet DM) and phosphate (0.42% in diet DM), while the citrus pulp treatment consisted of lucerne (57.7% in diet DM), lupins (9.5% in diet DM), phosphate (0.48% in diet DM) and fresh citrus pulp (32.3% in diet DM). Data were analysed using the mixed model procedure of SAS. In the in vitro study, gas production, total volatile fatty acid (VFA) yield, proportion of propionic acid to total VFA and in vitro dry matter digestibility (IVDMD) were higher (p<0.02) in the citrus pulp treatment compared to the control treatment. In contrast, in vitro ammonia production, pH and the acetate to propionate ratio were lower (p<0.03) for the citrus pulp treatment compared to the control treatment. In the in vivo study, DM intake of ewes fed the citrus pulp diet was lower than their control ewe counterparts throughout both the pre- and post-lambing periods (928.9 vs. 1,115.0 g/d pre-; 1,285.0 vs. 1,620.3 g/d post-lambing, p<0.01), however ADG was similar (p = 0.12). Wool growth parameters and lamb performance did not differ (p>0.32) between treatments. In summary, the in vitro study demonstrated that the replacement of 30% of a lucerne diet with fresh citrus pulp improved total VFA yield, increased total gas production and improved IVDMD, while decreasing the production of ammonia, acetic acid and rumen pH. In addition, the in vivo study demonstrated that the replacement of 30% of a lucerne diet with fresh citrus pulp pre- and post-lambing decreased intake but did not affect ewe performance in terms of ADG and wool growth. These findings, of course, would be of significant interest to sheep producers endeavouring to control cost of feed ingredients whilst maintaining productivity.

Curriculum Model in Integrated Practicum of Nursing Management and Community Health Nursing (일 간호대학의 간호환경시스템 통합실습방안 적용;간호관리학과 지역사회간호학의 통합)

  • Lee, Kyung-Ja;Kim, Eui-Sook;Lee, Chung-Yul;Kim, In-Sook;Lee, Tae-Hwa;Cho, Yoon-Hee;Chung, Je-Ne;Lee, Hyun-Jung;Bae, Sun-Hyoung;Kim, Eun-Hyeon;Kim, Gwang-Suk
    • Journal of Korean Academy of Nursing Administration
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    • v.14 no.1
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    • pp.51-62
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    • 2008
  • Purpose: Integrated curriculum has been considered as a desirable method in health related school course. The present study was conducted to develop practice curriculum which integrates nursing management and community health nursing and measure the education effect. Method: Literature review and scores of professional meeting were carried out to generate main educational goals, contents, operating principle, and evaluation item. Student evaluation was done by survey and in-dept interview in right after practicum and three months respectively. Results: Six concepts were derived as main component of the integrated curriculum. From 2 to 3 sub-categories were matched to each main component as well. Subsequently, practice contents were suggested on the basis of sub-categories. Attainment of practicum goal scores ranged from 2.82 to 3.54 in four points index. Students expressed that they found nursing manager's role in the community setting. Conclusion: This new approach encouraged students to ascertain relationship between hospital oriented and community based practice. Additionally, they can be prepared to comprehend diverse health care environment.

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