• Title/Summary/Keyword: Modality

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Radiotherapy as an effective treatment modality for follicular lymphoma: a single institution experience

  • Choi, Seo Hee;Cho, Jaeho;Kim, Jin Seok;Cheong, June-Won;Suh, Chang-Ok
    • Radiation Oncology Journal
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    • v.33 no.4
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    • pp.310-319
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    • 2015
  • Purpose: Follicular lymphoma (FL) is an indolent non-Hodgkin's lymphoma that is highly sensitive to radiotherapy (RT). However, the effectiveness of RT has not been well established. We reviewed our experiences to assess the role of RT for FL and analyze treatment results. Materials and Methods: Retrospective analysis was done on 29 patients who received first RT between January 2003 and August 2013. Of 23 early stage (stage I, II) patients, 16 received RT alone, four received chemotherapy followed by RT, two received RT postoperatively, and one received salvage RT for relapse after resection. Six advanced-stage (stage III, IV) patients received RT after chemotherapy: two received consolidation RT, three received salvage RT for residual lesions, and one received RT for progressive sites. Median RT dose was 30.6 Gy (range, 21.6 to 48.6 Gy). Median follow-up duration was 62 months (range, 6 to 141 months). Results: All patients showed complete response in the radiation field. Eight outfield relapses were reported. Seven patients received salvage treatment (three chemotherapy, four RT). Four patients showed excellent responses, especially to RT. Estimated 5-year and 10-year relapse-free survivals were 72% and 60%. In the RT-alone group, 5-year relapse-free survival was 74.5%. All advanced-stage patients were disease-free with 100% 5-year overall survival. Disease-specific death was noted in only one patient; four others died of other unrelated causes. No significant toxicity was reported. Conclusion: RT resulted in excellent treatment outcomes for all FL stages when used as a primary treatment modality for early stage or salvage-treatment modality for advanced-stage disease.

Spontaneous Resolution of Chronic Subdural Hematoma : Close Observation as a Treatment Strategy

  • Kim, Hyung Chan;Ko, Jung Ho;Yoo, Dong Soo;Lee, Sang-Koo
    • Journal of Korean Neurosurgical Society
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    • v.59 no.6
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    • pp.628-636
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    • 2016
  • Objective : Chronic subdural hematoma (cSDH) is common condition in neurosurgical field. It is difficult to select the treatment modality between the surgical method and the conservative method when patients have no or mild symptoms. The purpose of this study is to provide a suggestion that the patients could be cured with conservative treatment modality. Methods : We enrolled 16 patients who had received conservative treatment for cSDH without special medications which could affect hematoma resolution such as mannitol, steroids, tranexamic acid and angiotensin converting enzyme inhibitors. The patients were classified according to the Markwalder's Grading Scale. Results : Among these 16 patients, 13 (81.3%) patients showed spontaneously resolved cSDH and 3 (18.7%) patients received surgery due to symptom aggravation and growing hematoma. They were categorized into two groups based on whether they were cured with conservative treatment or not. The first group was the spontaneous resolution group. The second group was the progression-surgery group. The mean hematoma volume in the spontaneous resolution group was 43.1 mL. The mean degree of midline shift in the spontaneous resolution group was 5.3 mm. The mean hematoma volume in the progression-surgery group was 62.0 mL. The mean degree of midline shift in the second group was 6 mm. Conclusion : We suggest that the treatment modality should be determined according to the patient's symptoms and clinical condition and close observation could be performed in patients who do not have any symptoms or in patients who have mild to moderate headache without neurological deterioration.

FLIR and CCD Image Fusion Algorithm Based on Adaptive Weight for Target Extraction (표적 추출을 위한 적응적 가중치 기반 FLIR 및 CCD 센서 영상 융합 알고리즘)

  • Gu, Eun-Hye;Lee, Eun-Young;Kim, Se-Yun;Cho, Woon-Ho;Kim, Hee-Soo;Park, Kil-Houm
    • Journal of Korea Multimedia Society
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    • v.15 no.3
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    • pp.291-298
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    • 2012
  • In automatic target recognition(ATR) systems, target extraction techniques are very important because ATR performance depends on segmentation result. So, this paper proposes a multi-sensor image fusion method based on adaptive weights. To incorporate the FLIR image and CCD image, we used information such as the bi-modality, distance and texture. A weight of the FLIR image is derived from the bi-modality and distance measure. For the weight of CCD image, the information that the target's texture is more uniform than the background region is used. The proposed algorithm is applied to many images and its performance is compared with the segmentation result using the single image. Experimental results show that the proposed method has the accurate extraction performance.

Treatment Results of Hypopharyngeal Carcinoma (하인두암의 방사선치료 성적)

  • Lee Chang Gul;Loh John J.K.;Ryu Sam Youl;Park Kyung Ran;Suh Chang Ok;Kim Gew Earn;Hong Won Pyo;Kim Byung Soo
    • Radiation Oncology Journal
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    • v.6 no.1
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    • pp.23-33
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    • 1988
  • A rerospective review of fifty patients with carcinoma of hypopharynx treated with $RT{\pm}surgery$ was studied for eleven-year period from 1974 to 1984. Of the 50 patients,46 were pyriform sinus in origin, 4 were posterior pharyngeal wall. Eighty-eight percent of patients were locoregionally advanced(stage III, IV) and 78% of patients presented conical lymphadenopathy. 5-year disease-free survival rate of the pyriform sinus ca. was $25.4\%$ in RT alone group, $80\%$ in combined modality group and $30.6\%$ in overall. Local control rate with RT alone in early stage (II) was excellent $(100\%)$, however combined modality appears to be better for local control$(80\%)$ in advanced stage (III, IV) as compared with that of RT alone group $(32\%).$ On basis of this study, RT alone is effective in terms of local control and functional preservation in treatment of early stage of pyriform sinus ca. while surgery can be reserved for salvage purpose when RT fails and combined modality is recommended in patients with locally advanced stage for better local control and survival.

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$^{18}$F-Fluoride-PET in Skeletal Imaging ($^{18}$F-Fluoride-PET을 이용한 골격계 영상)

  • Jeon, Tae-Joo
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.4
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    • pp.253-258
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    • 2009
  • Bone scintigraphy using $^{99m}$Tc-labeled phosphate agents has long been the standard evaluation method for whole skeletal system. However, recent shortage of $^{99m}$Tc supply and advanced positron emission tomography (PET) technology evoked the attention to surrogate radiopharmaceuticals and imaging modalities for bone. Actually, fluorine-18 ($^{18}$F) was the first bone seeking radiotracer before the introduction of $^{99m}$Tc-labeled agents even though its clinical application failed to become pervasive anymore after the rapid spread of Anger type gamma camera systems in early 1970s. However, rapidly developed PET technology made us refocus on the usefulness of $^{18}$F as a PET tracer. Early study comparing $^{18}$F-Na PET scan and planar bone scintigraphy reported that PET has higher sensitivity and specificity in the diagnosis of metastatic bone lesions than planar bone scan. Subsequent reports comparing between PET and both planar and SPECT bone image also revealed better results of PET scan in similar study groups. Rapid clinical application of PET/CT also accumulated considerable amount of experiences in skeletal evaluation and this modality is known to have better diagnostic power than stand alone PET system as well as bone scan. Furthermore $^{18}$F-Na PET/CT revealed better or at least equal results in detection of primary and metastatic bone lesions compared with CT and MRI. Therefore, it is obvious that $^{18}$F-Na PET/CT has potential to become new imaging modality for practical skeletal evaluation so continuous and careful evaluation of this modality and radiopharmaceutical must be required.

Comparison of accuracy between panoramic radiography, cone-beam computed tomography, and ultrasonography in detection of foreign bodies in the maxillofacial region: an in vitro study

  • Abdinian, Mehrdad;Aminian, Maedeh;Seyyedkhamesi, Samad
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.44 no.1
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    • pp.18-24
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    • 2018
  • Objectives: Foreign bodies (FBs) account for 3.8% of all pathologies of the head and neck region, and approximately one third of them are missed on initial examination. Thus, FBs represent diagnostic challenges to maxillofacial surgeons, rendering it necessary to employ an appropriate imaging modality in suspected cases. Materials and Methods: In this cross-sectional study, five different materials, including wood, metal, glass, tooth and stone, were prepared in three sizes (0.5, 1, and 2 mm) and placed in three locations (soft tissue, air-filled space and bone surface) within a sheep's head (one day after death) and scanned by panoramic radiography, cone-beam computed tomography (CBCT), and ultrasonography (US) devices. The images were reviewed, and accuracy of the detection modalities was recorded. The data were analyzed statistically using the Kruskal-Wallis, Mann-Whitney U-test, Friedman, Wilcoxon signed-rank and kappa tests (P<0.05). Results: CBCT was more accurate in detection of FBs than panoramic radiography and US (P<0.001). Metal was the most visible FB in all of modalities. US was the most accurate technique for detecting wooden materials, and CBCT was the best modality for detecting all other materials, regardless of size or location (P<0.05). The detection accuracy of US was greater in soft tissue, while both CBCT and panoramic radiography had minimal accuracy in detection of FBs in soft tissue. Conclusion: CBCT was the most accurate detection modality for all the sizes, locations and compositions of FBs, except for the wooden materials. Therefore, we recommend CBCT as the gold standard of imaging for detecting FBs in the maxillofacial region.

Secondary Grammaticalization and English Adverbial Tense (이차적 문법화와 영어부사의 시제)

  • Kim, Yangsoon
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.4
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    • pp.115-121
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    • 2020
  • The primary aim of this paper is to discuss the historical development or grammaticalization of English adverbial -ly suffix and provide a diachronic analysis of manner adverbs and sentence adverbs from the perspective of secondary grammaticalization. The grammaticalization includes both the primary grammaticalization from a lexical to a grammatical and the secondary grammaticalization from a less grammatical to a more grammatical status. The emergence of the manner adverbs is due to the primary grammaticalization from OE adjectival suffix -lic to ME adverbial suffix -ly. In contrast, the emergence of sentence adverbs is due to the secondary grammaticalization from manner adverbs in VP domain to sentence adverbs in TP domain with grammatical features of tense and modality. This paper concludes that the secondary grammaticalization of the English adverbial -ly suffix includes the change from manner adverbs to sentence adverbs which obtain a new grammatical function of tense and modality.

Trend analysis of prosthodontic treatment modality between 2005 and 2008 in Seoul National University Dental Hospital

  • Li, Hongbo;Lee, Jai-Bong;Liu, Hongchen;Han, Jung-Suk;Yang, Jae-Ho;Koak, Jai-Young;Heo, Seong-Joo
    • The Journal of Advanced Prosthodontics
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    • v.2 no.1
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    • pp.4-6
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    • 2010
  • PURPOSE. The aim of this article is to analyze the preference for treatment modality of dentists. MATERIAL AND METHODS. Data of 20,038 patients was involved. Data analysis were done by distribution according to the various kinds of prosthesis, including complete denture, removable partial denture, fixed partial denture, implant-supported dental prosthesis as well as distribution according to the professional titles of the dentists finishing the treatment, including resident and professors. RESULTS. The number of cases of dental prosthesis increased year by year. 61.06% of the patients accepted fixed partial denture restoration. The number of patients who accepted implant supported restoration is also increasing year by year. The number of complete denture, implant-supported dental prosthesis finished by professors was larger than that done by residents, while it was contrary for removable partial denture, fixed partial denture, and the difference was statistically significant (P < .05). CONCLUSION. Professors and residents have some difference in the categorization of prosthesis finished. Fixed partial denture and implant-supported dental prosthesis are preferred.

Reliability of two different presurgical preparation methods for implant dentistry based on panoramic radiography and cone-beam computed tomography in cadavers

  • Hu, Kyung-Seok;Choi, Da-Yae;Lee, Won-Jae;Kim, Hee-Jin;Jung, Ui-Won;Kim, Sung-Tae
    • Journal of Periodontal and Implant Science
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    • v.42 no.2
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    • pp.39-44
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    • 2012
  • Purpose: Special care is necessary to avoid invading important anatomic structures during surgery when presurgical planning is made based on radiographs. However, none of these types of radiography represents a perfect modality. The purpose of this study was to determine the reliability of presurgical planning based on the use of two types of radiographic image (digital panoramic radiography [DPR] and cone-beam computed tomography [CBCT]) by beginner dentists to place implants, and to quantify differences in measurements between radiographic images and real specimens. Methods: Ten fresh cadavers without posterior teeth were used, and twelve practitioners who had no experience of implant surgery performed implant surgery after 10 hours of basic instruction using conventional surgical guide based on CBCT or DPR. Two types of measurement error were evaluated: 1) the presurgical measurement error, defined as that between the presurgical and postsurgical measurements in each modality of radiographic analysis, and 2) the measurement error between postsurgical radiography and the real specimen. Results: The mean presurgical measurement error was significantly smaller for CBCT than for DPR in the maxillary region, whereas it did not differ significantly between the two imaging modalities in the mandibular region. The mean measurement error between radiography and real specimens was significantly smaller for CBCT than for DPR in the maxillary region, but did not differ significantly in the mandibular region. Conclusions: Presurgical planning can be performed safely using DPR in the mandible; however, presurgical planning using CBCT is recommended in the maxilla when a structure in a buccolingual location needs to be evaluated because this imaging modality supplies buccolingual information that cannot be obtained from DPR.