Browse > Article
http://dx.doi.org/10.3340/jkns.2016.59.6.628

Spontaneous Resolution of Chronic Subdural Hematoma : Close Observation as a Treatment Strategy  

Kim, Hyung Chan (Department of Neurological Surgery, College of Medicine, Dankook University)
Ko, Jung Ho (Department of Neurological Surgery, College of Medicine, Dankook University)
Yoo, Dong Soo (Department of Radiology, College of Medicine, Dankook University)
Lee, Sang-Koo (Department of Neurological Surgery, College of Medicine, Dankook University)
Publication Information
Journal of Korean Neurosurgical Society / v.59, no.6, 2016 , pp. 628-636 More about this Journal
Abstract
Objective : Chronic subdural hematoma (cSDH) is common condition in neurosurgical field. It is difficult to select the treatment modality between the surgical method and the conservative method when patients have no or mild symptoms. The purpose of this study is to provide a suggestion that the patients could be cured with conservative treatment modality. Methods : We enrolled 16 patients who had received conservative treatment for cSDH without special medications which could affect hematoma resolution such as mannitol, steroids, tranexamic acid and angiotensin converting enzyme inhibitors. The patients were classified according to the Markwalder's Grading Scale. Results : Among these 16 patients, 13 (81.3%) patients showed spontaneously resolved cSDH and 3 (18.7%) patients received surgery due to symptom aggravation and growing hematoma. They were categorized into two groups based on whether they were cured with conservative treatment or not. The first group was the spontaneous resolution group. The second group was the progression-surgery group. The mean hematoma volume in the spontaneous resolution group was 43.1 mL. The mean degree of midline shift in the spontaneous resolution group was 5.3 mm. The mean hematoma volume in the progression-surgery group was 62.0 mL. The mean degree of midline shift in the second group was 6 mm. Conclusion : We suggest that the treatment modality should be determined according to the patient's symptoms and clinical condition and close observation could be performed in patients who do not have any symptoms or in patients who have mild to moderate headache without neurological deterioration.
Keywords
Close observation; Chronic subdural hematoma; Treatment;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Baldawa SS, Nayak N : Spontaneous resolution of bilateral chronic subdural hematoma. Turk Neurosurg 25 : 835-836, 2015
2 Berghauser Pont LM, Dirven CM, Dippel DW, Verweij BH, Dammers R : The role of corticosteroids in the management of chronic subdural hematoma : a systematic review. Eur J Neurol 19 : 1397-1403, 2012   DOI
3 Delgado-Lopez PD, Martin-Velasco V, Castilla-Diez JM, Rodriguez-Salazar A, Galacho-Harriero AM, Fernandez-Arconada O : Dexamethasone treatment in chronic subdural haematoma. Neurocirugia (Astur) 20 : 346-359, 2009   DOI
4 Ducruet AF, Grobelny BT, Zacharia BE, Hickman ZL, DeRosa PL, Andersen KN, et al. : The surgical management of chronic subdural hematoma. Neurosurg Rev 35 : 155-169; discussion 169, 2012   DOI
5 Fujisawa H, Ito H, Kashiwagi S, Nomura S, Toyosawa M : Kallikrein-kinin system in chronic subdural haematomas : its roles in vascular permeability and regulation of fibrinolysis and coagulation. J Neurol Neurosurg Psychiatry 59 : 388-394, 1995   DOI
6 Glover D, Labadie EL : Physiopathogenesis of subdural hematomas. Part 2 : inhibition of growth of experimental hematomas with dexamethasone. J Neurosurg 45 : 393-397, 1976   DOI
7 Goksu E, Akyuz M, Ucar T, Kazan S : Spontaneous resolution of a large chronic subdural hematoma : a case report and review of the literature. Ulus Travma Acil Cerrahi Derg 15 : 95-98, 2009
8 Greenberg MS : Handbook of Neurosurgery, ed 7. New York : Thieme, 2010, pp899-902
9 Horikoshi T, Naganuma H, Fukasawa I, Uchida M, Nukui H : Computed tomography characteristics suggestive of spontaneous resolution of chronic subdural hematoma. Neurol Med Chir (Tokyo) 38 : 527-532; discussion 532-533, 1998   DOI
10 Jukovic M, Kojadinovic Z, Popovska B, Till V : Complete spontaneous resolution of compressive chronic subdural hematoma in a patient with liver failure. Med Glas (Zenica) 9 : 417-420, 2012
11 Kageyama H, Toyooka T, Tsuzuki N, Oka K : Nonsurgical treatment of chronic subdural hematoma with tranexamic acid. J Neurosurg 119 : 332-337, 2013   DOI
12 Lee GS, Park YS, Min KS, Lee MS : Spontaneous resolution of a large chronic subdural hematoma which required surgical decompression. J Korean Neurosurg Soc 58 : 301-303, 2015   DOI
13 Lee JY, Ebel H, Ernestus RI, Klug N : Various surgical treatments of chronic subdural hematoma and outcome in 172 patients : is membranectomy necessary? Surg Neurol 61 : 523-527; discussion 527-528, 2004   DOI
14 Lee TS, Yang DD, Sung KW, Kim JO, Lee WH, Rhee HY : Two cases of spontaneously absorbed chronic subdural hematoma. J Korean Neurosurg Soc 15 : 861-866, 1986
15 Lieber RL : Statistical significance and statistical power in hypothesis testing. J Orthop Res 8 : 304-309, 1990   DOI
16 Marcikic M, Hreckovski B, Samardzic J, Martinovic M, Rotim K : Spontaneous resolution of post-traumatic chronic subdural hematoma : case report. Acta Clin Croat 49 : 331-334, 2010
17 Markwalder TM : Chronic subdural hematomas : a review. J Neurosurg 54 : 637-645, 1981   DOI
18 Markwalder TM, Steinsiepe KF, Rohner M, Reichenbach W, Markwalder H : The course of chronic subdural hematomas after burr-hole craniostomy and closed-system drainage. J Neurosurg 55 : 390-396, 1981   DOI
19 Naganuma H, Fukamachi A, Kawakami M, Misumi S, Nakajima H, Wakao T : Spontaneous resolution of chronic subdural hematomas. Neurosurgery 19 : 794-798, 1986   DOI
20 Miranda LB, Braxton E, Hobbs J, Quigley MR : Chronic subdural hematoma in the elderly : not a benign disease. J Neurosurg 114 : 72-76, 2011   DOI
21 Nakamura N, Ogawa T, Hashimoto T, Yuki K, Kobayashi S : [Reevaluation on resolving subdural hematoma (author's transl)]. Neurol Med Chir (Tokyo) 21 : 491-500, 1981   DOI
22 Parlato C, Guarracino A, Moraci A : Spontaneous resolution of chronic subdural hematoma. Surg Neurol 53 : 312-315; discussion 315-317, 2000   DOI
23 Sim YW, Min KS, Lee MS, Kim YG, Kim DH : Recent changes in risk factors of chronic subdural hematoma. J Korean Neurosurg Soc 52 : 234-239, 2012   DOI
24 Weigel R, Hohenstein A, Schlickum L, Weiss C, Schilling L : Angiotensin converting enzyme inhibition for arterial hypertension reduces the risk of recurrence in patients with chronic subdural hematoma possibly by an antiangiogenic mechanism. Neurosurgery 61 : 788-792; discussion 792-793, 2007   DOI
25 Sun TF, Boet R, Poon WS : Non-surgical primary treatment of chronic subdural haematoma : preliminary results of using dexamethasone. Br J Neurosurg 19 : 327-333, 2005   DOI
26 Suzuki J, Takaku A : Nonsurgical treatment of chronic subdural hematoma. J Neurosurg 33 : 548-553, 1970   DOI
27 Wang D, Li T, Tian Y, Wang S, Jin C, Wei H, et al. : Effects of atorvastatin on chronic subdural hematoma : a preliminary report from three medical centers. J Neurol Sci 336 : 237-242, 2014   DOI
28 Weir B : The osmolality of subdural hematoma fluid. J Neurosurg 34 : 528-533, 1971   DOI