• Journal of Life Science
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• v.31 no.7
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• pp.686-697
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• 2021

Propolis is a resinous substance produced by honeybees, which they use to protect their hives. Honeybees produce propolis by mixing exudates from the various trees and plants with saliva and beeswax. It has been used since around 300 B.C. as a folk medicine to cure wounds. Propolis contains many physiologically active components, such as flavonoids, phenolic compounds, and beeswax. Because of its functional components, propolis has a wide spectrum of biological applications. The compounds in propolis and its biological activity can vary according to the location of nectar source and extraction method. Propolis is most commonly known for its anti-microorganism activity against bacteria, viruses, and fungi. Artepillin C and caffeic acid phenethyl ester (CAPE) have been identified as regulatory compounds that reduce inflammation and exert immunosuppressive reactions on T lymphocytes. Through its anti-inflammatory activity, propolis exhibits anti-tumor activity, including the inhibition of cancer cell proliferation, the blocking of tumor signaling cascades, and antiangiogenesis. However, for the more apply of propolis its analysis of nectar source, identifying of propolis compound, the molecular mechanism of propolis and the investigation of compounds synergistic effects are essential. In this study, we described the physiological activity of propolis isolated from honeybees.

• Journal of the Korean Geotechnical Society
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• v.34 no.12
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• pp.71-82
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• 2018

This study presents a reasonable and economical DCM reinforcement length for the various factors (the embankment height, the distance from the embankment to the underground structure, the depth of the soft ground, and the compression index and the swelling index of the soft ground) that affect the stability of the structure due to lateral movement. Based on these results, we analyzed each factor's degree of influence and figured out which factor influenced the lateral movement most. The cross section of the embankment on the soft ground was modeled by using the Finite Element Program and reinforced with DCM. The results show that the increase rate of the reinforcement length with the increase of the embankment height is about 9~50%, the increase rate of the reinforcement length with the depth of soft ground is about 13~30%, and the increase rate of the reinforcement length with increasing compression index is about 3~25%. In addition, the influence of each factor on each other was analyzed. As a result, among the separation distance, the compressive index and the maximum to minimum slope ratio of the reinforcement length of the embankment height, the separation distance was the largest for the depth of soft ground. As the depth of the soft ground increases, the ratio of the maximum to minimum slope of the reinforcement length according to the embankment height is 3.75, the ratio of the maximum to minimum slope of the reinforcement length according to the spacing distance is 4.3, and the ratio of maximum to minimum slope according to compression index is 2.5. From these results, it is confirmed that the three factors are greatly affected by the depth of soft ground.

• Korean Chemical Engineering Research
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• v.57 no.1
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• pp.65-72
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• 2019

In this study, heterogeneous ion exchange membranes were prepared by casting method with various mixing ratios of PPO ion-selective solution and ion exchange resin. Then heterogeneous bipolar membranes were prepared by using this. The water content of heterogeneous cation and anion exchange membranes were 60~80% respectively, the ion exchange capacity was 2.81~3.26 meq/g, 2.31~2.74 meq/g and electrical resistances were $1.65{\sim}1.45{\Omega}{\cdot}cm^2$ and $1.55{\sim}1.05{\Omega}{\cdot}cm^2$. The tensile strength of heterogeneous bipolar membrane was lower than that of PPO resin before functionalization ($700Kg_f/cm^2$). The tensile strength of heterogeneous bipolar membrane with catalyst layer was lower than that of non-catalytic heterogeneous bipolar membrane. The water splitting voltage of the heterogeneous bipolar membrane with catalyst layer was low and stable at a minimum of 1.7~1.8 V, maximum 3.9~4.0 V, and the water splitting voltage of the non-catalytic heterogeneous bipolar membrane was constant at 3.8~4.0 V.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.3
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• pp.150-159
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• 2019

The bond analysis model equation was proposed through the regression analysis of the experimental values of bond behavior for each rebar. In order to verify the appropriateness of the bond analysis model equation, the bond behaviors calculated by the proposed bond analysis model, BPE model and CMR model were compared with experimental values. The proposed bond model showed the closest behavior to the experimental values when compared to other analysis models. The former models can not consider the different properties of GFRP rebar according to composed materials, mixing and manufacturing method and the latter has limitation to express the relationships between bond behavior because of derived formula by numerical analysis. This study proposed the analytical model different considering bond mechanism according to surface type. In order to verity the appropriateness of the bond analytical model, the bond behaviors calculated by the proposed bond analytical model, BPE model and CMR model were compared with experimental values. The proposed bond model showed the closest behavior to the experimental values when compared to other analysis models.

• Korean Journal of Heritage: History & Science
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• v.49 no.4
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• pp.114-125
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• 2016

Lacquer is one of the most widely used natural resin in East Asia since Neolithic Age. As a major ingredient of lacquerware, lacquer is waterproof, insect-proof and rot-proof to be durable and anti-abrasion, generally utilized for mainly painting purpose. According to lacquerware excavated from several sites of Japan and China, lacquerware seems to appear in Neolithic Age. On the other hand in case of excavation research in Korea, lacquerwares are found after the Bronze Age. The initial purpose of lacquer is estimated to be adhesive, regarding the literatures mentioning bitumen(Yeoksceong ), animal glue(Kyeo) and egg alumen(Nanbaek). Especially piece of jar coffin unearthed in Pyeongtaek Daechu-ri site had trace of restoration by lacquer and hemp as an evidence of lacquer for adhesion in Pre-Three Kingdoms period. Since then a trend to restore the broken ceramics with lacquer and decorate with golden foil lasted especially in Joseon Dynasty. In the field of gold plated lacquer method, mother-of-pearl inlaying technique for lacquerware and restoration of buildings, lacquer is still used as adhesive. Due to matter of reversibility lacquer is being avoided for conservation and restoration of cultural heritage. Lacquer as a traditional material for adhesive since ancient times, however, has advantage in adhesion strength and durability. Because synthetic resin adhesive has problem of emission of volatile organic compounds and aging over time, lacquer receives attention recently. On the contrary, by combination adhesive from mixing lacquer and animal glue, already proved the possibility of applicability and chemical modification. A research to utilize lacquer as modern paint or functional material is also conducted continuously also in China and Japan. To put traditional material into practical use and modernize, chemical research from the molecular level of the lacquer is necessary in the near future.

• Korean Journal of Medicinal Crop Science
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• v.27 no.4
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• pp.247-258
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• 2019

Background: Astragali radix (A) and Lithospermi radix (L) have long been used as traditional medicines due to their known anti-inflammatory effects. This study aimed at evaluating, their optimal mixing ratio and their functional compounds by investigating the inhibitory effects of mixed extracts of A and L and their active compounds on matrix metalloproteinases (MMPs). Methods and Results: A and L extracts were obtained by extraction at $80^{\circ}C$ using 50% and 70% fermented alcohol, respectively, and then mixed at a ratio of 5 : 5, 6 : 4, 7 : 3 and 8 : 2 (w/w). The activities of MMP-1, MMP-3, and MMP-13 were evaluated in interleukin-1beta ($IL-1{\beta}$)-induced SW1353 cells. The extract mixtures showed synergistic inhibitory effects on MMP-3 and MMP-13, higher than the effects of the individual A and L extracts. The 7 : 3 mixture (ALM16) showed the most effective MMPs inhibitory activity, while among the active ingredients, calycosin-7-O-${\beta}$-D-glucoside and lithospermic acid exhibited excellent MMPs inhibitory activity. Additionally, an HPLC method was established for simultaneous quantification of the effective components of the extract mixtures, and validated by measuring the linearity, precision and accuracy of the limit of detection (LOD) and limit of quantification (LOQ). Conclusions: ALM16 showed the most effective MMPs inhibitory activity. Calycosin-O-${\beta}$-D-glucoside, calycosin and lithospermic acid were identified as useful candidates, as they were the major functional compounds in the MMP inhibitory activity. Summarily, ALM16 might be a highly effective in osteoarthritis management, owing to its because it exhibits a protective effect on cartilage via excellent inhibition of MMPs.

• Journal of Korean Tunnelling and Underground Space Association
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• v.21 no.3
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• pp.433-452
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• 2019

This study deals with shotcrete reinforcing performance according to the amount of synthetic fiber (PP fiber) and proper evaluation method. The shotcrete compressive strength, flexural strength and flexural toughness were tested by setting the mixing amounts of steel fiber ($37.0kg/m^3$) and synthetic fiber (PP fiber) as parameters ($5.0kg/m^3$, $7.0kg/m^3$ and $9.0kg/m^3$). Particularly, circular panel flexural toughness test (Road and Traffic Authority, RTA) was performed to evaluate the shotcrete energy absorption capacity. As a result, the compressive strength and the bending strength of the steel fiber reinforced shotcrete were large, but the flexural toughness of the synthetic fibe (PP fiber) reinforced shotcrete was large. Therefore, synthetic fiber (PP fiber) reinforced shotcrete is considered to have a reinforcing effect comparable to that of steel fiber reinforced shotcrete. Analysis of the relationship between the flexural toughness and the energy absorption capacity of synthetic fiber (PP fiber) reinforced shotcrete revealed that the energy absorbing ability is exhibited at a flexural toughness lower than the allowable standard (3.0 MPa). (Class A: 2.55 MPa = 202J, Class B: 2.72 MPa = 282J, Class C: 3.07 MPa = 403J). As a result of this study, it can be concluded that the actual shotcrete support performance can be evaluated by evaluating the support performance of the shotcrete measured at less than the allowable standard (3.0 MPa) at the actual tunnel site.

• Journal of the Korean Society of Radiology
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• v.14 no.7
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• pp.907-913
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• 2020

There have been continuous controversies on medical X-ray protection and numerous researchers have been trying to prevent unnecessary exposure to radiation. As X-ray passes through the patient and obtains an image, it creates scattered ray due to interactions such as photoelectric effect and Compton scattering with the subject. As a result, both medical radiation staff and patient are exposed to unnecessary radiation on areas other than the target area. In response, this study will be assuming a body of a female, radiating X-ray on the phantom under the conditions of lumbar spine AP test, and measuring scattered ray around breasts and thyroid glands. Then, The experiment results were as follows. After application of non-shielding material, the average of scattered ray was 0.88 mR in thyroid measurement, 3.34 mR, Lt Axillary 3.54 mR, and Rt Axillary 3.03 mR in mamonary measurement but, After application of shielding material, the average of scattered ray was 0.16 mR in thyroid measurement, 0.60 mR, Lt Axillary 0.64 mR, and Rt Axillary 0.54 mR in mamonary measurement showing average scattered ray protection effect of about 82%. This study suggested the manufacturing method of a Jelly-type shielding material, identified the possibilities of researches on mixing various substances with radiology field, and verified the usability of the Jelly-type shielding material as a substitute for existing protection tools.

• (The) Research of the performance art and culture
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• no.18
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• pp.283-314
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• 2009

This paper is an attempt to examine historical drama which change rapidly in the manner of seeing history. Historical records are treated differently unlike in the field of modern history. Now the distinction between historical facts and fictions becomes no longer important. This change is affected by micro history, new cultural history, or post-modern history. History and narrative become interactive each other. In this respect they are no more historical drama. by Han Areum (director Suh Jae-hyung) represents this new trends. Of course, it doesn't suddenly pop up in 2005. It began in by Lee Yoon-Taek, was reinforced in by Kim Tae-Woong, and bloomed in . I intended to search important features of by following three. First is the interest about unimportant persons such as a maid of honor, an eunuch. In , they are the main characters. The author described much about those trivial people revealing the truth in different way of the existence. Second is the way of calling a past. In this piece, the past is not continuous. The past always appears at the stage by the present in the form of split which is imagination, recollection, revival. Third is a mixing genre. Comics, melodrama, and thrillers are all together in . This is a similar phenomenon to historical novel and movie of new trend. Strictly speaking, this piece isn't a history thriller. The accident of lost prince doesn't be treated importantly and the result isn't clear either. In this piece, detective genre is used for a symbol showing that writer pursuits the history, not the event. This represents well the characters of new historical drama because how historical facts are carefully recreated and constructed are important. It's enough to show the possibility to mix genre through comics and melodrama.

• Journal of the Korean Wood Science and Technology
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• v.49 no.4
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• pp.315-327
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• 2021

Purpose of this study is reviewing the use method for the sawdust (sawmilling by-product) and rice husk (Agriculture by-product) by adding charcoal, an eco-friendly material. Mixed composite boards were manufactured with those materials with each density and mixing ratio, and bending performance was investigated. When the addition ratio of sawdust, rice husk and charcoal is 50:20:20 and the resin addition ratio is 10%, as the density of the prepared mixed board ranges from 0.5 g/cm³ to 0.7 g/cm³, the bending strength was 0.42~3.24 N/mm², dynamic modulus of elasticity was 94.5~888.4 N/mm², and the static modulus of elasticity was in the range of 31.4~220.7 N/mm². As the density increased, the bending performance increased, indicating that the density had a significant effect on the bending performance. In a board prepared by setting the density of 0.6 g/cm³, the addition ratio of sawdust to 50%, and the addition ratio of rice husk and charcoal at different ratios, the bending performance showed a tendency to decrease as the addition ratio of charcoal increased. The relationship between the addition ratio of rice husk and charcoal, bending strength, resonance frequency, and dynamic and static bending modulus showed a rather low correlation with the values of the coefficient of determination (R²) of 0.4562, 0.4310, 0.4589, and 0.5847, respectively. Thus, we found that the effect of the addition ratio on the bending performance was small.