• Title/Summary/Keyword: Mixed-effect model

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A comparison study on coupled thermal, hydraulic, and mechanical interactions associated with an underground radwaste repository within a faulted granitic rock mass (화강암반내 단층지역에 위한 지하 방사성폐기물 처분장 인접지역에서의 열-수리-역학적 연성거동 비교 연구)

  • 김진웅;배대석;강철형
    • The Journal of Engineering Geology
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    • v.11 no.3
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    • pp.255-267
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    • 2001
  • A comparison study is performed to understand the coupling behavior of the thermal, hydraulic, and mechanical interactions in the vicinity of an underground radwaste repository, assumed to be located at a depth of 500 m, within a granitic rock mass with a 58$^{\circ}$ dipping fault passing through the roof-wall intersection of the repository cavern. The two dimensional universal distinct element code, UDEC is used for the analysis. The model includes a granitic rock meas, a canister with PWR spent fuels surrounded by the compacted bentonite inside a deposition hole, and the mixed bentonite backfilled in the rest of the space within a repository cavern. The coupling behavior of hydromechanical, thermomechanical, and thermohydromechanical interaction has been studied and compared. The effect of the time-dependent decaying heat, from the radioactive materials in PWR spent fuels, on the repository and its surroundings has been studied. A steady state flow algorithm is used for the hydraulic analysis.

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Formation of SiC Particle Reinforced Al Metal Matrix Composites by Spray Forming Process(I. Microstructure) (분사성형법에 의한 SiC입자강화 알루미늄 복합재료의 제조 I. 미세조직에 대한 고찰)

  • Park, Jong-Sung;Kim, Myung-Ho;Bae, Cha-Hurn
    • Journal of Korea Foundry Society
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    • v.13 no.4
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    • pp.369-381
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    • 1993
  • Aluminum alloy(AC8A) matrix composites reinforced with SiC particles(10% in vol.) were fabricated by Centrifugal Spray Deposition(CSD) process. The microstructures were investigated in order to evaluate both the mixing mode between aluminum matrix and SiC particles, and the effect of SiC particles on the cooling behaviours of droplets during flight and preforms deposited. A non-continuum mathematical calculation was performed to explain and to quantify the evolution of microstructures in the droplets and preforms deposited. Conclusions obtained are as follows; 1. The powders produced by CSD process showed, in general, ligament type, and more than 60% of the powders produced were about 300 to 850 um in size. 2. AC8A droplets solidified during flight showed fine dendritic structure, but AC8A droplets mixed with SiC particles showed fine equiaxed grain structure, and eutectic silicon were formed to crystallize granularly between fine aluminum grains. 3. SiC particles seem to act as a nucleation sites for pro-eutectic silicon during solidification of AC8A alloy. 4. The microstructure of composite powders formed by CSD process showed particle embedded type, and resulted in dispersed type microstructure in preforms deposited. 5. The pro-eutectic silicon crystallized granularly between fine aluminum grains seem to prohibit grains from growth during spray deposition process. 6. The interfacial reactions between aluminum matrix and SiC particles were not observed from the deposit performs and the solidified droplets. 7. The continuum model seem to be useful in connecting the processing parameters with the resultant microstructures. From these results, it was concluded that the fabrication of aluminum matrix composites reinforced homogeneously with SiC particles was possible.

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The Dopamine D4 Receptor Polymorphism Affects the Canine Fearfulness

  • Lee, Chae-Young;Kim, Chang-Hoon;Shin, Soo-An;Shin, Dae-Sung;Kang, Joo-Hyun;Park, Chan-Kyu
    • Animal cells and systems
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    • v.12 no.2
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    • pp.77-83
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    • 2008
  • The canine fearfulness is a behavioral trait known to have a genetic basis. This research analyzed genetic effects of the dopamine D4 receptor polymorphism on this behavior by postulating a mixed model of inheritance. Genotyping for the three different repeat polymorphism found in the third exon of the receptor gene was carried out for the population of the Korean native dogs. Four hundred fifty eight dogs with known pedigree were genotyped, and 264 individuals were tested for their fear responses to an experimenter, in which four different behavioral paradigms were adopted. Since the results assessed by principal factor analysis revealed a major factor explaining 69% of the total phenotypic variance, the subsequent analyses were conducted for this quantity. Analyses of the factor scores by estimating their posterior means indicated that there is a fixed effect exerted by the three different repeat polymorphism found in the D4 receptor as well as sex, in addition to unidentified polygenic effects. The phenotypic contribution of the D4 genotype was roughly estimated to be about 2%, which is a fraction of the total genetic effects responsible for more than 20% of the total phenotypic variance.

Robust market-based control method for nonlinear structure

  • Song, Jian-Zhu;Li, Hong-Nan;Li, Gang
    • Earthquakes and Structures
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    • v.10 no.6
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    • pp.1253-1272
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    • 2016
  • For a nonlinear control system, there are many uncertainties, such as the structural model, controlled parameters and external loads. Although the significant progress has been achieved on the robust control of nonlinear systems through some researches on this issue, there are still some limitations, for instance, the complicated solving process, weak conservatism of system, involuted structures and high order of controllers. In this study, the computational structural mechanics and optimal control theory are adopted to address above problems. The induced norm is the eigenvalue problem in structural mechanics, i.e., the elastic stable Euler critical force or eigenfrequency of structural system. The segment mixed energy is introduced with a precise integration and an extended Wittrick-Williams (W-W) induced norm calculation method. This is then incorporated in the market-based control (MBC) theory and combined with the force analogy method (FAM) to solve the MBC robust strategy (R-MBC) of nonlinear systems. Finally, a single-degree-of-freedom (SDOF) system and a 9-stories steel frame structure are analyzed. The results are compared with those calculated by the $H{\infty}$-robust (R-$H{\infty}$) algorithm, and show the induced norm leads to the infinite control output as soon as it reaches the critical value. The R-MBC strategy has a better control effect than the R-$H{\infty}$ algorithm and has the advantage of strong strain capacity and short online computation time. Thus, it can be applied to large complex structures.

Determination of Factors in Cultural Dimensions and SERVQUAL Model Affecting the Corporate Image of Pharmacy Retail Stores

  • KLONGTHONG, Worasak;THAVORN, Jakkrit;WATCHARADAMRONGKUN, Suntaree;NGAMKROECKJOTI, Chittipa
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.10
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    • pp.875-884
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    • 2020
  • Thailand has a rapidly growing pharmaceutical sector, which is the eighth largest in the Asia-Pacific region and one of the largest and most developed among the Association of Southeast Asian Nations (ASEAN) countries. This study examines how to provide the most appropriate approach to enhance Thailand's pharmaceutical services to dispense medicine to end consumers. The main objective is to determine the most appropriate corporate image for Thai Pharmacy Retail Stores (PRSs) for entering the ASEAN market community. An exploratory mixed-method design characterized by qualitative and quantitative phases of data collection and analysis and the linking of data from these two separate data strands was adopted to conduct an in-depth interview with pharmacists and the owner of pharmacy retail stores as well as 405 respondents who had visited a pharmacy retail store and interacted with pharmacists during the previous year. The multiple linear regression (MLR) was applied to analyze the relative influences of perceived service quality and the cultural dimension on the corporate image. Findings reveal that the perceived service quality and cultural dimension contribute 50% towards the corporate image, and the perceived service quality had more effect than cultural dimension. This study mainly focuses on PRSs in Thailand, while the findings show other analyses concerning how to successfully create and promote an effective PRS image for ASEAN markets.

Radiosensitivity and the Occurrence of Radiation-related Cataract and Epilation

  • Tomita, Makoto;Otake, Masanori;Moon, Sung-Ho
    • Journal of the Korean Data and Information Science Society
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    • v.17 no.3
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    • pp.889-904
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    • 2006
  • Our purpose is to ascertain, if possible, whether atomic bomb survivors with cataracts and epilation were more radiosensitive than those survivors with cataracts but without epilation. A major ophthalmologic survey was conducted in Hiroshima and Nagasaki in 1963-64. At that time, 2125 individuals were examined. Among these individuals, estimated eye organ doses, based on the DS86 dosimetry system, and information on the occurrence of epilation within the first 60 days following the bombings are available on 1742. In the analysis of these data we have assumed that each individual represents a sample of one from a binomial distribution, and that the occurrence of cataracts and epilation are independent biological phenomena. We got following results. The threshold for cataract induction and its 95% confidence limits have been estimated from data on the occurrence of cataract and epilation. Among the 1742 study subjects, 40 had both cataracts and severe epilation. The estimated threshold based on these cases is 0.98 sievert(Sv), with 95% lower and upper confidence bounds of 0.72, and 1.32 Sv, respectively, and is highly statistically significant. Among the 27 cases of cataracts where severe epilation was not reported, the estimated threshold is 1.74 Sv with 95% lower and upper confidence bounds of 1.21 Sv, and "not estimable". The difference between these two estimates is not statistically significant although the effect of dose is highly significant in both instances. The potential importance of biases in the DS86 dose estimates is discussed. The difference between the threshold estimated from cataract cases with epilation and that from cases without epilation is not statistically significant at the 5% or 10% level, and thus affords no support for the notion of increased radiosensitivity.

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Impact of Negative Review Type, Brand Reputation, and Opportunity Scarcity Perception on Preferences of Fashion Products in Social Commerce (소셜커머스에서 부정적 리뷰 유형, 브랜드 명성, 기회희소성지각이 패션제품 선호도에 미치는 영향)

  • Joo, Bora;Hwang, Sunjin
    • Journal of Fashion Business
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    • v.20 no.4
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    • pp.207-225
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    • 2016
  • This study aims to analyze the impact of negative review type, brand reputation and opportunity scarcity perception, on preferences of fashion products in social commerce. For the above evaluation, we used the 2 (negative review type: objective/subjective) ${\times}2$ (brand reputation: high/low) ${\times}2$ (opportunity scarcity perception: high/low) model, designed with three mixed elements. We enrolled 260 women in their 20s and 30s, who live in Seoul and have used social commerce; a final total of 207 subjects were considered for analysis. The data were analyzed using the SPSS 18 program and reliability test, t-test and three-way ANOVA were performed. Following observations were made: First, preferences were higher when the subjects read objective negative reviews than subjective negative reviews, and when a fashion product was from a brand of high reputation than a brand of low reputation. Second, the interaction effect between negative review type and brand reputation was greater among the subjects whose opportunity scarcity perception is high, than those having low opportunity scarcity perception. Thus, we conclude that the social commerce should encourage consumers to write more objective reviews, and fashion brands should manage their reputations well. Also, social commerce can use scarcity messages aggressively to increase preferences of global fashion luxury goods, which is actively marketed in social commerce since 2015.

Growth and Photocurrent Study on the Splitting of the Valence Band for $CuInSe_2$ Single Crystal Thin Film by Hot Wall Epitaxy (Hot Walll Epitaxy (HWE)법에 의한 $CuInSe_2$ 단결정 박막 성장과 가전자대 갈라짐에 대한 광전류 연구)

  • Yun, Seok-Jin;Hong, Gwang-Jun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2004.11a
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    • pp.234-238
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    • 2004
  • A stoichiometric mixture of evaporating materials for $CuInSe_2$ single crystal thin films was prepared from horizontal electric furnace. To obtain the single crystal thin films, $CuInSe_2$ mixed crystal was deposited on thoroughly etched semi-insulating GaAs(100) substrate by the hot wall epitaxy (HWE) system. The source and substrate temperatures were $620^{\circ}C$ and $410^{\circ}C$, respectively. The crystalline structure of the single crystal thin films was investigated by the photoluminescence and double crystal X-ray diffraction (DCXD). The carrier density and mobility of $CuInSe_2$ single crystal thin films measured with Hall effect by van der Pauw method are $9.62{\times}10^{l6}\;cm^{-3}$ and $296\;cm^2/V{\cdot}s$ at 293 K, respectively. The temperature dependence of the energy band gap of the $CuInSe_2$ obtained from the absorption spectra was well described by the Varshni's relation, $E_g(T)\;=\;1.1851\;eV\;-\;(8.99{\times}10^{-4}\;eV/K)T^2/(T+153K)$. The crystal field and the spin-orbit splitting energies for the valence band of the $CuInSe_2$ have been estimated to be 0.0087 eV and 0.2329 eV at 10K, respectively, by means of the photocurrent spectra and the Hopfield quasicubic model. These results indicate that the splitting of the ${\Delta}_{so}$ definitely exists in the $\Gamma_6$ states of the valence band of the $CuInSe_2$. The three photocurrent peaks observed at 10K are ascribed to the $A_1-$, $B_1-$, and $C_1$-exciton peaks for n = 1.

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The Correlation of Serum Osteoprotegerin with Non-Traditional Cardiovascular Risk Factors and Arterial Stiffness in Patients with Pre-Dialysis Chronic Kidney Disease: Results from the KNOW-CKD Study

  • Chae, Seung Yun;Chung, WooKyung;Kim, Yeong Hoon;Oh, Yun Kyu;Lee, Joongyub;Choi, Kyu Hun;Ahn, Curie;Kim, Yong-Soo
    • Journal of Korean Medical Science
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    • v.33 no.53
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    • pp.322.1-322.14
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    • 2018
  • Background: Osteoprotegerin (OPG) plays protective roles against the development of vascular calcification (VC) which greatly contributes to the increased cardiovascular events in patients with chronic kidney disease (CKD). The present study aimed to find the non-traditional, kidney-related cardiovascular risk factors correlated to serum OPG and the effect of serum OPG on the arterial stiffness measured by brachial ankle pulse wave velocity (baPWV) in patients with the pre-dialysis CKD. Methods: We cross-sectionally analyzed the data from the patients in whom baPWV and the serum OPG were measured at the time of enrollment in a prospective pre-dialysis CKD cohort study in Korea. Results: Along with traditional cardiovascular risk factors such as age, diabetes mellitus, pulse pressure, and baPWV, non-traditional, kidney-related factors such as albuminuria, plasma level of hemoglobin, total $CO_2$ content, alkaline phosphatase, and corrected calcium were independent variables for serum OPG in multivariate linear regression. Reciprocally, the serum OPG was positively associated with baPWV in multivariate linear regression. The baPWV in the 3rd and 4th quartile groups of serum OPG were higher than that in the 1st quartile group after adjustments by age, sex and other significant factors for baPWV in linear mixed model. Conclusion: Non-traditional, kidney-related cardiovascular risk factors in addition to traditional cardiovascular risk factors were related to serum level of OPG in CKD. Serum OPG level was significantly related to baPWV. Our study suggests that kidney-related factors involved in CKD-specific pathways for VC play a role in the increased secretion of OPG into circulation in patients with CKD.

POINTWISE CROSS-SECTION-BASED ON-THE-FLY RESONANCE INTERFERENCE TREATMENT WITH INTERMEDIATE RESONANCE APPROXIMATION

  • BACHA, MEER;JOO, HAN GYU
    • Nuclear Engineering and Technology
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    • v.47 no.7
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    • pp.791-803
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    • 2015
  • The effective cross sections (XSs) in the direct whole core calculation code nTRACER are evaluated by the equivalence theory-based resonance-integral-table method using the WIMS-based library as an alternative to the subgroup method. The background XSs, as well as the Dancoff correction factors, were evaluated by the enhanced neutron-current method. A method, with pointwise microscopic XSs on a union-lethargy grid, was used for the generation of resonance-interference factors (RIFs) for mixed resonant absorbers. This method was modified by the intermediate-resonance approximation by replacing the potential XSs for the non-absorbing moderator nuclides with the background XSs and neglecting the resonance-elastic scattering. The resonance-escape probability was implemented to incorporate the energy self-shielding effect in the spectrum. The XSs were improved using the proposed method as compared to the narrow resonance infinite massbased method. The RIFs were improved by 1% in $^{235}U$, 7% in $^{239}Pu$, and >2% in $^{240}Pu$. To account for thermal feedback, a new feature was incorporated with the interpolation of pre-generated RIFs at the multigroup level and the results compared with the conventional resonance-interference model. This method provided adequate results in terms of XSs and k-eff. The results were verified first by the comparison of RIFs with the exact RIFs, and then comparing the XSs with the McCARD calculations for the homogeneous configurations, with burned fuel containing a mixture of resonant nuclides at different burnups and temperatures. The RIFs and XSs for the mixture showed good agreement, which verified the accuracy of the RIF evaluation using the proposed method. The method was then verified by comparing the XSs for the virtual environment for reactor applicationbenchmark pin-cell problem, as well as the heterogeneous pin cell containing burned fuel with McCARD. The method works well for homogeneous, as well as heterogeneous configurations.