• Title/Summary/Keyword: Mixed-effect model

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A General Mixed Linear Model with Left-Censored Data

  • Ha, Il-Do
    • Communications for Statistical Applications and Methods
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    • v.15 no.6
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    • pp.969-976
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    • 2008
  • Mixed linear models have been widely used in various correlated data including multivariate survival data. In this paper we extend hierarchical-likelihood(h-likelihood) approach for mixed linear models with right censored data to that for left censored data. We also allow a general random-effect structure and propose the estimation procedure. The proposed method is illustrated using a numerical data set and is also compared with marginal likelihood method.

A Study on the Air Pollution Potential in the Central Part of Korea (中部地方 各地의 大氣汚染潛在力에 관한 硏究)

  • 李鍾範
    • Journal of Korean Society for Atmospheric Environment
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    • v.7 no.1
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    • pp.41-47
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    • 1991
  • Air pollution potentials of the 7 cities in the central part of Korea were obtained with the mean wind speed within the mixed layer and the mixed layer height calculated by the Jump Model. Seasonal variation of the afternoon mixed layer height in Seoul area shows that low in winter and high in summer. Annual mean of the morning air pollution potential was lowest in Incheon and highest in Wonju. On the other hand annual mean of the afternoon air pollution potential was lowest in Incheon and highest in Chuncheon. Relatively low air pollution potential in Incheon can be explained as high mixed layer height and the effect of sea breeze.

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Improved Algorithm for Case-Deletion Diagnostic in Mixed Linear Models

  • Lee, Jang-Teak
    • Communications for Statistical Applications and Methods
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    • v.7 no.3
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    • pp.677-686
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    • 2000
  • Outliers may occur with respect to any of the random components in mixed linear models. We develop a use of simple, inexpensive updating formulas to consider the effect of case-deletion for mixed linear models. The method described here requires inversions of an n x n matrix, where n is the number of nonempty cells. A numerical example illustrates the use of computational formulas.

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Calculation of Mixed Lubrication at Piston Ring and Cylinder Liner Interface

  • Cho, Myung-Rae;Park, Jae-Kwon;Han, Dong-Chul
    • Journal of Mechanical Science and Technology
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    • v.15 no.7
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    • pp.859-865
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    • 2001
  • This paper reports on the theoretical analysis of mixed lubrication for the piston ring. The analytical model is presented by using the average flow and asperity contact model. The cyclic variations of the nominal minimum oil film thickness are obtained by numerical iterative method. The total friction is calculated by using the hydrodynamic and asperity contact theory. The effect of the roughness height, pattern, and engine speed on the nominal minimum film thickness, friction force, ad frictional power losses are investigated. As the roughness height increases, the nominal oil film thickness and total friction force increase. Also, the effect of the surface roughness on the boundary friction is dominant at low engine speed and high asperity height. The longitudinal roughness pattern shows lower mean oil film pressure and thinner oil film thickness compared to the case of the isotropic and transverse roughness patterns.

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Experimental Studies on the Hair Growth Activity of Mixed Extracts of Mylabris Phalerata Pall. and Drynariae Rhizoma in Spontaneous Alopecia Model and Normal C57BL/6N Mice (자발적인 원형탈모 생쥐(C57BL/6N)와 정상적인 생쥐에서 반모(斑毛)와 골쇄보(骨碎補) 추출 혼합물의 발모(發毛)효과에 대한 실험적 연구)

  • Lee, Moon-Won;Jo, Han-Young;Kim, Tae-Heon;Kim, Nam-Seok;Jeong, Han-Sol;Lee, Chang-Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.4
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    • pp.778-790
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    • 2008
  • This experiment investigated the effect of mixed extracts obtained from Mylabris phalerata Pall. and Drynariae Rhizoma on hair growth activity of the normal and spontaneous alopecia areata model of C57BL/6N mice for 16 days. First, we examined morphological regrowth of hair in normal and spontaneous alopecia model of C57BL/6N mice. Second, we examined immunoreactive density of vascular endothelial growth factor(VEGF), c-kit and protein kinase $C-{\alpha}(PKC-{\alpha})$ in skin of normal C57BL/6N mice by immunohistochemical methods. Third, we investigated expression of $TGF-{\beta}$, prolactin and placenta lactogen after topical application of mixed extracts of Mylabris phalerata Pall. and Drynariae Rhizoma to skin by RT-PCR. The results were as follows: Hair growth effect from middle and high concentration of mixed extracts of Mylabris phalerata Pall. and Drynariae Rhizoma was observed in 80% of normal mice in whose hair had been clipped in 15th days. Hair growth effect of all concentrations of mixed extracts of Mylabris phalerata Pall. and Drynariae Rhizoma was observed in 100% of spontaneous alopecia model of C57BL/6N mice in 15th days. Immunoreactive density of VEGF, c-kit and $PKC-{\alpha}$ in skin of all concentrations of mixed extracts of Mylabris phalerata Pall. and Drynariae Rhizoma were strongly stained in epidermis, bulge, secondary hair germ cells and cutaneous trunci m. compare to control group in 10th day. In experimental III group, Immunoreactive density of VEGF, c-kit and $PKC-{\alpha}$ in skin were strongly stained in inner and outer root sheath of skin. The treatment of mixed extracts of Mylabris phalerata Pall. and Drynariae Rhizoma increased the expression of $TGF-{\beta}$, placenta lactogen and prolactin in the skin of normal C57BL/6N mice compared to control group. These experiments suggest that mixed extracts of Mylabris phalerata Pall. and Drynariae Rhizoma may stimulate the topical hair growth activity and it can be useful for treatment of alopecia areata.

Formulating the Landscape Preference Model Using a Mixed Conditional Logit (조건부 로짓함수를 이용한 경관선호 모델: 지리산 국립공원 방문자를 대상으로)

  • Lee, Deokjae
    • Journal of Korean Society of Forest Science
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    • v.95 no.6
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    • pp.768-777
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    • 2006
  • The purpose of this study lies in formulating the landscape preference model using a conditional logit that involves the effect of visual elements as well as landscape itself on landscape preferences. To measure landscape preferences, a photo-questionnaire composed of paired photographs of the Cairngorms National Park of Scotland and the Jirisan National Park of Korea was distributed to visitors to the Jirisan National Park of Korea. Visual elements of landscape quantitatively measured by photogrammetry were reduced to orthogonal principal components that were subsequently used as explanatory variables in a conditional logit. As a result, the mixed conditional logit including the effect of landscape itself satisfied the Independence of Irrelevant Alternatives (IIA) property and showed reliable goodness of fit (${\rho}^2=0.25$). It was concluded that the mixed conditional logit including the effect of landscape itself was appropriate for landscape preference model rather than usual conditional logit excluding the effect.

Testing Independence in Contingency Tables with Clustered Data (집락자료의 분할표에서 독립성검정)

  • 정광모;이현영
    • The Korean Journal of Applied Statistics
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    • v.17 no.2
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    • pp.337-346
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    • 2004
  • The Pearson chi-square goodness-of-fit test and the likelihood ratio tests are usually used for testing independence in two-way contingency tables under random sampling. But both of these tests may provide false results for the contingency table with clustered observations. In this case we consider the generalized linear mixed model which includes random effects of clustering in addition to the fixed effects of covariates. Both the heterogeneity between clusters and the dependency within a cluster can be explained via generalized linear mixed model. In this paper we introduce several types of generalized linear mixed model for testing independence in contingency tables with clustered observations. We also discuss the fitting of these models through a real dataset.

Maximum likelihood estimation of Logistic random effects model (로지스틱 임의선형 혼합모형의 최대우도 추정법)

  • Kim, Minah;Kyung, Minjung
    • The Korean Journal of Applied Statistics
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    • v.30 no.6
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    • pp.957-981
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    • 2017
  • A generalized linear mixed model is an extension of a generalized linear model that allows random effect as well as provides flexibility in developing a suitable model when observations are correlated or when there are other underlying phenomena that contribute to resulting variability. We describe maximum likelihood estimation methods for logistic regression models that include random effects - the Laplace approximation, Gauss-Hermite quadrature, adaptive Gauss-Hermite quadrature, and pseudo-likelihood. Applications are provided with social science problems by analyzing the effect of mental health and life satisfaction on volunteer activities from Korean welfare panel data; in addition, we observe that the inclusion of random effects in the model leads to improved analyses with more reasonable inferences.

Temperature Variations in the Mixed Layer with the Passage of Typhoons Using One-Dimensional Numerical Model (1차원 모델상에서 태풍통과시의 혼합층 수온 변화)

  • Hong, Chul-Hoon;Masuda, Akira
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.51 no.1
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    • pp.107-112
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    • 2018
  • One-dimensional numerical model is implemented to investigate temperature variations in the mixed layer depth (MLD) with the passage of typhoons. In the model, we assume a non-divergent, infinite ocean and consider wind effects only, excluding isostatic effects (inverse barometric effects) and upwelling with vertical movement of the water column. Numerical experiments investigate the effects of typhoon tracks on temperature variations, including their dependence on vertical resolutions in the MLD and these results are compared with those in a three-dimensional primitive equation model (POM). The model reproduces features of the observed temperature variations in the MLD fairly well, and implies that wind effects, rather than isostatic effects, play a predominant role in temporal and spatial temperature variations in the MLD. After the passage of typhoons, however, the model does not reproduce well the temperature variations observed in the MLD, because a limitation of the model is its inability to reproduce events such as cyclonic eddy formation (Hong et al., 2011; Masuda and Hong, 2011). The model also shows well the so called 'rightward bias' (Price, 1981) of sea surface cooling which is the most predominant in the right hand side of typhoon's track.

Analysis of shallow footings rested on tensionless foundations using a mixed finite element model

  • Lezgy-Nazargah, M.;Mamazizi, A.;Khosravi, H.
    • Structural Engineering and Mechanics
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    • v.81 no.3
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    • pp.379-394
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    • 2022
  • Shallow footings usually belonged to the category of thick plate structures. For accurate analysis of thick plates, the contribution of out-of-plane components of the stress tensor should be considered in the formulation. Most of the available shallow footing models are based on the classical plate theories, which usually neglect the effects of the out-of-plane stresses. In this study, a mixed-field plate finite element model (FEM) is developed for the analysis of shallow footings rested on soil foundations. In addition to displacement field variables, the out-of-plane components of the stress tensor are also assumed as a priori unknown variables. For modeling the interaction effect of the soil under and outside of the shallow footings, the modified Vlasov theory is used. The tensionless nature of the supporting soil foundation is taken into account by adopting an incremental, iterative procedure. The equality requirement of displacements at the interface between the shallow footing and soil is fulfilled using the penalty approach. For validation of the present mixed FEM, the obtained results are compared with the results of 3D FEM and previous results published in the literature. The comparisons show the present mixed FEM is an efficient and accurate tool for solving the problems of shallow footings rested on subsoil.