• Title/Summary/Keyword: Mixed distribution

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The Local Myocardial Perfusion Rates of Right Atrial Cardioplegia in Hearts with Coronary Arterial Obstruction (관상동맥 협착을 동반한 심장에서 심근보호액 우심방 관류법의 심근 국소관류량)

  • Lee, Jae-Won;Seo, Gyeong-Pil
    • Journal of Chest Surgery
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    • v.25 no.1
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    • pp.1-16
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    • 1992
  • The quantitatively measured local myocardial perfusion rates with microspheres are used as an objective indicator of even distribution of cardioplegic solution, and the efficacy of the retrograde right atrial route of cardioplegia is evaluated in hearts with various levels of coronary arterial obstruction. After initial antegrade cardioplegia under the median sternotomy and aortic cannulation, 60 hearts from anesthetized New Zealand white rabbits are divided in random order as normal group [ligated left main coronary artery ; MA, MR] and diagonal group [ligated proximal diagonal artery ; LA, LR]. Half of each group [N=10] are perfused with antegrade cardioplegia[A] under the pressure of 100 cmH2O and the other half with retrograde right atrial route[R] under the pressure of 60 cmH2O[St. Thomas cardioplegic solution mixed with measured amount of microspheres]. The myocardium is subdivided into segments as A[atria], RV[right ventricle]. S[septum], LV[normally perfused left ventricular free wall], ROI[ischemic myocardium of left ventricular free wall]. LV and RQI are further divided into N[subendocardium] and P[subepicardium]. The resulting local myocardial perfusion rates and N /P of each group are compared with Wilcoxon rank sum test. The weight of the hearts is 5.94$\pm$0.66g, and there are no statistically significant dif-ferences[p>0.05, ANOVA] between six compared group. The mean flow rate[F: ml /g / min] of MR group is comparable with MA group[p>0.05], but in N and L group, there are significantly depressed F with right atrial route of cardioplegia, which means elevated perfusion resistance with this route. In spite of no significant differences in delivered doses of microsphere[DEL] between compared groups[p>0.05, ANOVA], there are significantly depressed REC and NF in hearts with right atrial cardioplegia which suggests increased requirement of cardioplegic solution with this route. The interventricular septum shows poor perfusion with right atrial route of cardioplegia without obstruction of supplying coronary arteries. But, with obstruction of coronary artery supplying septum as in M group, the flow rate is superior with right atrial route of infusion. The left ventricular free wall perfusion rates of every RQI with R route are superior to that of A route[p<0.05]. But, in LV segments, there are unfavorable effects of right atrial cardioplegia in L group, although the subendocardial perfusion is well maintained in N group. The LV free wall of left main group shows depressed perfusion rates with antegrade route as compared with RQI segments of diagonal group. But, by contraries, there are increased perfusion rates and superior N /P ratio with retrograde right atrial route. It implies more effective perfusion with right atrial route of cardioplegia in more proximal coronary arterial obstruction[i.e., M group as compared with L group]. As a conclusion, all region of ischemia have superior perfusion rates with right atrial car-dioplegia as compared with antegrade route, and especially excellent results can be obtained in hearts with more proximal obstruction of coronary arteries which would otherwise result in more severe ischemic damage. But, the depressed perfusion rates of the segments with normal coronary artery in hearts with coronary arterial obstruction may be a problem of concern with right atrial cardioplegia and needs solution.

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Analysis of Geochemical Characteristics in the Intertidal Zone of Hyung-Do, Shi-Hwa Lake (시화호 형도 갯벌의 지화학적 특성 분석)

  • Lee, Jun-Ho;Jeong, Kap-Sik;Woo, Han-Jun;Cho, Jin-Hyung;Lee, Seung-Yong;Jang, Seok
    • Journal of Wetlands Research
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    • v.13 no.2
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    • pp.243-263
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    • 2011
  • In order to understand the sedimentary environment of the southern intertidal zone of Shihwa Lake, west coast of Gyeonggi-do, 10 surface and 2 core sediment samples were analysed for grain size, water content, AVS (Acid Volatile Sulfide), TOC (Total Organic Carbon), concentrations of metals (Al, Fe, Mn, Cu, As, Pb, Zn, Ni, Cd, and Cr). The surface sediments are generally poorly sorted (0.60~2.31 ${\phi}$) sandy Silt, slightly gravelly muddy Sand, silty Sand, Sand with mean grain size of 2.95 to 6.00 ${\phi}$. The sediments contain Al (1.54%), Fe (1.75%), Cu (9.1ppm), As (1.1ppm), Pb (18.8 ppm), Ni (11.0 ppm), Cd (0.02 ppm), and Cr (30.1 ppm) on the average. Heavy metals are concentrated less than ERL (Effect Range-Low), verified by NOAA (National Oceanic and Atmospheric Administration). In the core sediments, they are also less than the ERL. Based on the uniform vertical distribution of excess radioactivity of $^{210}Pb$, the core sediments seen to have been actively mixed biologically or rapidly deposited after the construction of Shi-Hwa Seawall. The 'enrichment factor' of metals, normalized to Al, shows that the upper sediments of 35 cm in depth are more polluted. infect was significant in 2 core sediment samples in 35 cm below layer.

Kinetic Study on Preparation of Iron Fine Powders by Hydrogen Reduction of Ferous Chloride Vapor (염화물의 기상환원반응에 의한 미립질 철분말의 생성속도에 관한 연구)

  • Lee, Hwa-Yeong;Kim, Seong-Gyu
    • Korean Journal of Materials Research
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    • v.10 no.6
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    • pp.385-391
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    • 2000
  • A kinetic study on the preparation of iron powder by hydrogen reduction of ferrous chloride vapor has been carried out both experimentally and theoretically. For the preparation of iron powder, ferrous chloride was vaporized and transported to a reaction zone by Ar gas used as carrier. Ferrous chloride vapor and hydrogen were mixed and subject to a reduction reaction at high temperature to produce iron powder and HCI gas. Iron powder was collected with organic solvent at the end of reaction zone and HCI gas was also absorbed in a caustic soda solution to determine the conversion ratio of ferrous chloride. For the development of rate equations, a 1st-order reaction and equilibration of ferrous chloride vapor with Ar gas were assumed. According to the results, the rate constant, k could be expressed as $k=7,879exp(-53,840/RT)\textrm{dm}^3/mole.sec$ and the activation energy was found to be 53.84kJ/mole. From TEM observation, the particle size distribution of iron powder produced was found to be in the range of $0.1~1.0{\mu\textrm{m}}$ which was not significantly influenced by reaction temperature or gas flow rates.

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Distribution of Chromium in Radish and Soil by Successive Leather Processing Sludge Treatment (피혁폐기물 연용에 따른 토양 및 식물체내 크롬분포)

  • Kwon, Soon-Ik;Jung, Kwang-Yong;Jung, Goo-Bok;Park, Baeg-Gyoon
    • Korean Journal of Environmental Agriculture
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    • v.19 no.1
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    • pp.20-25
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    • 2000
  • Leather processing sludge were amended in sandy loam soil successively to investigate effects on soil properties and radish crop. Total nitrogen concentration of the sludge was $60\;g\;kg^{-1}$, and chromium was $9,048\;mg\;kg^{-1}$. Sludges were treated twice each year for 4 year, and the soils were mixed with sludge to give mixtures equivalent to sludge application rates of 12.5, 25 and $50\;Mg\;ha^{-1}\;yr^{-1}$ in dry matter. Chemical fertilizers $(N-P-K\;:\;280-59-154\;kg\;ha^{-1})$ used as a control. All treated soils were croped to altari and kimjang radish in spring and fall respectively. Organic matter and Cr content in soils were increased with input rate and years of successive application of leather processing sludge, while phosphorous and potassium contents were decreased. Yields of the first harvested altari grown in sludge treated pots were less than control. In the other hand, yields of the first kimjang radish were more than control in proportion with sludge input rates until third year fall. But in fourth year, all sludge treated pot was much less than control in radish yield. Chromium contents of radish in treated soil increased and Cr contents in leaves of radish were higher than roots. Leather processing sludge was considered a potential hazardous resource to soil and crops when it use continuously, because it has high Cr concentration.

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Floristic study of Mt. Unbongsan in the basalt areas, Korea (현무암지대 운봉산의 관속식물상)

  • Kim, Jung-Hyun;Park, Hwan-Joon;Lee, Kyeong-Ui;Kim, Jin-Seok
    • Korean Journal of Environmental Biology
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    • v.38 no.3
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    • pp.371-387
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    • 2020
  • This study was conducted to investigate the flora of Mt. Unbongsan in the basalt areas of Korea. From the results of eight field surveys undertaken from March to October 2017, we identified 404 total taxa, representing 364 species, seven subspecies, and 33 varieties, which were placed in 256 genera and 91 families. The plant formation of Mt. Unbongsan is a deciduous broad-leaved and conifer mixed forest, which is common in the middle part of the Korean peninsula. Most of the mountain is covered by a young secondary forest, which is mainly composed of Quercus monglica and Pinus densiflora. Out of these 404 taxa, 193 were the first records for the region, six were endemic to Korea, three were listed on the Korean Red List of threatened species, 34 were floristic target species, and 40 were invasive alien species. The naturalized index(NI) percentage was 9.9%. Mt. Unbongsan has plant diversity, which was associated with the geomorphological landscapes. We considered that the composition and distribution of the species were affected by different environmental factors according to the presence of granite, taluses, block streams, drying ridges, valleys, puddles, wetlands, and streams.

Mutual Separation of Am and Eu by Solvent Extraction with di-(2-ethylhexyl)phosphoric acid Containing Zirconium(III) (Zr을 함유한 di-(2-ethylhexyl)phosphoric acid에 의한 Am과 Eu의 상호분리(III))

  • Yang, Han-Beom;Lee, Eil-Hee;Lim, Jae-Gwan;Kim, Jong-Gu;Kim, Jung-Suk;Yoo, Jae-Hyung
    • Applied Chemistry for Engineering
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    • v.8 no.6
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    • pp.1006-1013
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    • 1997
  • This study was carried out to elucidate the chemical characteristics of mutual separation for Am and Eu, which were selected as a stand-in from minor actinide and rare earth elements, by solvent extraction with di-(2-ethylhexyl)phosphoric acid containing zirconium at batch system. As results, 92.3% of Am and 99.1% of Eu were coextracted with 1M DEHPA/n-dodecane containing zirconium (Zr $concentration=8.7g/{\ell}$) at 0.5M $HNO_3$ in the extraction step. The extraction yields of Am and Eu were proportionally increased with the concentration of Zr in Zr salt of 1M DEHPA/n-dodecane having the synergistic effect. In the lst stripping step for the selective separation of Am, 38.1% of Am and 3% of Eu were stripped with the mixed solution of 0.05M DTPA and 1M lactic acid adjusted pH of 3.0. At that time, the separation factor calculated from the distribution coefficients of Am and Eu was 14.2. In the 2nd Stipping step to remove the Eu remained the organic phase after the lst stripping step, 94.4% 0f Eu was stripped into aqueous phase with 6M $HNO_3$.

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Phylogenetic Analysis of Korean Black Cattle Based on the Mitochondrial Cytochrome b Gene (mtDNA cytochrome b에 기초한 한국흑우의 계통유전학적 분석)

  • Kim, Jae-Hwan;Byun, Mi Jung;Kim, Myung-Jick;Suh, Sang Won;Kim, Young-Sin;Ko, Yeoung-Gyu;Kim, Sung Woo;Jung, Kyoung-Sub;Kim, Dong-Hun;Choi, Seong-Bok
    • Journal of Life Science
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    • v.23 no.1
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    • pp.24-30
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    • 2013
  • The purpose of this study was to identify genetic polymorphisms of the mitochondrial cytochrome b (mtDNA cyt b) gene in Korean black (KB) cattle breed and to analyze the genetic relationship between the KB and other breeds. We determined the complete sequence of the mtDNA cyt b gene in 38 KB cattle. We also analyzed their genetic diversity, and phylogenetic analysis was performed by comparison with Korean cattle (KC, called Hanwoo) and breeds from China and Japan. A nucleotide substitution was detected in the KB cattle, and two haplotypes were defined. In the neighbor-joining (NJ) tree, the haplotypes of KB were located in Bos taurus lineage with those of KC, Japanese black (JB), Yanbian and Zaosheng breeds. However, the haplotypes of Chinese breeds, excluding Yanbian and Zaosheng, were separated into B. taurus and B. indicus lineages. In the NJ tree of breeds based on Dxy genetic distances, Chinese breeds mixed with B. taurus and B. indicus lineages were located between B. indicus and B. taurus lineages. KB was contained within B. taurus lineage and was determined to be genetically more closely related to two Chinese (Yanbian and Zaosheng) breeds than to KC and JB. The haplotype distribution and the results of the phylogenetic analysis suggest that KB and KC have genetic differences in their mtDNA cyt b gene sequences.

Effect of Type I Collagen on Hydroxyapatite and Tricalcium Phosphate Mixtures in Rat Calvarial Bony Defects

  • Kim, Jung-Hwan;Kim, Soung-Min;Kim, Ji-Hyuck;Kwon, Kwang-Jun;Park, Young-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.34 no.1
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    • pp.36-48
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    • 2008
  • To repair bone defects in the oral and maxillofacial field, bone grafts including autografts, allografts, and artificial bone are used in clinical dentistry despite several disadvantages. The purpose of this study was to evaluate new bone formation and healing in rat calvarial bone defects using hydroxyapatite (HA, $Ca_{10}[PO_4]_6[OH]_2,\;Bongros^{(R)}$, Bio@ Co., KOREA) and tricalcium phosphate (${\beta}-TCP,\;Ca_3[PO_4]_2$, Sigma-Aldrich Co., USA) mixed at various ratios. Additionally, this study evaluated the effects of type I collagen (Rat tail, BD Biosciences Co., Sweden) as a basement membrane organic matrix. A total of twenty, 8-week-old, male Sprague-Dawley rats, weighing 250-300g, were divided equally into a control group (n=2) and nine experimental groups (n=2, each). Bilateral, standardized transosseous circular calvarial defects, 5.0 mm in diameter, were created. In each experimental group, the defect was filled with HA and TCP at a ratio of 100:0, 80:20, 70:30, 60:40, 50:50, 40:60, 30:70, 20:80, and 0:100 with or without type I collagen. Rats were sacrificed 4 and 8 weeks post-operation for radiographic (standardized plain film, Kodak Co., USA), histomorphologic (H&E [Hematoxylin and Eosin], MT [Masson Trichrome]), immunohistochemical staining (for BMP-2, -4, VEGF, and vWF), and elementary analysis (Atomic absorption spectrophotometer, Perkin Elmer AAnalyst $100^{(R)}$). As the HA proportion increased, denser radiopacity was seen in most groups at 4 and 8 weeks. In general radiopacity in type I collagen groups was greater than the non-collagen groups, especially in the 100% HA group at 8 weeks. No new bone formation was seen in calvarial defects in any group at 4 weeks. Bridging bone formation from the defect margin was marked at 8 weeks in most type I collagen groups. Although immunohistochemical findings with BMP-2, -4, and VEGF were not significantly different, marked vWF immunoreactivity was present. vWF staining was especially strong in endothelial cells in newly formed bone margins in the 100:0, 80:20, and 70:30 ratio type I collagen groups at 8 weeks. The calcium compositions from the elementary analysis were not statistically significant. Many types of artificial bone have been used as bone graft materials, but most of them can only be applied as an inorganic material. This study confirmed improved bony regeneration by adding organic type I collagen to inorganic HA and TCP mixtures. Therefore, these new artificial bone graft materials, which are under strict storage and distribution systems, will be suggested to be available to clinical dentistry demands.

A THEMATIC SURVEY ON THE REPORTS PUBLISHED IN THE JOURNAL OF THE KOREAN ACADEMY OF PEDIATRIC DENTISTRY (역대 대한소아치과학회지 게재논문의 분야별 분포에 대한 조사)

  • Kim, Jae-Moon;Jeong, Tae-Sung;Kim, Shin
    • Journal of the korean academy of Pediatric Dentistry
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    • v.29 no.2
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    • pp.270-277
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    • 2002
  • Since founded in 1959, it's well known that the KAPD has pioneered in the researches and clinical aspects of pediatric dentistry in Korea. It's official journal, the Journal of the KAPD, was first published in 1974 and has pressed total 956 articles up to now(March, 2001). In this study, all the articles pressed in this journal have been surveyed, focussing in their main theme, their chronological and thematic distribution. The thematic classification was made with the reference of the previous studies and renowned textbooks in pediatric dentistry. And we obtained the results as follows: 1. The researches on dental materials and dental equipments have shown continuous increase throughout the period. 2. The researches on dental caries, caries prevention and systemic disorders have occupied relatively high proportion consistently. 3. The researches on malocclusions and cysts/minor surgery have shown increasing tendency in the second period, but are decreasing in the third period. 4. The researches on craniofacial growth/development, tooth development/eruption, developmental disorders of teeth, management of eruption space have shown decreasing tendency. 5. The researches on behavioral research, oral habits, occlusion of primary-mixed dentition have shown very low proportion, reaching no more than 1% throughout the period.

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Optimal Design and Economic Evaluation of Energy Supply System from On/Off Shore Wind Farms (육/해상 풍력기반 에너지생산 공정 최적 설계 및 경제성 평가)

  • Kim, Minsoo;Kim, Jiyong
    • Korean Chemical Engineering Research
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    • v.53 no.2
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    • pp.156-163
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    • 2015
  • This paper presents a new framework for design and economic evaluation of wind energy-based electricity supply system. We propose a network optimization (mixed-integer linear programming) model to design the underlying energy supply system. In this model we include practical constraints such as land limitations of onshore wind farms and different costs of offshore wind farms to minimize the total annual cost. Based upon the model, we also analyze the sensitivity of the total annual cost on the change of key parameters such as available land for offshore wind farms, required area of a wind turbine and the unit price of wind turbines. We illustrate the applicability of the suggested model by applying to the problem of design of a wind turbines-based electricity supply problem in Jeju. As a result of this study, we identified the major cost-drivers and the regional cost distribution of the proposed system. We also comparatively analyzed the economic performance of on/off shore wind farms in wind energy-based electricity supply system of Jeju.