• Biomolecules & Therapeutics
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• v.18 no.4
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• pp.426-432
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• 2010

The objective of the present study was to evaluate the effect of a mixed extract of three herbs, Panax Notoginseng, Rehmanniae Radix and Acanthopanacis cortex (AIF), for the treatment of horses with experimentally induced osteoarthritis. Twelve healthy male horses were included in this study. Horses were assigned to one of two groups: the AIF group (n=6) or the control group (n=6). Osteoarthritis was induced in all horses by intraarticular injection of sodium monoiodoacetate (0.12 mg/kg). Horses in the AIF group received 3 g of AIF with food daily, and those in the control group received food only. Treatment began on the day of intraarticular injection. Clinical and radiographic evaluations were performed every 2 weeks. At week 12, horses were euthanatized, and postmortem gross pathologic and histologic examinations of the middle carpal joint were performed. There were no significant differences in clinical values between the two groups. Radiographic evaluation revealed that the percentages of narrowness of joint space width in the control group were significantly higher than those in the AIF group (p<0.02). On gross pathologic examination, the mean total dimensions of articular cartilage erosions and fibrillations in the control group ($101.5{\pm}41.5mm^2$) were significantly wider than those in the AIF group ($29.3{\pm}39.7mm^2$; p<0.01). On histopathologic evaluation, significantly higher grades of staining intensity and lower empty lacunae (EL) ratios were found in the AIF group (p<0.03). The present study revealed that AIF had significant disease modifying effects in horses with experimentally induced osteoarthritis.

• Science of Emotion and Sensibility
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• v.21 no.3
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• pp.3-16
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• 2018

Despite the substantial changes made in the product design field to adopt light as an essential design element, there has been little effort to define how customers respond emotionally to the light design of products. Therefore, it is necessary to analyze the emotional effect of light as a new design element. However, previous research focuses solely on deriving optimal lighting conditions to achieve particular emotional effects. Therefore, this paper investigates the customers' desired emotional effects of product's light design. We studied refrigerators that utilize light as the main design element of the product. We applied mixed methods by combining close-ended questions and open-ended question to efficiently derive the desired emotion. Participants were asked to choose the most favorable refrigerator image in each of the twelve image groups and indicate why they choose that image with the short-answer survey form. Approximately one thousand terms were collected, and those terms were classified into 29 groups using thesaurus relationships. The term groups were again classified into the four big emotion categories and labelled as "abstract quality," "light property," "space perception," and "visual comfort." Also, a model of the relationship between desired light style and light properties was proposed, since we observed the light properties related to three other categories. This study used mixed methods to identify the emotional value of a new design element. We suggest that the emotional categories derived and the proposed relationship model could be used to evaluate the product's light design.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.34 no.3
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• pp.319-327
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• 2016

Korea faces a wide range of problems in areas such as safety, environment, and traffic due to the rapid economic development and urbanization process. Despite the local governments’ efforts to deal with electronic civil complaints and solve urban problems, civil complaints have been on the increase year by year. In this study, we collected civil complaint data over the last six years from a small and medium-sized city, Jinju-si. In order to conduct a spatial distribution pattern analysis, we indicated the location data on the area through Geocoding after classifying the reasons for civil complaints and then extracted the location data of the civil complaint occurrence spots in order to analyze the correlation between electronic civil complaints and land use. Results demonstrated that electronic civil complaints in Jinju-si were clustered in residential, central commercial, and residential-industrial mixed-use areas—areas where land development had been completed within the city center. After analyzing the civil complaints according to the land use, results revealed that complaints about illegal parking were the highest. Regarding the analysis results of facility distribution within a 50m radius from the civil complaint areas, civil complaints occurred a lot in detached housing areas located within the commercial and residential-industrial mixed-use areas. In the case of residential areas(old downtown), civil complaints were condensed in the areas with many ordinary restaurants. This research explored civil complaints in terms of the urban space and can be expected to be effectively utilized in finding solutions to the civil complaints

• Journal of KIISE:Software and Applications
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• v.30 no.3_4
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• pp.212-218
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• 2003

State invariant is a property that holds in every reachable state. It can be used not only in understanding and analyzing complex software systems, but it can also be used for system verifications such as checking safety, liveness, and consistency. For these reasons, there are many vital researches for deriving state invariant from finite state machine models. In previous works every reachable state is to be considered to generate state invariant. Thus it is likely to be too complex for the user to understand. This paper seeks to answer the question `how to simplify state invariant\ulcorner`. Since the complexity of state invariant is strongly dependent upon the size of states to be considered, so the smaller the set of states to be considered is, the shorter the length of state invariant is. For doing so, we let the user focus on some interested scopes rather than a whole state space in a model. Computation Tree Logic(CTL) is used to specify scopes in which he/she is interested. Given a scope in CTL, mixed reachability analysis is used to find out a set of states inside it. Obviously, a set of states calculated in this way is a subset of every reachable state. Therefore, we give a weaker, but comprehensible, state invariant.

• The korean journal of orthodontics
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• v.39 no.2
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• pp.112-119
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• 2009

Objective: To develop a mixed dentition analysis method in consideration of the normal variation of tooth sizes. Methods: According to the tooth-size of the maxillary central incisor, maxillary 1st molar, mandibular central incisor, mandibular lateral incisor, and mandibular 1st molar, 307 normal occlusion subjects were clustered into the smaller and larger tooth-size groups. Multiple regression analyses were then performed to predict the sizes of the canine and premolars for the 2 groups and both genders separately. For a cross validation dataset, 504 malocclusion patients were assigned into the 2 groups. Then multiple regression equations were applied. Results: Our results show that the maximum errors of the predicted space for the canine, 1st and 2nd premolars were 0.71 and 0.82 mm residual standard deviation for the normal occlusion and malocclusion groups, respectively. For malocclusion patients, the prediction errors did not imply a statistically significant difference depending on the types of malocclusion nor the types of tooth-size groups. The frequency of prediction error more than 1 mm and 2 mm were 17.3% and 1.8%, respectively. The overall prediction accuracy was dramatically improved in this study compared to that of previous studies. Conclusions: The computer aided calculation method used in this study appeared to be more efficient.

• Journal of Digital Convergence
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• v.11 no.4
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• pp.303-309
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• 2013

TRAINER for Kids ($T4K^{TM}$, Myofunctional. Research Co, Australia) is a prefabricated myofunctional orthodontic appliance recommended to ClassII division1 malocclusion patients who have bad oral habits such as mouth breathing, tongue thrusting, inappropriate tongue position, thumb sucking and so on. Trainer has a soft texture and a small volume so that those advantages lead to an increase in the agreement rate of young patients of its use. This presentation is to analyze clinical efficacy of Trainer. The analysis is based on a result of regular follow-up on Class II division1 malocclusion patients who has been completely treated by Trainer in the Sanbon Dental Hospital of Wonkwang university. This case report is to present the satisfactory results gained by using Trainer on Class II patients. First, Trainer was applied in Class II malocclusion patients of mixed dentition with expected space insufficient to gain facial improvement. Second, excessive overjet, overbite were improved. Third, main effects are regarded to have been achieved by development of lingual slant of upper jaw, labial slant of lower jaw, and lower part of jaw bone.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6041-6046
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• 2014

Objective: Liposarcoma (LPS) is the most common soft tissue sarcoma and accounts for approximately 20% of all mesenchymal malignancies, often occurring in deep soft tissue of retroperitoneal space. Accurate preoperative diagnosis is therefore necessary. We explored whether computed tomography (CT) could be used to differentiate between the various types of retroperitoneal liposarcoma (RPLS). Method: Forty-seven cases of RPLS, diagnosed surgically and histologically, were analyzed retrospectively. CT features were correlated with postoperative pathological appearance. Results: The study radiologist identified 29, 11, 2, 2 and 3 RPLS as atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL), dedifferentiated liposarcoma (DDL), myxoid/round cell liposarcoma (ML/RCL), pleomorphic liposarcoma (PL) and mixed-type liposarcoma. Analysis of CT scans revealed the following typical findings of the different subtypes of RPLS: ALT/WDL was mainly visible as a well-delineated fatty hypodense tumor with uniform density and integrity margin; DDL was marked by the combination of focal nodular density and hypervascularity. ML/RCL, PL and mixed liposarcoma showed malignant biological behaviour and CT findings need further studies. Conclusions: CT scanning can reveal important details including internal components, margins and surrounding tissues. Based on CT findings, tumor type can be roughly evaluated and biopsy location and therapeutic scheme guided.

• Tunnel and Underground Space
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• v.31 no.6
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• pp.469-479
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• 2021

As a material for preventing spalling of concrete, the effectiveness of PP fiber has already been confirmed. However, it is necessary to consider the maximum temperature that occurs during a fire, and to solve the mixing problem and the strength reduction problem that occur depending on the mixing amount. In this study, the fire resistance performance of tunnel segment linings according to the PP fiber content and air volume under the RABT fire scenario was investigated. As a result, no spalling or cross-sectional loss occurred in all test specimens, and when the PP fiber content was small, the maximum temperature was relatively high and the maximum temperature arrival time was also fast. On the other hand, no trend was found for the maximum temperature and arrival time according to the difference in air volume. In the internal temperature distribution results for the PP fiber mixing amount of 0.75, 1.0, 1.5, and 2.0 kg/m³, the results of 0.75 and 1.0 kg/m³ showed similar temperature distribution, and the results of 1.5 and 2.0 kg/m³ were similar. It was confirmed that the internal temperature distribution tends to decrease at the same depth when the amount of PP fiber mixed is large, and it was confirmed that a remarkable difference occurred from the results of 1.0 kg/m³ and 1.5 kg/m³ of PP fiber mixed amounts.

• International Journal of Computer Science & Network Security
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• v.24 no.4
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• pp.127-134
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• 2024

The article highlights the problems of the digitalization of the educational process, which affect the pedagogical cluster and are of a psychological nature. The authors investigate the transformational changes in education in general and the individual beliefs of each subject of the educational process, caused by both the change in the format of learning (distance, mixed), and the use of new technologies (digital, communication). The purpose of the article is to identify the strategic trend of the educational process, which is a synergistic combination of pedagogical methodology and psychological practice and avoiding dialectical opposition of these components of the educational space. At the same time, it should be noted that the introduction of digital technologies in the educational process allows for short-term difficulties, which is a usual phenomenon for innovations in the educational sphere. Consequently, there is a need to differentiate the fundamental problems and temporary shortcomings that are inherent in the new format of learning (pedagogical features). Based on the awareness of this classification, it is necessary to develop psychological techniques that will prevent a negative reaction to the new models of learning and contribute to a painless moral and spiritual adaptation to the realities of the present (psychological characteristics). The methods used in the study are divided into two main groups: general-scientific, which investigates the pedagogical component (synergetic, analysis, structural and typological methods), and general-scientific, which are characterized by psychological direction (dialectics, observation, and comparative analysis). With the help of methods disclosed psychological and pedagogical features of the process of digitalization of education in a mixed learning environment. The result of the study is to develop and carry out methodological constants that will contribute to the synergy for the new pedagogical components (digital technology) and the psychological disposition to their proper use (awareness of the effectiveness of new technologies). So, the digitalization of education has demonstrated its relevance and effectiveness in the pedagogical dimension in the organization of blended and distance learning under the constraints of the COVID-19 pandemic. The task of the psychological cluster is to substantiate the positive aspects of the digitalization of the educational process.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.26 no.6
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• pp.51-65
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• 2023

The Jeongmaeks are Korea's unique forest space recognition system that diverged from the Baekdudaegan. The Jeongmaeks are easily exposed to pressure because it is adjacent to the living area. Among them, Nakdong-Jeongmaek has high biodiversity, but damage is accelerating. According to the Convention on Biological Diversity (CBD) in 2022, the target is to expand the area of terrestrial and marine protected areas to 30% of national territory by 2030. As of September 2023, the area of terrestrial protected areas in South Korea is only 16.97% of the country's territory. This is due in part to the high proportion of private forests in the region, which makes it difficult to establish protected areas. Therefore, there is a need to establish Other Effective Area-based Conservation Measure (OECMs), which pursue complex and effective conservation that considers multiple values, as an alternative to protected areas. This study aims to identify areas suitable for OECM and to provide opinions on the establishment of appropriate management plans for each value using SOM and InVEST Habitat Quality model. This study evaluated the habitat quality of 206 villages located within 1km of the Nakdong-Jeongmaek and compared the characteristics of villages classified by SOM. As a result, the habitat quality was 0.867 for Tourism village (ClusterIV), 0.838 for Conservation village (ClusterVI), 0.835 for Mixed village (ClusterI), 0.796 for Production (ClusterV), 0.731 for Rural village (ClusterIII) and 0.625 for Urban village (ClusterII). When the distribution was identified through statistical analysis, the Kruskal-Wallis test showed that the distributions were not identical, with a p-value of 1.53e-08. Dunn's test showed a difference between Tourism, Conservation and Rural, Urban village. However, Mixed village was overestimated due to the lack of villages and the small area included in the study area. Moreover, Conservation village was somewhat under-evaluated in the analysis due to the use of a single weight for protected areas. It is necessary to perform additional reinforcement of the value evaluation of Jeongmaeks by conducting Forest Resource Survey and the National Natural Environment Survey. Therefore, we believe that sufficient validity for the establishment of OECMs in the Nakdong-Jeongmaek can be provided by addressing these limitations and conducting additional research.