• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1062-1062
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• 2001

The concept of “precision agriculture” or “site-specific farming” is usually confined to the fields of soil science, crop science and agronomy. However, because plants grow in soil, animals eat plants, and humans eat animal products, it could be argued (perhaps with some poetic licence) that the fields of feed quality, animal nutrition and animal production should also be considered in this context. NIR spectroscopy has proved over the last 20 years that it can provide a firm foundation for quality measurement across all of these fields, and with the continuing developments in instrumentation, computer capacity and software, is now a major cog in the wheel of precision agriculture. There have been a few giant leaps and a lot of small steps in the impact of NIR on the animal world. These have not been confined to the amazing advances in hardware and software, although would not have occurred without them. Rapid testing of forages, grains and mixed feeds by NIR for nutritional value to livestock is now commonplace in commercial laboratories world-wide. This would never have been possible without the pioneering work done by the USDA NIR Forage Research Network in the 1980's, following the landmark paper of Norris et al. in 1976. The advent of calibration transfer between instruments, algorithms which utilize huge databases for calibration and prediction, and the ability to directly scan whole grains and fresh forages can also be considered as major steps, if not leaps. More adventurous NIR applications have emerged in animal nutrition, with emphasis on estimating the functional properties of feeds, such as in vivo digestibility, voluntary intake, protein degradability and in vitro assays to simulate starch digestion. The potential to monitor the diets of grazing animals by using faecal NIR spectra is also now being realized. NIR measurements on animal carcasses and even live animals have also been attempted, with varying degrees of success, The use of discriminant analysis in these fields is proving a useful tool. The latest giant leap is likely to be the advent of relatively low-cost, portable and ultra-fast diode array NIR instruments, which can be used “on-site” and also be fitted to forage or grain harvesters. The fodder and livestock industries are no longer satisfied with what we once thought was revolutionary: a 2-3 day laboratory turnaround for fred quality testing. This means that the instrument needs to be taken to the samples rather than vice versa. Considerable research is underway in this area, but the challenge of calibration transfer and maintenance of instrument networks of this type remains. The animal world is currently facing its biggest challenges ever; animal welfare, alleged effects of animal products on human health, environmental and economic issues are difficult enough, but the current calamities of BSE and foot and mouth disease are “the last straw” NIR will not of course solve all these problems, but is already proving useful in some of these areas and will continue to do so.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.3
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• pp.113-120
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• 2018

In this study, we proposed a monitoring system for identifying and handling faulty sensing stream data on manufacturing equipments where low-cost sensors can be safely used. Low cost sensors will lessen the cost of implementing distributed monitoring system, but suffer from sensor noises and inaccurate sensed data. Therefore, a distributed monitoring system with low cost sensors should identify faulty signal data as either of sensor fault or machine fault, and filter out faulty signals from sensing fault. To this end, we adopted a fourier transform based diagnostic approach mixed with a weighed moving averaging method, in order to identify faulty signals. We measured how effective our approach is and found out our approach can filter out one-third faulty signals from our experimental environment. In addition, we attached wireless communication modules to reduce sensor and network installation cost. To handle massive sensor data efficiently, we employed unstructured data format with NoSQL based database.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.11
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• pp.817-825
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• 2017

The AC-common bus microgrid system can overcome several weaknesses of the DC microgrid system by interconnecting the DC/AC inverters used for renewable energy with an AC network. Nevertheless, the unbalanced loads inherent in the electric power systems of island and small communities can deteriorate the performance of the AC microgrid system. This is because of the limited voltage regulation capability and mixed power flow in the voltage source inverter. In order to overcome the unbalanced load condition, this paper proposes a voltage and current control algorithm for the 4-leg inverter based on the single phase d-q control method, as well as the modeling of the voltage controller using Matlab/Simulink S/W. From the S/W simulation and experiment of the 250KW proto-type inverter, it is confirmed that the proposed algorithm is a useful tool for the design and operation of the AC microgrid system.

• IMMUNE NETWORK
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• v.5 no.4
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• pp.221-231
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• 2005

Background: Immune regulatory dendritic cells (DCs) play an important role in maintaining self-tolerance. Recent evidences demonstrate that DCs expressing indoleamine 2,3-dioxygenase (IDO), which is involved in tryptophan catabolism, play an important role in immunoregulation and tolerance and induce T cell apoptosis. This study was devised to examine the role of IDO in the oral tolerance induction in collagen-induced arthritis (CIA) mouse model. Methods: Beginning 2 weeks before immunization, CII was fed six times to DBA/1 mice and the effect on arthritis was assessed. In tolerized mice, $CD11c^+$ DCs were isolated and stimulated with CII, IFN-${\gamma}$, and LPS with or without IDO inhibitor, 1-methyl-DL-tryptophan (1-MT) and IDO expression by $CD11c^+$ DCs was analyzed using FACS and RT-PCR. The expression of IDO, MHC II, CD80, and CD86 by $CD11c^+$ DCs were examined using confocal microscopy. Regulatory effect of $CD11c^+$ DCs on Ag-specific T cell proliferative response to CII was examined by mixed lymphocyte reaction (MLR) with or without 1-MT. Results: The proportion of IDO-expressing $CD11c^+$ DCs was slightly higher in tolerized mice than in CIA mice and significantly increased after stimulation with CII, IFN-${\gamma}$, and LPS in an IDO-dependent manner. On confocal microscopic examination, the expression of IDO was higher and those of MHC II and CD86 were lower in CD11c + DCs from tolerized mice compared to those from CIA mice. On MLR, $CD11c^+$ DCs from tolerized mice inhibited T cell proliferative response to CII in an IDO-dependent manner. Conclusion: Enhanced IDO expression by $CD11c^+$ DCs from tolerized mice may contribute to the regulation of proliferative response of CII-reactive T cells and could be involved in the induction of oral tolerance to CII.

• IMMUNE NETWORK
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• v.3 no.4
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• pp.302-309
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• 2003

Background: CTLA4 (CD152), which is expressed on the surface of T cells following activation, has a much higher affinity for B7 molecules comparing to CD28, and is a negative regulator of T cell activation. In contrast to stimulating and agonistic capabilities of monoclonal antibodies specific to CTLA-4, CTLA4Ig fusion protein appears to act as CD28 antagonist and inhibits in vitro and in vivo T cell priming in variety of immunological conditions. We've set out to confirm whether inhibition of the CD28-B7 costimulatory response using a soluble form of human CTLA4Ig fusion protein would lead to persistent inhibition of alloreactive T cell activation. Methods: We have used CHO-$dhfr^-$ cell-line to produce CTLA4Ig fusion protein. After serum free culture of transfected cell line we purified this recombinant molecule by using protein A column. To confirm characterization of fusion protein, we carried out a series of Western blot, SDS-PAGE and silver staining analyses. We have also investigated the efficacy of CTLA4Ig in vitro such as mixed lymphocyte reaction (MLR) & cytotoxic T lymphocyte (CTL) response and in vivo such as experimental autoimmune encephalomyelitis (EAE), graft versus host disease (GVHD) and skin-graft whether this fusion protein could inhibit alloreactive T cell activation and lead to immunosuppression of activated T cell. Results: In vitro assay, CTLA4Ig fusion protein inhibited immune response in T cell-specific manner: 1) Human CTLA4Ig inhibited allogeneic stimulation in murine MLR; 2) CTLA4Ig prevented the specific killing activity of CTL. In vivo assay, human CTLA4Ig revealed the capacities to induce alloantigen-specific hyporesponsiveness in mouse model: 1) GVHD was efficiently blocked by dose-dependent manner; 2) Clinical score of EAE was significantly decreased compared to nomal control; 3) The time of skin-graft rejection was not different between CTLA4Ig treated and control group. Conclusion: Human CTLA4Ig suppress the T cell-mediated immune response and efficiently inhibit the EAE, GVHD in mouse model. The mechanism of T cell suppression by human CTLA4Ig fusion protein may be originated from the suppression of activity of cytotoxic T cell. Human CTLA4Ig could not suppress the rejection in mouse skin-graft, this finding suggests that other mechanism except the suppression of cytotoxic T cell may exist on the suppression of graft rejection.

• 한국HCI학회:학술대회논문집
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• 2008.02b
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• pp.47-52
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• 2008

J.E.N(Joint Enjoyment Network) is the ubiquitous UCC play contents system that provides amusements off-line by utilizing the UCC that people are able to participate in. It is also the entertainment service system that is devised to use contents that could be enjoyed through the cell phone and to make people participate in production, in cases of meeting people off-line during their pastime. The development of this system begins from pointing out the problem of the limitation of the UCC that does participate in production but the produced contents could only be watched, and the UCC only works on-line. The goal of researching this ubiquitous UCC play contents is to suggest the UCC entertainment service system that are available off-line by applying the interactive system to UCC and, by this, to obtain the positive responses about the off-line participating UCC contents. In this research, it chooses scenario and 테스크 performance as the method of deriving the participating UCC from the off-line, and it suggests the ubiquitous UCC play contents system through analyzing the behaviors in each off-line place. Moreover, by developing the prototype that could practically perform the system, it verifies the potentialities of the UCC entertainment service. The anticipation of this study is to make people participate and enjoy not only in production, but also in the contents made. This research will provide the modern people who concern about where to go and what to do with the amusements and will also present a way of new form of contents mixed with UCC and the entertainment service.

• The Journal of Korean Association of Computer Education
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• v.17 no.6
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• pp.93-102
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• 2014

A mobile office environment using mobile devices, such as tablet PC, mobile phone is gradually increased in enterprises, banking and public institutions etc which is no limitation on places. It occurs advanced and persist security threats that are required effective security management policy and technical solution to be secure. For BYOD (Bring Your Own Device) environment, technical security management solutions of network control based, MDM (Mobile Device Management), MAM (Mobile Application Management), MCM (Mobile Contents Management) were released, evolved and mixed used. In perspective of integrated security management solution, mobile security product should be selected to consider user experience and environment and correct quality evaluation model of product is needed which is provided standards and guidance on the selection criteria when it was introduced. In this paper, the most widely used MDM solution is selected to take a look at its features and it was reviewed the product attributes with related international standard ISO/IEC25010 software quality attributes. And then it was derived evaluation elements and calculated the related metrics based on the quality analysis model. For the verification of quality evaluation model, security checks list and testing procedures were established; it applied metrics and analyzed the testing result through scenario based case study.

• Journal of Korean Society of Transportation
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• v.20 no.4
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• pp.51-61
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• 2002

In this dissertation, We demonstrated the Travel Time forecasting model in the freeway of multi-section with regard of drives' attitude. Recently, the forecasted travel time that is furnished based on expected travel time data and advanced experiment isn't being able to reflect the time-lag phenomenon specially in case of long distance trip, so drivers don't believe any more forecasted travel time. And that's why the effects of ATIS(Advanced Traveler Information System) are reduced. Therefore, in this dissertation to forecast the travel time of the freeway of multi-section reflecting the time-lag phenomenon & the delay of tollgate, we used traffic volume data & TCS data that are collected by Korea Highway Cooperation. Also keep the data of mixed unusual to applicate real system. The applied model for forecasting is consisted of feed-forward structure which has three input units & two output units and the back-propagation is utilized as studying method. Furthermore, the optimal alternative was chosen through the twelve alternative ideas which is composed of the unit number of hidden-layer & repeating number which affect studying speed & forecasting capability. In order to compare the forecasting capability of developed ANN model. the algorithm which are currently used as an information source for freeway travel time. During the comparison with reference model, MSE, MARE, MAE & T-test were executed, as the result, the model which utilized the artificial neural network performed more superior forecasting capability among the comparison index. Moreover, the calculated through the particularity of data structure which was used in this experiment.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.2765-2769
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• 2013

Background: A close association between patterns identified by magnifying narrow-band imaging (M-NBI) and histological type has been described. M-NBI patterns were also recently reported to be related to the mucin phenotype; however, detials remain unclear. Materials and Methods: We investigated the cellular differentiation of gastric cancer lesions, along with their mucosal distribution observed by M-NBI. Ninety-seven depressed-type early gastric cancer lesions (74 differentiated and 23 undifferentiated adenocarcinomas) were visualized by M-NBI. Findings were divided into 4 patterns based on abnormal microvascular architecture: a chain loop pattern (CLP), a fine network pattern (FNP), a corkscrew pattern (CSP), and an unclassified pattern. Mucin phenotypes were judged as gastric (G-type), intestinal (I-type), mixed gastric and intestinal (M-type), and null (N-type) based on 4 markers (MAC5AC, MUC6, MUC2, and CD10). The relationship of each pattern of microvascular architecture with organoid differentiation indicated by cancer cell differentiation and its distribution in each histological type of early gastric cancer was investigated. Results: All CLP and FNP lesions were differentiated. The cancer cell distribution showed organoid differentiation in 84.2% (16/19) and 61.1% (22/36) of the two types of lesions, respectively, and there was a significant difference from the unclassified pattern with organoid differentiation (p<0.001). Almost all (94.7%; 18/19) CSP lesions were undifferentiated, and organoid differentiation was observed in 72.2% (13/18). There was a significant difference from the unclassified pattern with organoid differentiation (p<0.05). Conclusions: Cellular differentiation and distribution are associated with microvascular architecture observed by M-NBI.

• Journal of Adhesion and Interface
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• v.9 no.3
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• pp.7-13
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• 2008

The particulate type silicon carbide (SiC) and fiber type carbon fiber (CF) filler, of similar thermal conductivities, were mixed with polyetheretherketone (PEEK) to investigate the filler effects on the thermal diffusivity. The SiC and CF fillers had a good and uniform dispersion in PEEK matrix. Thermal diffusivities of PEEK composites were measured from ambient temperature up to $200^{\circ}C$ by laser flash method. The diffusivities were decreased as increasing temperature due to the phonon scattering between PEEK-filler and filler-filler interfaces. Thermal diffusivity of PEEK composites was increased with increasing filler content and the thermal conductivities of two-phase system were compared to the experimental results and it gave ideas on the filler dispersion, orientation, aspect ratio, and filler-filler interactions. Nielson equation gave a good prediction to the experimental results of PEEK/SiC. The easy network formation by CF was found to be substantially more effective than SiC and it gave a higher thermal diffusivities of PEEK/CF than PEEK/SiC.