• 제목/요약/키워드: Missing-step

검색결과 79건 처리시간 0.034초

Oxidation-induced conformational change of Hsp33, monitored by NMR

  • Lee, Yoo-Sup;Kim, Ji-Hoon;Seo, Min-Duk;Ryu, Kyoung-Seok;Kim, Eun-Hee;Won, Hyung-Sik
    • 한국자기공명학회논문지
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    • 제19권3호
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    • pp.99-105
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    • 2015
  • Hsp33 is a prokaryotic molecular chaperon that exerts a holdase activity upon response to an oxidative stress at raised temperature. In particular, intramolecular disulfide bond formation between the four conserved cysteines that bind a zinc ion in reduced state is known to be critically associated with the redox sensing. Here we report the backbone NMR assignment results of the half-oxidized Hsp33, where only two of the four cysteines form an intramolecular disulfide bond. Almost all of the resolved peaks could be unambiguously assigned, although the total assignments extent reached just about 50%. Majority of the missing assignments could be attributed to a significant spectral collapse, largely due to the oxidation-induced unfolding of the C-terminal redox-switch domain. These results support two previous suggestions: conformational change in the first oxidation step is localized mainly in the C-terminal zinc-binding domain, and the half-oxidized form would be still inactive. However, some additional regions appeared to be potentially changed from the reduced state, which suggest that the half-oxidized conformation would be an intermediate state that is more labile to heat and/or further oxidation.

대장의 굴곡면을 가시화하기 위한 적응형 펼친 영상 기법 (An Adaptive Unfolding Method for Visualizing Wrinkled Colon Surface)

  • 이진희;신병석
    • 한국멀티미디어학회논문지
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    • 제9권9호
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    • pp.1160-1172
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    • 2006
  • 펼친 영상 생성 기법은 대장 전체를 하나의 영상으로 보여주므로 병변을 식별하는데 효과적이다. 그러나 광선 투사법에 기반한 이전의 펼친 영상 생성 방법은 대장의 굴곡이 심한 부분이나 접힌 부분에서 숨겨진 병리구조는 제대로 표현할 수 없었다. 이 문제를 해결하기 위해, 본 논문에서는 표면 복잡도에 따라 투사되는 광선 수를 가변적으로 조정하는 방법을 제안한다. 첫 번째로 중심 경로상의 샘플점에서 대장 벽까지 이르는 거리 값이 큰 샘플점과 작은 샘플점들을 선택하여 그 점을 기준이 되는 제어점으로 결정한다. 다음으로 샘플점에서 발사된 광선이 주름진 영역 안쪽까지 도달하도록 하기 위해 제어점 사이에 있는 샘플점들을 거리 값이 큰 제어점 부근으로 이동시킨다. 마지막으로 영상을 펼쳤을 때 일어나는 왜곡 현상을 줄이기 위해 이차원 크기변환을 한다. 이 방법을 이용하면 대장 조직을 정확하게 표현할 수 있다.

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Object detection in financial reporting documents for subsequent recognition

  • Sokerin, Petr;Volkova, Alla;Kushnarev, Kirill
    • International journal of advanced smart convergence
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    • 제10권1호
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    • pp.1-11
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    • 2021
  • Document page segmentation is an important step in building a quality optical character recognition module. The study examined already existing work on the topic of page segmentation and focused on the development of a segmentation model that has greater functional significance for application in an organization, as well as broad capabilities for managing the quality of the model. The main problems of document segmentation were highlighted, which include a complex background of intersecting objects. As classes for detection, not only classic text, table and figure were selected, but also additional types, such as signature, logo and table without borders (or with partially missing borders). This made it possible to pose a non-trivial task of detecting non-standard document elements. The authors compared existing neural network architectures for object detection based on published research data. The most suitable architecture was RetinaNet. To ensure the possibility of quality control of the model, a method based on neural network modeling using the RetinaNet architecture is proposed. During the study, several models were built, the quality of which was assessed on the test sample using the Mean average Precision metric. The best result among the constructed algorithms was shown by a model that includes four neural networks: the focus of the first neural network on detecting tables and tables without borders, the second - seals and signatures, the third - pictures and logos, and the fourth - text. As a result of the analysis, it was revealed that the approach based on four neural networks showed the best results in accordance with the objectives of the study on the test sample in the context of most classes of detection. The method proposed in the article can be used to recognize other objects. A promising direction in which the analysis can be continued is the segmentation of tables; the areas of the table that differ in function will act as classes: heading, cell with a name, cell with data, empty cell.

치킨프랜차이즈 TV광고의 비인적 속성에 따른 광고효과: 최근 K치킨의 광고 효과를 중심으로 (Advertising effects of non-human attributes of chicken franchise TV advertisement: Focusing on the recent advertisement of K chicken)

  • 조희영;조경섭
    • 한국프랜차이즈경영연구
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    • 제9권1호
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    • pp.17-25
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    • 2018
  • Purpose - This study was to investigate the effect of advertising attributes on advertising attitude, brand equity, and advertising effect of TV commercials of chicken franchise brand, which is one of the most popular food service brand in recent years. Research design, data, and methodology - This study aims to see the effect of advertising attributes on advertising effectiveness and the mediating effects of advertising attitude and brand equity. A total of 200 questionaire was collected, 15 respondents were discarded due to missing information. Therefore, a total of 185 respondents were used for this study. The data were analyzed using frequency analysis, confirmatory factor analysis, correlation analysis, three-step mediation regression analysis, and path analysis with SPSS 24.0 and AMOS 24.0 statistical program. Result - The results of the study are as follows. First, the effect of brand attitude on brand attitude and brand equity, brand equity and advertising effect on brand attitude, and brand equity on advertising effect were statistically significant. As a result of the mediating effect test, it was confirmed that the attitude of the ad and the brand equity mediates partly between the ad property and the advertisement effect. Conclusions - As a result of the study, it is suggested that the informativeness and notableness affect the consumers among the advertisement attributes, so that it is necessary to be able to convey the accurate information more clearly to the consumers when composing the contents of the advertisement. In other words, in the case of the advertisement of the chicken franchise brand corporation, it will be an effective advertisement campaign if it continuously transmits the correct advertisement message to the consumers in association with the brand.

Deep learning-based anomaly detection in acceleration data of long-span cable-stayed bridges

  • Seungjun Lee;Jaebeom Lee;Minsun Kim;Sangmok Lee;Young-Joo Lee
    • Smart Structures and Systems
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    • 제33권2호
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    • pp.93-103
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    • 2024
  • Despite the rapid development of sensors, structural health monitoring (SHM) still faces challenges in monitoring due to the degradation of devices and harsh environmental loads. These challenges can lead to measurement errors, missing data, or outliers, which can affect the accuracy and reliability of SHM systems. To address this problem, this study proposes a classification method that detects anomaly patterns in sensor data. The proposed classification method involves several steps. First, data scaling is conducted to adjust the scale of the raw data, which may have different magnitudes and ranges. This step ensures that the data is on the same scale, facilitating the comparison of data across different sensors. Next, informative features in the time and frequency domains are extracted and used as input for a deep neural network model. The model can effectively detect the most probable anomaly pattern, allowing for the timely identification of potential issues. To demonstrate the effectiveness of the proposed method, it was applied to actual data obtained from a long-span cable-stayed bridge in China. The results of the study have successfully verified the proposed method's applicability to practical SHM systems for civil infrastructures. The method has the potential to significantly enhance the safety and reliability of civil infrastructures by detecting potential issues and anomalies at an early stage.

여성노인의 낙상실태 및 충격보호팬츠 개발을 위한 기초 연구 (Basic Study on the Development of Impact Protective Pants and Falls of Elderly Women)

  • 이진숙;박정현;이정란
    • 한국의류산업학회지
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    • 제16권6호
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    • pp.945-953
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    • 2014
  • This study aims to develop protective pants to relieve impact from falls and to present basic data for the development. The survey results are as follows; First, 45% of the respondents were in their 60s and 55% of them were in their over 70s and older. Also, 64% of them have fallen once for the past year and 36% of them have fallen twice or more. The older they were, the more there were those who have fallen twice or more. This indicated the older people has experienced more fall accidents again after a initial fall accident. Second, as per accident situations, the survey showed that fall accidents happened the most in the winter and in the afternoon (12-18 pm). Also, it happened on a street mostly and they were wearing sneakers or hiking boots when they got a hurt slipped in a front or side by missing their step in a walk. The injury areas are mostly knee and ankle. They had the bruises or a sprain in their knee and ankle mostly. The rate of bone fracture was 19.5%. Therefore, the protection area to falls in lower body is the knee. But hip and hip joint should be protected with knee as well because those are usually be broken when it is damaged. Third, approximately 80% of those who were hospitalized for treatment had surgery. Patients who had surgery were rather in their over 70s than in their 60s. The older they were, the more serious their fracture was. The period of hospital or outpatient treatment is more than three weeks in many cases. They responded their health got worse after falls. Aftereffects of accidents were physical discomfort, anxiety and medical costs. Falls to the old makes physical damage, psychological damage, which cause reduced physical activity and the increased cost of health care with economic losses. So it results on a negative impact on the life of the old. Fourth, elderly females were rarely aware of impact protective clothing and they have never purchased such clothing. For impact protective pants, the major consideration was suitable design for their body types. They liked casual style with front or side pockets and simple designs without any patterns or decorations. As per pants materials, they responded that they need functionality, activity and elasticity. Among the functional points, insulation of cloths are considered importantly, so the heat reservance of material in the impact protective pants should be considered carefully.

사회현안에 대한 창의적 접근 및 활용성 관점에서 융합형 미디어아트정보시각화 연구(사례분석 중심으로) (A 'Study on 'Convergent Media Art Information Visualization' from the Creative Approach toward and Usability Perspective on Social Issues(Focusing on Case Analysis))

  • 김경남
    • 한국융합학회논문지
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    • 제7권4호
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    • pp.155-162
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    • 2016
  • 예술의 소통 및 역할 확장의 문제는 예술의 중요한 담론 중 하나이다. 한동안 소수 엘리트 층 위주의 예술 향유 및 사회에서의 역할소외를 극복하고자 많은 노력들이 시도되기도 했다. 이와 같은 와중에 미디어아트는 그 형식적 특성상, 다양한 놀이콘텐츠 및 산업적 맥락 속에서 대중과 소통하고 사회 속 친근한 예술로 다양한 역할확장에 기여하였다. 본 연구에서는 한 단계 더 나아가 미디어아트가 사회 속 현안 한 문제들에도 접속하고 활용될 수 있는지 등의 가능성을 '미디어아트정보시각화'를 통해 살펴본다. 일반적인 정보시각화 영역은, 정보 전달의 명확성에만 치중되어 있다. 그래서 수많은 정보들을 직관적으로 파악하는 데에 효과적이다 하지만, 유저의 감성이 날로 증가하는 시대에 경직된 시각표현은 유저 친화적인 부분에 있어 많은 부분 보완되어야 하며, 정보 전달의 효과성에만 집중되어 개인 정보보호 등의 2차적 사회문제 발생을 보완 하여야 하는 과제를 갖고 있다. 그에 따라 본 연구에서는 일반적인 정보시각화와 비교해, 미디어아트의 예술적 특성과 융합하여 '미디어아트정보시각화'가 어떻게 창의적으로 사회 문제에 접속하고 강점으로 관여할 수 있는 지 사례 작품들의 특징을 분석한다. 그리하여 예술의 역할 확장모색 및 예술융합을 통해 사회 현안에 대한 창의적 접근 그리고 일반적인 정보시각화에서 놓치고 있는 영역을 보완, 확장된 가치를 제공할 수 있음을 고찰한다.

응급의료전달체계의 각 요인이 중증외상환자의 예후에 미치는 영향 분석 (Prognostic Factor, for Major Trauma Patients in the Emergency Medical Service System)

  • 임득호;정태녕;이창재;진수근;김의중;최성욱;김옥준
    • Journal of Trauma and Injury
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    • 제24권2호
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    • pp.89-94
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    • 2011
  • Purpose: A few studies have assessed the factors affecting the prognoses for major trauma patients and those improving the circumstances when dealing with the trauma system. In that light, we analyzed factors, such as pre-hospital factors, the time to admission, the length of stay in the emergency department (ED) and emergency operation, influencing the outcomes for trauma patients. Methods: The patients who visited our emergency department from April 1, 2009, to February 29, 2011, due to major trauma were enrolled in the study. The inclusion criterion was a revised trauma score (RTS) < 7 or injury severity score (ISS) ${\geq}$ 16. We used reviews of medical records, to analyze each step of emergency medical care with respect to patients' sex, age, visit time and visit date. Continuous variables were described as a median with an interquartile range, and we compared the variables between the survival and the mortality groups by using the Mann-Whitney U test. Fisher's exact test was used for nominal variables. Using the variables that showed statistical significance in univariate comparisons, we performed a logistic regression analysis, and we tested the model's adequacy by the using the Hosmer-Lemeshow method. Results: A total of 261 patients with major trauma satisfied either the RTS score criterion or the ISS score criterion. Excluding 12 patients with missing data, 249 patients were included in this study. The overall mortality rate was 16.9%. Time to ED arrival, time to admission, time of ED stay, RTS, ISS, and visit date being a holiday showed statistically significant differences between the survival and the mortality groups in the univariate analysis. RTS, ISS, length of ED stay, and visit date being a holiday showed statistical significance in the multivariate analysis. Conclusion: The mortality rate did not show a significant relationship with the time to ED arrival, use of 119, on time to admission. Rather, it elicited a quite significant correlation with the trauma scoring system (RTS and ISS), the time of ED stay, and the visit date being a holiday.

울릉도 온실기체 관측자료를 이용한 배경대기 평균농도 산정 (An Estimation of Mean Background Concentrations of Greenhouse Gases Observed on Ulleungdo)

  • 임윤규;문윤섭;김진석;송상근;홍지형
    • 한국지구과학회지
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    • 제33권1호
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    • pp.32-38
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    • 2012
  • 본 연구에서는 울릉도 온실기체 관측장비(CRDS)에서 관측된 $CO_2$$CH_4$ 농도를 정형화된 QA${\cdot}$QC 처리절차를 통해 온실기체 평균 배경대기 농도값으로 활용하기 위한 정확도를 향상시켰다. QA${\cdot}$QC 처리절차는 총 3단계로 구성되었다. 첫 번째는 관측자료의 시간별 평균값을 구하기 위한 물리적 한계검사, 기후범위 검사 및 1시간 측정 자료수가 50% 이하인 자료는 제외시키는 과정으로 이루어져 있다. 두 번째는 일평균자료 산출을 위한 단계검사, 앞뒤로 같은 값일 경우는 제외, 하루 중 관측횟수가 15회 이상 및 일관측 자료의 표준편차가 일표준편차 평균의 3배 이하인 자료만 허용하는 과정이다. 세 번째는 기후적 특성분석 활용을 위한 Curve-fitting methods를 이용한 FFT 적용단계이다. 이상의 QA${\cdot}$QC 절차에 의한 $CO_2$$CH_4$의 월평균농도 값을 안면도 지구대기감시센터 자료와 일본 료리 관측자료와 비교 분석한 결과 $CO_2$에 있어서는 울릉도 관측자료 누락에 의한 영향이 다소 크게 나타나 안면도 관측값이 배경대기 평균농도 값으로 유효하였고, $CH_4$는 안면도 보다 오히려 울릉도 관측값이 한반도 배경대기 평균농도 값으로 더 적절한 것으로 추정되었다.

한국 12세 아동의 Significant Caries Index (The Significant Caries Index of 12 Years Old in Korean)

  • 안은숙;한지형
    • 치위생과학회지
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    • 제13권1호
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    • pp.91-96
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    • 2013
  • 본 연구는 제4기 국민건강영양조사 자료(2007~2009)를 바탕으로 12세 아동 중 치아우식증 고위험군을 확인하고, 치아우식증 고위험군과 저위험군으로 분류하여 인구 사회과학적 특성과, 구강건강에 대한 인식 및 행태에 대한 자료를 비교 분석하여 다음과 같은 결과를 얻었다. 1. 12세 아동 중 치아우식증 저위험군의 DMFT index는 0.89, 고위험군의 SiC index는 6.04로 6배 정도 높게 나타났으며, 이는 치아우식증 비교지표인 DMFT가 정규분포하지않고 심하게 치우쳐 있다는 결과였다. 2. 성별 분석에서는 여성이 남성에 비해 치아우식증 고위험군에 포함된 확률이 높은 것으로 나타났다(p<0.01). 3. 12세 아동이 스스로 구강건강에 대해 건강하지 못하다고 생각할수록 치아우식증 고위험군에 포함될 확률이 높아지는 것을 확인할 수 있었다. 4. 칫솔질 횟수에 따라 살펴봤을 때는 칫솟질이 불규칙할 경우가 1일 3회 이상 규칙적으로 시행하는 경우보다 고위험군에 포함될 확률이 적은 것으로 나타났다(p<0.01). 이상의 연구결과를 통해 12세 아동의 치아우식증 고위험집단에 영향을 미치는 위험요인들을 파악할 수 있었다. 이러한 결과를 바탕으로 보다 효과적인 구강보건 예방전략을 수립하는 기틀을 마련할 수 있을 것으로 사료된다.