• Journal of Nutrition and Health
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• v.35 no.9
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• pp.962-969
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• 2002

This study examined the effect of calcium supplementation and exercise on bone mineral density (BMD) and general characteristics, dietary intake and biochemical measurements for 45 healthy middle-aged women (40-57 years). Subjects were divided in to 4 groups; control group (G1), exercise group (G2), calcium supplementation group (G3), and calcium supplementation with exercise group (G4). The subjects were 45.8$\pm$ 0.66 years old. BMI(kg/$m^2$) was 23.31 $\pm$ 0.63 in Gl group, 22.92 $\pm$ 0.51 in G2 group, 23.64 $\pm$ 0.61 in G3 group, 23.40 $\pm$ 0.37 in G4 group, and BMI of all groups were in normal value. Energy intake was 1332.28㎉/day, 60% of RDA, so that may be unbalance of micronutrients. Especially, calcium intake was 62.8% of RDA that was very low level. Osteocalcine was not statistically significant but calcium supplementation group (G3) be showed increase. BMD was usually decreased by Aging, but in this study was increased in the all group, except control group. It showed increase of BMD for calcium supplementation and/or exercise. Overall results indicate that calcium supplementation and/or exercise increased BMD of middle-aged women, but long-term calcium supplementation and exercise will be able to more effect.(Korean J Nutrition 35(9) : 962~969, 2002)

• Particle and aerosol research
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• v.14 no.3
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• pp.65-72
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• 2018

Core-shell structured $Fe_3O_4/graphene$ composites were synthesized by aerosol spray drying process from a colloidal mixture of graphene oxides and $Fe_3O_4$ nanoparticles. The structural and electrochemical performance of $Fe_3O_4/graphene$ were characterized by the field-emission scanning electron microscopy, X-ray diffraction, Raman spectroscopy, cyclic voltammetry, and galvanometric discharge-charge method. Core-shell structured $Fe_3O_4/GR$ composites were synthesized in different mass ratios of $Fe_3O_4$ and graphene oxide. The composite particles were around $3{\mu}m$ in size. $Fe_3O_4$ nanoparticles were encapsulated with a graphene. Morphology of the $Fe_3O_4/graphene$ composite particles changed from a spherical ball having a relatively smooth surface to a porous crumpled paper ball as the content of GO increased in the composites. The $Fe_3O_4/GR$ composite fabricated at the weight ratio of 1:4 ($Fe_3O_4:GO$) exhibited higher specific capacitance($203F\;g^{-1}$) and electrical conductivity than as-fabricated $Fe_3O_4/GR$ composite.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.157-157
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• 2017

In last study, Genome-Wide Association Studies (GWAS) was conducted for cadmium content of 295 rice varieties including 137 rice core set and 157 Korea breeding varieties collected from Kongju National University. The results showed that 9 varieties had SNP allele and amino acid substitution in exon of chromosome 1. This study was aim to understanding mechanism of cadmium uptake to confirm correlation of cadmium and other mineral nutrients (Cu, Mn, Fe) among 9 rice varieties. Nine varieties were planted on polluted soil of mine in Korea and cadmium content in root, stem, leaf and it's brown rice was analyzed by ICP-MS (Inductively Coupled Plasma Mass spectrometer, Agilent 7700E, US). Results of this study showed that mechanism for cadmium uptake and accumulation was diversity among varieties. Chin-nong and Ho-nong contained higher levels of cadmium in root, but contained relatively lower levels cadmium in brown rice than other varieties. Cheong-nam, Nam-pyeong, Gan-cheok, Suan absorbed high levels of cadmium through root and then accumulated high cadmium to brown rice. Meanwhile, Yeong-deok and Su-kwang absorbed lower cadmium in root, but high cadmium was accumulated in brown rice. Correlations between cadmium and other mineral nutrients (Cu, Mn, Fe) were analyzed by using SPSS statistics 20. The contents of iron in leaf had minus correlation (p<0.05) with cooper and cadmium in root, cadmium in brown rice. Therefore understanding of cadmium uptake mechanism among varieties will be used to basic data for further breeding and phytoremediation.

• Korean Journal of Community Nutrition
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• v.11 no.4
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• pp.534-540
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• 2006

Recent studies have shown that environmental, biochemical, nutritional or genetic factors affect bone mineral density (BMD). The purpose of the present study was to investigate the effect of vitamin D receptor (VDR) gentotype and nutritional status on BMD of elderly women living in a rural area. Three hundred thirty five elderly women over 65 years in Asan participated the study. Data for demographic and nutrient intakes were obtained by survey with a two day 24 hr recall method. BMD was measured by broadband ultrasound attenuation (BUA) using quantitative ultrasound (QUS). VDR genotypes of the subjects analyzed with Bsm I restriction enzyme were bb (92%), Bb (7%) and BB (1%). No differences were found between genotypes bb and Bb/BB in age, menopausal age, body mass index and body fat. BUA of bb genotype was higher (62.5 $\pm$ 15.6 dB/MHz) than Bb/BB genotype (56.1 $\pm$ 17.6 dB/MHz) by Student's t-tests. Correlation analyses showed strong negative correlation of BMD and age, but positive correlation with BMI, energy and calcium intake. When subgroup analyses were conducted after stratification by the median calcium intake level (412.9 mg/d), the above median calcium intake group showed significant difference in BUA by VDR genotype while the lower median calcium intake group did not show significant difference. The current study confirmed interaction of calcium intake and VDR genotype in association with BMD. Further nutritional intervention will be needed to improve calcium status of the elderly women living in rural areas.

• The Journal of Korean Physical Therapy
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• v.21 no.4
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• pp.37-42
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• 2009

Purpose: The purpose of this study was to determine the effect of physical performance on bone mineral density (BMD) in elderly women. Methods: Twenty-one elderly women participated in this study. After testing functional ambulation category (FAC), they were classified into two groups: dependent walking group, those who could not walk independently (FAC 0~2, n=11) and independent walking group those who could walk independently (FAC 3~5, n=10). Outcome measures were: general characteristics, physical performance and BMD. General characteristics included age, body mass index (BMI) and waist-hip ratio. Physical performance included the chair rise test (CRT) and the modified fall efficacy scale (MFES). BMD was represented in the osteoporosis index (OI), T-score and Z-score. BMD was evaluated in calcaneal bone, using OsteoPro. The data was analyzed using SPSS 12.0 software and the Mann-Whitney U test and the Spearman correlation. Results: Age, BMI and waist hip ratio, which all affect BMD, showed no significant differences between groups (p>0.05). But the FAC 3~5 group showed a significantly higher score for CRT, MFES and T-score, compared with the FAC 0~2 group (p<0.05). The T-score was correlated with CRT and MFES scores (p<0.05). Conclusion: There is a positive relationship between physical performance and BMD. Therefore, improved physical performance can have a beneficial effect by reducing osteoporosis in elderly women, considering a positive relationship between physical performance and BMD.

• Korean Journal of Community Nutrition
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• v.18 no.2
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• pp.177-186
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• 2013

The purpose of this study was to investigate factors associated with Bone Mineral Density (BMD) in Korean postmenopausal women. The data from 2008-2010 Korean National Health and Nutrition Examination Survey (KNHANES) were used for data analysis. Subjects were 2,701 postmenopausal women aged ${\geq}50$ years. BMDs at whole body, total femur, femoral neck, and lumbar spine were measured by Dual-energy X-ray absorptiometry (DXA). Dietary data from 24-hour dietary recall and a food frequency questionnaire containing 63 food items were used. The proportions of osteopenia at total femur, femoral neck, and lumbar spine were 37.4%, 54.5%, and 45.4%, respectively. The proportions of osteoporosis at total femur, femoral neck, and lumbar spine were 6.2%, 25.6%, and 34.3%, respectively. Age, anthropometric index including height, weight, and Body Mass Index (BMI), parathyroid hormone, and physical activity were related to BMD, but the relationships were site specific. Total femur BMD was explained by age, weight, parathyroid hormone and intakes of carbohydrate and fruits. Femoral neck BMD was related to age, weight, parathyroid hormone and intakes of riboflavin and fruits. Lumbar spine BMD was associated with age, weight, milk and dairy products, calcium intake, and exercise. These results indicated that adequate intakes of milk and dairy products, fruits, carbohydrate, calcium, riboflavin and exercise as well as weight maintenance might play an important role in maintaining optimum bone health in Korean postmenopausal women.

• Journal of the East Asian Society of Dietary Life
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• v.24 no.6
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• pp.710-722
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• 2014

This study investigated factors affecting the bone mineral density (BMD) of Korean adult men. Data on BMD and anthropometric (height, weight, body mass index, BMI, waist circumference, body fat) and biochemical(total cholesterol, vitamin D, alkaline phosphatase, ALP) measurements were obtained from the Fourth and Fifth Korea National Health and Nutrition Examination Surveys (KNHANES, 2008~2011). Overall, BMD of the subjects was decreased from year to year (T-score of 30~39 yr decreased to 0.447 (2010~2011) from 0.106(2008~2009) and in 50~59 yr decreased to 0.234 from 0.033. Age was negatively associated with BMD (T-score 0.361 of 20~29 yr group and -0.894 of ${\geq}80yr$ group in total femoral). According to increase of weight, BMI and waist circumference continuously increased BMD. High value of total cholesterol (T-score 0.157 of 201~<230 mg/dL group and 0.064 of ${\geq}230mg/dL$ group in total femoral) and alkaline phosphatase (T-score 0.337 of ${\leq}102IU/L$ group and -0.270 of ${\geq}336IU/L$ group in total femoral) were associated with lower BMD. Overall height, weight and BMI were positively associated with BMD, and ALP were negatively associated with BMD. Finding of the present study showed that bone loss may be associated with various factors such as age, weight, BMI, total cholesterol, vitamin D and ALP density and that much attention should be paid to bone health of adult men. Therefore, practical and systematic programs are required to improve the BMD of adult men as well as to maintain bone health.

• Korean Journal of Community Nutrition
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• v.19 no.4
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• pp.328-341
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• 2014

Objectives: This study was carried out to investigate bone mineral density (BMD), blood pressure, age and biochemical index and nutrient intakes, and to analyze the relationship between BMD, blood pressure, biochemical index, nutrient intakes of Korean women. Methods: The study subjects were 499 women with a age range of 30-79 years living in Seoul and Kyunggi area who participated in 2011 KNHANES. The study subjects were divided into 5 age groups : 30 years (145), 40 years (110), 50 years (102), 60 years (85) and 70 years (57), and 3 BMD groups: normal 258 (50.4%), osteopenia 163 (32.9%) and osteoporosis 78 (16.7%). Results: The average waist circumference, BMI and body fat increased with age, but fat free mass decreased with age. Average BMD and T-score was decreased from 0.84, $0.74g/cm^2$ in 30 years to 0.05, $-1.05g/cm^2$ in 70 years. The rates of osteopenia and osteoporosis increased significantly 22% in 30~40 years, 47% in 50 years and 56% in 60~70 years. Systolic blood pressure and cholesterol were significantly increased with age. The rates of hypertension was significantly increased 2.1% in 30 years, 30.4% in 50 years 89.5% in 70 years. Average nutrient intakes such as protein, calcium, iron, vitamin A and C were significantly decreased with age. There were significant negative correlations between age and calcium, systolic blood pressure, triglyceride. Conclusions: In this study, we found the risk of osteoporosis and hypertension were significantly increase with over 50 years age. Calcium and protein intake decreased with age. Therefore, in order to prevent osteoporosis and hypertension, adult women need to be educated regarding the importance of protein, calcium and other nutrients in their diet.

• Journal of Korean Medical Science
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• v.33 no.48
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• pp.311.1-311.10
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• 2018

Background: In postmenopausal women, there is rapid bone loss due to estrogen depletion. In women, reproductive factors such as age at menarche, breastfeeding, and parity are considered risk factors of osteoporosis. Many reports suggest that obesity is associated with a reduced risk of osteoporosis. This nationwide, population-based study aims to identify the association between maternal age and osteoporosis risk in postmenopausal women of different obesity classifications. Methods: We assessed data from the Korean National Health and Nutrition Examination Survey 2010-2012. The study included 1,328 postmenopausal women, after excluding women with missing data for reproductive history among 4,546 postmenopausal women in the survey. Multivariate regression was used to identify the association between childbirth age and postmenopausal bone mineral density after adjustments for confounding factors. Results: The prevalence of postmenopausal osteoporosis was 35.24% (n = 468). After dividing the subjects into obese and non-obese groups based on body mass index (BMI) and waist circumference, there were significant differences between non-osteoporosis and osteoporosis groups with regard to age at first childbirth, age at last childbirth, and parity in the BMI-based general obesity group. The prevalence of osteoporosis was highest in women older than 35 years old at last childbirth. The prevalence of osteoporosis was also greater in women with parity ${\geq}4$ compared to those with lower parity levels. Conclusion: Postmenopausal women of older age at last childbirth and higher parity were at increased risk of osteoporosis in the BMI-based non-general obesity group.

• Tunnel and Underground Space
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• v.32 no.1
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• pp.1-19
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• 2022

In this report, new standard, published by Japanese Geotechnical Society, on in-situ stress measurements by hydraulic fracturing was reviewed. In the standard, modification was made for the calculation of fracture re-opening pressure in consideration of fracture surface roughness and residual aperture. The standard also presents how much the system compliance influences the estimation of the fracture re-opening pressure and subsequent in-situ stresses. It is shown that the stiffer the rock mass is, the system compliance should be sufficiently small enough so as to obtain in-situ stress measurement with higher confidence.