• Title/Summary/Keyword: Mimicking giant cell tumor

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A Case of a Central Giant Cell Granuloma in the Right Zygomatic Bone (우측 광대뼈에 발생한 중심 거대 세포 육아종 1예)

  • Seong, Jong Yeop;Jin, Seong Min;Kim, Jae Gu;Lee, Dong Hoon
    • Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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    • v.61 no.11
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    • pp.615-618
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    • 2018
  • The central giant cell granuloma is a benign tumor seen generally in the mandible, but rarely in other cranial bones. Herein, we present a 51-year-old man with central giant cell granuloma in the right zygomatic bone. Physical and radiologic examinations of the central giant cell granuloma in the zygomatic bone showed that specific and preoperative diagnosis is usually difficult. Therefore, clinicians should consider the possibility that central giant cell granuloma may occur in the zygomatic bone mimicking other more frequently observed lesions.

Chondroblastoma of the Talus Mimicking an Aneurysmal Bone Cyst: A Case Report (동맥류성 골낭종으로 오인된 거골에 발생한 연골모세포종: 증례 보고)

  • Park, Ji Soo;Suh, Jin Soo;Choi, Jun Young
    • Journal of Korean Foot and Ankle Society
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    • v.23 no.1
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    • pp.31-34
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    • 2019
  • Chondroblastoma is a rare benign tumor that produces giant cells and cartilage matrix. The tumor occurs in people between 10 and 25 years with slightly higher incidence in males. The condition occurs in the proximal epiphysis of the tibia and humerus, distal epiphysis of the femur, but its occurrence in the talus is relatively rare, accounting for 4% of the total number of chondroblastoma cases. Chondroblastoma is often misdiagnosed as a primary aneurysmal bone cyst, giant cell tumor, chondromyxoid, and lesion of a secondary aneurysmal bone cyst by fibrous dysplasia. The most commonly used surgical method for chondroblastoma is broad curettage with bone grafting. In general, an aneurysmal bone cyst is associated with a second degree chondroblastoma, which is approximately 20%. Chondroblastoma of the talus and secondary aneurysmal bone cysts can be misdiagnosed as primary aneurysmal bone cysts. This paper reports a case of a young male patient with chondroblastoma of the talus, which was initially misdiagnosed as an aneurysmal bone cyst with involvement of the talo-navicular joint.

A case of a Spindle cell/pleomorphic lipoma in the lateral neck (측경부에 발생한 방추세포 / 다형성 지방종1예)

  • Kim, Young Yoon;Yoon, Sung Ho;Park, Jong Min;Lee, Dong Hoon
    • Korean Journal of Head & Neck Oncology
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    • v.34 no.1
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    • pp.41-43
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    • 2018
  • The Spindle cell lipoma is a slow-growing benign tumor seen generally in the shoulders, upper back, and back of the neck of male. The Pleomorphic (giant-cell) lipoma is a benign tumor of adipose tissue with atypical histological features. It is mainly seen in the same lesion as the Spindle cell lipoma. The Pleomorphic lipoma is cytogenetically similar to spindle cell lipoma with a consistent loss of chromosome 16q material. For this reason, these two entities are regarded as a similar spectrum in the adipose tumors. Herein, we present a 53-year old man with Spindle cell/pleomorphic lipoma in the lateral neck. Physical and radiologic examinations of the Spindle cell/pleomorphic lipoma in the lateral neck are not specific and preoperative diagnosis is usually difficult. Therefore, clinicians should consider the possibility that Spindle cell/pleomorphic lipoma may occur in the lateral neck mimicking the other more frequently observed lesions.

Idiopathic Hypertrophic Spinal Pachymeningitis with an Osteolytic Lesion

  • Jee, Tae Keun;Lee, Sun-Ho;Kim, Eun-Sang;Eoh, Whan
    • Journal of Korean Neurosurgical Society
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    • v.56 no.2
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    • pp.162-165
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    • 2014
  • Idiopathic hypertrophic spinal pachymeningitis (IHSP) is a chronic, progressive, inflammatory disorder characterized by marked fibrosis of the spinal dura mater with unknown etiology. According to the location of the lesion, it might induce neurologic deficits by compression of spinal cord and nerve root. A 58-year old female with a 3-year history of progressive weakness in both lower extremities was referred to our institute. Spinal computed tomography (CT) scan showed an osteolytic lesion involving base of the C6 spinous process with adjacent epidural mass. Magnetic resonance imaging (MRI) revealed an epidural mass involving dorsal aspect of cervical spinal canal from C5 to C7 level, with low signal intensity on T1 and T2 weighted images and non-enhancement on T1 weighted-enhanced images. We decided to undertake surgical exploration. At the operation field, there was yellow colored, thickened fibrous tissue over the dura mater. The lesion was removed totally, and decompression of spinal cord was achieved. Symptoms improved partially after the operation. Histopathologically, fibrotic pachymeninges with scanty inflammatory cells was revealed, which was compatible with diagnosis of idiopathic hypertrophic pachymeningitis. Six months after operation, motor power grade of both lower extremities was normal on physical examination. However, the patient still complained of mild weakness in the right lower extremity. Although the nature of IHSP is generally indolent, decompressive surgery should be considered for the patient with definite or progressive neurologic symptoms in order to prevent further deterioration. In addition, IHSP can present as an osteolytic lesion. Differential diagnosis with neoplastic disease, including giant cell tumor, is important.