• Title/Summary/Keyword: Migration tool

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An Analysis of Urban Migration and Local Government Finance (도시의 인구이동과 지방재정에 관한 연구)

  • 김헌민
    • Korea journal of population studies
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    • v.14 no.2
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    • pp.1-17
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    • 1991
  • While various fiscal measures have been used to influence regional capital inflow or industrial location, the effect of fiscal variables on labor mobility has been little understood. Understanding the relationship between the composition of local public and urban migration would enhance the city govenment's ability to pursue an appropriate population policy. In order to examine the potential for local public finance to be utilized as a policy tool in directing urban population growth, this paper analyzes the impact of local government financial structure on urban migration. In examining the data on local government finance and the changes in population of Korean cities during the last ten years, it was found that cities with high per capita expenditure in regional development have experienced high population growth rates. In this study migration equations were constructed using various fiscal variables such as the proportion of special account expenditures which are mostly spent for local development purposes, per capita regional development expenditure, degree of local financial independence and per capita net fiscal benefit, along with other explanatory variables. The results of regression analysis showed that city government's regional development expenditure variables have a positive effect on urban net migration and a negative effect on outmigration. Fiscal independence and per capita net fiscal benefit had mixed effects on in and out migration variables, implying that local tax burden does not consistently deter inmigration or induce outmigration. Based on the results of this study some important policy implications can be found regarding local government's fiscal policies. Those cities seeking to attract higher population inflow should make a greater effort in appropriating local expenditures for regional development purposes such as infrastructure, housing, and transportation. city governments should not be too concerned about high local tax burden or necessarily seek to enhance financial independence for these factors do not exert a clear influence on urban population growth or labor supply.

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Stem cell-derived exosomes for dentin-pulp complex regeneration: a mini-review

  • Dina A. Hammouda;Alaa M Mansour;Mahmoud A. Saeed;Ahmed R. Zaher;Mohammed E. Grawish
    • Restorative Dentistry and Endodontics
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    • v.48 no.2
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    • pp.20.1-20.13
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    • 2023
  • This mini-review was conducted to present an overview of the use of exosomes in regenerating the dentin-pulp complex (DPC). The PubMed and Scopus databases were searched for relevant articles published between January 1, 2013 and January 1, 2023. The findings of basic in vitro studies indicated that exosomes enhance the proliferation and migration of mesenchymal cells, as human dental pulp stem cells, via mitogen-activated protein kinases and Wingless-Int signaling pathways. In addition, they possess proangiogenic potential and contribute to neovascularization and capillary tube formation by promoting endothelial cell proliferation and migration of human umbilical vein endothelial cells. Likewise, they regulate the migration and differentiation of Schwann cells, facilitate the conversion of M1 pro-inflammatory macrophages to M2 anti-inflammatory phenotypes, and mediate immune suppression as they promote regulatory T cell conversion. Basic in vivo studies have indicated that exosomes triggered the regeneration of dentin-pulp-like tissue, and exosomes isolated under odontogenic circumstances are particularly strong inducers of tissue regeneration and stem cell differentiation. Exosomes are a promising regenerative tool for DPC in cases of small pulp exposure or for whole-pulp tissue regeneration.

A Design of Multi-Field User Interface for Simulated Breeding

  • Unemi, Tastsuo
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 1998.06a
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    • pp.489-494
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    • 1998
  • This paper describes a design of graphical user interface for a simulated breeding tool with multifield. The term field is used here as a population of visualized individuals that are candidates of selection. Multi-field interface enables the user to breed his/her favorite phenotypes by selection independently in each field, and he/she can copy arbitrary individual into another field. As known on genetic algorithms, a small population likely leads to premature convergence trapped by a local optimum, and migration among plural populations is useful to escape from local optimum. The multi-field user interface provides easy implementation of migration and wider diversity. We show the usefulness of multi-field user interface through an example of a breeding system of 2D CG images.

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Migration Activity of Chicken Gonadal Primordial Germ Cells (gPGCs) and Post-transfer Localization of LacZ-transfected gPGCs in the Embryonic Gonads

  • Jeong, D.K.;Han, J.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.9
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    • pp.1227-1231
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    • 2002
  • A powerful tool for chicken transgenesis could be established by employing a germline chimera production through primordial germ cell transplantation. This study was conducted to examine whether foreign gene-transfected gonadal primordial germ cells (gPGCs) have a migration activity into the gonad after transfer to recipient embryos. In Experiment 1, gPGCs of Korean Ogol Chicken were retrieved from 5.5-day-old embryos and subsequently transferred to the dorsal aorta of 2.5-day-old White Leghorn embryos after being labeled with PKH26 fluorescent dye. To confirm migration activity after transplantation, recipient embryos were sacrificed and examined on 3 days after transfer. Sex determination was concomitantly undertaken to examine whether sex of recipient embryos could affect the migration activity of gPGCs. All of embryonic gonads examined showed positive signals with PKH26 fluorescence and W-chromosome specific band by polymerase chain reaction (PCR) was detected in male embryos when gPGCs with ZW chromosome were transferred to recipient embryos. In Experiment 2, retrieved gPGCs were transfected with LacZ gene-containing cytomegalovirus promoter ($pCMV{\beta}$) by electroporation and subsequently transferred to recipient embryos. LacZ gene expression was identified in the gonads of 6 or 10-day-old recipient embryos and hatched-chicks. A total of 20 embryos and 12 hatched-chicks were examined and 11 of them (10 embryos and one hatched chicken; 11/32=34.4%) expressed $\beta$-galactosidase, a marker substance of LacZ gene. The results of this study demonstrated that foreign gene-transfected gPGCs can migrate and settle down into the gonad after being transferred into the blood vessel of the recipient embryos. This established technique will contribute to developing a peer biotechnology for transgenic chicken.

Joinability of Tool Steels by TLP Bonding (천이액상확산접합에 의한 합금공구강의 접합특성)

  • 권병대;이원배;김봉수;홍태환;서창제;정승부
    • Journal of Welding and Joining
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    • v.21 no.4
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    • pp.69-74
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    • 2003
  • The mechanical properties of STD11 Joints by using TLP (Transient Liquid Phase Diffusion) bonding method employing MBF-30 and MBF-80 insert metals were investigated with concerning to the microstructural change. TLP bonding of STD 11 was carried out at 1323∼1423K for 0.6ks∼3.6ks in vacuum. The microstructure and the element distribution of the interlayer between tool steels and insert metals showed specific feature with bonding conditions. It was found that the width of the interlayer increased at initial bonding stage. However, the width of interlayer showed nearly constant value during the isothermal solidification. After isothermal solidification was completed, the joint showed homogeneous element distribution and similar microstructure with base metal because of the grain boundary migration to the bonded interlayer. The bonding strength measured by a tensile test has been varied with the bonding conditions. The maximum joint strength, 760MPa, was obtained with the condition of 1423K for 1.2ks using MBF30 insert metal in this experiment.

Quantitative Text Mining for Social Science: Analysis of Immigrant in the Articles (사회과학을 위한 양적 텍스트 마이닝: 이주, 이민 키워드 논문 및 언론기사 분석)

  • Yi, Soo-Jeong;Choi, Doo-Young
    • The Journal of the Korea Contents Association
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    • v.20 no.5
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    • pp.118-127
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    • 2020
  • The paper introduces trends and methodological challenges of quantitative Korean text analysis by using the case studies of academic and news media articles on "migration" and "immigration" within the periods of 2017-2019. The quantitative text analysis based on natural language processing technology (NLP) and this became an essential tool for social science. It is a part of data science that converts documents into structured data and performs hypothesis discovery and verification as the data and visualize data. Furthermore, we examed the commonly applied social scientific statistical models of quantitative text analysis by using Natural Language Processing (NLP) with R programming and Quanteda.

Potential Applications of Low Altitude Remote Sensing for Monitoring Jellyfish

  • Jo, Young-Heon;Bi, Hongsheng;Lee, Jongsuk
    • Korean Journal of Remote Sensing
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    • v.33 no.1
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    • pp.15-24
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    • 2017
  • Jellyfish (cnidarian) are conspicuous in many marine ecosystems when in bloom. Despite their importance for the ecosystem structure and function, very few sampling programs are dedicated to sample jellyfish because they are patchily distributed and easily clogged plankton net. Although satellite remote sensing is an excellent observing tool for many phenomena in the ocean, their uses for monitoring jellyfish are not possible due to the coarse spatial resolutions. Hence, we developed the low altitude remote sensing platform to detect jellyfish in high resolutions, which allow us to monitor not only horizontal, but also vertical migration of them. Using low altitude remote sensing platform,we measured the jellyfish from the pier at the Chesapeake Biological Laboratory in Chesapeake Bay. The patterns observed included discrete patches, in rows that were aligned with waves that propagated from deeper regions, and aggregation around physical objects. The corresponding areas of exposed jellyfish on the sea surface were $0.1{\times}10^4pixel^2$, $0.3{\times}10^4pixel^2$, and $2.75{\times}10^4pixel^2$, respectively. Thus, the research result suggested that the migration of the jellyfish was related to the physical forcing in the sea surface.

In vivo Dendritic Cell Migration Tracking Using Near-infrared (NIR) Imaging (Near-infrared (NIR) 영상기법을 이용한 생체 내 수지상세포의 이동)

  • Lee, Jun-Ho;Jung, Nam-Chul;Lee, Eun Gae;Lim, Dae-Seog
    • KSBB Journal
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    • v.27 no.5
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    • pp.295-300
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    • 2012
  • Matured dendritic cells (DCs) begin migration with their release from the bone marrow (BM) into the blood and subsequent traffic into peripheral lymphoid and non-lymphoid tissues. Throughout this long movement, migrating DCs must apply specialized skills to reach their target destination. Non-invasive in vivo cell-tracking techniques are necessary to advance immune cell-based therapies. In this study, we used a DiD cell-tracking solution for in vivo dendritic cell tracking in naive mice. We tracked DiD (non-invasive fluorescence dye)-labeled mature dendritic cells using the Near Infrared (NIR) imaging system in normal mice. We examined the immunophenotype of DiD-labeled cells compared with non-labelled mature DCs, and obtained time-serial images of NIR-DC trafficking after mouse footpad injection. In conclusion, we confirmed that DiD-labeled DCs migrated into the popliteal lymph node 24 h after the footpad injection. Here, these data suggested that the cell tracking system with the stable fluorescence dye DiD was useful as a cell tracking tool to advance dendritic cell-based immunotherapy.

The Present Status of Cell Tracking Methods in Animal Models Using Magnetic Resonance Imaging Technology

  • Kim, Daehong;Hong, Kwan Soo;Song, Jihwan
    • Molecules and Cells
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    • v.23 no.2
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    • pp.132-137
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    • 2007
  • With the advance of stem cell transplantation research, in vivo cell tracking techniques have become increasingly important in recent years. Magnetic resonance imaging (MRI) may provide a unique tool for non-invasive tracking of transplanted cells. Since the initial findings on the stem cell migration by MRI several years ago, there have been numerous studies using various animal models, notably in heart or brain disease models. In order to develop more reliable and clinically applicable methodologies, multiple aspects should be taken into consideration. In this review, we will summarize the current status and future perspectives of in vivo cell tracking technologies using MRI. In particular, use of different MR contrast agents and their detection methods using MRI will be described in much detail. In addition, various cell labeling methods to increase the sensitivity of signals will be extensively discussed. We will also review several key experiments, in which MRI techniques were utilized to detect the presence and/or migration of transplanted stem cells in various animal models. Finally, we will discuss the current problems and future directions of cell tracking methods using MRI.

Legacy Migration Development Methodology for Construction of Web environment system (웹 환경 시스템 구축을 위한 레거시 마이그레이션 개발방법론)

  • Lee, Jun-Woong;Yang, Hae-Sool
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.8 no.6
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    • pp.1428-1442
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    • 2007
  • Nowadays, as IT environment is changing rapidly, traditional infra system such as hardware, software, and development methodology are changing as well. Legacy system has been filled with Intellectual property such as invested budget and development period for the time of IT is developing. Many countries around the world are having troubles with how to manage the legacy system. It is time to study on a development method and the implementation of supporting tool to reuse or process the legacy system. In this paper, it proves the definition, concept and also background of legacy system by showing real market and technology trend. Developed to handle the concrete development methodology, procedure and reference. We can get more profitability and productivity advance by reuse of legacy system and maintenance cost-saving through legacy migration.

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