• 대한소아치과학회지
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• 제26권2호
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• pp.275-283
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• 1999

저자는 1996년 4월부터 1998년 7월까지 서울대학교병원 소아치과에 내원한 상악정중부 과잉치를 지닌 혼합치열기 및 영구치열기 아동 152명을 대상으로 하여 임상적, 방사선학적 검사를 통해 환아의 연령, 성별과 상악정중부 과잉치의 보유수, 맹출여부, 치관 형태, 위치, 치관 방향과 병발증을 조사하고 상악정중부 과잉치의 양태와 병발증의 상관관계를 chi-square analysis를 이용해 분석하여 다음과 같은 결론을 얻었다. 1. 상악정중부 과잉치로 인한 병발증이 나타나지 않은 경우가 31.6%, 인접 영구전치의 맹출 지연을 야기한 경우가 33.6%, 정중이개가 22.4%, 회전이 8.6%, 전위가 3.3%, 총생이 0.7%이었다. 2. 8.5세 이상 군에 비해 8.5세 미만 군에서 병발증 발생 빈도가 유의성 있게 높았으며(P<0.05), 상악정중부 과잉치가 설측에 위치한 경우에 비해 협측이나 치궁내 위치한 경우에 병발증 발생 빈도가 유의성 있게 높았다(P<0.01). 또 결절형인 경우에 병발증 발생 빈도가 유의성 있게 높았다(P<0.05). 3. 병발증이 나타난 104명을 대상으로 조사한 결과 8.5세 미만 군에서 맹출지연의 빈도가, 8.5세 이상 군인 경우에는 부정교합의 빈도가 유의성 있게 높았고(P<0.05), 상악정중부에 위치하는 경우 부정교합의 빈도가, 편위된 경우에는 맹출지연의 빈도가 유의성 있게 높았다(P<0.01).

• 대한소아치과학회지
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• 제38권2호
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• pp.109-118
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• 2011

두개안면부에서 하악은 태생 4주에 발생하는 첫번째 아가미궁에서 분화되며 맥켈연골이라 알려져 있는 긴 막대기 모양의 연골의 외측부에서 골화가 시작된다. 이후 하악골은 골의 첨가와 흡수에 의해 성장 발육하게 된다. 이런 하악골의 성장 발육이 과하거나 부족한 경우 상하악골의 부조화에 의한 부정교합이 발생되게 되고, 이를 3급 또는 2급 부정교합이라 부른다. 3급 부정교합의 치료를 위해 지금까지 많은 방법들이 사용되어 왔으며, 그중 가장 널리 사용되어지는것이 이모장치이다. Distraction osteogenesis는 강한 힘이나 수술에 의해 분리된 두 개의 골표면 사이에서 새로운 신생골이 형성되는 일련의 생물학적인 과정을 말한다. Distraction force가 callus tissue에 작용되어 골이 분리되면 골과 연조직에 가해지는 신장력이 새로운 골 생성을 자극하게 된다. 이번 연구의 목적은 3차원 유한요소 model을 이용하여 이모장치의 하중에 대한 하악골의 응력분포를 알아보고, 하악골 절개 (mandibular midline distraction) 후 강제변형에 대한 응력분포를 알아보는 것이다.

• 한국조리학회지
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• 제18권1호
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• pp.1-14
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• 2012

본 연구는 여러 가지 생리활성 물질을 가지고 있는 콩식이섬유의 섭취를 증가시키기 위하여 콩식이섬유 SF-1450과 SF-1260을 각각 강력분에 0~12% 첨가하여 식빵을 제조하였다. 콩식이섬유 복합분의 식이섬유 함량은 SF-1450, SF-1260 각각 72.0%, 67.8%이었다. Mixograph 특성은 midline peak height, width at peak, width at 8.00 에서는 콩식이섬유 첨가량이 증가할수록 증가하는 경향을 보였다. 식빵의 비용적은 콩식이섬유 첨가량이 증가할수록 대조구보다 유의적으로 감소하는 경향을 보였다. Crust 색도변화는 콩식이섬유의 첨가량이 증가할수록 각각 L값은 4~12% 첨가구에서 대조구보다 유의적으로 증가하였고 a값은 SF-1450은 6~12% 첨가구, SF-1260은 8~12% 첨가구에서 대조구보다 유의적으로 감소하였으며 crumb 색도변화는 b 값의 경우 대조부보다 유의적으로 증가하였다.(p<0.05). Texture의 특성인 경도의 경우 SF-1450은 10~12% 첨가구에서, SF-1260은 6~12% 첨가구에서 대조구보다 유의적으로 증가하였다. 이상에서 살펴본 바와 같이 콩식이섬유 첨가식빵의 관능특성은 첨가량이 증가함에 따라 대조구보다 품질이 떨어지는 현상을 보였고, 이화학적 분석과 전체적인 기호도를 종합해보면 SF-1450의 경우는 2~4%, SF-1260의 경우는 2% 첨가구의 경우가 우수하게 평가되었다.

• 대한두경부종양학회지
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• 제12권1호
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• pp.16-21
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• 1996

Lymphomatoid granulomatosis, polymorphic reticulosis, midline malignant reticulosis, or lethal midline granuloma have similar histologic features of an angiocentric and angiodestructive lymphoreticular proliferation representing the same nosologic entity. The term 'angiocentric immunoproliferative lesion' (AIL) was proposed by Jaffe, Costa, and Martin. The malignant potential of AILs is originally uncertain, but the facts that AILs have a relatively short survival, and most of them usually progress to an overt malignant lymphoma and survival is inversely proportional to the large, atypical lymphoreticular cells suggest that AILs are malignane. We experienced 17 AILs in nose during 16-year period and retrogradely analized them to recognize the problems in the diagnosis and to establish the further therapeutic strategies. The results were as follows; Twelve of total 17 patients who had diagnosed as histologic grade 1 and 2 had received radiation therapy as an initial treatment and the complete response rate was 91.7%(11/12), but 6 out of 11 had local recurrence and 5 had progress to overt maligant lymphoma within 2years. Three patients with the histologic grade 3 and 2 with unclear histologic grade had received CHOP chemotherapy and there was 1 case with complete response. Two patients with unclear histologic grade had been proved to be malignant histiocytosis by bone marrow biopsy during the clinical course. The overall duration of survival was 2 - 119 months and the 5-year survival rate was 71.9%. And the achievement of initial complete response was the most important prognostic factor of overall survival(P=0.006). Our results suggest that the treatment strategy according to the histologic grading scheme is efficient and more aggressive combination chemotherapy may be necessary to achieve complete response in patients with histologic grade III and II, because most of them progress to overt malignant lymphoma during its process.

• Journal of Korean Neurosurgical Society
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• 제49권6호
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• pp.355-358
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• 2011

Objective : Subdural hygroma (SDG) is a complication occurring after head trauma that may occur secondary to decompressive craniectomy (DC). However, the mechanism underlying SDG formation is not fully understood. Also, the relationship between the operative technique of DC or the decompressive effect and the occurrence and pathophysiology of SDG has not been clarified. Purpose of this study was to investigate the risk factors of SDG after DC in our series. Methods : From January 2004 to December 2008, DC was performed in 85 patients who suffered from traumatic brain injury. We retrospectively reviewed the clinical and radiological features. For comparative analysis, we divided the patients into 2 groups : one group with SDG after craniectomy (19 patients; 28.4% of the total sample), the other group without SDG (48 patients; 71.6%). The risk factors for developing SDG were then analyzed. Results : The mean Glasgow Outcome Scale (GOS) scores at discharge of the groups with and without SDG were 2.8 and 3.1, respectively (p<0.0001). Analysis of radiological factors showed that a midline shift in excess of 5 mm on CT scans was present in 19 patients (100%) in the group with SDG and in 32 patients (66.7%) in the group without SDG (p<0.05). An accompanying subarachnoid hemorrhage (SAH) was seen in 17 patients (89.5%) in the group with SDG and in 29 patients (60.4%) in the group without SDG (p<0.05). Delayed hydrocephalus accompanied these findings in 10 patients (52.6%) in the group with SDG, versus 5 patients (10.4%) in the group without SDG (p<0.05). On CT, compression of basal cisterns was observed in 14 members (73.7%) in the group with SDG and in 18 members of the group without SDG (37.5%) (p<0.007). Furthermore, tearing of the arachnoid membrane, as observed on CT, was more common in all patients in the group with SDG (100%) than in the group without SDG (31 patients; 64.6%) (p<0.05). Conclusion : GOS showed statistically significant difference in the clinical risk factors for SDG between the group with SDG and the group without SDG. Analysis of radiological factors indicated that a midline shifting exceeding 5 mm, SAH, delayed hydrocephalus, compression of basal cisterns, and tearing of the arachnoid membrane were significantly more common in patients with SDG.

• Journal of Korean Neurosurgical Society
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• 제63권5호
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• pp.614-622
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• 2020

Objective : The method of approach during transforaminal endoscopic lumbar discectomy (TELD) has been the subject of repeated study. However, the ideal entry point during TELD has not been studied in detail. Therefore, this study investigated the ideal entry point for avoiding complications using computed tomography (CT) scans obtained from patients in the prone position. Methods : Using CT scans obtained from patients in the prone position, we checked for retroperitoneal or visceral violations and measured the angles of approach with five conventional approach lines drawn on axial CT scans at each disc space level (L2-3, L3-4, and L4-5). We also determined the ideal entry point distance and approach angles for avoiding retroperitoneal or visceral violations. Correlation analysis was performed to identify the patient characteristics related to the ideal entry point properties. Results : We found that the far lateral approach at the L2-3 level resulted in high rates of visceral violation. However, rates of visceral violation at the L3-4 and L4-5 levels were remarkably low or absent. The ideal angles of approach decreased moving caudally along the spine, and the ideal entry point distances increased moving caudally along the spine. Weight, body mass index (BMI), and the depth of the posterior vertebral line from the skin were positively associated with the distance of the ideal entry point from the midline. Conclusion : We reviewed the risk of the extreme lateral approach by analyzing rates of retroperitoneal and visceral violations during well-known methods of approach. We suggested an ideal entry point at each level of the lumbar spine and found a positive correlation between the distance of the entry point to the midline and patient characteristics such as BMI, weight, and the depth of the posterior vertebral line from the skin.

• Journal of Chest Surgery
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• 제32권2호
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• pp.206-210
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• 1999

기관재건술 후 발생한 심부 종격염 2례에 대해 흉골절제, 대위망 자유이식 혹은 전치술, 근피성형술을 병행하여 좋은 결과를 얻었기에 보고한다. 증례 I은 8세된 남아에서 흉골 정중절개로 전방기관성형술을 실시한 후 심부 종격염과 흉골 골수염이 발생한 경우였으며, 증례 II는 50세된 여자에서 상부 흉골의 부분 정중절개로 기관절제 및 단단문합을 실시한 후 종격농양과 흉골 골수염이 발생한 경우였다. 치료는 두례 모두 배농을 시키고 일정기간 세척한 다음, 골수염이 생긴 흉골을 광범위 절제하고 대위망으로 종격을 덮은 후 양측 대흉근을 피부와 함께 박리하여 전흉벽을 재건하였다. 이때 증례 I의 경우는 대위망을 분리한 뒤 횡격막을 통해 종격부위에 위치시켰으며 (in-situ pedicled grafting), 증례 II의 경우는 대위망을 자유이식편으로 만들어 우횡경동맥과 외경정맥에 연결한 후 피하출구을 통해 상부종격에 위치시켰다 (free grafting). 양례 모두 술후 쾌회복하였으며 외래를 통해 추적관찰 중이다.

• 대한치과보철학회지
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• 제32권2호
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• pp.327-353
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• 1994

This study was performed to evaluate the effects of number and alignment of implant fixture and various bar designs on the retention of denture and the stress distribution. Six kinds of photoelastic mandibular models and nine kinds of overdenture specimens were designed. A unilateral vertical load was gradually applied on the right first molar to calculate the maximal dislodgement load of each specimen. A unilateral vertical load of 17 Kgf was applied on the right first molar and a vertical load of 10 Kgf was applied on the interincisal edge region. The stress pattern which developed in each photoelastic model was analyzed by the reflection polariscope. The results obtained were as follows: 1. The maximal dislodgement load reversely increased with the distance from the loading point to the implant fixture, while it linearly increased with that from the most posterior implant fixture to the mesial clip. The maximal dislodgement load also increased with the use of a cantilever bar. 2. Under the posterior vertical load, the stress to the supporting tissue of the denture base increased with the distance from the loading point to the implant future. The stress concentration on the apical area of the implant future reversely increased with the distance from the loading point to the implant future. 3. In the overdentures supported by two implant fixtures under the posterior vertical load. the specimen implanted on lateral incisor areas with a cantilever bar exhibited more favorable stress distribution than that without a cantilever bar. The specimen implanted on the canine areas without a cantilever bar, however, exhibited more favorable stress distribution. 4. In the overdentures supported by three implant fixtures. the specimen implanted ell the midline and canine areas exhibited more favorable stress distribution than that implanted oil the midline and the first premolar areas. 5. In the overdentures supported by four implant fixtures. the specimen implanted with two adjacent implant fixtures exhibited more favorable stress distribution than that implanted at equal distance under the posterior vertical load. 6. Under the anterior vertical load, the overdentures supported by three implant fixtures exhibited stress concentration on the supporting structure of the middle implant future. In overdentures supported by two or four implant futures, no significant difference was noted in stress distribution between the types of bars. These results indicate that the greater the number of implant fixtures, the better the stress distribution is. A favorable stress distribution may be obtained in the overdentures supported by two or three implant fixtures, if the location and the design of the bar are appropriate.

• The Journal of Advanced Prosthodontics
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• 제9권5호
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• pp.371-380
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• 2017

PURPOSE. The aim of this study is to evaluate and compare the stress distribution in Locator attachments in mandibular two-implant overdentures according to implant locations and different loading conditions. MATERIALS AND METHODS. Four three-dimensional finite element models were created, simulating two osseointegrated implants in the mandible to support two Locator attachments and an overdenture. The models simulated an overdenture with implants located in the position of the level of lateral incisors, canines, second premolars, and crossed implant. A 150 N vertical unilateral and bilateral load was applied at different locations and 40 N was also applied when combined with anterior load at the midline. Data for von Mises stresses in the abutment (matrix) of the attachment and the plastic insert (patrix) of the attachment were produced numerically, color-coded, and compared between the models for attachments and loading conditions. RESULTS. Regardless of the load, the greatest stress values were recorded in the overdenture attachments with implants at lateral incisor locations. In all models and load conditions, the attachment abutment (matrix) withstood a much greater stress than the insert plastic (patrix). Regardless of the model, when a unilateral load was applied, the load side Locator attachments recorded a much higher stress compared to the contralateral side. However, with load bilateral posterior alone or combined at midline load, the stress distribution was more symmetrical. The stress is distributed primarily in the occlusal and lateral surface of the insert plastic patrix and threadless area of the abutment (matrix). CONCLUSION. The overdenture model with lateral incisor level implants is the worst design in terms of biomechanical environment for the attachment components. The bilateral load in general favors a more uniform stress distribution in both attachments compared to a much greater stress registered with unilateral load in the load side attachments. Regardless of the implant positions and the occlusal load application site, the stress transferred to the insert plastic is much lower than that registered in the abutment.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제23권3호
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• pp.263-269
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• 2001

하순 및 하악골 정중열은 매우 드문 선천성 기형으로 , 하순절흔에서부터 하악은 물론 경부, 흉부까지 연장되어 다양하게 나타날 수 있으며, 원인은 확실하지 않으나 정중부로의 중배엽의 침투 실패, 하악돌기의 유합부전 그리고 외부 요인들이 논의되고 있다. 치료방법 및 시기에 관해서는 임상소견이 다양하고 증례가 드물기 때문에 많은 논란이 있어왔다. 그러나 현재의 경향은 연조직 기형은 연하 및 발음의 기능적 장애를 예방하기 위하여 가능한 조기에 치료하며, 악골고정을 위한 강선 결찰 혹은 골이식술은 사춘기 후로 미루는 추세이다. 본 교실에서는 저작 장애를 주소로 내원한 8세 여자 환자의 임상소견에서 하악골 정중열과 하순의 수술로 인한 반흔조직 및 하순에서부터 치조골을 가로지르는 섬유성 소대 등을 발견할 수 있었으며, 하악의 정중열을 장골 이식을 이용 하여 양호한 결과를 얻을 수 있었으며, 추후 하순과 순. 설측 전정의 연조직 기형은 심미성과 기능 향상을 위해 부가적인 술식이 필요하리라 생각된다.