• Title/Summary/Keyword: Microemulsion

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Extraction of La(III) by a nonionic microemulsion containing D2EHPA in hollow fiber contactor

  • Ou, Huilin;Gong, Fuzhong;Tang, Yanxia;Luo, Yan;Liu, Liheng
    • Membrane and Water Treatment
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    • v.12 no.2
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    • pp.75-82
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    • 2021
  • This study aimed to prepare a W/O nonionic microemulsion system(MEs) consisting of OP-4[polyoxyethylene(4) nonylphenol], OP-7[polyoxyethylene(7) nonylphenol], 1-hexanol, D2EHPA, kerosene and HCl solution and applied to the extraction of La(III) from chloride aqueous solution within the polysulfone hollow fiber contactor (HFC),laboratory-scale experiments were carried out to investigate the recovery of La(III) using as-prepared microemulsion from the simulation wastewater containing La(III),Al(III) and Fe(III). The right weight ratio(Rs) of OP-4 to OP-7 was firstly confirmed through determination of the solubilization capacity of HCl solution(W0,HCl) in microemulsion, the effect of several factors such as the HCl concentration, temperature and effective extraction time on the extraction efficiency of La(III) was discussed. Results showed that the acceptable Rs was 4:6 to prepare the W/O MEs. The extraction yield of La(III) increased with the increasing of HCl concentration, temperature and effective extraction time and reaches to 97.3% while using five-stage modules. The recovery yield of La(III) from simulation La-bearing wastewater was 90.6%.

Pharmacokinetic and Pharmacological Evaluation of Topical Microemulsion Preparation Containing Piroxicam (마이크로에멀젼으로 제제 설계된 피록시캄 외용제의 약물동력학적 특성 및 약효 평가)

  • 윤범진;박은석;지상철
    • Biomolecules & Therapeutics
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    • v.7 no.1
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    • pp.54-58
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    • 1999
  • The pharmacological activities and pharmacokinetic aspects of a topical microemulsion (KDPM) containing 0.5% piroxicam were evaluated after its topical application compared with a commercially available 0.5% piroxicam gel (R gel). When the pharmacological activities were evaluated with the carrageenan-induced paw edema model, KDPM showed 55.6% edema inhibition, while R gel resulted in 37.1%. With the adjuvant-induced arthritis model, KDFM also resulted in the better pharmacological activities than R gel. The relative bioavailability of KDPM based on R gel was 176% in rabbits.

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A new versatile Microemulsion Gel Technology with flexible Viscosity

  • Ulrich Kux;Jorg Schreiber;Diec, Khiet-Hien;Sabine Ripke;Wittern, Klaus-Peter
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.232-257
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    • 2003
  • It has been shown that transparent microemulsion gels of flexibly adjustable viscosity containing less than 10% w/w surfactants can be obtained just by cooling down through a new 1-step preparation procedure (via 4 different in-situ colloidal systems) using PIT-technology with a range of emulsifiers, co-emulsifiers and lipids. They can be used for a wide scope of applications. Specific examples have been given with antiperspirant formulas that proof the stability of these thickened microemulsions even with high content of electrolytes and low pH. We propose that the structure of these microemulsion gels can be described by cross-linking of nano-fine oil droplets via an ABA-triblock copolymer. A new generation of transparent antiperspirant roll-ons with significantly improved skin tolerance can now be formulated as an attractive alternative to alcohol-based products.

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Microemulsion Processing of Lead Magnesium Niobate Powders

  • Ng, Wei-Beng;John Wang;Ng, Ser-Choon;Gan, Leong-Ming
    • The Korean Journal of Ceramics
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    • v.5 no.3
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    • pp.239-244
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    • 1999
  • Ultrafine lead magnesium niobate $Pb(Mg_{1/3}Nb_{2/3}) O_3$ (PMN) powders have been successfully prepared via a micro-emulsion processing technique. By stepwise hydrolysis using aqueous as the precipitant, hydroxide precursor was obtained from nitrate solutions dispersed in the nanosized aqueous domains of a microemulsion consisting of cyclohexane, non-ionic surfactant (NP5+NP9) and an aueous phase. Upon calcination of the microemulsion-derived precursor at $800^{\circ}C$, PMN powders with 100% perovskite phase was obtained.

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Antioxidative Effect of Crude Anthocyanins in Water-in-Oil Microemulsion System

  • Oh, Ju-Kyoung;Kim, Seok-Joong;Imm, Jee-Young
    • Food Science and Biotechnology
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    • v.15 no.2
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    • pp.283-288
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    • 2006
  • Antioxidative ability of anthocyanins in water-in-oil microemulsion was examined. Microemulsion was prepared by solubilizing crude anthocyanins extracted from grape skin (Cambell early) in organic solvent (hexane) containing anionic surfactant [bis (2-ethylhexyl) sodium sulfosuccinate, AOT] and linolenic acid (10%, w/v). Lipid oxidation significantly decreased with increasing concentration of anthocyanins ($5-20\;{\mu}M$) at micellar phase, and increasing micelle size ($Wo=5-20\;{\mu}M$). At given micelle size (Wo=10), lipid oxidation decreased as number of micelles decreased. These results indicate antioxidative ability of anthocyanins is critically affected by water core and micelle structure formed by surfactant. Interactions between AOT and anthocyanins decreased antioxidative ability of anthocyanins. Antioxidative ability of anthocyanins significantly increased when ${\alpha}$-tocopherol was added into organic phase. This indicates of synergism between the two antioxidants.

Optimal Surfactant Structures for Cosurfactant-Free Microemulsion Systems (III) -Nonylphenol and Tridecyl Alcohol Hydrophobes- (계면활성제의 구조가 Microemulsion 형성에 미치는 영향(제 III보) -친유기 Nonylphenol과 Tridecyl alcohol-)

  • 김천희
    • Journal of the Korean Society of Clothing and Textiles
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    • v.18 no.4
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    • pp.473-479
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    • 1994
  • 보소계면활성제 없이 microemulsion을 형성하는 최적의 계면활성제 구조를 찾기 위한 일련의 연구 중 세번째로 propoxylated nonylphenol sulfates와 ethoxylated 혹은 propoxylated highly-branched tridecyl alcohol sulfates를 연구하였다. 온도, NaCl농도, 보조계면활성제 농도, ethylene oxide몰수(EON), propylene oxide몰수(PON) 등을 변인으로 하여 phase behavior 실험을 한 결과 tridecyl alcohol 친유기를 갖는 계면활성제가 보조계면활성제 없이 microemulsion을 형성하였다. $C_{13}O(EO)_mPO)_nSO_3Na$ 일반식으로부터 m과 n을 변경시킴으로써 계의 다양한 조건을 만족시키는 계면활성제를 디자인할 수 있었다.

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Fluorescent Silk Fibroin Nanoparticles Prepared Using a Reverse Microemulsion

  • Myung, Seung-Jun;Kim, Hun-Sik;Kim, Yeseul;Chen, Peng;Jin, Hyoung-Joon
    • Macromolecular Research
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    • v.16 no.7
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    • pp.604-608
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    • 2008
  • Color dye-doped silk fibroin nanoparticles were successfully fabricated using a microemulsion method. An aqueous silk fibroin solution was prepared by dissolving cocoons (Bombyx mori) in a concentrated lithium bromide solution followed by dialysis. A color dye solution was also mixed with the aqueous silk fibroin solution. The surfactants used for the microemulsion were then removed by methanol and ethanol, yielding color dye-doped silk fibroin nanoparticles, approximately 167 nm in diameter. The secondary structure of the nanoparticles showed a $\beta$-sheet conformation, as characterized by Fourier transform infrared spectroscopy. The morphology of the nanoparticles was determined by field emission scanning electron microscopy, transmission electron microscopy and atomic force microscopy, and their size and size distribution were measured by dynamic light scattering. The color dye-doped silk fibroin nanoparticles were examined by confocal laser scanning microscopy.

Transdermal Delivery of Piroxicam Using Microemulsions

  • Park Eun-Seak;Cui Yu;Yun Bum-Jin;Ko In-Ja;Chi Sang-Cheol
    • Archives of Pharmacal Research
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    • v.28 no.2
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    • pp.243-248
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    • 2005
  • To improve the skin permeability of piroxicam, a new oil-in-water microemulsion containing $0.5\%$ piroxicam was developed. Among various oils investigated for their suitability as an oil phase for the microemulsion system, oleic acid showed both excellent solubility and skin permeation enhancing effect for piroxicam. Microemulsion existence ranges were identified through the construction of the pseudo-ternary phase diagram. The effect of the content of oleic acid and the ratio of the surfactant/cosurfactant on skin permeation of piroxicam were evaluated with excised rat skins. The optimum formulation with the highest skin permeation rate ($47.14\;{\mu}g/cm^2/h$) consisted of $0.5\%$ piroxicam, $10\%$ oleic acid, $60\%$ Labrasol/ethanol (1:5) and water.

Fabrication Technique of Nanoemulsion Using Silicone Oil and Application as Hydrophilic Ophthalmic Lens

  • Hye-In Park;A-Young Sung
    • Korean Journal of Materials Research
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    • v.34 no.7
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    • pp.315-320
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    • 2024
  • In order to maximize the function and increase the compatibility of silicone hydrogel lens, this study compared and analyzed the properties of Amino modified silicone oil using mini and microemulsion technique, respectively. Optical and physical properties were evaluated by spectral transmittance, refractive index, water content, oxygen transmittance and contact angle measurements to evaluate the performance of the manufactured hydrogel lens. The spectral transmittance results revealed the copolymerization method lens showed 31 % of the visible light area, which did not satisfy the basic optical properties. However, the lens using the mini and microemulsion materials showed more than 90 % of the visible light area, satisfying the optical characteristics. In addition, all physical properties were superior to a basic hydrogel lens. The mini and microemulsion techniques effectively improved the stability and function of the ophthalmic hydrogel lens and are considered a promising ways of manufacturing an ophthalmic hydrogel contact lens with increased compatibility and stability.

Refractive Index Matching and Clear Emulsions

  • Sun, James-Ziming;James W. Parr
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.374-386
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    • 2003
  • Two ways of making clear emulsions\ulcornerMicroemulsion Visible light λ = 400-700 nm Microemulsion, d < 50 nmㆍRefractive Index Matching(omitted)

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