DOI QR코드

DOI QR Code

Fabrication Technique of Nanoemulsion Using Silicone Oil and Application as Hydrophilic Ophthalmic Lens

  • Hye-In Park (Department of Optometry & Vision Science, Daegu Catholic University) ;
  • A-Young Sung (Department of Optometry & Vision Science, Daegu Catholic University)
  • Received : 2024.05.28
  • Accepted : 2024.06.20
  • Published : 2024.07.27

Abstract

In order to maximize the function and increase the compatibility of silicone hydrogel lens, this study compared and analyzed the properties of Amino modified silicone oil using mini and microemulsion technique, respectively. Optical and physical properties were evaluated by spectral transmittance, refractive index, water content, oxygen transmittance and contact angle measurements to evaluate the performance of the manufactured hydrogel lens. The spectral transmittance results revealed the copolymerization method lens showed 31 % of the visible light area, which did not satisfy the basic optical properties. However, the lens using the mini and microemulsion materials showed more than 90 % of the visible light area, satisfying the optical characteristics. In addition, all physical properties were superior to a basic hydrogel lens. The mini and microemulsion techniques effectively improved the stability and function of the ophthalmic hydrogel lens and are considered a promising ways of manufacturing an ophthalmic hydrogel contact lens with increased compatibility and stability.

Keywords

References

  1. J. W. Heo, S. M. Shin and A. Y. Sung, Korean J. Vis. Sci., 22, 435 (2020).
  2. M. J. Lee, S. Y. Park and A. Y. Sung, Micromachines, 13, 1897 (2022).
  3. J. W. Heo, S. M. Shin, D. W. Kim and A. Y. Sung, Korean J. Vis. Sci., 24, 43 (2022).
  4. N. P. D. Tran and M. C. Yang, Polymers, 11, 944 (2019).
  5. Y. L. Kim, S. H. Mun, S. J. Park and Y. R. Kim, in Proceedings of the KSAM 2016 Spring Conference (Jeonju, April 2016) p. 233-234.
  6. H. J. Lee and J. H. Kim, Chem. Ind. Technol., 14, 529 (1996).
  7. N. Anton and T. F. Vandamme, Pharm. Res., 28, 978 (2011).
  8. W. Kwon, M. K. Lee, E. G. Jeong and J. S. Bae, Text. Color. Finish., 30, 256 (2018).
  9. P. C. Nicolson and J. Vogt, Biomaterials, 22, 3273 (2001).
  10. W. G. Cho, J. Korean Appl. Sci. Technol., 29, 238 (2012).
  11. W. Y. Jung, Y. H. Han, G. D. Lee, S. S. Park and S. S. Hong, Appl. Chem. Eng., 19, 351 (2008).
  12. W. G. Cho, J. Soc. Cosmet. Sci. Korea, 37, 1 (2011).
  13. W. Kwon, M. K. Lee, E. G. Jeong and J. S. Bae, Text. Color. Finish., 30, 256 (2018).
  14. H. J. Yu and C. U. Park, Preparation method of microemulsion of amino-modified silicone oil, WO2011025325, March 3, 2011.
  15. W. Y. Shin and H. M Lee, J. Korean Ophthalmic Opt. Soc., 28, 191 (2023).
  16. C. Huh and S. G. Mason, J. Colloid Interface Sci., 60, 11 (1977).