• KSBB Journal
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• v.5 no.3
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• pp.269-277
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• 1990

Methylobacillus sp. SK1, an obligate methylotroph, was cultivated in a fed-batch culture using DO as a methanol feeding indicator with a micro computer-aided control system. While 2.07g/l of cell density was obtained after 13 hr in the batch culture (initial methanol concentration: 1.0%(v/v)),45.3g/l of cell density was obtained after 17 hr by feeding methanol and metal ions in the fed-batch culture with oxygen supply. The high-density biomass was obtained in short cultuivation time by fed-batch culture with feedback control, and consequently the biomass productivity was significantly increased. It was mainly due to extension of logarithmic growth period by methanol feeding without methanol inhibition and intensive aeration without DO limitation with microcomputer-aided control system.

• Journal of Biosystems Engineering
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• v.32 no.6
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• pp.440-447
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• 2007

In this study, a biosensor was developed using an enzyme-linked immunosorbent assay (ELISA) to rapidly measure the fungicide iprovalicarb residues in agricultural products. The biosensor was designed to include micro-pumps and solenoid valves for fluid transport, a spectrophotometer cuvet as a reaction chamber, a photodiode with a light-emitting diode for optical density measurement, and a control microcomputer to implement assay. The rate of change in optical density of the cuvet was read as final signal output. Micro-pumps were evaluated to investigate their delivery capability, the highest values of the error and the coefficient of variation were 4.3% and 4.6% respectively. As the incubation period was reduced from 15 minutes to 11 minutes to shorten the total processing time, the sensor sensitivity was decreased as the antibody dilution ratio was reduced to a half. The maximum usable period of the coated cuvet was found to be two days with 1% error limit. To predict the concentration of the iprovalicarb residue in agricultural products, a linear calibration model was obtained with r-square values of 0.992 for potato and 0.985 for onion. In validation test for the samples of potatoes and onions against the high performance liquid chromatography, very high correlation values were obtained as 0.996 and 0.993 respectively. Using the cuvet immobilized with antigen, it took 21-minutes for the biosensor to complete the measuring process of the iprovalicarb residues.

• Journal of Biosystems Engineering
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• v.30 no.2 s.109
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• pp.127-133
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• 2005

Precision tillage is designed to till lands variably according to their firmness. Therefore, it is necessary to measure soil firmness in fields and present it in a form with which the variable tillage on be performed. Such forms may be classified into two categories: sensor-based and map-based forms. The map-based approach appears to be inevitable until the technology develops high enough to secure the sensor-based approaches. The first step for map-based precision tillage may be to develop a tillage recommendation map. In this study, a tractor-mountable automatic soil firmness measurement system was developed to construct a cone index map. The system is comprised of three ASAE Standard cone penetrometers and a hydraulic unit for controlling operation of the penetrometers. The system is designed to conduct stop-and-go measurements in fields. The measurements from the three penetrometers are transferred to a microcomputer and the average cone index was calculated. This average cone index was taken as soil firmness of the location where the measurement was made. The cone indices thus determined were used to construct a cone index map using the ArcView software. The system also displays the soil penetration resistance, cone index and soil depth as the cone penetrates into the soil. The field performance of the system was evaluated and the cone index maps at different depths were also presented.

• Journal of Biosystems Engineering
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• v.13 no.2
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• pp.38-45
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• 1988

This study was intended to develop the system automatically controlling travel direction of combine by means of sensing paddy rows. The control system was composed of three detecting levers having different length, micro-switch, microcomputer and electro-hydraulic control system. Sensor and control system developed was tested to estimate optimum design values and its actual performance as installed in combine. The computer simulation and performance test at simulated and actual field were conducted to test for possibility of practical use. The results of the study arc summarized. as follows: 1. The travel traces of combine hiving the conventional sensor with 2 levers and the new sensor detecting the slope of paddy rows were compared through computer simulation. Turning frequency of combine having new sensor was fewer than that of conventional sensor, but the rate of turning for the combine with new sensor was much greater than that of conventional sensor. 2. As sensor was established behind the tip of divider, the sensor itself well followed paddy rows but the tip of divider did not, resulting in divider being deviated from paddy rows. It was analyzed that the sensor should be attached closer to the tip of divider to have a better performance of the control system. 3. The greater the length of sensor lever for given location of sensor attachment and combine forward speed, the higher sensitivity of turning in control system. Moreover, increasing combine speed resulted in a worse performance of control system following paddy rows. Consequently, it was necessary that an optimum length of sensor attachment and for the range of combine operational speed. 4. Field test of combine installed with the sensor and electro-hydraulic system developed in this study showed that it may be operated smoothly and well behaved to paddy rows to 4th gear of combine speed which was 59cm/s. Consequently. it was concluded that the combine with the guidance control system developed in this study may be successfully used for paddy combining.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.32 no.3
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• pp.266-272
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• 1996

The distribution and abundance of fish in the Cheju southeastern area was studied by the combined hydroacoustic and bottom trawl surveys in April 1994 and in July 1995, respectively. The main purpose of these investigations was to provide the basic data for this management and the biomass estimation of commercially important demersal fish stocks in this area. The hydroacoustic surveys were performed by using a 50 kHz scientific echo sounder system with a microcomputer-based echo integrator. Acoustical measurements of fish abundance and distribution were conducted along the cruise tracks of research vessel and during all trawl hauls by continuous echo sounding. The average weight-normalized target strength for demersal fish aggregations was derived from the relationship between the mean volume backscattering strength for the depth strata of trawl hauls and the weight per cubic meter of trawl catches. The geographical distribution of fish stocks in the 1994 survey area was investigated in relation to oceanographic conditions. The results obtained can be summarized as follows: 1. From the 1994 and 1995 survey data, the relationship between the mean volume backscattering strength (, dB) for the depth strata of trawl hauls and the weight (W, kg/$m^3$) per cubic meter of trawl catches was expressed by the following equation = - 32.8+ lOlog(W) The average weighted-target strength value at 50 kHz derived from this equation was .. 32.8 dB/kg. 2. In 1994 and 1995, both surveys showed a trend of decreasing fish abundance toward the southern area of the Cheju Island with high densities offish along the west coast ofth.e Tsushima Island. The highest demersal concentrations in the southern area of the CheJu Island appeared in bottom waters colder than $12^{\circ}C.$. . 3. From the results of combined bottom trawl and hydroacoustic surveys, the estunated fish densities in the southeastern area of the Cheju Island were 1.5488 x $10^-4$kg/$m^3$ in the 1994 surveyand 1.9498 x $10^-4$kg/$m^3$ in the 1995 survey, respectively.

• Journal of the Korean Electrochemical Society
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• v.8 no.1
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• pp.1-5
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• 2005

Electric double layer capacitors(EDLCS) based on the charge stored at the interface between a hi팀 surface area carbon electrode and an organic electrolyte solution are widely used as a maintenance-free power source for IC memories and microcomputers. The achievement of the excellent performance of the capacitor requires an electrolyte solution which provides high conductivities over a wide temperature range and good electrochemical stabilities to allow the capacitor to be operated at high voltage. The electrochemical capacitor using a carbon material as electrodes and using an organic electrolyte with $1M-LiPF_6$ in PC-GBL-DEC(volume ratio 1:1:2) has specific capacitance of 64F/g.

• Journal of the Korean Institute of Telematics and Electronics
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• v.27 no.2
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• pp.55-64
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• 1990

This paper concerned about a study on the direct pole placement PID self-tuning controller design for DC servo motor control system. The method of a direct pole placement self-tuning PID control for a DC servo motor of Robot manipulator tracks a reference velocity in spite of the parameters uncertainties in nonminimum phase system. In this scheme, the parameters of classical controller are estimated by the recursive least square (RLS)identification algorithm, the pole placement method and diophantine equation. A series of simulation in which minimum phase system and nonminimum phase system are subjected to a pattern of system parameter changes is presented to show some of the features of the proposed control algorithm. The proposed control algorithm which shown are effective for the practical application, and experiments of DC servo motor speed control for Robot manipulator by a microcomputer IBM-PC/AT are performed and the results are well suited.

• YAKHAK HOEJI
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• v.42 no.5
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• pp.513-518
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• 1998

Fluoxetine is a nontricyclic antidepressant which blocks serotonin reuptake selectively. Its N-demethyl metabolite, norfluoxetine is also selective inhibitor of serotonin uptake . This study was carried out to compare the bioavailability of Myung-in fluoxetine (20mg/cap.) with that of Prozac$^{\circde{R}}$. The bioavailability was conducted on 24 healthy volunteers who received a single dose (80mg) of each drug in the fasting state, in a randomized balanced 2-way crossover design. After closing, serial blood samples were collected for a period of 48 hours, Plasma was analyzed for fluoxetine and norfluoxetine by a sensitive and validated HPLC assay. The major pharmacokinetic parameters ($AUC_{0-48\;hr}$, Cmax, Tmax , $AUC_{inf.}$, MRT. $T_{1/2}$, Vd and Cl) were, calculated from the plasma fluoxetine concentration-time data of each volunteer. The microcomputer program, 'WinNonlin' was used for compartmental analysis. A two-compartment model with first-order input, first-order output and no lag time was chosen as the most appropriate pharmacokinetic model. The data were best described by using a weighting factor of $1/y^2$. Though the plasma fluoxetine concentrations of Myung-in fluoxetine were higher than those of Prozac$^{\circde{R}}$ at all observed time from 7.9% to 16.9% (P<0.05 at 6.7 and 10 hr), the bioavailability of Myung-in fluoxetine appeared to be bioequivalent with that of Prozac$^{\circde{R}}$. There were no statistical significant differences between the two drugs in all pharmacokinetic parameters including $AUC_{0-48\;hr}$ of norfluoxetine.

• The Journal of the Korea institute of electronic communication sciences
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• v.4 no.1
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• pp.53-59
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• 2009

By the use of open source and 16bit Microcomputer, IDB(Integrated Development Board) for embedded technical education was designed and developed. Based on 16bit MCU H8/300H, LED, LED Matrix, motors, sensors and various I/O circuitry, and the connection to a computer via the SCI, and $16{\times}2$ character LCD was designed and implemented on IDB. In addition, the software development environment was build by the assembler and H8 C compiler which is provided to the open-source software. And memory expansion was considered to include TRON(Real time OS) and uClinux. To verify the developed board, IDB was fabricated by PCB machine, and the fuction was confirmed by the basic I/O control program.

• Journal of Information Technology Applications and Management
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• v.20 no.4
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• pp.235-247
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• 2013

The evolution of information technology and proliferation of hospital management and managerial applications of computing has led to change in the characteristics, uses and evaluations of software for the hospital management. With the growing proliferation of microcomputer use and the value-added for management strategies, more and more software has been massively developed, produced and distributed for the hospital industry. The user is faced with an increasingly difficult choice in the evaluation and selection of software. For many reasons, users frequently must rely on expert evaluations of the technical functions and quality of software. The objectives of this study are to provide selection criteria for an Electronic Medical Record (EMR) and to develop an evaluation framework for the Hospital Information Systems. The major findings of our study are as follows (1) the identification of EMR evaluation characteristics (2) the design and development of EMR selection model and (3) the evaluation of the importance for EMR characteristics using Analytic Hierarchy Process (AHP). We identify 6 characteristics and 22 sub-characteristics of the EMR, calculate their weights, and decide the best configuration. Especially, the AHP methodology can be applied to gather knowledge from multiple experts. Because AHP can 1) facilitate the participation of multiple experts 2) increase group productivity and therefore result in both quantitatively and qualitatively superior outcomes than that of a single individual's work 3) provide a mechanism for reconciling conflict from multiple expert 4) validate the acquired knowledge, providing consistency of facts, and 5) enhance the accuracy reliability of the acquired knowledge increase through of the reliability provided by consensus across multiple experts. Although some further research is required, the proposed model can be regarded as a basis for the selection of EMR.