• Title/Summary/Keyword: Micro-mixing

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Optimal Fuzzy Sliding-Mode Control for Microcontroller-based Microfluidic Manipulation in Biochip System

  • Chung, Yung-Chiang;Wen, Bor-Jiunn
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.196-201
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    • 2004
  • In biometric and biomedical applications, a special transporting mechanism must be designed for the ${\mu}$TAS (micro total analysis system) to move samples and reagents through the microchannels that connect the unit procedure components in the system. An important issue for this miniaturization and integration is microfluid management technique, i.e., microfluid transportation, metering, and mixing. In view of this, this study presents an optimal fuzzy sliding-mode control (OFSMC) design based on the 8051 microprocessor and implementation of a complete microfluidic manipulated system implementation of biochip system with a pneumatic pumping actuator, a feedback-signal photodiodes and flowmeter. The new microfluid management technique successfully improved the efficiency of molecular biology reaction by increasing the velocity of the target nucleic acid molecules, which increases the effective collision into the probe molecules as the target molecules flow back and forth. Therefore, this hybridization chip was able to increase hybridization signal 6-fold and reduce non-specific target-probe binding and background noises within 30 minutes, as compared to conventional hybridization methods, which may take from 4 hours to overnight. In addition, the new technique was also used in DNA extraction. When serum existed in the fluid, the extraction efficiency of immobilized beads with solution flowing back and forth was 88-fold higher than that of free-beads.

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Inhibitory Effect of Disinfectants and Antibiotics on Rusty-root Symptoms in Panax Ginseng C. A. Meyer (소독제 및 항생제의 적변삼 발생 억제 효과)

  • Park, Hong-Woo;Lee, Eun-Jeong;Choi, Jae-Eul
    • Korean Journal of Medicinal Crop Science
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    • v.14 no.6
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    • pp.336-341
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    • 2006
  • The endophytic bacteria were isolated from the rusty-root ginseng. This isolated bacteria were occurred the rusty-root ginseng with artificial inoculation. For the suppressing of rusty-ginseng, disinfectants, antibiotics, kitosan, micro-organisms and metabolites were tested to isolated endophytic bacterium. All of the isolated bacteria strains were sensitive sodium hypochlorite, however, some of isolated bacteria lines were sensitive to other tested materials. For example, D (didecyl dimethyl ammonium bromide), CIO$_2$, ODDA (octyldecyl dimethyl ammonium chloride + diocyul dimethyl ammonium chloride + alkyl diethyl benzyl ammonium chloride), GD (glutaraldehyde + dimethy cocobenzyl ammonium chloride) suppressed some of bacteria strains. Otherwise, some of antibiotics (e.g. ampicillin, chloramphenicol, erythromycin, kanamycin, neomycin, rifampin, streptomycin, tetracycline) were sensitive to the isolated bacteria strains. All of isolated bacteria strainswere inhibitive to the mixed formation with neomycin and streptomycin, and neomycin and tetracycline. Both sodium hypochlorite and antibiotic mixing of neomycin and tetracycline were effective to prevention of rusty-root ginseng of sub-merging ginseng in the ginseng field.

A Study on the Removal Characteristics of Dissolved Organic and Ammonia Compounds in PFR of Aerated Submerged Bio-film (ASBF) Reactor (PFR 공정의 ASBF 구조에 의한 유기물제거와 질산화의 영향에 대한 연구)

  • Choi, Young-Ik
    • Journal of Environmental Science International
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    • v.17 no.11
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    • pp.1265-1271
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    • 2008
  • Aerated submerged bio-film (ASBF) pilot plant has been developed. The presented studies optimized an inexpensive method of enhanced wastewater treatment. The objectives of this research were to describe pilot scale experiments for efficient removal of dissolved organic and nitrogen compounds by using ASBF reactor in plug-flow reactor (PFR) and improve understanding of dissolved organic matter and nitrogen compounds removal rates with dynamic relationships between heterotrophs and autotrophs in the fixed-film reactor. This research explores the possibility of enhancing the performance of shallow wastewater treatment lagoons through the addition of specially designed structures. This direct gas-phase contact should increase the oxygen transfer rate into the bio-film, as well as increase the micro-climate mixing of water, nutrients, and waste products into and out of the bio-film. This research also investigated the efficiency of dissolved organic matter and ammonia nitrogen removals in the ASBF. As it was anticipated, nitrification activity was highest during periods when the flow rate was lower, but it seemed to decline during times when the flow rate was highest. And ammonia nitrogen removal rates were more sensitive than dissolved organic matter removal rates when flow rates exceeded 2.2 L/min.

The Synthesis and Characterization of Mesoporous Microbead Incorporated with CdSe/ZnS QDs (양자점이 고밀도화된 마이크로 비드의 제조 및 특성)

  • Lee, Ji-Hye;Hyun, Sang-Il;Lee, Jong-Huen;Koo, Eun-Hae
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.25 no.8
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    • pp.657-663
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    • 2012
  • The spherical mesoporous silica is synthesized and incorporated with CdSe/ZnS quantum dots(QDs) for preparing micro beads to detect toxic and bio-materials with high sensitivity. The spherical silica beads with the brunauer-emmett-telle(BET) average pore size of 15 nm were prepared with a ratio 1, 3, 5-trimethylbenzen, as a swelling agent, to the block-copolymer template surfactant of over 1 and under vigorous mixing condition. The surface of spherical mesoporous silica is modified using octadecylsilane for incorporating QDs. Based on photoluminescence(PL) spectra, the relative brightness of mesoporous silica beads incorporated with 10 nM of QDs is 79,000 times brighter than that of Rodamine 6 G.

DISCRETE PARTICLE SIMULATION OF DENSE PHASE PARTICULATE FLOWS

  • Tsuji Y.
    • 한국전산유체공학회:학술대회논문집
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    • 2005.10a
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    • pp.11-19
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    • 2005
  • First, methods of numerical analysis of gas-particle flows is classified into micro, meso and macro scale approaches based on the concept of multi-scale mechanics. Next, the explanation moves on to discrete particle simulation where motion of individual particles is calculated numerically using the Newtonian equations of motion. The author focuses on the cases where particle-to-particle interaction has significant effects on the phenomena. Concerning the particle-to-particle interaction, two cases are considered: the one is collision-dominated flows and the other is the contact-dominated flows. To treat this interaction mathematically, techniques named DEM(Distinct Element Method) or DSMC (Direct Simulation Monte Carlo) have been developed DEM, which has been developed in the field of soil mechanics, is useful for the contact -dominated flows and DSMC method, developed in molecular gas flows, is for the collision-dominated flows. Combining DEM or DSMC with CFD (computer fluid dynamics), the discrete particle simulation becomes a more practical tool for industrial flows because not only the particle-particle interaction but particle-fluid interaction can be handled. As examples of simulations, various results are shown, such as hopper flows, particle segregation phenomena, particle mixing in a rotating drum, dense phase pneumatic conveying, spouted bed, dense phase fluidized bed, fast circulating fluidized bed and so on.

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Characteristics of Plasma Damage and Recover in PZT Films by Dry Etching (건식식각에 의한 PZT 박막의 플라즈마 손상 및 회복특성)

  • 강명구;김경태;김동표;김창일
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.07a
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    • pp.375-378
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    • 2002
  • We investigated the reduction of etching damage by additive O$_2$ in etching gas and recovery of etching damage by O$_2$ annealing. The PZT thin films were etched using additive Ar or O$_2$ into Cl$_2$/CF$_4$ gas mixing ratio of 8/2. In order to recover ferroelectric properties of PZT thin films after etching, the etched PZT thin films were annealed at 600 C in O$_2$ atmosphere for 10 min. The remanent polarization is decreased seriously and fatigue is accelerated in the PZT sample etched in Ar/(C1$_2$+CF$_4$) plasma, whereas these characteristics are improved in O$_2$/(Cl$_2$/CF$_4$). From x-ray photoelectron spectroscopy (XPS) analysis, the intensities of Pb-O, Zr-O and Ti-O peaks are changed and the etch byproducts such as metal chloride and metal fluoride are reduced by O$_2$ annealing. From electron probe micro analyzer (EPMA) and auger electron spectroscopy(AES), O$_2$ vacancy is observed after etching. In x-ray diffraction (XRD), the structure damage in the additive O$_2$ into C1$_2$/CF$_4$ is reduced and the improvement of ferroelectric behavioral annealed sample is consistent with the increase of the (100) and (200) PZT peaks.

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A Study on the Flame Structure and Combustion Charactexistics of a Premixed Flame Stabilized by a Streamline Step( $\Pi$) (유선형 스텝에 의해 안정화된 예혼합화염의 구조와 연소특성에 관한 연구 ($\Pi$))

  • 이재득;최병륜
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.14 no.6
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    • pp.1661-1668
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    • 1990
  • In a turbulent premixed flame stabilized by the streamline step, and dominated by a coherent eddy, a flame micro-structure was investigated with analyzing the signals of temperature, the ion current, and schieren phtographs simultaneously. Generally the contours of large scale coherent eddies of schlieren photographs was considered as the flame front, however, the main reaction can be occurred within the eddy as a structure of fine flamelets scale. The surrounding burned gas of flamelets could not propagate to a unburned mixture, obstructing flamelets from propagating to a unburned mixture. Consequently, it could restrain flashback. The main reaction region was found to be located at higher temperature of the burned gas rather than at maximum rms of fluctuating temperature. The peak probability of higher temperature was 6 times greater than that of lower temperature. As it was difficult to infer a flame structure from PDF distribution of the fluctuating temperature in form of bimodal shape, it should be taken into consideration with other informations related to the sensitive flame front, for instance, ion current.

Noise Reduction of a Underexpanded Supersonic Jet via Steady Blowing with Microjets (소형제트를 이용한 과소팽창 음속 제트에서의 소음저감)

  • Kim Jin-Hwa;Kim Jung Hoon;Yoo Jung Yul
    • Proceedings of the KSME Conference
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    • 2002.08a
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    • pp.747-750
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    • 2002
  • An attempt to reduce supersonic Jet noise is carried out by using two steady microjets in a round jet. The jet is issued from a round sonic nozzle with an exit diameter of 10mm. Two micro-nozzles with an inside diameter of 1mm each are installed on the exit plane with an off-axis angle of $45^{\circ}$. Far-field noise was measured at a location 40 diameters off the jet axis. The angles between a microphone and the jet axis are $45^{\circ}\;and\;90^{\circ}$. For an injection rate less than $1{\%}$ of the main jet, screech tones were completely suppressed by the microjets. The reduction in the ovelall sound pressure levels were $2.4\;and\;2.7\;dB\;for\;90^{\circ}\;and\;45^{\circ}$ directions, respectively. The enhancement of mixing/spreading of the jet by the microjet was negligible. The reduction of noise is probably due to distorted shock cell structures and/or broken large scale vortical structures by the microjets.

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White-light-emitting Organic Electroluminescent Device Based On Incomplete Energy Transfer

  • Song, Tae-Joon;Ko, Myung-Soo;Lee, Sung-Soo;Cho, Sung-Min
    • 한국정보디스플레이학회:학술대회논문집
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    • 2002.08a
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    • pp.701-705
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    • 2002
  • In order to realize full color display, two approaches were used. The first method is the patterning of red, green, and blue emitters using a selective deposition. Another approach is based on a white-emitting diode, from which the three primary colors could be obtained by micro-patterned color filters. White-light-emitting organic light emitting devices (OLEDs) are attracting much attention recently due to potential applications such as backlights in liquid crystal displays (LCDs) or other illumination purposes. In order for the white OLEDs to be used as backlights in LCDs, the light emission should be bright and have Commission Internationale d'Eclairage (CIE) chromaticity coordinates of (0.33, 0.33). For obtaining white emission from OLEDs, different colors should be mixed with proper balances even though there are a few different methods for mixing colors. In this study, we will report a white organic electroluminescent device based on an incomplete energy transfer. In which the blue and green emission come from the same layer via incomplete energy transfer.

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A Study on the Physical Properties of Recycled Asphalt Mixtures Using Glass Fiber Reinforcement (유리섬유 보강재를 이용한 재활용 아스팔트 혼합물의 물리적 특성에 관한 연구)

  • Park, Ki Soo;Yoo, Pyeong Jun
    • International Journal of Highway Engineering
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    • v.20 no.4
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    • pp.27-34
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    • 2018
  • PURPOSES : The objective of this study is to evaluate the physical properties of recycled asphalt mixtures reinforced with glass fiber. METHODS : Firstly, mixing design was conducted on recycled asphalt mixture for use of 50% recycled aggregate. Various laboratory tests were performed on four types of recycled asphalt mixtures with different glass fiber content to evaluate the physical properties. The laboratory tests include indirect tensile strength test, dynamic modulus test, Hamburg wheel tracking test and tensile-strength ratio to evaluate cracks, rutting and moisture resistance of mixtures. RESULTS : The indirect tensile strength of fiber reinforced glass increased about 139.4%. As a result of comparing the master curves obtained by the dynamic modulus test, the elasticity was low in the low temperature region and high in the high temperature region when the glass fiber was reinforced. The glass fiber contents of PEGS 0.3%, Micro PPGF 0.1% and Macro PPGF 0.3% showed the highest moisture resistance and rutting resistance. CONCLUSIONS : The test results show that use of glass fiber reinforcement can increase the resistance to cracking, rutting, and moisture damage of asphalt mixtures. It is also necessary to validate the long-term performance of recycled asphalt mixtures with glass fiber using full scale pavement testing and field trial construction.