• Title/Summary/Keyword: Micro Needle

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Effect of Discharge Electrode Shape of a Barrier Discharge Type Gas Pump on Ionic Wind Generation (장벽 방전형 공기 펌프의 이온풍 발생에 미치는 방전전극 형상의 영향)

  • Hwang, Deok-Hyun;Moon, Jae-Duk
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.5
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    • pp.994-998
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    • 2009
  • Existing cooling technologies no longer provide adequate heat dissipation due to excessive heat generation caused by the growing component density on electronic devices. An ionic gas pump can be used for the thermal management of micro-electronic devices, since the size of pump can be reduced to a micrometer scale. In addition, the gas pump allows for gas flow control and generation without moving parts. This ideal property of gas pump gives rise to a variety of applications. However, all these applications require maximizing the wind velocity of gas pump. In this study a barrier discharge type gas pump, with a needle-shaped corona electrode instead of a plate-shaped corona electrode, has been investigated by focusing on the corona electrode shape on the wind velocity and wind generation yield. As a result, the enhanced wind velocity and wind generation yield of 1.76 and 3.37 times were obtained with the needle-shaped corona electrode as compared with the plate-shaped corona electrode of the proposed barrier discharge type gas pump.

A study on the TiN coating applied to a rolling wire probe

  • Song, Young-Sik;S. K. Yang;Kim, J.
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2003.10a
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    • pp.118-118
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    • 2003
  • In a rolling wire probe, a key component of an inspection apparatus for PDP electrode patterns, the electric performance of it is known to be strongly dependent on the surface condition of a collet pin, a needle pin, and a wire. However, the collet and needle pins rotate very rapidly in contact with each other, which results in the degradation of the surface by the heat and friction and finally the formation of black wear marks on the surface after a several hundred hours test. Once the black wear marks appear on the surface, the electric resistance of the probe increases sharply and so the integrity of the probe is severely damaged. In this experiment, TiN coating, which has excellent electric conductances and good wear-resistance, has been applied on the surface of collect and needle pins for preventing the surface damages. In order to achieve the homogeneous coating with a good adhesion property, special coating substrate stages and jigs were designed and applied during coating. TiN has been deposited using 99.999% Titanium target by a DC reactive sputtering method. According to the components and jigs, processing parameters, such as DC power, RF bias and the flow rate ratio of Ar and N$_2$ used as reactive gases, has been controlled to obtain good TiN films. Detailed problems and solutions for applying the new substrate stages and jigs will be discussed.

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Fabrication of Rapidly Solidified Al-20wt%Si-5wt%Fe Alloy Powder and Mechanical Properties of its Extrudates (급속응고 Al-20wt%Si-5wt%Fe 합금분말 압출재의 강도에 관한 연구)

  • 김택수
    • Journal of Powder Materials
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    • v.1 no.1
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    • pp.66-71
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    • 1994
  • Optical microstructures and mechanical properties of Na gas atomized Al-20Si-5Fe alloying powder and its hot extrudates were studied on 3 different types of powder size distribution. This powder showed the size distribution of 10~210 $\mu\textrm{m}$. Also the microstructures of $\alpha$-Al, primary and eutectic Si and needle shaped intermetallic compounds were observed by optical microscope. These needle shaped intermetallic compounds were identified as ${\delta}Al_4FeSi_2$- by XRD and EDX analysis. The ultimate tensile strength(UTS) of these alloy extrudates was increased from 324 to 390 MPa with decreasing powder size range from 120~210 $\mu\textrm{m}$ to 10~64 $\mu\textrm{m}$. A value of Micro-vic-kers hardness was simillar to the result of UTS. These extrudates showed better wear resistance than those of Al-20Si-2X(X : Ni, Cr, Zr), although they are insensitive to the size distribution. These results indicate that the presentation of ${\delta}Al_4FeSi_2$ intermetallic compounds contributed to the wear resistance improvement.

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The Effect of Pine (pinus densiflora) Needle Extracts on Blood Flow and Serum Lipid Improvement (적송잎 추출물의 혈행 및 지질개선 효과)

  • Kang, Sung-Rim;Kim, Young-Kyoung;Kim, Sung-Gu;Lee, Sang-Hyeon;Kim, Mi-Hyang
    • Journal of Life Science
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    • v.19 no.4
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    • pp.508-513
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    • 2009
  • Pine needles have long been used as a traditional health-promoting medicinal food in Korea. To investigate the effects of pine (pinus densiflora) needle extracts on blood flow and serum lipid improvement were assessed in vivo. 8 week-old Sprague Dawley strain rats were divided into four groups of seven rats each; CON, 0.5% CHOL, HOT water and Sub-supercritical group. Serum total cholesterol and triglyceride contents were lower in the CON group than the 0.5% CHOL group. Three weeks of feeding hot water and sub-supercritical extract resulted in a decrease in serum triglyceride and total cholesterol level. The level of HDL-cholesterol in the 0.5% CHOL group was significantly (p<0.05) reduced compared to the CON group, but it had a tendency to increase with pine needle extract supplementation. Blood passage time of the pine needle extracts supplemented group was higher than the 0.5% CHOL group. Microscopic observation showed that whole blood passed smoothly through the micro channels in pine needle extracts supplemented groups. The platelet aggregation ability of the groups treated with pine needle extracts was less than that of the 0.5% CHOL group. All these results suggest that pine needle extracts might improve blood homeostasis mediated via antiplatelet activities.

Diagnostic Accuracy of Ultrasonography in Differentiating Benign and Malignant Thyroid Nodules Using Fine Needle Aspiration Cytology as the Reference Standard

  • Alam, Tariq;Khattak, Yasir Jamil;Beg, Madiha;Raouf, Abdul;Azeemuddin, Muhammad;Khan, Asif Alam
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.10039-10043
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    • 2014
  • Background: In Pakistan thyroid cancer is responsible for 1.2% cases of all malignant tumors. Ultrasonography (US) is helpful in detecting cancerous thyroid nodules on basis of different features like echogenicity, margins, microcalcifications, size, shape and abnormal neck lymph nodes. We therefore aimed to calculate diagnostic accuracy of ultrasound in detection of carcinoma in thyroid nodules taking fine needle aspiration cytology as the reference standard. Materials and Methods: A cross-sectional analytical study was designed to prospectively collect data from December 2010 till December 2012 from the Department of Radiology in Aga Khan University Hospital, Karachi, Pakistan. A total of 100 patients of both genders were enrolled after informed consent via applying non-probability consecutive sampling technique. Patients referred to Radiology department of Aga Khan University to perform thyroid ultrasound followed by fine-needle aspiration cytology of thyroid nodules were included. They were excluded if proven for thyroid malignancy or if their US or FNAC was conducted outside our institution. Results: The subjects comprised 76 (76%) females and 24 males. Mean age was $41.8{\pm}SD$ 12.3 years. Sensitivity and specificity with 95%CI of ultrasound in differentiating malignant thyroid nodule from benign thyroid nodule calculated to be 91.7% (95%CI, 0.72-0.98) and 78.94% (0.68-0.87) respectively. Reported positive predictive value and negative PV were 57.9% (0.41-0.73) and 96.8% (0.88-0.99) and overall accuracy was 82%. Likelihood ratio (LR) positive was computed to be 4.3 and LR negative was 0.1. Conclusions: Ultrasonography has a high diagnostic accuracy in detecting malignancy in thyroid nodules on the basis of features like echogenicity, margins, micro calcifications and shape.

A Study on Nozzle Flow and Spray Characteristics of Piezo Injector for Next Generation High Response Injection (차세대 고응답 분사용 피에조 인젝터의 노즐유동 및 분무특성에 관한 연구)

  • Lee Jin-Wook;Min Kyoung-Doug
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.30 no.6 s.249
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    • pp.553-559
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    • 2006
  • Most diesel injector, which is currently used in high-pressure common rail fuel injection system of diesel engine, is driven by the solenoid coil energy for its needle movement. The main disadvantage of this solenoid-driven injector is a high power consumption, high power loss through solenoid coil and relatively fixed needle response's problem. In this study, a prototype piezo-driven injector, as a new injector mechanism driven by piezoelectric energy based on the concept of inverse piezo-electric effect, has been designed and fabricated to know the effect of piezo-driven injection processes on the diesel spray structure and internal nozzle flow. Firstly we investigated the spray characteristics in a constant volume chamber pressurized by nitrogen gas using the back diffusion light illumination method for high-speed temporal photography and also analyzed the inside nozzle flow by a fully transient simulation with cavitation model using VOF(volume of fraction) method. The numerical calculation has been performed to simulate the cavitating flow of 3-dimensional real size single hole nozzle along the injection duration. Results were compared between a conventional solenoid-driven injector and piezo-driven injector, both equipped with the same micro-sac multi-hole injection nozzle. The experimental results show that the piezo-driven injector has short injection delay and a faster spray development and produces higher injection velocity than the solenoid-driven injector. And the predicted simulation results with the degree of cavitation's generation inside nozzle for faster needle response In a piezo-driven injector were reflected to spray development in agreement with the experimental spray images.

Bioinspired Metal Surfaces by Plasma Treatment

  • Yu, Ui-Seon;Go, Tae-Jun;O, Gyu-Hwan;Mun, Myeong-Un
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.97-97
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    • 2013
  • The exterior structures of natural organisms have continuously evolved by controlling wettability, such as the Namib Desert beetle, whose back has hydrophilic/hydrophobic contrast for water harvesting by mist condensation in dry desert environments, and some plant leaves that have hierarchical micro/nanostructures to collect or repel liquid water. In this work, we have provided a method for wettability contrast on metals by both nano-flake or needle patterns and tuning of the surface energy. Metals including steel alloys and aluminum were provided with hierarchical micro/nanostructures of metaloxides induced by fluorination and a subsequent catalytic reaction of fluorine ions on metal surfaces in water with various ranges from room to boiling temperature of water. Then, a hydrophobic material was deposited on the structured surfaces, rendering superhydrophobicity. Plasma oxidization induces the formation of superhydrophilic surfaces on selective regions surrounded by superhydrophobic surfaces. We show that wettability contrast surfaces align liquid water within patterned hydrophilic regions during the condensation process. Furthermore, this method could have a greater potential to align other liquids or living cells.

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Semi-active Vibration Drug Delivery Device Design using a Micro-needle Fabrication and Array (미세바늘제작 및 배열을 이용한 반 능동형 가진 약물주입기구 설계)

  • Sung, Yeon-wook;Park, Jean Ho;Lee, Hye-Jin
    • Journal of Institute of Convergence Technology
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    • v.1 no.1
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    • pp.48-51
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    • 2011
  • Transdermal drug delivery device is a method of drug delivery through the skin. Skin has a very large area, so it is attractive route to drug delivery. When drug delivery through the skin, microneedle has a advantage that painless, constant drug deliver and penetration efficient; nevertheless the cost is expensive because fabrication process need a particular equipment and not suitable in mass production. This study shows microneedle fabrication process using convergence of general MEMS process and dicing process that can make 3-D sharp microneedle tip and this fabrication process suitable for mass production.

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Particle Acceleration via Laser Ablation

  • Choi, Ji-Hee;Yoh, Jai-Ick
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2008.03a
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    • pp.566-569
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    • 2008
  • Recently, the biolistic process is emerging as an effective needle-free drug delivery technique to transfer adequate concentrations of pharmacologic agents to soft living tissues with minimum side effects. We have started developing an effective method for delivering drug coated particles using laser ablation. A thin metal foil with deposited micro-particles on one side is irradiated with laser beam on the opposite side so that a shock wave is generated. This shock wave travels through the foil and is reflected, which causes and instantaneous deformation of the foil. Due to such a sudden deformation, the micro-particles are ejected at a very high speed. Here we present the experimental results of direct and confined laser ablation, which correspond to the initial stage of the whole experiment.

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