• Title/Summary/Keyword: Micro Injection

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A study on the process optimization of injection molding for replicability enhancement of micro channel (미세채널 전사성 향상을 위한 사출성형 공정최적화 기초연구)

  • Go, Young-Bae;Kim, Jong-Sun;Yu, Jae-Won;Min, In-Gi;Kim, Jong-Duck;Yoon, Kyung-Hwan;Hwang, Cheul-Jin
    • Design & Manufacturing
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    • v.2 no.1
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    • pp.45-50
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    • 2008
  • Micro channel is to fabricate desired pattern on the polymer substrate by pressing the patterned mold against the substrate which is heated above the glass transition temperature, and it is a high throughput fabrication method for bio chip, optical microstructure, etc. due to the simultaneous large area patterning. However, the bad pattern fidelity in large area patterning is one of the obstacles to applying the hot embossing technology for mass production. In the present study, stamper of cross channel with width $100{\mu}m$ and height $50{\mu}m$ was manufactured using UV-LiGA process. Micro channel was manufactured using stamper manufactured in this study. Also replicability appliance was evaluated for micro channel and factors affected replicability were investigated using Taguchi method.

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The development of LIGA & MEMS precess for fabricating micro CPL (Micro CPL 제작을 위한 LIGA & MEMS 공정개발)

  • Cho, Jin-Woo;Jung, Suk-Won;Park, Jun-Sik;Park, Soon-Sup
    • Proceedings of the KIEE Conference
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    • 2002.07c
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    • pp.1976-1978
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    • 2002
  • micro CPL 제작을 위한 LICA 및 MEMS 공정을 개발하였으며 양산화를 위한 새로운 방법으로 ${\mu}$MIM(micro Metal Injection Molding) 기술을 제안하였다. 먼저 LIGA 기술을 이용하여 Cu 도금 구조물로 이루어진 micro CPL 구조물을 제작하였다. 각각 상판과 하판 구조물로 나누어 제작하였으며 상, 하판 Cu 구조물을 brazing 방법을 이용하여 접합하였다. 또한 micro CPL 내부에서 일어나는 냉매의 흐름 및 상변화(liquid ${\leftrightarrow}$ vapor) 거동을 관찰할 수 있는 새로운 개념의 Si/glass 투명 micro CPL을 제작하였다. 상기 공정을 이용하여 냉각 능력이 10w/$cm^2$ 이상인 micro CPL을 제작하였다. 상기 연구 결과를 바탕으로 양산화를 위한 새로운 정밀복제기술인 ${\mu}$MIM(Micro Metal Injection Molding) 공정을 개발하였다. LISA 공정으로 제작된 정밀 금형을 core금형으로 사용하였고 $1{\mu}m$ 이하의 W-Cu(10%) powder와 binder가 혼합된 흔합분말을 이용하여 micro channel 구조물(선폭 $100{\mu}m$)의 성형 복제에 성공함으로서 양산화를 향한 기반기술을 확립하였다.

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Application of biodegradable metal based drug delivery carrier on Foot and Mouth Disease vaccination in pigs (돼지에서 생체 분해 금속성 전달체를 활용한 구제역 백신의 적용 연구)

  • Cho, Ara;Oh, Sang-Ik;Choe, Changyong;Jung, Young-Hun;Do, Yoon Jung;Kim, Suhee;Choo, Hyun Wook;Gu, Jong Su;Chung, Woo-Jin;Cho, Sung Youn;Yoo, Jae Gyu
    • Korean Journal of Veterinary Service
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    • v.43 no.3
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    • pp.129-137
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    • 2020
  • In this study, we applied biodegradable drug delivery carries (BDDC) for food-and-mouth (FMD) vaccination. After FMD vaccination using BDDC, we estimated the percentage inhibition (PI) of antibody, decomposed patterns, and histopathologic features of BDDC. PI of antibody was higher than 50 at two weeks after injection and sustained positive PI until 10 weeks after injection. BBDC injection group showed significantly an increased pattern of blood monocyte at two and three weeks after injection. According to the Micro CT, micro-cracks were observed at two weeks after injection and the morphology of BDDC was lost at four weeks after injection. For histopathological examination, acute inflammation with neutrophil infiltration and micro-metallic residues were observed around BDDC until four weeks after injection and inflammatory responses gradually decreased at 10 weeks. Based on our experiment, BDDC is considered as an alternative way to vaccine injection for veterinary applications. Our study can be used as basic data for the drug delivery system using biodegradable metals in the future.

Design and Fabrication of a Microflow Rate Controller for Medical Injection (주사용 미세유량 조절기 설계와 제작)

  • Kim, Byoung-Jae;Lee, Sang-Bin;Shin, Bo-Sung;Sung, Hyung-Jin
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.2
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    • pp.154-159
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    • 2004
  • A new microflow rate controller for medical injection was developed and evaluated. The flow rate was controlled by changing the friction depth as well as the friction length of the micro-channel. A precise micro-fabrication of the micro-channel was requested for an accurate flow control. The friction depth was inversely proportional to the friction length, which gives a linear flow control to the channel length. The channel groove was fabricated with a plastic material. A rubber containing silicone oil was covered over the groove, which satisfies both lubrication and leakage prevention. The flow controller was validated by performing the numerical simulation and experiment. A good agreement was shown between computation and experiment.

Net-shape Manufacturing of Micro Porous Metal Components by Powder Injection Molding

  • Nishiyabu, Kazuaki;Matsuzaki, Satoru;Tanaka, Shigeo
    • Proceedings of the Korean Powder Metallurgy Institute Conference
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    • 2006.09a
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    • pp.93-94
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    • 2006
  • A novel production method for porous metal components has been developed by applying powder space holder (PSH) method to metal powder injection molding (MIM) process. The PSH-MIM method has an industrial competitive advantage that is capable of net-shape manufacturing the micro-sized porous metal products with complicated shapes and controlled porosity and pore size. In this study, the small impeller with homogeneous micro-porous structure was manufactured by the PSH-MIM method. The effects of combinations in size and fraction of PMMA particle on dimensional tolerance and variation of sintered porous specimens were investigated. It was concluded that the PSH-MIM method could manufacture commercially microporous metal components with high dimensional accuracy.

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Put English Title Here (금형온도에 의한 미세패턴 성형 특성에 관한 연구)

  • Kim, Chang-Wan;Yoo, Yeong-Eun;Kwon, Ki-Hwan;Je, Tae-Jin;Choi, Doo-Sun
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.1129-1131
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    • 2008
  • We injection molded a plate with micro surface features including micro prizms & micro channels patterns on its surface and investigated the replication of the micro features depending on the mold temperature which is one of typical process parameters. The size of the patterns were 8um, 10um, 15um of prizm features & 15um, 30um, 45um of channel features. The size of the plate is about $400mm{\times}400mm$ and the thickness is 1mm of plate. the repliction of the mucro features turned out to depend on the mold temperature and also the location on the plate. The pressure and the feature of the melt in the cavity were also measured in real-time for the investigation on the micro feature replication.

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A study on fabrication of a micro patterned LGP (미세 패턴 응용 도광판 제작에 관한 연구)

  • Yoo Y.E.;Kim T.H.;Kim S.G.;Seo Y.H.;Je T.J.;Choi D.S.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.533-534
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    • 2006
  • Micro pyramid pattern and its array are designed to enhance the brightness and its uniformity of LGP which is one of key parts in LCD. The designed micro pyramid patterns are fabricated on a Si-wafer first through MEMS process and then a Ni-stamper is electro-plated from the Si pattern master. Adopting the fabricated Ni-stamper, LGPs are injection molded at different mold temperatures and the fidelity of the pattern replication is estimated for each molding conditions and pattern locations. The replicated patterns are found to have some defect such as local short shot or micro weld line which are believed to have negative effect on the performance of the LGP.

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In Vitro Test of a Micro Syringe Fabricated for the Intravascular Injection (초소형 주사 시스템의 모의 혈관 내에서의 작동 시험)

  • Kim, Geun-Young;Sim, Woo-Young;Lee, Sang-Woo;Yang, Sang-Sik;Chang, Jun-Keun;Lee, Seung-Ki
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.50 no.6
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    • pp.307-313
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    • 2001
  • A micro syringe which can be attached to the end of a micro intravascular endoscope for drug injection is fabricated and its characteristic is tested. The syringe consists of a drug chamber and an actuator chamber which are separated by a silicone rubber membrane. The drug chamber is filled with liquid drug by the membrance actuation caused by the vaporization and condensation of the working liquid in the actuator chamber. The liquid drug is ejected by the electrolysis of the working liquid. The membrane deflection by each actuation method has been measured. The liquid ejection image has been captured during the electrolysis of the electrolyte. Also, the successful operation of the micro syringe under the normal blood pressure was verified.

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