• 대한한의학회지
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• 제39권1호
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• pp.13-21
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• 2018

Objectives: The objective of this study is to develop the diagnostic tool to distinguish between cold syndrome (CS) and heat syndrome (HS). Methods: A total of 1,753 subjects were divided into three groups, those are CS group, intemediate group, and HS group, by the mean and standard deviation of the cold heat syndrome differentiation score using 7 point scale consisting of 9 items. Demographic characteristics, diseases history, health status, Mibyeong, syndrome differentiation were analyzed. Results: CS is characterized by women, elderly, and low body mass index. CS has a history of thyroid disease, cataract, depression, osteoporosis, and HS has a history of prostatomegaly. CS receives less social psychosocial stress than HS, and the quality of life associated with health status is lower than HS. CS group has the tendency to be tired, painful, sleepless, dyspeptic and anxious. Conclusions: CS is a set of symptoms associated with decreased energy metabolism and decreased metabolic function, and is more likely to be unhealthy than HS.

• 한방안이비인후피부과학회지
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• 제29권4호
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• pp.131-141
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• 2016

Objectives : The purpose of this study is to understanding the patients thought of Korean Medical treatment and to suggest an improvement in utilization of Korean Medicine treatment about atopic dermatitis. Methods : We had investigate atopic dermatitis online community by classifying the post by treatment type, feature type of the information and by content to know the patients latest tendency. And then compare the result to understand the patients thought of Korean Medical treatment. Results : Most of the post was experiential information and about 67% of the post was about symptom and treatment. Especially there had lot of interest about there treatment information and self-treatment. By contrast Korean Medical treatment type has lower rate then other type of treatment about symptom and treatment and the information was not specific. This result may influence on utilization of Korean Medical treatment. Conclusions : To solve this problem patients needs easy access to Korean Medical treatment and more information about there treatment.

• 대한한의학회지
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• 제37권3호
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• pp.87-96
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• 2016

Objectives: Through this study, it would be expected to compare the characteristics of medicinal and acupuncture treatment. Method: Ontology DB of traditional Korean medicine has been used comparing medicinal and acupuncture treatment. Terms of the efficacy and the method of treatment were divided to predicate and object. And two groups were compared through contrasting the frequency of occurrence of significant words. Results: Predicates utilized more in medicinal treatment are the character ryeom[斂], go[固], pa[破], nae[內], and tu [透]. Predicates utilized more in acupuncture treatment are the character so[疏], jo[調], and seo[舒]. Object utilized more in acupuncture treatment is the character gi[氣]. Object utilized more in medicinal treatment is the character jeong[精]. Conclusions: In terms about the efficacy of acupuncture, there are many expressions associated with Qi[氣]. But expressions associated with Jing[精] are rare compare to medicinal treatment. There is a difference in language that represents the efficacy between medicinal and acupuncture treatment. In addition, there are some terms about efficacy that are not shared with each other due to the differences in disease treatment and the different branches of the two theories.

• 사상체질의학회지
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• 제27권2호
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• pp.211-221
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• 2015

Objectives The aim of this study is to develop a Korea Sasang Constitutional Diagnostic Questionnaire (KS-15) with practicality and validity. Methods The data of body shape, temperament and symptoms were collected from 11 nationwide multi-centers in Korean Medical Clinics between Nov. 2009 to Aug. 2012. KS-15 algorithm was developed through Multinomial Logistic Regression and was applied for test group to verify it's classificatory function. Results The weight value of variables of KS-15 were different between male and female. The concordance of KS-15 with the expert in training group was 58.34% (72.8% in Tae-eumin, 54.8% in Soeumin, and 44.1% in Soyangin). The concordance of KS-15 with the expert in test group was 63.1% (63% in Tae-eumin, 83.3% in Soeumin, and 51.9% in Soyangin). Conclusions KS-15 seems to have suitable implement with practicality and validity. Further study is necessary to verify it accuracy and cut-off.

• 사상체질의학회지
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• 제27권2호
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• pp.222-230
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• 2015

Objectives The purpose of this study is to design a research to find clinical factors involved in the decision-making process for determining the constitutional prescription based on prospective clinical data. Methods We have created a draft of the case report form. Therefore, seven constitutional experts was interviewed for additional items to be important used to determine the constitutional prescription in clinic. Interviews were done from December 2012 to March 2014, experts per person 2-3 times, took time of about 120 minutes per interview. Since then, we developed the final case report form through the expert meeting. At the same time, the developing the electronic case report form (eCRF) and the protocol to collect constitutional treatment cases was also discussed. Results & Conclusions The items of the case report form were subject general, lifestyle, health measurement, record of expert, prescription and evaluation after medication. The part of the clinical symptoms of the record of expert allowed to be recorded in the 5-point scale for the collection of quantitative data as much as possible. Assuming a re-visit of the patient, if necessary, twice the recording were to be possible. At the same time, the eCRF and the protocol to collect constitutional treatment cases were also developed. In this study, it will be able to more objectively standardize the medical decision making process that the experts of constitutional prescription decision. As a result, it will be possible to provide the standardized constitutional medical services.

• 동의생리병리학회지
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• 제35권6호
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• pp.267-273
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• 2021

Mibyeong (sub-health) is a concept that represents the sub-health in traditional East Asian medicine. Assuming that the nose sizes and shapes are related to respiratory function, in this study, we hypothesized that the nose size and shape features are related to the self-rated health (SRH) level and self-rated Mibyeong severity, and aimed to assess this relationship using a fully automated image analysis system. The nose size features were evaluated from the frontal and profile face images of 810 participants. The nose size features consisted of five length features, one area feature, and one volume feature. The level of SRH and the Mibyeong severity were determined using a questionnaire. The normalized nasal height was negatively associated with the self-rated health score (SRHS) (partial ρ = -0.125, p = 3.53E-04) and the Mibyeong score (MBS) (partial ρ = -.172, p = 9.38E-07), even after adjustment for sex, age, and body mass index. The normalized nasal volume (ρ = -.105, p = 0.003), the normalized nasal tip protrusion length (ρ = -.087, p = 0.014), and the normalized nares width (ρ = -.086, p = .015) showed significant correlation with the SRHS. The normalized nasal area (ρ = -.118, p = 0.001), the normalized nasal volume (ρ = -.107, p = .002) showed significant correlation with the MBS. The wider, longer, and larger the nose, the lower the SRHS and MBS, indicating that health status can be estimated based on the size and shape features of the nose.

• 대한예방한의학회지
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• 제20권3호
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• pp.67-74
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• 2016

Objectives : The purpose of this study was to analyze the relationship between the Cold-pattern and the quantitative index through the results of an anthropometric method and Bio Impedance Analysis (BIA) of the Haenyeo living in Jeju island. Furthermore, we will examine the effect of Cold-pattern on the quality of life. Methods : BIA indices were acquired directly from Inbody770 and questionnaires were collected by Gallup Korea professional surveyor through face to face interviews. Binary regression analysis and linear regression analysis were used to examine the association between collected data. Results : Total of 175 of people were participated in this study. First, we examined the difference of the indicators in the Cold-pattern group and the non-Cold pattern group by the average comparison of the anthropometry and BIA indices. Most of the non-Cold pattern group showed high quality of life, BIA and anthropometry. In the relationship between Cold-pattern and anthropometry and BIA indices, BMI and PA indices were found to affect the Cold-pattern on a group basis. As the BMI increased by $1kg/m^2$, probability of not being non-Cold pattern was 1.13 times. and as the PA increased by $1^{\circ}$, probability of not being non-Cold pattern was 2.4 times. In the case of EQ5D value, the quality of life of ${\beta}$ was increased by 0.08 in non-Cold pattern (p <.05), EQ5D VAS of ${\beta}$ was also increased by 10.05 (p <.05). Conclusions : This study showed that BMI and PA could be used as a clinical index to evaluate the Cold-pattern as a clinical indicator, and there is a difference in quality of life according to Cold-pattern.

• 대한한의학회지
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• 제41권2호
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• pp.58-79
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• 2020

Objectives: The purpose of this study is to predict the weight loss by applying machine learning using real-world clinical data from overweight and obese adults on weight loss program in 4 Korean Medicine obesity clinics. Methods: From January, 2017 to May, 2019, we collected data from overweight and obese adults (BMI≥23 kg/m2) who registered for a 3-month Gamitaeeumjowi-tang prescription program. Predictive analysis was conducted at the time of three prescriptions, and the expected reduced rate and reduced weight at the next order of prescription were predicted as binary classification (classification benchmark: highest quartile, median, lowest quartile). For the median, further analysis was conducted after using the variable selection method. The data set for each analysis was 25,988 in the first, 6,304 in the second, and 833 in the third. 5-fold cross validation was used to prevent overfitting. Results: Prediction accuracy was increased from 1^st to 2^nd and 3^rd analysis. After selecting the variables based on the median, artificial neural network showed the highest accuracy in 1^st (54.69%), 2^nd (73.52%), and 3^rd (81.88%) prediction analysis based on reduced rate. The prediction performance was additionally confirmed through AUC, Random Forest showed the highest in 1^st (0.640), 2^nd (0.816), and 3^rd (0.939) prediction analysis based on reduced weight. Conclusions: The prediction of weight loss by applying machine learning showed that the accuracy was improved by using the initial weight loss information. There is a possibility that it can be used to screen patients who need intensive intervention when expected weight loss is low.

• 한국콘텐츠학회논문지
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• 제22권8호
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• pp.671-680
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• 2022

본 연구의 목적은 한의학 기반 건강상태 및 진단 분류 도구인 미병과 한열설문의 웹 기반과 종이 기반 간의 일치도를 평가하는 것이다. 일반인 72명을 대상으로 웹 기반 조사를 먼저 시행하고, 시간 간격을 두고 종이기반 설문을 진행하였다. 웹과 종이 기반 조사 방법 간의 동등성은 급내상관계수(Intraclass Correlation Coefficient, ICC)와 Bland-Altman 방법으로 설문 점수 간의 일치도를 평가하였다. 미병설문은 웹과 종이 조사 간에 높은 신뢰도를 보였고(ICC=0.95, 95% CI 0.92 - 0.97), 한열설문의 한증(ICC=0.98, 95% CI 0.96 - 0.99)과 열증(ICC=0.9, 95% CI 0.83 - 0.93) 모두 우수한 신뢰도를 나타냈다. 두 조사 방법 간의 평균 점수 차이는 미병설문이 -0.25점이고, 한열설문의 한증 -0.17점, 열증 0.11점으로 유사한 일치 양상을 나타냈다. 대상자의 84%가 웹 기반에 긍정적인 만족도를 보였고, 80%가 웹 조사를 선호하였다. 본 연구에서 미병설문과 한열설문의 웹 조사 방법 간의 신뢰도와 실행 가능성을 확인하였다. 이것은 장기간 걸쳐 진행되는 코호트 연구에서 대상자 추적 관찰에 유용한 도구로 고려된다.

• 대한예방한의학회지
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• 제20권1호
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• pp.65-73
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• 2016

Objectives : In this study, we investigated the trends of cohort project in domestic and overseas, and suggested the necessity of cohort on korean medicine and the direction of research. Methods : The papers which include cohort in the title and published by 2015 were searched using PubMed. In order to study the history of cohort in domestic and overseas, research trend was investigated based on the websites of each cohort projects and traditional medicine searching engine named OASIS. Results : Using PubMed, 42,802 papers were searched. Most of the studies over 50 % of total articles, however, were conducted in these 6 years. Nevertheless, cohort studies are being actively proceed, the korean medicine based on cohort studies are nonexistent. Therefore, further discussion about cohort study on korean medicine is necessary to gather physiological index and clinical index of korean medicine consistently. Conclusions : Systematically constructed cohort on korean medicine would be the foundation which collects information, such as gene information, bio information, dietary habit, life style, and Pattern identification (辨證), and integrates them. The analysis of massive clinical materials could suggest the basis of Prevention and treatment of korean medicine considering the difference between personal.