• Journal of The Korean Society of Grassland and Forage Science
• /
• v.9 no.1
• /
• pp.26-33
• /
• 1989

This pot experiments were conducted to find out the optimal fertilization ratios of the N:S:P anions and K:Ca:Mg cations of major nutrients in an orchardgrass/ladino clover mixed sward. The optimum ratios in equivalent basis were computed by the Homes systematic variations technique. The soil samples were collected from the newly reclaimed soils, which are located on colluvial hilly area with a good consideration for the hilly pasture development. The results were summarized as follows; 1, the optimum fertilization ratios of major nutrients for the high yields by the forage species in a mixed sward were obtained (Table 4 in detail); N:S:P = 3:l: 1 and K:Ca:Mg = 1:l: 1 for grass and grass plus legume, and N:S:P = 1:6:43 and K:Ca:Mg = 1: 3: 1 for legume in general. 2. The yield increases from the systematic variations in this mixed sward were laid in following order; N > P >S-group and K >Mg >Ca-group for grass and grass plus legume, and P >S >N-group and Ca >Mg > K-group for legume. Especially, the yields were greatly increased at the N-group for grass, and at the Pand Ca-groups for legume. 3. Soil pH-value was descreased at the Sgroup, and somewhat increased at the Ca- and Mg-groups. The content of available $P_2O_5$, CEC and base saturation were greatest with the Ca-group. 4. At the N-group, the N-contents were highest and the P-contents were lowest in grass and grass plus legume, which resulted in the highest Ca/P ratio of 2.15 among the anion groups. Whereas the highest Ca/P ratio of 9.20 in legume was obtained at the Ca-group. Legume showed in general higher Ca/P ratio and lower K/(Ca+Mg) ratio than these in grass. 5 . There were differences in the effects of systematic variations of major nutrients on the dry matter yields and the mineral yields. The optimum fertilization ratios of anions and cations for the high mineral yields were obtained (Table E), which showed differences comparing with the ratios for the high dry matter yields. The antagonis between the cations K and Mg was known from the point of mineral yields of mixed forages.

• The Journal of Internal Korean Medicine
• /
• v.23 no.1
• /
• pp.123-131
• /
• 2002

Objective : It is well known that modern chemotherapy against cancer has side effects to a living body, especially hemopoietic and immunologial disfunctions. However, there are no effective ways to reduce them. Recently, traditional Korean herb medicine has been reported to have some biological modifying responses. Therefore, we hypothesized that additional application of herb medicine during chemotherapy is more effective to reduce its side effects. While we were studying the effects, we have observed the inhibitory effect of Soamgudamikgitang on formation of side effects derived from Cyclophosphamide, it has been used in clinical practice at Kyung Hee Medical Center. Methods : We injected 200mg/kg of Cyclophosphamide, one time, to an experimental group, consisting of ten mice. We divided them into eight groups: normal, CPX, SAKT 2mg, SAKT 10mg, SAKT 50mg, SAKT 2mg, CPX, SAKT 10mg+CPX, SAKT 50mg+CPX. We injected Soamgudamikgitang seven days, five days, three days, and one day before we injected CPX. One day, three days, and five days after CPX injection, we injected Soamgudamikgitang again and then killed all the mice. The parameters determined in this experiment were daily body weight liver and spleen weight, RBC, WBC, and platelet for hemopoietic dysfunction and AST, ALT for hepatotoxicity, BUN, creatine for renal toxcity, lymphocyte proliferation activity and lymphocyte subsets for immunological toxcity. Results : We have found that Soamgudamikgitang has inhibitory effects on the formation of Cyclophosphamide's side effects. Significant differences between the group, which contained Cyclophosphamide, and the other group, which contains Cyclophosphamide and 2, 10, 50mg of Soamgudamikgitang respectively were observed. Platelets(2mg of Soamgudamikgitang, p<0.05 ;10mg, p<0.01 ;50mg, p<0.001), liver weight(50mg, p<0.01), spleen weight(10mg, p<0.05), AST(all groups, p<0.01), ALT(2mg, p<0.01 ;10mg, p<0.05 ;50mg, p<0.01), BUN(2mg, p<0.01 ;50mg, p<0.05). Although immunological in both lymphocyte proliferation and its subsets were not observed, which shows that Soamgudamikgitang has a strong effect on T cell activities. Conclusions : From the above results, we can expect that the combined therapy of Soamgudamikgitang and Cyclophosphamide is more effective for treating cancer patients.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.36 no.2
• /
• pp.180-185
• /
• 2007

This study demonstrates that pork cholesterol levels are reduced in fattening stage swine fed $\beta-cyclodextrin({\beta}-cyclodextrin)$. The study subjects were 120 swine fed their respective chow diets containing 0, 5, 7, or 10% $\beta$-cyclodextrin for 35 consecutive days. Plasma total lipids, triglyceride and total cholesterol of the $\beta$-cyclodextrin treated group were significantly lower than those of the control group (p<0.05). The levels of plasma lipid were significantly decreased by 63.22 mg, 73.98 mg, and 82.12 mg in the fattening swine group fed $\beta$-cyclodextrin at 5%, 7%, and 10%, respectively, compared to those in the control group (p<0.05). When 5, 7, and 10% $\beta$-cyclodextrin was administered to fattening swine, the triacylglyceride levels were decreased by 56.24 mg, 55.48 mg, and 60.02 mg, and total cholesterol concentration was reduced by 25.05 mg, 27.17 mg, and 30.19 mg, respectively, compared to those in the control group (p<0.05). Excretion of total steroid significantly (p<0.05) increased with the increasing amount of $\beta$-cyclodextrin supplementation. The cholesterol levels of swine back fat, belly, loin, and ham were significantly decreased with increasing $\beta$-cyclodextrin supplementation (p<0.05). The pork cholesterol was significantly (p<0.05) reduced by 15.31% in the $\beta$-cyclodextrin treated group, compared to that of the control group. These results suggest that feeding $\beta$-cyclodextrin to fattening swine may produce novel functional pork with low cholesterol levels.

• Applied Chemistry for Engineering
• /
• v.30 no.5
• /
• pp.580-585
• /
• 2019

In this study, we synthesized amine-functionalized magnesium-phyllosilicates (AF-MgP) with an octahedral and tetrahedral structure using (3-aminopropyl)triethoxysilane. The synthesis of AF-MgP, surface functionalization of amine and 1 : 2 ratio of the octahedral and tetrahedral structure were confirmed by FT-IR and XRD analysis. In addition, it was confirmed that AF-MgP was absorbed evenly on the surface of cotton fibers and coated on the cotton fibers from HR-SEM and EDX analysis. The antimicrobial activity test of cotton fibers according to KS confirmed that cotton fibers coated with AF-MgP particles show an enhanced antimicrobial activity against cutaneous microorganisms. Our results suggest that AF-MgP is not only applied as a functional nanomaterial that gives the cotton fiber antimicrobiality, but also can be used in the field of cosmetic and biomedical materials.

• Korean Journal of Soil Science and Fertilizer
• /
• v.24 no.4
• /
• pp.248-253
• /
• 1991

This study examines the effect of submergence on transformations of inorganic phosphorus and the relation between fractions of inorganic phosphorus and adsorbed phosphorus in Gangseo (paddy soil), Yesan (non-cultivated soil), and Jungdong soil (upland soil). The soils were submerged with glucose sol'n at $28^{\circ}C$ for 17 days. After, the soils were incubated with phosphate solution at $25^{\circ}C$ for 24 hours. The seguential fractionation of inorganic phosphorus and of iron were conducted to investigate transformations of them. Results obtained are as follows; 1. By submergence, Bray I-P were decreased from 53mgP/kg to 48mgP/kg in Gangseo, from 3mgP/kg to 1mgP/kg in Yesan, and from 120mgP/kg to 56mgP/kg in Jungdong soil. 2. $NH_4F$ extractable P was dominant fraction of adsorbed P. It was transformed into NaOH extractable P by submergence in Jungdong soil. 3. Dithionite-citrate-bicarbonate extractable iron (crystalline Fe) was transformed to oxalate extractable iron (amorphous Fe) by submergence in Yesan soil.

• Korean Journal of Weed Science
• /
• v.8 no.3
• /
• pp.283-290
• /
• 1988

This study was conducted to clarify the identification of phytotoxic compounds from 5 upland weeds which had been collected at their maturity age in the field of Kyungpook province, Korea. 5 weed species including Stellaria aquatica strongly inhibited the lettuce seed germination. These 5 species were Amaranthus lividus, Stellaria aquatica, Achyranthes japonica, Polygonum perfoliata and Galinsoga ciliata. the degree of inhibitory effects according to various solvent extracts such as ethanol, aceton, chloroform and ether was different as species. In total phenol and diphenol content G. ciliata had largest amount of total phenol with 2.75mg/g, P. perfoliata 1.8mg/g, S. aquatica 1.7mg/g, A. lividus 1.28mg/g, A. japonica 1.27mg/g respectively. A. lividus had much amount of p-cresol, hydroquinone, ferulic, caffeic, p-cl-benzoic and p-coumaric in order. S. aquatica, A. japonica, P. perfoliata and G. ciliata had a large quantity of ferulic, caffeic, 7-OH-coumarin and protocatechuic acids in common. The amount of fatty acids was existed 8.49mg/g in S. aquatica, 7.14mg/g in A. japonica, 7.10mg/g in G. ciliata, 5.49mg/g in P. perfoliata and 4.2mg/g in A. lividus respectively. Most of 4 weeds except G. ciliata had much oxalic acid to the extent of 14-22mg/g. however it appeared that G. ciliata had much quantity of feruic and citric acids.

• Journal of Korean Society of Environmental Engineers
• /
• v.35 no.1
• /
• pp.17-22
• /
• 2013

In this study, a pH control method by carbon dioxide ($CO_2$) was applied to coagulation process in water treatment plant (WTP) to investigate the coagulation efficiency and residual dissolved aluminum when high pH raw water is flowing into the plant during algal blooming. Existing coagulant dose (1 mg/L in raw water) resulted in the pH reduction of 0.0384 by LAS, 0.0254 by PAC, 0.0201 by A-PAC, and 0.0135 by PACS2, respectively. And then the concentration of dissolved aluminum was 0.02 mg/L at pH 7.44, 0.07 mg/L at pH 7.96, 0.12 mg/L at pH 8.16, 0.39 mg/L at pH 8.38 showing the concentration increase with pH in the coagulation process. It was noteworthy that rapid increase was observed at pH above 8.0 next the rapid mixing. Therefore it is necessarily required to control pH below 7.8 in the coagulation process in order to meet drinking water quality standard of aluminum for high pH raw water into WTP, $CO_2$ injection could control pH successfully at about 7.3 even for the raw water of high pH above 8.0. In addition it was found that the pH control by $CO_2$ injection was significantly effective for coagulation in terms of turbidity removal, coagulant dosage, and residual dissolved aluminum concentration.

• Tuberculosis and Respiratory Diseases
• /
• v.44 no.3
• /
• pp.479-492
• /
• 1997

Background : Isoniazid(INH) and rifampicin(RFP) are potent antituberculous drugs which have made tuberculous disease become decreasing. In Korea, prescribed doses of INH and RFP have been different from those recommended by American Thoracic Society. In fact they were determined by clinical experience rather than by scientific basis. Even there has been. few reports about pharmacokintic parameters of INH and RFP in healthy Koreans. Method : Oral pharmacokinetics of INH were studied in 22 healthy native Koreans after administration of 300 mg and 400mg of INH to each same person successively at least 2 weeks apart. After an overnight fast, subjects received medication and blood samples were drawn at scheduled times over a 24-hour period. Urine collection was also done for 24 hours. Pharmacokinetics of RFP were studied in 20 subjects in a same fashion with 450mg and 600mg of RFP. Plasma and urinary concentrations of INH and RFP were determined by high-performance liquid chromatography(HPLC). Results : Time to reach peak serum concentration (Tmax) of INH was $1.05{\pm}0.34\;hrs$ at 300mg dose and $0.98{\pm}0.59\;hrs$ at 400mg dose. Half-life was $2.49{\pm}0.88\;hrs$ and $2.80{\pm}0.75\;hrs$, respectively. They were not different significantly(p > 0.05). Peak serum concentration(Cmax) after administration of 400mg of INH was $7.14{\pm}1.95mcg/mL$ which was significantly higher than Cmax ($4.37{\pm}1.28mcg/mL$) by 300mg of INH(p < 0.01). Total clearance(CLtot) of INH at 300mg dose was $26.76{\pm}11.80mL/hr$. At 400mg dose it was $21.09{\pm}8.31mL/hr$ which was significantly lower(p < 0.01) than by 300mg dose. While renal clearance(CLr) was not different among two groups, nonrenal clearance(CLnr) at 400mg dose ($18.18{\pm}8.36mL/hr$) was significantly lower than CLnr ($23.71{\pm}11.52mL/hr$) by 300mg dose(p < 0.01). Tmax of RFP was $1.11{\pm}0.41\;hrs$ at 450mg dose and $1.15{\pm}0.43\;hrs$ at 600mg dose. Half-life was $4.20{\pm}0.73\;hrs$ and $4.95{\pm}2.25\;hrs$, respectively. They were not different significantly(p > 0.05). Cmax after administration of 600mg of RFP was $13.61{\pm}3.43mcg/mL$ which was significantly higher than Cmax($10.12{\pm}2.25mcg/mL$) by 450mg of RFP(p < 0.01). CLtot of RFP at 450mg dose was $7.60{\pm}1.34mL/hr$. At 600mg dose it was $7.05{\pm}1.20mL/hr$ which was significantly lower(p < 0.05) than by 450mg dose. While CLr was not different among two groups, CLnr at 600 mg dose($5.36{\pm}1.20mL/hr$) was significantly lower than CLnr($6.19{\pm}1.56mL/hr$) by 450mg dose(p < 0.01). Conclusion : Considering Cmax and CLnr, 300mg, of INH and 450mg RFP might be sufficient doses for the treatment of tuberculosis in Koreans. But it remains to be clarified in the patients with tuberculosis.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.34 no.5
• /
• pp.521-525
• /
• 2001

Screening tests of different fucoidan fractions from Sporophylls of Undazia pinnatifida, Laminaria religiosa, Hizikia fusiforme and Sagassum fulvellum revealed that the highest biosorptive Pb and Cd uptake fraction was Undaria finnatifida Fr-3.0 prepared by dissolving the precipitated complex (crude fucoidan and cetylpyridinum chloride) with 3.0 M $CaCl_2$ solution, The Pb and Cd uptake by Undaria finnatifida Fr-3.0 was quantitatively evaluated using sorption isotherms and Langmuir sorption model. The Pb and Cd uptake by Undaria finnatifida Fr-3.0 increased with increasing pH values at high equilibrium residual concentration. The highest experimentally observed Pb and Cd uptake value in the sorption isotherm for pH 5.5 were 94 mg/g (at $C_f=164\;mg/L$) and 64 mg/g (at $C_f=197\;mg/L$) respectively, and $q_{max}$ of Pb and Cd calculated by Langmuir sorption model were 178 mg/g and 122 mg/g, respectively. In the low equilibrium concentration range, up to 20 mg/L, the Pb uptake remained unchanged in the presence of Cd, but decreased at higher equilibrium concentration range.

• Applied Microscopy
• /
• v.29 no.3
• /
• pp.281-289
• /
• 1999

The stirred and thixoformed $SiC_p/AZ91HP$ Mg composites are studied on the basis of microstructural analysis using transmission electron microscopy (TEM). The products of interfacial reaction are identified as $Mg_2Si$, MgO and $Mg_{17}Al_{12}$ phases and the crystallized phases are found to be orthorhmbic $Al_6Mn$ and decagonal T phases. It is shown that $Mg_2Si$ and $Mg_{17}Al_{12}$ phases are found at the surface of $SiC_p$ and $Al_6Mn$ is found near interface and crystallized on the matrix. Phase identification is carried out by crystallographic work based on primitive cell volume, zero order Laue zone (ZOLZ) patterns and single convergent beam electron diffraction (CBED) patterns containing higher order Laue zone ring from a nanosized region.