• 한국직업건강간호학회지
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• 제14권2호
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• pp.138-152
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• 2005

Purposes: The purposes of this study are to investigate the definition, components, prevalence, and associated factors of metabolic syndrome and suggest the management strategies for workers. Method: This study was conducted by literature review. Results: Metabolic syndrome by the NCEP-ATP III is the clustering of three or more of five conditions: abdominal obesity, high triglycerides, low levels of HDL cholesterol, high blood pressure, and high glucose(blood sugar). The prevalence of the metabolic syndrome by modified NCEP-ATP III in South Korean workers was about 20 to 25%. Metabolic syndrome is caused by many associated factors, namely, age, family history, socioeconomic status, job strain, shift work, psychosocial distress, bad health behaviprs and so on. Conclusions: To prevent metabolic syndrome at worksites, multifactorial risk factor assessments and preventive approaches are required. Socioeconomic factors such as education, working status should be nationally importantly considered for the health inequality of workers. Occupational health nurse, at first, can start weight control, smoking cessation program. stress management, the improvement of work environment. Next stage, early diagnosis and treatment for metabolic risk group can be performed.

• 한국직업건강간호학회지
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• 제24권1호
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• pp.39-47
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• 2015

Purpose: This study is performed to help manage the metabolic syndrome in work place by identifying the effect on metabolic syndrome with subjects of Korean adult workers. Methods: Using part of data of "The Fourth Korean National Health and Nutrition Examination survey 2nd year (2008)" which center for disease control is investigating. The general characteristics include age, educational level, occupation and marital status as factors affecting the metabolic syndrome of workers in this study. Results: Work-related factors are the working environment in which they are working while they are pressed for time due to work status and overload. If the work status of worker is unpaid family member, the risk is increased by more than twice compared to paid workers. The risk for metabolic syndrome in work environment to work while fighting the clock is decreased compared to the work environment without time pressure. Conclusion: In order to manage the metabolic syndrome of workers, health promotion program to change management of both working condition and working environment can contribute to prevent the metabolic syndrome and ultimately prevent the cerebrocardiovascular diseases.

• 대한임상검사과학회지
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• 제44권2호
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• pp.86-96
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• 2012

The high sensitivity C-reactive protein (hs-CRP) as one of the typical acute phase reactants is used for predictive factor of the cardiovascular disease and diabetes mellitus. In addition, there are claims that must be included as factors of metabolic syndrome. This research examined the relationship between the concentration of hs-CRP in blood and risk factors of the metabolic syndrome by gender, and the rates of metabolic syndrome depending on the hs-CRP level based on the general public who took the comprehensive medical check-up at Chonbuk National University Hospital in the Jeonbuk province. The subjects aged 17-87 years were participated, and 2,000 people were included as the final subjects except the persons with more than 10 mg/L of the hs-CRP of blood level. The hs-CRP concentrations increased according to the number of risk factors of metabolic syndrome in both men and women. In regards to the risk ratio of metabolic syndrome based on hs-CRP level in blood according to gender, the risk ratio increased by 3.07 times in male and 4.55 times in female intermediate risk group and 3.60 times in male and 6.15 times in female high risk group compared to hs-CRP low risk group. As a result, there was a proportional relation between hs-CRP level and the occurrence of metabolic syndrome, and it occurs more frequently among women than men.

• 한국건강관리협회지
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• 제2권1호
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• pp.71-76
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• 2004

The Metabolic syndrome is a constellation of lipid and non-lipid factors of metabolic origin. The presence of any 3 of the following factors is considered sufficient for diagnosis : hypertension(BP <130/85mmHg), low HDL-cholesterol (<40mg% in men, <50mg% in woman), high triglyceride(>150mg%) and abdominal obesity(abdominal girth >102cm in men, 88cm in woman). The major adverse consequence of the metabolic syndrome is cardiovascular disease. Several studies have shown an association between metabolic syndrome and increased cardiovascular events. In Korea, the prevalence of the factor of metabolic syndrome has been increasing since 20 years previously when the Korean economy began to grow rapidly, with a resultant change in lifestyle, toward that of western countries. Thus, the management of the metabolic syndrome is an important social and medical issue in terms of the national health problem. This review will consider each factor in turn, providing insight for health care providers in an effort to prevention of cardiovascular events and maintenance of quality of life in persons with metabolic syndrome was discussed.

• 한국전자통신학회논문지
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• 제8권4호
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• pp.639-648
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• 2013

대사증후군은 심혈관 질환에 큰 위험인자이며, 대사증후군을 가진 사람의 삶의 질은 저하될 수밖에 없을 것으로 판단된다. 따라서 우리나라 19세 이상 성인 여자를 대상으로 위험인자의 수, 각 위험인자별 이상 유무와 삶의 질과의 관계를 파악하고자 한다. 본 연구는 국민건강영양조사 제4기 1차년도와 제4기 2차년도의 자료를 통합하였고, 연구의 대상자 4,365명을 최종 분석 대상자로 하였다. 자료 분석은 Version 17.0 한글판 SPSS 통계 프로그램을 이용하였으며, 통계적 유의성은 p<0.05로 정의하였다. 본 연구의 대사증후군 유병률은 24.2%였다. 대사증후군의 위험 요인수가 1개인 경우의 삶의 질에 대한 회귀계수는 -0.024, 2개인 경우는 -0.048, 3개인 경우는 -0.090, 4개인 경우는 -0.117, 5개인 경우는 -0.168이었다. 위험요인들의 회귀계수는 허리둘레 -0.035. 혈압은 -0.064, 공복혈당은 -0.026, HDL콜레스테롤은 -0.012이었다. 결론적으로 대사증후군과 그 위험요인이 여성의 삶의 질 저하에 영향을 주고 있어서 이에 대한 중재가 요구되며, 향후 대사증후군에 영향을 미치는 다른 요인들과 삶의 질의 인과관계를 명확히 밝히는 연구를 통해 삶의 질 회복을 위한 방안이 필요하다고 사료된다.

• Journal of Preventive Medicine and Public Health
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• 제39권3호
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• pp.235-242
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• 2006

Objectives: We wanted to determine the distribution of the clustering of the metabolic risk factors and we wanted to evaluate the related factors in young schoolchildren. Methods: A cross-sectional study of metabolic syndrome was conducted in an elementary school in Seoul, Korea. We evaluated fasting glucose, triglyceride, HDL cholesterol, blood pressures and the body mass index, and we used parent-reported questionnaires to assess the potential risk factors in 261 children (136 boys, 125 girls). We defined the metabolic risk factors as obesity or at risk for obesity ($\geqq$ 85th percentile for age and gender), a systolic or diastolic blood pressure at $\geqq90th$ percentile for age and gender, fasting glucose at $\geqq110mg/dl$, triglyceride at $\geqq110mg/dl$ and HDL cholesterol at $\leqq40mg/dl$. Results: There were 15.7% of the subjects who showed clustering of two or more metabolic risk factors, 2.3% of the subjects who showed clustering for three or more risk factors, and 0.8% of the subjects who showed clustering for four or more risk factors. A multivariate analysis revealed that a father smoking more than 20 cigarettes per day, a mother with a body mass index of = $25kg/m^2$, and the child eating precooked or frozen food more than once per day were associated with clustering of two or more components, with the odds ratios of 3.61 (95% CI=1.24-10.48), 5.50 (95% CI=1.39-21.73) and 8.04 (95% CI=1.67-38.81), respectively. Conclusions: This study shows that clustering of the metabolic risk factors is present in young schoolchildren in Korea, with the clustering being associated with parental smoking and obesity as well as the child's eating behavior. These results suggest that evaluation of metabolic risk factors and intervention for lifestyle factors may be needed in both young Korean children and their parents.

• Biomolecules & Therapeutics
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• 제31권6호
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• pp.583-598
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• 2023

Dementia is a clinical syndrome characterized by progressive impairment of cognitive and functional abilities. As currently applied treatments for dementia can only delay the progression of dementia and cannot fundamentally cure it, much attention is being paid to reducing its incidence by preventing the associated risk factors. Cardiovascular and metabolic diseases are well-known risk factors for dementia, and many studies have attempted to prevent dementia by treating these risk factors. Growing evidence suggests that sex-based factors may play an important role in the pathogenesis of dementia. Therefore, a deeper understanding of the differences in the effects of drugs based on sex may help improve their effectiveness. In this study, we reviewed sex differences in the impact of therapeutics targeting risk factors for dementia, such as cardiovascular and metabolic diseases, to prevent the incidence and/or progression of dementia.

• Journal of Korean Biological Nursing Science
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• 제15권4호
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• pp.237-246
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• 2013

Purpose: A few Korean studies have reported that low urine acidity and hyperuricemia are related to metabolic syndrome. Therefore, we evaluated the relationships between urine pH, serum Uric Acid (UA), and metabolic risk factors in university students. Methods: Data were obtained from student health examinations in one university. Participants were 3,412 male and 4,214 female students. Descriptive statistics, t-test, logistic regressions and multiple logistic regression using SPSS version 18.0 were performed. Results: No significant relationship was found between metabolic risk factors and urine pH. From the univariate analysis, serum UA was significantly higher in obese ($BMI{\geq}25$), elevated blood pressure ($SBP{\geq}130$ and $DBP{\geq}85$), and higher triglyceride (${\geq}150$) groups for males and in obese, higher triglyceride and fasting blood sugar (${\geq}100$), and lower HDL-cholesterol (<50) groups for females. From the results of multivariate analysis, age, BMI, and triglyceride were significantly related to serum UA in males, BMI and HDL-cholesterol were significantly related to serum UA in females. Conclusion: Although there was no significant relationship between urinary pH and metabolic risk factors, significant associations between some of the metabolic risk factors and serum UA were found in the young adult population. Further studies are required to know the exact pathway between serum UA and metabolic syndrome.

• Nutrition Research and Practice
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• 제9권2호
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• pp.199-206
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• 2015

BACKGROUND/OBJECTIVE: Even though the prevalence of metabolic syndrome in adolescents is increasing, little is presently known about this syndrome in adolescents. This study aimed to cluster metabolic risk factors as well as examine the associations between identified patterns and nutrient intake using data from the Korean National Health Examination and Nutritional Assessment (KNHANES). SUBJECTS/METHODS: A total of 2,958 subjects aged 10 to 18 years along with both biochemical and dietary data information were obtained from KNHANES 2007-2010. Six components of metabolic syndrome were used to identify any patterns via factor analysis. Individuals were categorized into quartile groups according to their pattern score. RESULTS: Three clustering patterns with high loadings were identified and named as follows: 1) high blood pressure, 2) dyslipidemia, and 3) glucose abnormality patterns. The high blood pressure pattern showed high loadings of systolic and diastolic blood pressures, the dyslipidemia pattern showed high loadings of triglyceride and HDL-cholesterol levels, and the glucose abnormality pattern showed high loadings of fasting blood glucose levels. Intakes of fat and riboflavin were significantly decreased, whereas those of sodium and niacin were significantly increased across the quartiles in the dyslipidemia pattern. No nutrient intake except that of thiamin was significantly associated with the high blood pressure or glucose abnormality pattern. CONCLUSION: Our findings show that metabolic syndrome risk factors in the Korean adolescent population are characterized by three distinct patterns, which are differentially associated with dietary factors. Characterizing metabolic risk factors and providing specific dietary guidelines for target groups are important.

• 한국농촌간호학회지
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• 제2권1호
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• pp.51-59
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• 2007

Purpose: The purpose of this study was to examine the effects of a 12 week walking program on the risk factors associated with metabolic syndrome in older people in rural areas. Method: A total of 31 people among the people who live within the area served by E County Community Health Practice were observed from December 5, 2006 to February 23, 2007. This group included 18 people who were identified as having metabolic syndrome on the basis of the Asia-Pacific fatness basic standard (the experimental group) and a control group of 13 people who did not have metabolic syndrome. Results: The results of the study are as follows: In the experimental group, there was no significant difference in body composition between pre and post measurement. The small change in values that were observed in the experimental group did not reach statistical significance. However, body composition values in the control group increased. In the experimental group, there were significant differences in waist circumference, blood pressure, HDL-C, and fasting blood sugar between pre and post measurement. But there were no changes in the control group. There was no difference in TG in either group. As to changes in risk-factors related metabolic syndrome after the 12 week walking program, the number of risk-factors were effectively reduced in the experimental group, but not in the control group. Conclusion: According to the present study, a 12 week walking program led to significant improvement in body weight, BMI as the factors composing the body and in waist circumference, HDL-C, blood pressure, and fasting blood sugar as risk-factors related to metabolic syndrome in older people in rural areas.