• Title/Summary/Keyword: Meta-data

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Correlations Between Serum IL33 and Tumor Development: a Meta-analysis

  • Chen, Xiang-Jun;Huang, Ying-De;Li, Nian;Chen, Min;Liu, Fang;Pu, Dan;Zhou, Tao-You
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3503-3505
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    • 2014
  • Background: Interleukin-33 (IL-33) has recently been implicated in tumor development. Methods: Data was obtained from PubMed, EMBASE, Clinical trial, Cochrane Library, Web of Science, CNKI and Wanfang databases. After quality assessment and data extraction, a meta-analysis was performed using Review Manager 5.2 software. Results: There were eight documents included in this meta-analysis. The results showed IL33 levels to be higher in tumor patients than that in health people, but no correlations tumor stage, metastasis and survival time of tumor patients were evident. Conclusion: IL33 may be useful as an alarm factor in tumor detection and prognosis.

Clinicopathological Factors and Gastric Cancer Prognosis in the Iranian Population: a Meta-analysis

  • Somi, Mohammad Hossein;Ghojazadeh, Morteza;Bagheri, Masood;Tahamtani, Taraneh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.853-857
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    • 2015
  • Background: Gastric cancer is the most common cancer in the Iranian population. The aim of this study was to determine the effect of clinicopathological factors on prognosis by meta-analysis. Materials and Methods: A literature search was conducted using MEDLINE, EMBASE and Cochrane library and extensive literature search using the Persian databases until February 2011. Prospective follow up studies with multivariate analysis of overall survival of the patients with gastric cancer were included in this review. The data were analyzed by CMA.2. Publication bias are checked by funnel plot and data are shown as Forest plots. Results: From a total of 63 articles, 14 retrospective studies which examined 5 prognostic factors and involving 10,500 patients were included. Tumor size (>35mm) was the main significant factor predicting an unfavorable prognosis for the patients with gastric cancer (RR=1.829, p<0.001) followed by presence of distant metastases (RR=1.607, p<0.001), poor differentiation (RR=1.408, p<0.001) and male sex (RR=1.194, p<0.001). Lymph node metastases (RR=1.058, p=0.698) and moderate differentiation (RR=0.836, p=0.043) were not statistically significant as prognostic factors. Conclusions: This meta-analysis suggests that tumor size>35mm, poor differentiation, presence of distant metastasis and male gender are strongly associated with a poor prognosis in Iranian patients with gastric cancer.

Meta-regression analysis for anti-diabetic effect of green tea (녹차의 항-당뇨 효과에 대한 메타회귀분석)

  • Yun, A-Reum;Choi, Ki-Heon
    • Journal of the Korean Data and Information Science Society
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    • v.22 no.4
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    • pp.717-726
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    • 2011
  • The present study was carried out to summarize the effect of green tea in the diabetic rats by meta-analysis related studies. The association measure to test effect of green tea was Hedges' standardized mean difference. In this particular fixed effect model, body weight was significantly increased. Also, blood glucose, triglycerides were significantly decreased. In this case of heterogeneous variable, random effect model was applied. In this model, body weight was significantly increased. Also, blood glucose was significantly decreased in green tea treated group. According to the Meta-regression analysis, duration of injection was not significant for variables.

A Popularity-driven Cache Management and its Performance Evaluation in Meta-search Engines (메타 검색 엔진을 위한 인기도 기반 캐쉬 관리 및 성능 평가)

  • Hong, Jin-Seon;Lee, Sang-Ho
    • Journal of KIISE:Databases
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    • v.29 no.2
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    • pp.148-157
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    • 2002
  • Caching in meta-search engines can improve the response time of users' request. We describe the cache scheme in our meta-search engine in terms of its architecture and operational flow. In particular, we propose a popularity-driven cache algorithm that utilizes popularities of queries to determine cached data to be purged. The popularity is a value that represents the normalized occurrence frequency of user queries. This paper presents how to collect popular queries and how to calculate query popularities. An empirical performance evaluation of the popularity-driven caching with the traditional schemes (i.e., least recently used (LRU) and least frequently used (LFU)) has been carried out on a collection of real data. In almost all cases, the proposed replacement policy outperforms LRU and LFU.

Generate of OCL on XML Sechma Meta Model (XML 스키마 메타모델에서 OCL 생성)

  • Lee Don-Yang;Choi Han-Yong
    • The Journal of the Korea Contents Association
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    • v.6 no.6
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    • pp.42-49
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    • 2006
  • XML used rapid method of meta language representation in internet for information transmission. In addition to XML Schema used frequency specification to variety data type. This thesis designed to Simple Type meta model of XML schema using UML. But because structure of XML schema complicate and suppose variety data type we can recognize many difficult matter to user's apprehension and application of model properties that appeared UML. To way out of this matter this study could specified clearly to structured expression in XML schema meta model that is applied OCL specification and together, come up with method of detailed design to parse tree and token generation for lexical and symmentics analysis in compile step on this study foundation.

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Effects of Self-management on Pain in Patients with Osteoarthritis: A Meta-analysis (자가관리중재가 골관절염 대상자의 통증에 미치는 효과: 메타분석)

  • Lee, Chun Hee
    • Journal of muscle and joint health
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    • v.26 no.3
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    • pp.155-166
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    • 2019
  • Purpose: This study was a meta-analysis of the effects of self-management on pain in patients with osteoarthritis. Methods: Randomized controlled trials were identified by searching PubMed, EMBASE, CINAHL, Ovid-MEDLINE and Korean database using key words, 'self-management', 'osteoarthritis' and 'pain'. Data were analyzed using the R version program. Results: Twenty nine studies met the inclusion criteria with a total of 5,998 participants. There were significant differences in overall effects of self-management (SMD -0.53, 95% CI -0.77~-0.29, p<.001). Conclusion: The results of the study show that self-management was effective in reducing pain in patients with osteoarthritis. As a result, it should be used as basic data when using self-management for patients with osteoarthritis.

Development of Data Profiling Software Supporting a Microservice Architecture (마이크로 서비스 아키텍처를 지원하는 데이터 프로파일링 소프트웨어의 개발)

  • Chang, Jae-Young;Kim, Jihoon;Jee, Seowoo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.21 no.5
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    • pp.127-134
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    • 2021
  • Recently, acquisition of high quality data has become an important issue as the expansion of the big data industry. In order to acquiring high quality data, accurate evaluation of data quality should be preceded first. The quality of data can be evaluated through meta-information such as statistics on data, and the task to extract such meta-information is called data profiling. Until now, data profiling software has typically been provided as a component or an additional service of traditional data quality or visualization tools. Hence, it was not suitable for utilizing directly in various environments. To address this problem, this paper presents the development result of data profiling software based on a microservice architecture that can be serviced in various environments. The presented data profiler provides an easy-to-use interface that requests of meta-information can be serviced through the restful API. Also, a proposed data profiler is independent of a specific environment, thus can be integrated efficiently with the various big data platforms or data analysis tools.

Stimulation-Oriented Interventions for Behavioral Problems among People with Dementia: A Systematic Review and Meta-Analysis (치매 환자의 문제행동을 위한 자극지향적 중재의 효과 연구: 체계적 고찰과 메타분석)

  • Kim, Eun Young;Hwang, Sung-Dong;Kim, Eun Joo
    • Journal of Korean Academy of Nursing
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    • v.46 no.4
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    • pp.475-489
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    • 2016
  • Purpose: This study was a systematic review and meta-analysis designed to investigate the effects of stimulation-oriented interventions for behavioral problems among people with dementia. Methods: Based on the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA), a literature search was conducted using seven electronic databases, gray literature, and other sources. Methodological quality was assessed using the Scottish Intercollegiate Guidelines Network (SIGN) for randomized controlled trials (RCTs). Data were analyzed using R with the 'meta' package and the Comprehensive Meta-Analysis (CMA 2.0) program. Results: Sixteen studies were included for meta-analysis to investigate the effect of stimulation-oriented interventions. The quality of individual studies was rated as '++' for eight studies and '+' for the rest. The effect sizes were analyzed according to three subgroups of interventions (light, music, and others); Hedges' g=0.04 (95% CI: -0.38~0.46), -0.23 (95% CI: -0.56~0.10), -0.34 (95% CI: -0.34~0.00), respectively. To explore the possible causes of heterogeneity ($I^2=62.8%$), meta-regression was conducted with covariates of sample size, number of sessions, and length of session (time). No moderating effects were found for sample size or number of sessions, but session time showed a significant effect (Z=1.96, 95% CI: 0.00~0.01). Finally, a funnel plot along with Egger's regression test was performed to check for publication bias, but no significant bias was detected. Conclusion: Based on these findings, stimulation-oriented interventions seem to have a small effect for behavioral problems among people with dementia. Further research is needed to identify optimum time of the interventions for behavioral problems among dementia pateints.

The RTEL1 rs6010620 Polymorphism and Glioma Risk: a Meta-analysis Based on 12 Case-control Studies

  • Du, Shu-Li;Geng, Ting-Ting;Feng, Tian;Chen, Cui-Ping;Jin, Tian-Bo;Chen, Chao
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10175-10179
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    • 2015
  • Background: The association between the RTEL1 rs6010620 single nucleotide polymorphism (SNP) and glioma risk has been extensively studied. However, the results remain inconclusive. To further examine this association, we performed a meta-analysis. Materials and Methods: A computerized search of the PubMed and Embase databases for publications regarding the RTEL1 rs6010620 polymorphism and glioma cancer risk was performed. Genotype data were analyzed in a meta-analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the association. Sensitivity analyses, tests of heterogeneity, cumulative meta-analyses, and assessments of bias were performed in our meta-analysis. Results: Our meta-analysis confirmed that risk with allele A is lower than with allele G for glioma. The A allele of rs6010620 in RTEL1 decreased the risk of developing glioma in the 12 case-control studies for all genetic models: the allele model (OR=0.752, 95%CI: 0.715-0.792), the dominant model (OR=0.729, 95%CI: 0.685-0.776), the recessive model (OR=0.647, 95%CI: 0.569-0.734), the homozygote comparison (OR=0.528, 95%CI: 0.456-0.612), and the heterozygote comparison (OR=0.761, 95%CI: 0.713-0.812). Conclusions: In all genetic models, the association between the RTEL1 rs6010620 polymorphism and glioma risk was significant. This meta-analysis suggests that the RTEL1 rs6010620 polymorphism may be a risk factor for glioma. Further functional studies evaluating this polymorphism and glioma risk are warranted.

Correlations among Meta Cognition, Critical Thinking and Self-efficacy of Nursing Students Studying through Problem Based Learning(PBL) (문제중심학습법으로 학습한 간호학생의 메타인지, 비판적 사고력, 자기효능감간의 관계)

  • Hwang, Yoon-Young;Park, Chang-Seong;Chu, Min-Sun
    • Research in Community and Public Health Nursing
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    • v.18 no.1
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    • pp.146-155
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    • 2007
  • Purpose: This study was performed to examine the degree of meta cognition, critical thinking and self-efficacy and to identify correlations among the meta cognition, critical thinking, and self-efficacy of nursing students studying through PBL. Method: The subjects were 140 nursing students who had studied through PBL over three terms at C College. Data were collected from August to September, 2005 using a structured questionnaire and analyzed using SPSS 10.0. Results: The mean score of meta cognition was 40.14 (SD=6.02), critical thinking was 181.46 (SD=14.49), and self-efficacy was 942.93 (SD=167.05). There was a statistically significant positive correlation between meta cognition and self-efficacy and age. Also, meta cognition had a positive correlation with appropriateness to nursing and interest in nursing knowledge, and critical thinking had a positive correlation with appropriateness to nursing, interest in nursing knowledge, interest in lab on campus and interest in clinical practicum. There were statistically significant positive correlations among meta cognition, critical thinking and self-efficacy. Conclusion: Based on above results, further research should be done about many factors influencing nursing students' problem solving abilities for the development and application of many teaching methods for improving nursing students' meta cognition, critical thinking and self-efficacy.

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